publicações selecionadas
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artigo académico
- Reply to Dietvorst et al. Challenges in Providing an Overview of Results of Intermittent Fasting Interventions on Diabetes Parameters. Comment on “Silva et al. Effects of Intermittent Fasting on Regulation of Metabolic Homeostasis: A Systematic Review and Meta-Analysis in Health and Metabolic-Related Disorders. J. Clin. Med. 2023, 12, 3699”. Journal of Clinical Medicine. 2024
- Prevascularized spongy-like hydrogels maintain their angiogenic potential after prolonged hypothermic storage. Bioactive Materials. 2024
- Antimicrobial properties of hindered amine light stabilizers in polymer coating materials and their mechanism of action. Frontiers in Bioengineering and Biotechnology. 2024
- In vitro neuronal and glial response to magnetically stimulated piezoelectric poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV)/cobalt ferrite (CFO) microspheres. Biomaterials Advances. 2024
- Inflammation and Exosomes in Fabry Disease Pathogenesis. Cells. 2024
- Secretome of Bone Marrow Mesenchymal Stromal Cells Cultured in a Dynamic System Induces Neuroprotection and Modulates Microglial Responsiveness in an a-Synuclein Overexpression Rat Model. Cytotherapy. 2024
- Effects of Lactate Transport Inhibition by AZD3965 in Muscle-Invasive Urothelial Bladder Cancer. Pharmaceutics. 2023
- The Yeast Protein Kinase Sch9 Functions as a Central Nutrient-Responsive Hub That Calibrates Metabolic and Stress-Related Responses. Journal of Fungi. 2023
- Effects of Intermittent Fasting on Regulation of Metabolic Homeostasis: A Systematic Review and Meta-Analysis in Health and Metabolic-Related Disorders. Journal of Clinical Medicine. 2023
- Current and Emerging Techniques for Diagnosis and MRD Detection in AML: A Comprehensive Narrative Review. Cancers. 2023
- The nutrient-responsive CDK Pho85 primes the Sch9 kinase for its activation by TORC1 2023
- Innovative, integrative, and interactive in-class activity on metabolic regulation: Evaluating educational impacts. Biochemistry and Molecular Biology Education. 2021
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021
- The antifungal plant defensin HsAFP1 induces autophagy, vacuolar dysfunction and cell cycle impairment in yeast. Biochimica et Biophysica Acta (BBA). Biomembranes. 2020
- Elucidating the mechanisms of action of parecoxib in the MG-63 osteosarcoma cell line. Anti-Cancer Drugs. 2020
- Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology. Cell Death & Diff. 2019
- AMPK in Pathogens. EXS. 2016
- Longevity pathways and maintenance of the proteome: the role of autophagy and mitophagy during yeast ageing. Microbial Cell. 2014
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artigo de revista
- Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization. International Journal of Molecular Sciences. 2023
- Anti-Aging and Neuroprotective Properties of Grifola frondosa and Hericium erinaceus Extracts. Nutrients. 2022
- Functional Genetic Variants in ATG10 Are Associated with Acute Myeloid Leukemia. Cancers. 2021
- Polymorphisms within Autophagy-Related Genes Influence the Risk of Developing Colorectal Cancer: A Meta-Analysis of Four Large Cohorts. Cancers. 2021
- Unravelling the anticancer potential of functionalized chromeno[2,3-b]pyridines for breast cancer treatment. Bioorganic Chemistry. 2020
- Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot. Biology. 2020
- Transcriptomic and chemogenomic analyses unveil the essential role of Com2-regulon in response and tolerance of Saccharomyces cerevisiae to stress induced by sulfur dioxide. Microbial Cell. 2019
- Targeting Metabolic Reprogramming in Acute Myeloid Leukemia. Cells. 2019
- a-Synuclein toxicity in yeast and human cells is caused by cell cycle re-entry and autophagy degradation of ribonucleotide reductase 1. Aging Cell. 2019
- Yeast at the Forefront of Research on Ageing and Age-Related Diseases. Progress in Molecular and Subcellular Biology. 2019
- Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology. Cell Death and Differentiation. 2018
- Exploitation of New Chalcones and 4H-chromenes as Agents for Cancer Treatment. European Journal of Medicinal Chemistry. 2018
- Signalling mechanisms that regulate metabolic profile and autophagy of acute myeloid leukaemia cells. Journal of Cellular and Molecular Medicine. 2018
- Linking cellular proteostasis to yeast longevity. FEMS Yeast Research. 2018
- Caloric restriction rescues yeast cells from alpha-synuclein toxicity through autophagic control of proteostasis. Aging-Us. 2018
- Lipocalin-2 regulates adult neurogenesis and contextual discriminative behaviours. Elife. 2018
- Cell sheet engineering using the stromal vascular fraction of adipose tissue as a vascularization strategy. Acta Biomaterialia. 2017
- Caloric restriction alleviates alpha-synuclein toxicity in aged yeast cells by controlling the opposite roles of Tor1 and Sir2 on autophagy. Mechanisms of Ageing and Development. 2017
- Increasing the Fungicidal Action of Amphotericin B by Inhibiting the Nitric Oxide-Dependent Tolerance Pathway. Oxidative Medicine and Cellular Longevity. 2017
- Mitochondrial proteomics of the acetic acid - induced programmed cell death response in a highly tolerant Zygosaccharomyces bailii - derived hybrid strain. Microbial Cell. 2016
- Sirtuins and Proteolytic Systems: Implications for Pathogenesis of Synucleinopathies. Biomolecules. 2015
- Bioresorbable ureteral stents from natural origin polymers. Journal of Biomedical Materials Research: Part B. 2015
- Proteolytic systems and AMP-activated protein kinase are critical targets of acute myeloid leukemia therapeutic approaches. Oncotarget. 2014
- Proteomic Analysis of the Action of the Mycobacterium ulcerans Toxin Mycolactone: Targeting Host Cells Cytoskeleton and Collagen. PLoS Neglected Tropical Diseases. 2014
- Involvement of Yeast HSP90 Isoforms in Response to Stress and Cell Death Induced by Acetic Acid. Antibiotics. 2013
- DNA replication stress-induced loss of reproductive capacity inS. cerevisiaeand its inhibition by caloric restriction. Cell Cycle. 2013
- SNCA (a-synuclein)-induced toxicity in yeast cells is dependent on Sir2-mediated mitophagy. Autophagy. 2012
- An alternative respiratory pathway on Candida krusei: implications on susceptibility profile and oxidative stress. FEMS Yeast Research. 2012
- Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a specific substrate of yeast metacaspase. Biochimica Et Biophysica Acta-Molecular Cell Research. 2011
- Yeast chronological lifespan and proteotoxic stress: Is autophagy good or bad?. Biochemical SocIETy Transactions. 2011
- Accumulation of Non-Superoxide Anion Reactive Oxygen Species Mediates Nitrogen-Limited Alcoholic Fermentation by Saccharomyces cerevisiae. Applied and Environmental Microbiology. 2010
- Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H 2 O 2 and superoxide dismutase activity. Proceedings of the National Academy of Sciences of the United States of America. 2010
- Cdc42p controls yeast-cell shape and virulence of Paracoccidioides brasiliensis. Fungal Genetics and Biology. 2009
- Neurodevelopmental delay in the Cln3¿ex7/8 mouse model for Batten disease. Genes, Brain and Behavior. 2009
- Drug-induced apoptosis in yeast. Biochimica Et Biophysica Acta-Molecular Cell Research. 2008
- NO-mediated apoptosis in yeast. Journal of Cell Science. 2007
- An atypical active cell death process underlies the fungicidal activity of ciclopirox olamine against the yeast Saccharomyces cerevisiae. FEMS Yeast Research. 2007
- Low auxotrophy-complementing amino acid concentrations reduce yeast chronological life span. Mechanisms of Ageing and Development. 2007
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capítulo de livro
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documento
- Long-Term Hypothermic Storage Preserves Angiogenic Potential of Prevascularized Spongy-Like Hydrogels 2024
- Noradrenergic Degeneration in a DJ-1 Knockout mouse model 2024
- Effects of the non-sugar sweeteners xylitol and sucralose on Saccharomyces cerevisiae chronological lifespan 2023
- The action of the sweeteners cyclamate and saccharin on the chronological aging of Saccharomyces cerevisiae 2023
- Synthesis of chromene[2,3-b]pyridines and characterization of their anticancer potential for the treatment of breast cancer 2023
- Síntese de cromeno[2,3-b]piridinas e caracterização do seu potencial anticancerígeno para o tratamento do cancro da mama 2023
- Detecção não invasiva de doença residual mínima em leucemia mielóide aguda usando um sistema de microfluídica para o isolamento e concentração de blastos leucémicos em sangue periférico ou em médula óssea 2021
- Isolation and concentration of acute myeloid leukemia blasts in measurable residual disease using a microfluidic system 2021
- A new lead compound for triple negative breast cancer therapy 2021
- New chromene derivatives: overcoming renal cell carcinoma drug resistance 2021
- A new therapeutic option for triple negative breast cancer 2021
- Novel therapy for renal cell carcinoma: overcoming drug resistance 2021
- Isolation of Acute Myeloid Leukemia Blasts Using a Microfluidic System for Accurate Assessment of Minimal Residual Disease 2021
- Characterization of the biological activity of functionalized chromeno[2,3-b]pyridines for breast cancer treatment 2020
- Unravelling the anticancer potential of novel compounds for breast cancer therapy 2020
- Characterization of the biological activity of functionalized chromeno[2,3b]pyridines for breast cancer treatment 2020
- Desenvolvimento de uma plataforma de microfluídica para diagnóstico e monitorização de doença residual mínima em leucemia mielóide aguda 2020
- New chromene derivatives: unravelling the molecular mechanisms for breast cancer treatment 2019
- CLINICAL IMPLICATIONS OF THE AUTOPHAGY CORE GENE VARIATIONS IN ACUTE MYELOID LEUKEMIA 2019
- INTEGRATION OF LIPID METABOLISM WITH KREBS CYCLE IN ACUTE MYELOID LEUKEMIA§ 2019
- Exploitation of novel chromene derivatives for breast cancer treatment 2019
- Exploitation of novel chromene derivatives for breast cancer treatment. 2019
- New chromene-based molecules for renal cell cancer therapy 2019
- New molecules based on chromene moiety as candidates for renal cell carcinoma therapy 2019
- Novas moléculas baseadas na unidade de cromeno como candidatas à terapia do carcinoma das células renais (CCR). 2019
- New chromene derivatives: Unraveling the molecular mechanisms for breast cancer therapy 2019
- Chromene-based compounds as candidates for renal cell cancer treatment 2019
- Chromene-based compounds as candidates for renal cell cancer treatment. 2019
- New chromene derivatives: Unraveling the molecular mechanisms for breast cancer therapy. 2019
- Biological activity of novel targeted inhibitors for renal cell cancer therapy 2019
- Biological activity of novel targeted inhibitors for renal cell cancer therapy. 2019
- In vitro and in vivo evaluation of new chromene derivatives as potent anticancer agents 2019
- In vitro and in vivo evaluation of new chromene derivatives as potent anticancer agents. 2019
- A microfluidics platform for the SERS-based detection of acute myeloid leukemia 2019
- Uncovering the molecular mechanisms that tie autophagy and UPS during ageing 2019
- New chromene-based molecules as microtubule destabilizers and pro-apoptotic agents in cancer 2018
- Chemical and biological characterization of chalcones and 4H-chromenes: exploitation as anticancer agents 2018
- Chemical and biological characterization of chalcones and 4H-chromenes: exploitation as anticancer agents. 2018
- Unraveling the anticancer molecular mechanisms of new chromene-based drugs 2018
- Discovery of chromene-based molecules as apoptosis-inducers by G2/M cell-arrest 2018
- Discovery of chromene-based molecules as apoptosis-inducers by G2/M cell-arrest. 2018
- Unraveling the anticancer molecular mechanisms of new chromene-based drugs. 2018
- Chromene-based drug candidates for cancer treatment 2018
- Caloric restriction alleviates a-synuclein toxicity in aged yeast cells through regulation of proteolytic systems 2018
- Caloric restriction coordinately balances the proteolytic systems activity during aging of yeast cells expressing alpha-synuclein. 2018
- Chromene-based drug candidates for cancer treatment. 2018
- Effects of charged side chain amino acids supplementation on a- synuclein-mediated toxicity 2018
- Interplay between energetic metabolism and autophagic regulation in acute myeloid leukemia cells 2018
- Interplay between glutaminolysis and autophagy in acute myeloid leukemia cells 2018
- Messenger molecules modulating yeast chronological aging 2018
- Cell signaling pathways and autophagy regulation in acute myeloid leukemia 2017
- Coordinate regulation of autophagy and proteasome mediates chronological lifespan extension by caloric restriction 2017
- Energy metabolism in acute myeloid leukemia cells 2017
- Glutaminolysis and autophagy interplay in acute myeloid leukemia cells 2017
- Metabolic cell signalling pathways and autophagy regulation in acute myeloid leukemia cells 2017
- Functioning of autophagy on acute myeloid leukemia patients 2016
- Proteolytic systems function on acute myeloid leukemia patients: relation with metabolic disorders 2016
- Proteolytic systems as important targets of acute myeloid leukemia therapeutic approaches 2015
- The TOR pathway and Sirtuin 2 collaborate in the regulation of autophagy of caloric restricted aged cells 2014
- Transcriptional regulation of autophagy during yeast chronological aging by nutrient-sensing players 2013
- Alpha-synuclein-induced toxicity is dependent on Sir2-mediated mitophagy in yeast aged cells 2012
- Caloric restriction regulates autophagy in yeast aged cells in response to proteotoxicity 2012
- HSP90: endogenous modulators of yeast acetic acid-induced apoptotic cell death 2011
- Heterologous expression of alpha-synuclein, wild-type and A53T mutant form, induces autophagy in yeast 2011
- Heterologous expression of the expanded form of ataxin-3 induces cell death in yeast 2011
- Mitophagy is contributing to alpha-synuclein, wild- type and A53T mutant form, toxicity in aged cells 2011
- The role of HSP90 in yeast acetic acid-induced apoptosis 2011
- Aconitase as target of degradation during oxidative stress induced apoptosis in Saccharomyces cerevisiae 2009
- Cdc42p controls yeast-cell shape and virulence of Paracoccidioides brasiliensis 2009
- Expression of the Paracoccidioides brasiliensis CDC42 homolog in Saccharomyces cerevisiae triggers a multiple budding phenotype 2009
- Deletion of HBN1 results in yeast aberrant mitochondrial morphology and chronological life span extension 2008
- Glyceraldehyde-3- phosphate dehydrogenase as a crucial mediator of Saccharomyces cerevisiae apoptotic cell death 2008
- Singular yeast cell morphology of Paracoccidioides brasiliensis is associated to virulence: down-regulation of the CDC42 homolog 2008
- Studying the role of nitric oxide in the pathological mechanism of Batten disease 2008
- Evidence for NO-mediated apoptosis in yeast 2007
- Molecular bases for Paracoccidioides brasiliensis multiple budding cellular division: a role for the small Rho-like GTPase Cdc42p 2007
- Suvival/Death of Saccharomyces cerevisiae stationary phase cells: nutrients effect 2007
- Essential amino acid supplementation of auxotrophic yeast strains determines lifespan and oxidative stress resistance 2006
- Essential amino acids determine lifespan in yeast 2006
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teses