publicações selecionadas
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artigo académico
- Screening of novel ASOs against Tau protein - shifting isoforms. Molecular Therapy. 2024
- Dynamic representation of appetitive and aversive stimuli in nucleus accumbens shell D1- and D2-medium spiny neurons. Nature Communications. 2024
- Physiological and behavioral contagion/buffering effects of chronic unpredictable stress in a socially enriched environment: A preliminary study. Neurobiology of Stress. 2024
- Nucleus accumbens neurons dynamically respond to appetitive and aversive associative learning. Journal of Neurochemistry. 2024
- Glucocorticoid receptor-dependent therapeutic efficacy of tauroursodeoxycholic acid in preclinical models of Spinocerebellar ataxia type 3. Journal of Clinical Investigation. 2024
- Glucocorticoid receptor-dependent therapeutic efficacy of tauroursodeoxycholic acid in preclinical models of Spinocerebellar ataxia type 3 (IF: 19.47). The Journal of Clinical Investigation. 2024
- Treating Parkinson¿'isease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Administration. Cells. 2023
- A novel perspective on the role of nucleus accumbens neurons in encoding associative learning. FEBS Letters. 2023
- Involvement of nucleus accumbens D2¿medium spiny neurons projecting to the ventral pallidum in anxiety-like behaviour. Journal of Psychiatry & Neuroscience. 2023
- A novel isolation method for spontaneously released extracellular vesicles from brain tissue and its implications for stress-driven brain pathology. Cell Communication and Signaling. 2023
- Ventral pallidal regulation of motivated behaviors and reinforcement. Frontiers in Neural Circuits. 2023
- Home-cage behavior is impacted by stress exposure in rats. Elife. 2023
- Involvement of nucleus accumbens D2-MSN projections to the ventral pallidum in anxious-like behaviour. Journal of Psychiatry & Neuroscience. 2023
- Loss of function of Tau in the adult brain leads to synaptic dysfunction through nucleosome destabilization. Nature. 2023
- Reduction of Tau in the adult brain dysregulates epigenetic homeostasis and neuroplasticity. Nature Genetics. 2023
- Screening of novel ASOs against Tau protein - shifting isoforms 2023
- Prenatal dexamethasone exposure alters effort decision making and triggers nucleus accumbens and anterior cingulate cortex functional changes in male rats. Elife. 2022
- The Duration of Stress Determines Sex Specificities in the Vulnerability to Depression and in the Morphologic Remodeling of Neurons and Microglia. Elife. 2022
- Distinct role of nucleus accumbens D2-MSN projections to ventral pallidum in different phases of motivated behavior. Cell Reports. 2022
- Alteration on effort decision making in a model of prenatal stress: NAc and ACC functional changes. Journal of Neurochemistry. 2022
- Integration of behavior and neuronal physiology in a mouse model of Rett Syndrome: a focus on serotonergic system modulation. Journal of Neurochemistry. 2022
- Involvement of nucleus accumbens D2-MSN projections to the ventral pallidum in anxious-like behavior. BioRxiv. 2022
- Involvement of nucleus accumbens D2-MSN projections to the ventral pallidum in anxious-like behaviour. Elife. 2022
- Laterodorsal tegmentum-Nucleus accumbens projections underlie cocaine-induced preference. Journal of Neurochemistry. 2022
- Young Members Symposia. Journal of Neurochemistry. 2022
- Laterodorsal tegmentum–ventral tegmental area projections encode positive reinforcement signals. Journal of Neuroscience Research. 2021
- Resilience to stress and sex-specific remodeling of microglia and neuronal morphology in a rat model of anxiety and anhedonia. Neurobiology of Stress. 2021
- Constitutive deficiency of the neurogenic hippocampal modulator AP2¿ promotes anxiety-like behavior and cumulative memory deficits in mice from juvenile to adult periods. Elife. 2021
- Splenic sympathetic signaling contributes to acute neutrophil infiltration of the injured spinal cord. Journal of Neuroinflammation. 2020
- Signatures of brain criticality unveiled by maximum entropy analysis across cortical states. Physical Review E. 2020
- Allosteric modulation of AMPA receptors counteracts Tau-related excitotoxic synaptic signaling and memory deficits in Stress and Aß-evoked hippocampal pathology. Elife. 2020
- Correction: Nucleus accumbens medium spiny neurons subtypes signal both reward and aversion. Elife. 2019
- Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology. Cell Death & Diff. 2019
- Impairments in laterodorsal tegmentum to VTA projections underlie glucocorticoid-triggered reward deficits.. Elife. 2017
- Activation of D1 and D2-expressing neurons in the nucleus accumbens enhances motivation. Brain Structure and Function. 2016
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artigo de revista
- Preclinical Assessment of Mesenchymal-Stem-Cell-Based Therapies in Spinocerebellar Ataxia Type 3. Biomedicines. 2021
- Unilateral Intrastriatal 6-Hydroxydopamine Lesion in Mice: A Closer Look into Non-Motor Phenotype and Glial Response. International Journal of Molecular Sciences. 2021
- Low-cost silicon neural probe: fabrication, electrochemical characterization and in vivo validation. Microsystem Technologies-Micro-and Nanosystems-Information Storage and Processing Systems. 2021
- Nucleus accumbens medium spiny neurons subtypes signal both reward and aversion. Elife. 2020
- Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors. Nature Communications. 2019
- Criticality between Cortical States. Physical Review Letters. 2019
- Region-specific control of microglia by adenosine A(2A) receptors: uncoupling anxiety and associated cognitive deficits in female rats. Glia. 2019
- Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology. Cell Death and Differentiation. 2018
- Endolysosomal degradation of Tau and its role in glucocorticoid-driven hippocampal malfunction. EMBO J. 2018
- Mild Prenatal Stress Causes Emotional and Brain Structural Modifications in Rats of Both Sexes. Acta Cytologica. 2018
- Neuroprotective Effects of Creatine in the CMVMJD135 Mouse Model of Spinocerebellar Ataxia Type 3. Movement Disorders. 2018
- Nucleus Accumbens Microcircuit Underlying D2-MSN-Driven Increase in Motivation.. Eneuro. 2018
- Impairments in laterodorsal tegmentum to VTA projections underlie glucocorticoid triggered reward deficits. Acta Cytologica. 2017
- Adenosine A 2A receptor regulation of microglia morphological remodeling-gender bias in physiology and in a model of chronic anxiety. Elife. 2017
- Coupled variability in primary sensory areas and the hippocampus during spontaneous activity. Acta Cytologica. 2017
- Effect of Levodopa on Reward and Impulsivity in a Rat Model of Parkinson's Disease. Acta Cytologica. 2017
- Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation. Nat Comms. 2016
- Reappraising striatal D1- and D2-neurons in reward and aversion. Neuroscience and Biobehavioral Reviews. 2016
- Combined therapy with m-TOR-dependent and -independent autophagy inducers causes neurotoxicity in a mouse model of Machado-Joseph disease. Neuroscience. 2016
- The impact of prenatal exposure to dexamethasone on gastrointestinal function in rats. Antibiotics. 2016
- Lithium Chloride Therapy Fails to Improve Motor Function in a Transgenic Mouse Model of Machado-Joseph Disease. Cerebellum. 2014
- The motivational drive to natural rewards is modulated by prenatal glucocorticoid exposure. Elife. 2014
- Chronic Treatment with 17-DMAG Improves Balance and Coordination in A New Mouse Model of Machado-Joseph Disease. Neurotherapeutics. 2014
- Dopaminergic Modulation of Affective and Social Deficits Induced by Prenatal Glucocorticoid Exposure. Neuropsychopharmacology. 2013
- Glucocorticoid Programing of the Mesopontine Cholinergic System. Frontiers in Endocrinology. 2013
- A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis. Journal of Cell Biology. 2012
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documento
- SNX27 Neuronal Silencing Impairs Cognitive Function and Increases Cocaine Sensitivity 2024
- Nucleus accumbens D2 medium spiny neuron projections to the ventral pallidum promote anxiety-like behaviour 2023
- Encoding of valence by nucleus accumbens neurons 2023
- SNX27 Ubiquitous and Hippocampal-Specific Deletion Impairs Cognitive Function 2023
- Glucocorticoid Receptor as a Biomarker and Neuronal Therapeutic Target of a Disease-Improving Bile Acid in SCA3/MJD 2022
- The Glucocorticoid Receptor as a Biomarker and Neuronal Therapeutic Target of a Disease-Improving Bile Acid in SCA3/MJD 2022
- Involvement of nucleus accumbens neurons in cue-reward associative learning 2022
- Alteration on effort decision making in a model of prenatal stress: NAc and ACC functional changes 2022
- Divergent role of nucleus accumbens D2-MSN-ventral pallidum projections in different phases of motivated behavior 2022
- Prenatal glucocorticoid exposure alters effort decision making and triggers nucleus accumbens and anterior cingulate cortex functional changes 2022
- Whole Brain Mapping of neuronal ensembles responsive to positive and negative stimuli 2022
- Constitutive AP2¿ deficiency reduces postnatal hippocampal neurogenesis and induces behavioral deficits in juvenile mice that persist during adulthood 2021
- Serotonergic Signalling Activation as a Therapeutic Approach for Neurodegenerative Diseases 2020
- Valence in the Nucleus Accumbens - Identifying Neural Populations in Appetitive and Aversive Responses 2020
- Distinct role of nucleus accumbens D2-MSN projections to ventral pallidum in different phases of motivated behavior 2020
- Role of Nucleus Accumbens Direct and Indirect Pathways in Anxiety- and Depressive-like Behaviors 2020
- Role of Nucleus Accumbens direct and indirect pathways in anxiety- and depressive-like behaviors 2019
- A Glucorticoid receptor-dependent mechanism of bile acid action with therapeutic impact in polyglutamine disease. 2019
- A Glucorticoid receptor-dependent mechanism of bile acid action with therapeutic impact in polyglutamine disease 2019
- Modulation of reward behaviors by nucleus accumbens indirect pathway 2019
- Prenatal glucocorticoid exposure alters microglia in a sex-specific manner and blunts stress-induced behavioral changes in adulthood 2019
- Role of D2-MSNs-to-VP projections in reward and anxiety 2018
- Brain region duality in the regulation of microglia morphology by adenosine A2A receptors: implications for anxiety and cognition 2017
- Chronic blockade of adenosine A2AReceptors: Gender-specific reprogramming of microglia morphology in the PFC 2017
- Modulation of microglia morphology by adenosine A2A receptors: impact for anxiety and cognition 2017
- Impact of selective manipulation of nucleus accumbens local microcircuits on D2-medium spiny neurons (MSN)-dependent increase in motivation 2017
- Impairments in laterodorsal tegmentum to VTA projections underlie glucocorticoid triggered reward deficits 2017
- Nucleus accumbens D2-dependent increase in motivation: impact of selective manipulation of local microcircuits 2017
- Reward deficits triggered by glucocorticoid exposure depend on laterodorsal tegmentum inputs to ventral tegmental area in rats 2017
- Reward deficits triggered by glucocorticoids are driven by laterodorsal tegmentum ventral tegmental area dysfunction 2017
- The “stressed” autophagy: chronic stress exacerbates Tau pathology by blocking autophagy clearance system 2016
- P.1.c.011 The modulation of reward-responses is dependent on dopamine D2 receptor activation in the nucleus accumbens 2015
- Anxiety caused by prenatal immunomodulation is paralleled by an atrophy of microglial processes in the pre-frontal cortex of female rats. 2015
- A molecular switch on a yeast arrestin-like protein connects glucose signalling to ubiquitin-dependent transporter endocytosis 2012
- Impact of prenatal synthetic glucocorticoid exposure on the adolescent brain
- Nucleus accumbens neurons dynamically encode positive and aversive associative learning
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teses