publicações selecionadas
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artigo académico
- An Injectable Composite Co-Assembled Dehydropeptide-Based Magnetic/Plasmonic Lipogel for Multimodal Cancer Therapy. Advanced Functional Materials. 2024
- Synthesis and Characterisation of Dimeric Bolaamphiphilic Dehydrodipeptides for Biomedical Applications. Materials Proceedings. 2020
- New cyclic RGD peptides: synthesis, characterization, and theoretical activity towards avß3 integrin. Tetrahedron. 2014
- Ga[NO2A-N-(a-amino)propionate] chelates: synthesis and evaluation as potential tracers for 68Ga PET. Dalton Transactions. 2014
- Ln[DO3A-N-a-(pyrenebutanamido)propionate] complexes: optimized relaxivity and NIR optical properties. Dalton Transactions. 2014
- Thermodynamic stability and relaxation studies of small, triaza-macrocyclic Mn(ii) chelates. Dalton Transactions. 2013
- Synthesis and electrochemical behaviour of ß-halodehydroamino acid derivatives. Amino Acids. 2010
- Studies of encapsulation of a new potential antitumoral indole derivative in nanoliposomes for drug delivery applications. European Cells & Materials. 2010
- Gd(DO3A-N-a-aminopropionate): a versatile and easily available synthon with optimized water exchange for the synthesis of high relaxivity, targeted MRI contrast agents. Chemical Communications. 2009
- New synthesis of methyl 5-aryl or heteroaryl pyrrole-2-carboxylates by a tandem Sonogashira coupling/5-endo-dig-cyclization from ß-iododehydroamino acid methyl esters and terminal alkynes. Tetrahedron. 2008
- New strategies for the synthesis of heteroannulated 2-pyridinones, substituted 2-quinolinones and coumarins from dehydroamino acid derivatives. Tetrahedron. 2008
- Synthesis of new heteroaryl and heteroannulated indoles from dehydrophenylalanines: Antitumor evaluation. Bioorganic & Medicinal Chemistry. 2008
- A Thieno-2H-chromene a-Amino Acid Derivative: Synthesis and Photochromic Properties. Organic Letters. 2005
- New fluorescent benzo[b]thienyl amino acid derivatives based on sulfanylphenyl benzo[b]thiophenes. Journal of Photochemistry and Photobiology A-Chemistry. 2005
- New ß,ß-Bis(benzo[b]thienyl)dehydroalanine Derivatives: Synthesis and Cyclization. European Journal of Organic Chemistry. 2003
- Synthesis of Novel Amino Acids and Dehydroamino Acids Containing the Benzo[b]thiophene Moiety. European Journal of Organic Chemistry. 2003
- Synthesis Using Suzuki Cross Couplings of Sulfur Analogues of Dehydrotryptophan with a Definite Stereochemistry. European Journal of Organic Chemistry. 2002
- Michael addition of thiols, carbon nucleophiles and amines to dehydroamino acid and dehydropeptide derivatives. Journal of the Chemical SocIETy-Perkin Transactions 1. 2001
- Synthesis of novel ß-substituted a,ß-dehydroamino acid derivatives. Tetrahedron Letters. 2000
- Novel aziridine esters by the addition of aromatic nitrogen heterocycles to a 2H-azirine-3-carboxylic ester. Tetrahedron Letters. 2000
- Efficient synthesis of dehydroamino acid derivatives. Tetrahedron Letters. 1998
- The use of electrochemical methods for deprotection during peptide synthesis. Review of Clinical Pharmacology and Pharmacokinetics, International Edition. 1995
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artigo de conferência
- Hydrogels and Nanostructures Formed from Ciprofloxacin Peptide Conjugates 2023
- New 2,6-Bis(5-phenyloxazolyl)pyridine Ligands for Luminescent LnIII Complexes 2022
- Core-shell magnetic-plasmonic nanoparticles enclosed in a biocompatible dehydropeptide-based hydrogel containing lysine. Proceedings of SPIE. 2019
- Characterization of organic matter at different stages of a composting process 2019
- Influence of the feedstock material on the compost maturity, stability and reactivity 2019
- Synthesis of new dehydroamino acids using coppercatalyzed C-N couplings 2011
- Electrochemical reduction of beta-aryldehydroamino acid derivatives 2010
- High yield synthesis of heterocyclic beta-substituted alanine derivatives 1999
- Stereoselective synthesis of dehydroaminobutyric acid 1998
- Preparative dehydration of serine and threonine in peptides 1998
- Efficient preparation of dehydroalanine derivatives 1998
- New Synthesis of Dehydroalanine Derivatives 1998
- Selective Cleavage of Protecting Groups in Arginine 1994
- Preparative Cathodic Cleavage of Amine Protecting Groups 1993
- Investigation of Amino Acid Racemization During Cathodic Cleavage of Protecting Groups 1990
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artigo de revista
- Unveiling the Role of Capping Groups in Naphthalene N-Capped Dehydrodipeptide Hydrogels. Gels. 2023
- Fisetin derivatives exhibit enhanced anti-inflammatory activity and modulation of endoplasmic reticulum stress. International Immunopharmacology. 2023
- Tuning Peptide-Based Hydrogels: Co-Assembly with Composites Driving the Highway to Technological Applications. International Journal of Molecular Sciences. 2023
- Oxidative Precipitation Synthesis of Calcium-Doped Manganese Ferrite Nanoparticles for Magnetic Hyperthermia. International Journal of Molecular Sciences. 2022
- Peptide-Based Supramolecular Hydrogels as Drug Delivery Agents: Recent Advances. Gels. 2022
- Aryl-Capped Lysine-Dehydroamino Acid Dipeptide Supergelators as Potential Drug Release Systems. International Journal of Molecular Sciences. 2022
- Plasmonic lipogels: driving co-assembly of composites with peptide-based gels for controlled drug release. Soft Matter. 2022
- Tuning the drug multimodal release through a co-assembly strategy based on magnetic gels. Nanoscale. 2022
- An injectable, naproxen-conjugated, supramolecular hydrogel with ultra-low critical gelation concentration - prepared from a known folate receptor ligand. Soft Matter. 2022
- Bolaamphiphilic Bis-Dehydropeptide Hydrogels as Potential Drug Release Systems. Gels. 2021
- Evaluation of a Model Photo-Caged Dehydropeptide as a Stimuli-Responsive Supramolecular Hydrogel. Nanomaterials. 2021
- Dehydropeptide Supramolecular Hydrogels and Nanostructures as Potential Peptidomimetic Biomedical Materials. International Journal of Molecular Sciences. 2021
- Supramolecular ultra-short carboxybenzyl-protected dehydropeptide-based hydrogels for drug delivery. Journal of Nanoparticle Research. 2021
- Impact of Citrate and Lipid-Functionalized Magnetic Nanoparticles in Dehydropeptide Supramolecular Magnetogels: Properties, Design and Drug Release. Nanomaterials. 2020
- Magnetoliposomes Incorporated in Peptide-Based Hydrogels: Towards Development of Magnetolipogels. Nanomaterials. 2020
- Biological Evaluation of Naproxen Dehydrodipeptide Conjugates with Self-Hydrogelation Capacity as Dual LOX/COX Inhibitors. Pharmaceutics. 2020
- Dehydropeptide-based plasmonic magnetogels: a supramolecular composite nanosystem for multimodal cancer therapy. Journal of Materials Chemistry B. 2020
- Exploring the properties and potential biomedical applications of NSAID-capped peptide hydrogels. Soft Matter. 2020
- Magnetic Dehydrodipeptide-Based Self-Assembled Hydrogels for Theragnostic Applications. Nanomaterials. 2019
- Novel dehydropeptide-based magnetogels containing manganese ferrite nanoparticles as antitumor drug nanocarriers. Physical Chemistry Chemical Physics. 2019
- Magnetogels: Prospects and Main Challenges in Biomedical Applications. Pharmaceutics. 2018
- Toxicity and structure-activity relationship (SAR) of a,ß-dehydroamino acids against human cancer cell lines. Toxicology in Vitro. 2018
- Synthesis and preliminary biological evaluation of new phenolic and catecholic dehydroamino acid derivatives. Tetrahedron. 2017
- Self-assembled RGD dehydropeptide hydrogels for drug delivery applications. Journal of Materials Chemistry B. 2017
- Interaction of fluorescent quinolin-2-one and coumarin derivatives including dipeptides with lipid bilayers. Nanoscale. 2016
- Dehydrodipeptide Hydrogelators Containing Naproxen N-Capped Tryptophan: Self-Assembly, Hydrogel Characterization, and Evaluation as Potential Drug Nanocarriers. Biomacromolecules. 2015
- PEGylated DOTA-AHA-Based GdIIIChelates: A Relaxometric Study. European Journal of Inorganic Chemistry. 2015
- Dinuclear DOTA-Based GdIIIChelates - Revisiting a Straightforward Strategy for Relaxivity Improvement. European Journal of Inorganic Chemistry. 2015
- Gold nanoparticles functionalised with fast water exchanging Gd3+ chelates: linker effects on the relaxivity. Dalton Transactions. 2015
- New self-assembled supramolecular hydrogels based on dehydropeptides. Journal of Materials Chemistry B. 2015
- Synthesis and photophysical studies of new pyrenylamino acids. Tetrahedron. 2013
- Synthesis of Fluorescent Alanines by a Rhodium-Catalysed Conjugate Addition of Arylboronic Acids to Dehydroalanine Derivatives. European Journal of Organic Chemistry. 2013
- Amide conjugates of the DO3A-N-(a-amino)propionate ligand: leads for stable, high relaxivity contrast agents for MRI?. Contrast Media & Molecular Imaging. 2012
- Interaction of antitumoral fluorescent heteroaromatic compounds, a benzothienopyrrole and two thienoindoles, with DNA and lipid membranes. Journal of Photochemistry and Photobiology A-Chemistry. 2012
- Synthesis of new ß-amidodehydroaminobutyric acid derivatives and of new tyrosine derivatives using copper catalyzed C–N and C–O coupling reactions. Amino Acids. 2012
- Synthesis of 2,6-Bis(oxazolyl)pyridine Ligands for Luminescent LnIII Complexes. European Journal of Organic Chemistry. 2012
- Gold nanoparticles functionalised with stable, fast water exchanging Gd3+ chelates as high relaxivity contrast agents for MRI. Dalton Transactions. 2012
- Phenanthrenyl-indole as a fluorescent probe for peptides and lipid membranes. Journal of Photochemistry and Photobiology A-Chemistry. 2011
- Electrochemical reduction of dehydroamino acids: Synthesis and photophysical properties of ß,ß-diarylalanines. Tetrahedron. 2011
- Nanoliposomes for encapsulation and delivery of the potential antitumoral methyl 6-methoxy-3-(4-methoxyphenyl)-1H-indole-2-carboxylate. Nanoscale Research Letters. 2011
- Gallium labeled NOTA-based conjugates for peptide receptor-mediated medical imaging. Bioorganic & Medicinal Chemistry Letters. 2010
- A mild high yielding synthesis of oxazole-4-carboxylate derivatives. Tetrahedron. 2010
- Synthesis and Photophysical Studies of New Fluorescent Indole Derivatives Obtained from beta-Bromodehydroamino Acids. Interaction with Fluoride Anions. European Journal of Organic Chemistry. 2010
- Fluorescence properties of a potential antitumoral benzothieno[3,2-b]pyrrole in solution and lipid membranes. Journal of Photochemistry and Photobiology A-Chemistry. 2009
- Synthesis and Photophysical Studies of a Pyrenylindole and a Phenalenoindole Obtained from Dehydroamino Acid Derivatives - Application as Fluorescent Probes for Biological Systems. European Journal of Organic Chemistry. 2009
- Comparative effect ofN-substituted dehydroamino acids and a-tocopherol on rat liver lipid peroxidation activities. Journal of Enzyme Inhibition and Medicinal Chemistry. 2009
- Fluorescence Studies on Potential Antitumoral Heteroaryl and Heteroannulated Indoles in Solution and in Lipid Membranes. Journal of Fluorescence. 2009
- Synthesis of bis-amino acid derivatives by Suzuki cross-coupling, Michael addition and substitution reactions. Amino Acids. 2009
- Pyrenylamino Acids: Synthesis, Photophysical and Electrochemical Studies. European Journal of Organic Chemistry. 2008
- Synthesis of Substituted Oxazoles fromN-Acyl-ß-hydroxyamino Acid Derivatives. European Journal of Organic Chemistry. 2008
- New tetracyclic heteroaromatic compounds based on dehydroamino acids: photophysical and electrochemical studies of interaction with DNA. Tetrahedron. 2008
- Reactivity of Dehydroamino Acids and Dehydrodipeptides TowardsN-Bromosuccinimide: Synthesis of ß-Bromo- and ß,ß-Dibromodehydroamino Acid Derivatives and of Substituted 4-Imidazolidinones. European Journal of Organic Chemistry. 2007
- Synthesis of new 3-arylindole-2-carboxylates using ß,ß-diaryldehydroamino acids as building blocks. Fluorescence studies. Tetrahedron. 2007
- Synthesis and Reactivity of ß-Bromo-ß-Substituted Dehydroalanines. European Journal of Organic Chemistry. 2006
- Synthesis of ß-Benzo[b]thienyldehydrophenylalanine Derivatives by One-Pot Palladium-Catalyzed Borylation and Suzuki Coupling (BSC) and Metal-Assisted Intramolecular Cyclization - Studies of Fluorescence and Antimicrobial Activity. European Journal of Organic Chemistry. 2005
- Synthesis of pure stereoisomers of benzo[b]thienyl dehydrophenylalanines by Suzuki cross-coupling. Preliminary studies of antimicrobial activity. Tetrahedron. 2004
- Sonogashira Cross-Couplings of Dehydroamino Acid Derivatives and Phenylacetylenes. European Journal of Organic Chemistry. 2004
- Synthesis and reactivity of a 1,4-dihydropyrazine derivative. Tetrahedron. 2004
- Synthesis and intramolecular cyclization of novel ß,ß-bis-(benzo[b]thienyl)dehydroalanine derivatives. Tetrahedron Letters. 2003
- Electrochemical synthesis of diaminodicarboxylic acid derivatives. Tetrahedron Letters. 2003
- Palladium-catalyzed borylation and Suzuki coupling (BSC) to obtain ß-substituted dehydroamino acid derivatives. Tetrahedron Letters. 2003
- Synthesis of Non-Natural Amino Acids from N-(p-Tolylsulfonyl)-a,ß-didehydroamino Acid Derivatives. European Journal of Organic Chemistry. 2003
- Synthesis of non-proteinogenic amino acids from N-(4-toluenesulfonyl)dehydroamino acid derivatives. Tetrahedron Letters. 2002
- Synthesis of 2,3,5-substituted pyrrole derivatives. Tetrahedron Letters. 2002
- Synthesis of ß-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives. Journal of the Chemical SocIETy-Perkin Transactions 1. 2000
- High yielding synthesis of heterocyclic ß-substituted alanine derivatives. Tetrahedron Letters. 1999
- High yielding synthesis of dehydroamino acid and dehydropeptide derivatives. Journal of the Chemical SocIETy-Perkin Transactions 1. 1999
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capítulo de livro
- Progress in multifunctional and multimodal biomaterials for therapeutic applications 2024
- Advances in Nanotheranostics with Plasmonic and Magnetic Nanoparticles 2021
- N, N-diprotected dehydroamino acid derivatives: Versatile substrates for the synthesis of novel amino acids 2006
- Palladium-catalysed borylation and suzuki coupling (BSC) to obtain ß-benzo[B]thienyldehydroamino acid derivatives 2004
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documento
- Versatile magneto-plasmonic composites based on dehydropeptide hydrogels for multimodal cancer therapy 2023
- Design of self assembled magnetic/plasmonic lipogels for multimodal cancer therapy 2023
- New architectures in soft materials for combined cancer therapy 2022
- Self-assembly of bolaamphiphiles based on dehydropeptides 2022
- Hydrogels featuring magnetic properties based on self-assembled dehydropeptides 2021
- NEW ARCHITECTURES IN SOFT MATERIALS FOR COMBINED CANCER THERAPY: Multifunctional dehydrodipeptide-based hydrogels with magneto-plasmonic properties 2021
- Implications of nanoparticles functionalization in supramolecular magnetogels for drug delivery 2021
- Bolaamphiphilic Bis-Dehydropeptide Hydrogels as Potential Drug Release Systems 2021
- Boolaamphiphilic dehydrodipeptide hydrogels for drug delivery applications (10.21814/1822.70576) 2021
- Supramolecular magnetogels: Advances towards on-demand drug release 2020
- Magnetolipogels: a combined strategy for controlled drug release 2020
- Novel ultra short peptide hydrogel as a potential drug nanocarrier 2019
- Core-shell magnetic-plasmonic nanoparticles enclosed in biocompatible hydrogels for multimodal cancer therapy 2019
- Benzyloxycarbonyldehydropeptides hydrogelators for drug delivery 2019
- Magnetogels based on magnetic/plasmonic nanoparticles and self-assembled peptide hydrogels as drug nanocarriers 2019
- New magnetogels based on manganese ferrite nanoparticles and self-assembled peptide hydrogels as drug nanocarriers 2017
- Bis-dehydroamino acid derivatives as hydrogelators 2017
- A new RGD dehydropeptide with hydrogelation properties 2012
- Synthesis and self-assembly of new N-protected dehydropeptides 2012
- Novos Hidrogéis peptídicos para aplicações biomédicas 2012
- Synthesis and triggered gelation of a new dehydropeptide 2011
- Dehydropeptides N-Conjugated with Naproxen as Hydrogelators 2011
- Synthesis of new 2,6-bis-(oxazole)pyridine ligand as a sensitizer for luminescent Ln(III) complexes 2011
- Synthesis of new cyclic RGD peptides by click chemistry 2010
- High yielding synthesis of oxazole-4-carboxylates from dehydroamino acid derivatives. Application as fluorescent markers for peptides 2010
- Synthesis of new bis-amino acids derivatives 2010
- Synthesis of new chemosensors for fluoride ion from dehydroamino acid derivatives 2009
- Synthesis of new fluorescent amino acids 2009
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teses