publicações selecionadas
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artigo académico
- Repetitive mRNA vaccination is required to improve the quality of broad-spectrum anti-SARS-CoV-2 antibodies in the absence of CXCL13.. Science Advances. 2023
- Post-acute sequelae of COVID-19 is characterized by diminished peripheral CD8+ß7 integrin+ T cells and anti-SARS-CoV-2 IgA response. Nature Communications. 2023
- Highly tailorable gellan gum nanoparticles as a platform for the development of T cell activator systems. Biomaterials Research. 2022
- Low quantity and quality of anti-spike humoral response is linked to CD4 T-cell apoptosis in COVID-19 patients. Cell Death and Differentiation. 2022
- IL-10 Overexpression After BCG Vaccination Does Not Impair Control of Mycobacterium tuberculosis Infection.. Frontiers in Immunology. 2022
- T cell apoptosis characterizes severe Covid-19 disease. Cell Death and Differentiation. 2022
- Dysregulation of glycerophospholipid metabolism during Behçet's disease contributes to a pro-inflammatory phenotype of circulating monocytes. Emerging Microbes & Infections. 2021
- Early IL-10 promotes vasculature associated CD4+ T cells unable to control Mycobacterium tuberculosis infection. JCI Insight. 2021
- Interleukin-6 Is a Biomarker for the Development of Fatal Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia. Frontiers in Immunology. 2021
- Immune System Efficiency in Cancer and the Microbiota Influence. Pathobiology. 2021
- Changes in the Immune Phenotype and Gene Expression Profile Driven by a Novel Tuberculosis Nanovaccine: Short and Long-Term Post-immunization. Frontiers in Immunology. 2021
- Interleukin-10 induces interferon-¿-dependent emergency myelopoiesis. Cell Reports. 2021
- Mycobacterium tuberculosis associated with severe tuberculosis evades cytosolic surveillance systems and modulates IL-1ß production. Nature Communications. 2020
- The Absence of HIF-1a Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis. Cell Reports. 2020
- Myeloid HIF-1a regulates pulmonary inflammation during experimental Mycobacterium tuberculosis infection. Immunology. 2020
- A Nonribosomal Peptide Synthase Gene Driving Virulence in Mycobacterium tuberculosis. Msphere. 2018
- IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity. Journal of Allergy and Clinical Immunology. 2017
- Analysis of a Local HIV-1 Epidemic in Portugal Highlights Established Transmission of Non-B and Non-G Subtypes. J. Clin. Microbiol.. 2015
- Cutting edge: IFN-¿ regulates the induction and expansion of IL-17-producing CD4 T cells during mycobacterial infection. Journal of Immunology. 2006
- Anti-interleukin 10 receptor monoclonal antibody is an adjuvant for T helper cell type 1 responses to soluble antigen only in the presence of lipopolysaccharide. Journal of Experimental Medicine. 2000
- Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): Differential expression and responsiveness in Th1 and Th2 cells. Journal of Immunology. 1999
- Endogenously produced IL-12 is required for the induction of protective T cells during Mycobacterium avium infections in mice. Journal of Immunology. 1995
- Erratum: Role of gamma interferon and tumor necrosis factor alpha during T-cell-independent and -dependent phases of Mycobacterium avium infection (Infection and Immunity 62:9 (3969)). Infection and Immunity. 1995
- In vivo evidence for a non-T cell origin of interleukin-5. Scandinavian Journal of Immunology. 1995
- Susceptibility of beige mice to Mycobacterium avium: Role of neutrophils. Infection and Immunity. 1995
- The relative impact of bacterial virulence and host genetic background on cytokine expression during Mycobacterium avium infection of mice. Immunology. 1995
- Tumour necrosis factor-alpha (TNF-a) in the host resistance to mycobacteria of distinct virulence. Clinical and Experimental Immunology. 1995
- Characterization of the virulence of Mycobacterium avium complex (MAC) isolates in mice. Clinical and Experimental Immunology. 1994
- Neutrophils as effector cells of T-cell-mediated, acquired immunity in murine listeriosis. Immunology. 1994
- Role of gamma interferon and tumor necrosis factor alpha during T-cell- independent and -dependent phases of Mycobacterium avium infection. Infection and Immunity. 1994
- Role of interleukin-6 in the induction of protective T cells during mycobacterial infections in mice. Immunology. 1994
- Live but not heat-killed mycobacteria cause rapid chemotaxis of large numbers of eosinophils in vivo and are ingested by the attracted granulocytes. Infection and Immunity. 1991
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artigo de conferência
- In vivo evaluation of the suitability of starch-based scaffolds for bone tissue engineering constructs using adipose derived adult stem cells and transgenic mice 2008
- Injectable gellan gum hydrogels as supports for cartilage tissue engineering applications: In vitro characterization and initial in vivo studies 2008
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artigo de revista
- Interleukin-8 and Interleukin-6 Are Biomarkers of Poor Prognosis in Esophageal Squamous Cell Carcinoma. Cancers. 2023
- Study of the immunologic response of marine-derived collagen and gelatin extracts for tissue engineering applications. Acta Biomaterialia. 2022
- Increased CD3+, CD8+, or FoxP3+ T Lymphocyte Infiltrations Are Associated with the Pathogenesis of Colorectal Cancer but Not with the Overall Survival of Patients. Biology. 2021
- Towards the Development of a Female Animal Model of T1DM Using Hyaluronic Acid Nanocoated Cell Transplantation: Refinements and Considerations for Future Protocols. Pharmaceutics. 2021
- Antimicrobial activity of Mycobacteriophage D29 Lysin B during Mycobacterium ulcerans infection. PLoS Neglected Tropical Diseases. 2019
- Predictors and outcomes of disseminated tuberculosis in an intermediate burden setting. Chest. 2019
- TNF-mediated compensatory immunity to mycobacterium avium in the absence of macrophage activation by IFN-¿. Journal of Immunology. 2019
- The impact of IL-10 dynamic modulation on host immune response against visceral leishmaniasis. Cytokine. 2018
- L-Threonine Supplementation During Colitis Onset Delays Disease Recovery. Frontiers in Physiology. 2018
- The Dynamics of Interleukin-10-Afforded Protection during Dextran Sulfate Sodium-Induced Colitis. Frontiers in Immunology. 2018
- High systemic IL-6 is associated with worse prognosis in patients with non-small cell lung cancer. Antibiotics. 2017
- Interferon-ß regulates the production of IL-10 by toll-like receptor-activated microglia. Glia. 2017
- A Prediction Rule to Stratify Mortality Risk of Patients with Pulmonary Tuberculosis. Antibiotics. 2016
- Balancing the immune response in the brain: IL-10 and its regulation. Journal of Neuroinflammation. 2016
- Delivery of LLKKK18 loaded into self-assembling hyaluronic acid nanogel for tuberculosis treatment. Journal of Controlled Release. 2016
- Type i IFN inhibits alternative macrophage activation during mycobacterium tuberculosis infection and leads to enhanced protection in the absence of IFN-¿ signaling. Journal of Immunology. 2016
- Spontaneous Healing of Mycobacterium ulcerans Lesions in the Guinea Pig Model. PLoS Neglected Tropical Diseases. 2015
- IL-17A Promotes Intracellular Growth of Mycobacterium by Inhibiting Apoptosis of Infected Macrophages. Frontiers in Immunology. 2015
- BCG vaccination-induced long-lasting control of Mycobacterium tuberculosis correlates with the accumulation of a novel population of CD4<sup>+</sup>IL-17<sup>+</sup>TNF<sup>+</sup>IL-2<sup>+</sup> T cells. Vaccine. 2015
- Myeloid Sirtuin 2 Expression Does Not Impact Long-Term Mycobacterium tuberculosis Control.. Antibiotics. 2015
- Differential post-transcriptional regulation of IL-10 by TLR2 and TLR4-activated macrophages. European Journal of Immunology. 2014
- Mycobacterium tuberculosis Strains Are Differentially Recognized by TLRs with an Impact on the Immune Response. Antibiotics. 2013
- Phage Therapy Is Effective against Infection by Mycobacterium ulcerans in a Murine Footpad Model. PLoS Neglected Tropical Diseases. 2013
- Vascular Endothelial Growth Factor and Fibroblast Growth Factor-2 Incorporation in Starch-Based Bone Tissue-Engineered Constructs Promote theIn VivoExpression of Neovascularization Mediators. Tissue Engineering. Part C: Methods. 2013
- Evidence for Diversifying Selection in a Set of Mycobacterium tuberculosis Genes in Response to Antibiotic- and Nonantibiotic-Related Pressure. Molecular Biology and Evolution. 2013
- Chondrogenic potential of two hASCs subpopulations loaded onto gellan gum hydrogel evaluated in a nude mice model. Current Stem Cell Research & Therapy. 2013
- In Vivo Performance of Chitosan/Soy-Based Membranes as Wound-Dressing Devices for Acute Skin Wounds. Tissue Engineering. Part C: Methods. 2013
- P. brasiliensis Virulence Is Affected by SconC, the Negative Regulator of Inorganic Sulfur Assimilation. Antibiotics. 2013
- Poor Immune Reconstitution in HIV-Infected Patients Associates with High Percentage of Regulatory CD4(+) T Cells. Antibiotics. 2013
- TLR9 Activation Dampens the Early Inflammatory Response to Paracoccidioides brasiliensis, Impacting Host Survival. PLoS Neglected Tropical Diseases. 2013
- Corticosteroid-Induced Immunosuppression Ultimately Does Not Compromise the Efficacy of Antibiotherapy in Murine Mycobacterium ulcerans Infection. PLoS Neglected Tropical Diseases. 2012
- Cellular Immunity Confers Transient Protection in Experimental Buruli Ulcer following BCG or Mycolactone-Negative Mycobacterium ulcerans Vaccination. Antibiotics. 2012
- Local and Regional Re-Establishment of Cellular Immunity during Curative Antibiotherapy of Murine Mycobacterium ulcerans Infection. Antibiotics. 2012
- Differential arabinan capping of lipoarabinomannan modulates innate immune responses and impacts T helper cell differentiation. Journal of Biological Chemistry. 2012
- Osteogenic differentiation of two distinct subpopulations of human adipose-derived stem cells: An in vitro and in vivo study. International Review of Neurobiology. 2012
- The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma. Genes and Immunity. 2012
- The C Allele of rs5743836 Polymorphism in the Human TLR9 Promoter Links IL-6 and TLR9 Up-Regulation and Confers Increased B-Cell Proliferation. Antibiotics. 2011
- Mycobacterium ulcerans Triggers T-Cell Immunity followed by Local and Regional but Not Systemic Immunosuppression. Infection and Immunity. 2011
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TLR2 deficiency by compromising p19 (IL-23) expression limits T
h 17 cell responses to Mycobacterium tuberculosis. International Immunology. 2011 - Chitosan Improves the Biological Performance of Soy-Based Biomaterials. Tissue Engineering. Part C: Methods. 2010
- The selective COX-2 inhibitor Etoricoxib reduces acute inflammatory markers in a model of neurogenic laryngitis but loses its efficacy with prolonged treatment. Inflammation Research. 2010
- Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis. Journal of Experimental Medicine. 2010
- Dissemination of mycobacteria to the thymus renders newly generated T cells tolerant to the invading pathogen. Journal of Immunology. 2010
- Gellan Gum Injectable Hydrogels for Cartilage Tissue Engineering Applications: In Vitro Studies and Preliminary In Vivo Evaluation. International Review of Neurobiology. 2010
- IFN-g–Dependent Activation of Macrophages during Experimental Infections by Mycobacterium ulcerans Is Impaired by the Toxin Mycolactone. Journal of Immunology. 2010
- In vivo short-term and long-term host reaction to starch-based scaffolds. Acta Biomaterialia. 2010
- Plasmacytoid and conventional dendritic cells are early producers of IL-12 in Neospora caninum-infected mice. Immunology and Cell Biology. 2010
- Virulence attenuation of Candida albicans genetic variants isolated from a patient with a recurrent bloodstream infection. Antibiotics. 2010
- Cdc42p controls yeast-cell shape and virulence of Paracoccidioides brasiliensis. Fungal Genetics and Biology. 2009
- Performance of new gellan gum hydrogels combined with human articular chondrocytes for cartilage regeneration when subcutaneously implanted in nude mice. International Review of Neurobiology. 2009
- Developments on Drug Delivery Systems for the Treatment of Mycobacterial Infections. Current Topics in Medicinal Chemistry. 2008
- First Cultivation and Characterization of Mycobacterium ulcerans from the Environment. PLoS Neglected Tropical Diseases. 2008
- A New Model of Laryngitis: Neuropeptide, Cyclooxygenase, and Cytokine Profile. Laryngoscope. 2008
- IL-10 modulates depressive-like behavior. Journal of Psychiatric Research. 2008
- Strategies for use of IL-10 or its antagonists in human disease. Immunological Reviews. 2008
- In vitro evaluation of the behaviour of human polymorphonuclear neutrophils in direct contact with chitosan-based membranes. Antibiotics. 2007
- Mycolactone-Mediated Inhibition of Tumor Necrosis Factor Production by Macrophages Infected withMycobacterium ulceransHas Implications for the Control of Infection. Infection and Immunity. 2007
- Evidence for an Intramacrophage Growth Phase ofMycobacterium ulcerans. Infection and Immunity. 2007
- Analysis of the immune response to Neospora caninum in a model of intragastric infection in mice. Parasite Immunology. 2007
- Neospora caninum: High susceptibility to the parasite in C57BL/10ScCr mice. Experimental Parasitology. 2007
- Breakpoints in immunoregulation required for Th1 cells to induce diabetes. European Journal of Immunology. 2006
- Infection with Mycobacterium ulcerans Induces Persistent Inflammatory Responses in Mice. Infection and Immunity. 2005
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