publicações selecionadas
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artigo académico
- A Label-Free Multitechnique Approach to Characterize the Interaction of Bioactive Compounds with Biomimetic Interfaces. Small Science. 2024
- A Stratum corneum lipid model as a platform for biophysical profiling of bioactive chemical interactions at the skin level. Journal of Molecular Liquids. 2024
- Recent Advances and Strategies for Nanocarrier-mediated Topical Therapy and Theranostic for Posterior Eye Disease. Advanced Drug Delivery Reviews. 2024
- Lipid Microfluidic Biomimetic Models for Drug Screening: A Comprehensive Review. Advanced Functional Materials. 2024
- Lyotropic liquid crystalline 2D and 3D mesophases: Advanced materials for multifunctional anticancer nanosystems. Biochimica et Biophysica Acta (BBA). Reviews on Cancer. 2023
- Nanostructured Lipid Carriers Enriched Hydrogels for Skin Topical Administration of Quercetin and Omega-3 Fatty Acid. Pharmaceutics. 2023
- Natural Compounds: Co-Delivery Strategies with Chemotherapeutic Agents or Nucleic Acids Using Lipid-Based Nanocarriers. Pharmaceutics. 2023
- Nanostructured lipid carriers enriched hydrogels for skin topi-cal administration of quercetin and omega-3 fatty acid. Pharmaceutics. 2023
- Oral delivery of camptothecin-loaded multifunctional chitosan-based micelles is effective in reduce colorectal cancer. Journal of Controlled Release. 2022
- Lipid Nanosystems and Serum Protein as Biomimetic Interfaces: Predicting the Biodistribution of a Caffeic Acid-Based Antioxidant. Nanotechnology, Science and Applications. 2021
- Prediction of paclitaxel pharmacokinetic based on in vitro studies: Interaction with membrane models and human serum albumin. International Journal of Applied Pharmaceutics. 2020
- Nucleic acid carrier composed of a branched fatty acid lysine conjugate - Interaction studies with blood components. Colloids and Surfaces B: Biointerfaces. 2019
- Self-assembled para-Nitroaniline polymeric thin films as highly efficient generators of second harmonic light. Optical Materials. 2019
- The influence of nanocrystal size on optical second harmonic generation by para-nitroanaline embedded in electro-spun polymeric fibers. Journal of Nanoparticle Research. 2018
- How Multi-Step versus One-Step Preparation Method Affects the Physicochemical Properties and Transfection Efficiency of DNA/DODAB: MO Lipoplexes. Journal of Applied Solution Chemistry and Modeling. 2014
- A biophysical approach to menadione membrane interactions: Relevance for menadione-induced mitochondria dysfunction and related deleterious/therapeutic effects. Biochimica et Biophysica Acta - Biomembranes (Impact Factor 2013: 3.431). 2013
- Biophysical characterization of the drug-membrane interactions: The case of propranolol and acebutolol. European Journal of Pharmaceutics and Biopharmaceutics (Impact Factor 2013: 4.245). 2013
- Brain targeting effect of camptothecin-loaded solid lipid nanoparticles in rat after intravenous administration. European Journal of Pharmaceutics and Biopharmaceutics (Impact Factor 2013: 4.245). 2013
- Differential interactions of rifabutin with human and bacterial membranes: Implication for its therapeutic and toxic effects. Journal of Medicinal Chemistry (Impact Factor 2013: 6.259). 2013
- Drug-membrane interaction studies applied to N'-acetyl-rifabutin. European Journal of Pharmaceutics and Biopharmaceutics (Impact Factor 2013: 4.245). 2013
- Effects of a novel antimycobacterial compound on the biophysical properties of a pulmonary surfactant model membrane. International Journal of Pharmaceutics (Impact Factor 2013: 3.649). 2013
- Evaluation of the structure-activity relationship of rifabutin and analogs: A drug-membrane study. ChemPhysChem (Impact Factor 2013: 3.360). 2013
- Imidazolium ionic liquids as solvents of pharmaceuticals: Influence on HSA binding and partition coefficient of nimesulide. International Journal of Pharmaceutics (Impact Factor 2013: 3.649). 2013
- Insights about a-tocopherol and Trolox interaction with phosphatidylcholine monolayers under peroxidation conditions through Brewster angle microscopy. Colloids and Surfaces B: Biointerfaces (Impact factor 2013: 4.287). 2013
- Interplay of mycolic acids, antimycobacterial compounds and pulmonary surfactant membrane: A biophysical approach to disease. Biochimica et Biophysica Acta - Biomembranes (Impact Factor 2013: 3.431). 2013
- Novel resveratrol nanodelivery systems based on lipid nanoparticles to enhance its oral bioavailability. International Journal of Nanomedicine (Impact Factor 2013: 4.383). 2013
- Synchrotron small angle X-ray scattering for the evaluation of the interaction of silica nanotubes with lipid membranes. RSC Advances (Impact Factor 2013: 3.708). 2013
- The influence of Rifabutin on human and bacterial membrane models: Implications for its mechanism of action. Journal of Physical Chemistry B (Impact Factor 2013: 3.377). 2013
- Interaction of celecoxib with membranes: The role of membrane biophysics on its therapeutic and toxic effects. Journal of Physical Chemistry B (Impact Factor 2012: 3.607). 2012
- Molecular interaction of Rifabutin on model lung surfactant monolayers. Journal of Physical Chemistry B (Impact Factor 2012: 3.607). 2012
- Resveratrol in medicinal chemistry: A critical review of its pharmacokinetics, drug-delivery, and membrane interactions. Current Medicinal Chemistry (Impact Factor 2012: 4.070). 2012
- S4(13)-PV cell-penetrating peptide induces physical and morphological changes in membrane-mimetic lipid systems and cell membranes: Implications for cell internalization. Biochimica et Biophysica Acta - Biomembranes (Impact Factor 2012: 3.389). 2012
- pH sensitive silica nanotubes as rationally designed vehicles for NSAIDs delivery. Colloids and Surfaces B: Biointerfaces (Impact Factor 2012: 3.554). 2012
- A reagent-free method based on a photo-induced fluorimetry in a sequential injection system. Talanta (Impact Factor 2011: 3.794). 2011
- Changes in PLA2 activity after interacting with anti-inflammatory drugs and model membranes: Evidence for the involvement of tryptophan residues. Chemistry and Physics of Lipids (Impact Factor 2011: 2.571). 2011
- Effects of non-steroidal anti-inflammatory drugs on the structure of lipid bilayers: Therapeutical aspects. Soft Matter (Impact Factor 2011: 4.390). 2011
- Interaction of carbonylcyanide p-trifluoromethoxyphenylhydrazone (FCCP) with lipid membrane systems: A biophysical approach with relevance to mitochondrial uncoupling. Journal of Bioenergetics and Biomembranes (Impact factor 2011: 2.813). 2011
- Lipid-drug interaction: Biophysical effects of tolmetin on membrane mimetic systems of different dimensionality. Journal of Physical Chemistry B (Impact Factor 2011: 3.696). 2011
- Liposomes as drug delivery systems for the treatment of TB. Nanomedicine (Impact Factor 2011: 5.055). 2011
- NSAIDs interactions with membranes: A biophysical approach. Langmuir (Impact Factor 2011: 4.186). 2011
- Nimesulide interaction with membrane model systems: Are membrane physical effects involved in nimesulide mitochondrial toxicity?. Toxicology in Vitro (Impact Factor 2011: 2.775). 2011
- Synchrotron SAXS and WAXS study of the interactions of NSAIDS with lipid membranes. Journal of Physical Chemistry B (Impact Factor 2011: 3.696). 2011
- A biophysical approach to phospholipase A2 activity and inhibition by anti-inflammatory drugs. Biophysical Chemistry (Impact Factor 2010: 2.108). 2010
- Drug-membrane interactions: Significance for medicinal chemistry. Current Medicinal Chemistry (Impact Factor 2010: 4.630). 2010
- Effects of resveratrol on membrane biophysical properties: Relevance for its pharmacological effects. Chemistry and Physics of Lipids (Impact Factor 2010: 2.861). 2010
- High-throughput microplate assay for the determination of drug partition coefficients. Nature Protocols (Impact Factpr 2010: 8.362). 2010
- Antioxidant activity of vitamin E and Trolox: Understanding of the factors that govern lipid peroxidation studies in Vitro. Food Biophysics (Impact Factor 2009: 1.371). 2009
- Automatic flow injection based methodologies for determination of scavenging capacity against biologically relevant reactive species of oxygen and nitrogen. Talanta (Impact Factor 2009: 3.290). 2009
- Effect of anti-inflammatory drugs in phosphatidylcholine membranes: A fluorescence and calorimetric study. Chemical Physics Letters (Impact Factor 2009: 2.291). 2009
- Sequential injection system for phospholipase A2 activity evaluation: Studies on liposomes using an environment-sensitive fluorescent probe. Talanta (Impact Factor 2009: 3.290). 2009
- Binding of nonsteroidal anti-inflammatory drugs to DPPC: Structure and thermodynamic aspects. Langmuir (Impact Factor 2008: 4.097). 2008
- Effect of nonsteroidal anti-inflammatory drugs on the cellular membrane fluidity. Journal of Pharmaceutical Sciences (Impact Factor 2008: 3.540). 2008
- Interactions of sulindac and its metabolites with phospholipid membranes: An explanation for the peroxidation protective effect of the bioactive metabolite. Free Radical Research. 2008
- Substituted phenols as pollutants that affect membrane fluidity. Journal of Environmental Biology (Impact Factor 2008: 1.359). 2008
- The conformation of fusogenic B18 peptide in surfactant solutions. Journal of Peptide Science (Impact Factor: 2008: 1.654). 2008
- Use of liposomes as membrane models to evaluate the contribution of drug-membrane interactions to antioxidant properties of etodolac. Redox Report (Impact Factor 2008: 2.013). 2008
- Use of liposomes to evaluate the role of membrane interactions on antioxidant activity. Analytica Chimica Acta (Impact Factor 2007: 3.186). 2007
- Interactions between oxicams and membrane bilayers: An explanation for their different COX selectivity. Medicinal Chemistry (Impact Factor 2.331). 2006
- Effect of anti-inflammatory drugs on splenocyte membrane fluidity. Analytical Biochemistry (Impact Fcator 2005: 2.670). 2005
- Effects of diclofenac on EPC liposome membrane properties. Analytical and Bioanalytical Chemistry (Impact Factor 2005: 2.591). 2005
- Interaction of clonixin with EPC liposomes used as membrane models. Journal of Pharmaceutical Sciences (Impact Factor 2005: 2.713). 2005
- Influence of some anti-inflammatory drugs in membrane fluidity studied by fluorescence anisotropy measurements. Physical Chemistry Chemical Physics (Impact Factor 2004: 2.093). 2004
- Partition and location of nimesulide in EPC liposomes: A spectrophotometric and fluorescence study. Analytical and Bioanalytical Chemistry (Impact Factor 2003: 3.328). 2003
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artigo de conferência
- A biophysical approach to formulation development: drug-plasma protein interaction 2018
- Biophysical approach to formulation development: drug-protein interaction 2018
- Role of liposomes as analytical tools to evaluate the antioxidant profile of pharmaceutical Drugs 2017
- Study of antioxidants effect at the air-water interface: a biophysical approach to membrane peroxidation 2012
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artigo de revista
- pH-Responsive Hybrid Nanoassemblies for Cancer Treatment: Formulation Development, Optimization, and In Vitro Therapeutic Performance. Pharmaceutics. 2023
- Omega-3- and Resveratrol-Loaded Lipid Nanosystems for Potential Use as Topical Formulations in Autoimmune, Inflammatory, and Cancerous Skin Diseases. Pharmaceutics. 2021
- A Biophysical Insight of Camptothecin Biodistribution: Towards a Molecular Understanding of Its Pharmacokinetic Issues. Pharmaceutics. 2021
- Electrospun fibers for vaginal administration of tenofovir disoproxil fumarate and emtricitabine in the context of topical pre-exposure prophylaxis. Journal of Control Release (Impact Factor: 7.940). 2021
- Avobenzone-loaded and omega-3-enriched lipid formulations for production of UV blocking sunscreen gels and textiles. Journal of Molecular Liquids. 2021
- Lipid Nanocarriers for Anti-HIV Therapeutics: A Focus on Physicochemical Properties and Biotechnological Advances. Pharmaceutics. 2021
- Novel amphiphilic chitosan micelles as carriers for hydrophobic anticancer drugs. Journal of Nanoparticle Research. 2020
- Polymeric Electrospun Fibrous Dressings for Topical Co-delivery of Acyclovir and Omega-3 Fatty Acids. Frontiers in Bioengineering and Biotechnology. 2019
- Rational Development of Liposomal Hydrogels: A Strategy for Topical Vaginal Antiretroviral Drug Delivery in the Context of HIV Prevention. Pharmaceutics. 2019
- Incorporation of lipid nanosystems containing omega-3 fatty acids and resveratrol in textile substrates for wound healing and anti-inflammatory applications. SN Applied Sciences. 2019
- Resveratrol-Loaded Lipid Nanocarriers Are Internalized By Endocytosis in Yeast. Journal of Natural Products. 2019
- A Systematic Review and Critical Analysis of the Role of Graphene-Based Nanomaterials in Cancer Theranostics. Pharmaceutics. 2018
- A Molecular Biophysical Approach to Diclofenac Topical Gastrointestinal Damage. International Journal of Molecular Sciences. 2018
- Lipid nanocarriers loaded with natural compounds: Potential new therapies for age related neurodegenerative diseases?. Elife. 2018
- Spectroscopic Studies as a Toolbox for Biophysical and Chemical Characterization of Lipid-Based Nanotherapeutics. Frontiers in Chemistry. 2018
- Role of counter-ion and helper lipid content in the design and properties of nanocarrier systems: a biophysical study in 2D and 3D lipid assemblies. Nanoscale. 2016
- Stealth monoolein-based nanocarriers for delivery of siRNA to cancer cells. Acta Biomaterialia. 2015
- Polymeric Versus Lipid Nanoparticles: Comparative Study of Nanoparticulate Systems as Indomethacin Carriers. Journal of Applied Solution Chemistry and Modeling. 2015
- Structural dynamics and physicochemical properties of pDNA/DODAB:MO lipoplexes : effect of pH and anionic lipids in inverted non-lamellar phases versus lamellar phases. Biochimica et Biophysica Acta (BBA). Biomembranes. 2014
- Tunable pDNA/DODAB: MO lipoplexes: The effect of incubation temperature on pDNA/DODAB: MO lipoplexes structure and transfection efficiency. Colloids and Surfaces B: Biointerfaces. 2014
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capítulo de livro
- Grapevine as a natural resource in the cosmetic industry 2024
- Bioactive lipids: Pharmaceutical, nutraceutical, and cosmeceutical applications 2023
- Bioactive lipids: pharmaceutical and nutraceutical applications 2022
- Co-delivery of anticancer drug and bioactive compound 2022
- Advances in Nanotheranostics with Plasmonic and Magnetic Nanoparticles 2021
- Graphene-based nanosystems: versatile nanotools for theranostics and bioremediation 2021
- Lipid-Based Nanocarriers for Co-Delivery of Anticancer Drugs and Natural Compounds 2021
- Nanomedicine and drug delivery approaches 2021
- Lipid-based colloidal carriers for topical application of antiviral drugs 2018
- A biophysical approach to the study of the therapeutic and toxic effects of non-steroidal anti-inflammatory drugs 2012
- Determination of the Scavenging Capacity Against Reactive Nitrogen Species by Automatic Flow Injection-Based Methodologies 2011
- Drug-Membrane Interactions: Molecular Mechanisms Underlying Therapeutic and Toxic Effects of Drugs 2010
- Use of Liposomes to Evaluate the Role of Membrane Interactions on Antioxidant Activity 2010
- Book review: quality in the analytical chemistry laboratory in quality in analytical measurements 1999
- Laboratory accreditation in different European Countries: Portugal in quality in analytical measurements 1999
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documento
- A photophysical approach to the development of nanotherapeutics 2023
- A photophysical approach to the development of nanotherapeutics. 2023
- Green graphene quantum dots for FRET based real-time pH-responsive drug release monitoring and imaging. 2023
- Physicochemical optimization of lipid-based nanocarriers for topical ophthalmic therapeutic delivery towards the posterior segment of the eye 2023
- Biophysical insights of an innovative lipid-engineered Stratum Corneum model for compound permeation studies 2023
- Biophysical insights of an innovative lipid-engineered Stratum Corneum model for compound permeation studies. 2023
- Design, optimization, and in vitro therapeutic performance of pH triggered doxorubicin from 2D and 3D lipid nanoassemblies 2023
- Incorporation of nanostructured lipid carriers containing quercetin and/or omega-3 in hydrogels for topical delivery 2023
- The valorization of macroalgae from the portuguese coast for the green synthesis of graphene quantum dots for pH-sensitive cancer theranostics 2023
- 2G4CANCER-Graphene/lipid nanosystems for cancer imaging and treatment. 2023
- 2G4CANCER - Graphene/lipid nanosystems for cancer imaging and treatment 2022
- A novel ceramide-based model as a platform to study compounds permeation through Stratum Corneum from a biophysical perspective 2022
- Development and characterization of nanostructured lipid carriers containing quercetin and/or omega-3 2022
- Hybrid nanosystems for cancer therapy 2022
- Label-free in situ monitoring of lipid bilayers formation and interaction with bioactive compounds 2022
- 2G4CANCER - Green graphene/lipid nanosystems for cancer imaging and treatment 2021
- Electrospun nanofibers loaded with Truvada® as a novel intravaginal delivery system for HIV prophylaxis 2021
- Membrane-water partitioning to screen drug candidates: towards a high-throughput microfluidic platform 2021
- Functional Lipid Nanosystems in Cancer 2021
- Novel Functional Chitosan Derivative Improves Intestinal Permeability of Camptothecin 2020
- Novel Chitosan Polymeric Micelles as a Delivery Vehicle of Hydrophobic Anticancer Drugs 2020
- Tenofovir disoproxil fumarate/emtricitabine-loaded electrospun fibers for topical pre-exposure prophylaxis of vaginal HIV transmission 2020
- Lipid colloidal dispersions loaded with omega-3 fatty acids and/or resveratrol developed for topical application against psoriasis (PA09) 2019
- Tenofovir disoproxil fumarate/emtricitabine-loaded electrospun fibers for vaginal administration and prevention of HIV transmission 2019
- The versatility of membrane-water partitioning in pharmacokinetic modelling 2019
- The membrane/aqueous partitioning as an essential tool for pharmacokinetic profiling to support drug design 2019
- Drug-biomembranes interaction studies and its relationship with potential biophysical membrane impairment 2019
- Nanographene oxide and lipid nanosystems as a cutting-edge strategy for cancer theranostic 2019
- Diclofenac¿s toxicity revisited with biomimetic models and biophysical studies 2019
- Lipid-based nanosystems loaded with curcumin as a promising strategy for cancer therapy 2019
- A biophysical insight of Camptothecin interaction with biomembrane models based in colloidal interfaces 2019
- Novel chitosan derivative to produce polymeric micelles as vehicle for delivery of anticancer drugs 2019
- Lipid-based colloidal biomimetic interfaces as a promising approach for drug-biomembranes interaction evaluation 2019
- Nanographene oxide and lipid nanosystems as a cutting-edge strategy for cancer theranostics 2019
- Pre-formulation studies for rational development of lipid colloidal carriers containing resveratrol 2019
- Hydrogels carrying lipid nanosystems as a prophylactic approach towards HIV 2019
- Biophysical Characterization of drug-biomembrane model interactions: Redefining the drug screening process 2019
- Biophysical toolbox to predict curcumin-biointerfaces and curcumin-nanocarrier interactions 2019
- Chitosan modifications into new amphiphilic derivatives for polymeric micelles production as drug delivery systems 2019
- Diclofenac's toxicity revisited with biomimetic models and biophysical studies 2019
- Diclofenac: topical gastrointestinal damage revisited with biomimetic models and biophysical studies 2019
- Drug-biomembranes interaction studies and its relationship with potential biophysical membrane impairment, 2019
- Lipid colloidal dispersions loaded with omega-3 fatty acids and/or resveratrol developed for topical application against psoriasis 2019
- Liposomal Curcumin to overcome multidrug resistance in Cancer Treatment 2019
- Liposomal hydrogels for the intravaginal co-delivery of antiretroviral drugs 2019
- Topical formulation containing omega-3 and/or Resveratol encapsulated in lipid colloidal dispersions for psoriasis 2019
- Challenges on the development of nanotherapeutics: biophysical studies to guide formulation development 2018
- Biophysical toolbox for nanotherapeutics characterization 2018
- Lipid-based Nanocarriers for Antiretroviral Drug Delivery: a HIV Topical Prevention Strategy. AIDS Research and Human Retroviruses. 2018
- Lipid-based Nanocarriers for Antiretroviral Drug Delivery: an HIV Topical Prevention Strategy. 2018
- Novel Strategies for cancer treatment: drug delivery combining graphene oxide quantum dots and core-filled lipid vesicles 2017
- Local delivery of doxorubicin nanocrystals from electrospun nanofibers 2017
- Co-delivery of two anti-HIV drug nanocrystals from electrospun nanofibers 2017
- Control release of acyclovir nanocrystals from electrospun nanofibers: comparison of two polymeric matrices 2017
- Development of an effective PCL/PEG nanoparticle-based system to deliver a potent MAO-B chromone–based inhibitor across blood-brain barrier 2017
- Release of acyclovir from polymeric nanofibers: comparing aqueous versus membrane-water interfaces kinetics 2017
- Smart drug delivery systems for cancer therapy 2017
- Spectroscopic Studies as a Biophysical Toolbox for Pharmacokinetic Drug Profiling 2016
- Biophysical Characterization of Drug–Lipid Interactions for the design of smart drug delivery systems 2016
- Biophysical characterization, nanoscale composition and cell uptake studies of pH-sensitive drug delivery systems 2016
- Characterization of Smart Drug Delivery Systems 2016
- Development of a lipid based nanoformulation for delivery of acyclovir 2016
- Paclitaxel pharmaceutical profiling aiming the optimization of a novel lipid nanotherapy 2016
- The ‘nanotherapy’ revolution: three different aplications of lipid nanosystems in therapeutics 2016
- Biophysical screening of safety and efficiency of Paclitaxel encapsulated in fully filled membranar nanoparticles 2015
- Development and characterization of DODAB:MO (1:2) liposomes encapsulating Bovine Serum Albumine (BSA) for targeted drug delivery 2015
- Profiling pharmacokinetic parameters of resveratrol-liposomal formulations for nanotherapy purposes 2015
- Bovine serum albumin (BSA) encapsulated in DODAB-MO (1:2) liposomes for targeted drug delivery: development and characterization 2014
- Development of a liposomal formulation for the delivery of an anticancer drug 2014
- Effect of the counter-ion on DODAX:MO siRNA-lipoplexes gene silencing efficiency 2014
- Effect of the counter-ion on DODAX:MO siRNA-lipoplexes gene silencing efficiency, Effect of the counter-ion on DODAX:MO siRNA-lipoplexes gene silencing efficiency 2014
- Fluorescence quenching and anisotropy studies as a toolbox for pharmacokinetic evaluation of drug-delivery systems 2014
- Nanocarrier systems for delivery of chemopreventive phenolic compounds 2014
- Optimization of DODAX/MO-Based Vectors for cancer treatment 2014
- Paclitaxel encapsulation in DODAC:MO liposomes for pharmacokinetic profile improvement 2014
- Tuning lipid membrane composition towards less toxic and more efficient lipoplexes: the effect of DC-Cholesterol and MO on DODAX lipid systems 2014
- A biophysical study on the interaction of S4(13)-PV cell penetrating peptide with model lipid membranes 2011
- Anti-inflammatory activities of chiral xanthones-activity and inhibition of bee venom phospholipase A2 and ovine COX-1 and human recombinant COX-2 2011
- Biomimetic membranes applied to the study of drug-membrane interactions: the case of celecoxib 2011
- Biophysical interactions of diclofenac with phospholipids bilayers: implications in mitochondrial toxicity 2011
- Biophysical interactions of rifabutin with phosphatidylcholine (DPPC) monolayers 2011
- Biophysical studies of the interactions between NSAIDs and membranes: insights on their modes of action 2011
- Comparison among of biomimetic lipid aggregates as in vitro models to assess antioxidant capacity against peroxidation 2011
- Development of novel drug delivery systems based on lipid nanoparticles 2011
- Encapsulation of lornoxicam in polymeric nanoparticles 2011
- In vitro assessment of meloxicam effects on biomembranes 2011
- In vitro evaluation of the pharmacokinetics of nimesculide and meloxicam 2011
- Interactions of diclofenac with phospholipid bilayers: effects on membrane biophysics and nanoscale lipid membrane organization. 2011
- Lipid monolayers as resourceful tools to study the activity of enzymes and drugs at the interface 2011
- Lipid nanoparticles for topical and transdermal application for cellulite treatment 2011
- Lipid-drug interaction: biophysical and structural effects of Celecoxib on membrane mimetic systems 2011
- Liposomes as membrane models: biophysical interactions with rifabutin 2011
- Membrane biophysical studies as a tool to understand the mechanism of action of antitubercular drugs 2011
- NSAIDs interactions with membranes: a biophysical approach 2011
- Synthesis of lipid nanoparticles for applications in the development of novel drug delivery systems 2011
- Understanding the therapeutic and toxic mechanisms of action of non-steroidal anti-inflammatory drugs through the use of biomimetic models 2011
- A reagent-free method based on photo-induced fluorimetry in a sequential injection system 2010
- Activity and inhibition of bee venom phospholipase A2 studied by fluorescent methodologies 2010
- Determining drug-serum protein binding interaction 2010
- Development of novel lipid nanoparticles to encapsulate resveratrol for further preparation of a nutraceutical 2010
- Drug-membrane interaction studies applied to a newly synthesized rifabutin derivative 2010
- Effect of antibercular drugs on membrane biophysics: implications for drugs mode of action 2010
- Evaluation of toxicological effects of drugs on the prospects of membrane biophysics 2010
- Interaction mechanism of clonixin and lornoxicam with human serum albumin 2010
- Interaction of flunixin and dipyrone with human serum albumin: fluorescence studies 2010
- Interaction of resveratrol with model membranes 2010
- Methodologies for evaluation of peroxyl radical scavenging activity in hydrophobic or hydrophilic conditions using biometric systems 2010
- Microplate fluorimetric methodologies to assess antioxidant activity at different locations on phospholipid membranes 2010
- Perturbing effects of piroxicam on a model membrane system: role in its chemopreventive function 2010
- Phospholipase A2 as a control point in the diversity of lipid mediators 2010
- Preparation and characterization of PLGA nanoparticles containing a non-steroidal anti-inflammatory agent 2010
- Preparation and characterization of solid lipid nanoparticles (SLN) applied to deliver resveratrol in beverages 2010
- The interaction of celecoxib with membranares: a biophysical study 2010
- The role of drug-membrane interactions in the cardiovascular effects of b-blockers 2010
- Development and validation of an improved oxygen radical absorbance capacity assay using biomimetic systems 2009
- Drug release studies on functionalized sílica nanotubes 2009
- Influence of NSAIDs on the activity of enzymes at interfaces 2009
- Magnetic nanotubes and nanowires in porous alumina membranes for biomedical applications 2009
- Membrane biophysical studies for evaluations of toxicological effects of pharmaceutical compounds 2009
- Ordered assembly of oxide nanotubes in porous alumina membranes for biomedical applications 2009
- Perturbations on the biophysical properties of membranes revealed by fluorescence steady-state and lifetime studies 2009
- Studies for improving therapeutic effects of drugs: the role of membrane biophysics and drug-membrane interactions. 2009
- Biophysical changes on membranes after NSAIDs contact 2008
- Development of an automatic methodology for the assessment of the anti-inflammatory drugs’ inhibitory effect on phospholipase A2 2008
- Drug-membrane interactions enhance the scavenging activity against reactive oxygen species 2008
- Evaluation of the interaction of ibuprofen and indomethacin with membrane models 2008
- Importance of drug-membrane interaction studies for the rational development of therapeutic applications 2008
- Interaction of NSAIDS with DMPC liposomes: studies of partition, location and membrane fluidity 2008
- Interactions between NSAIDS and membrane bilayers: an explanation for their different mode of action 2008
- Membrane biophysics modification promoted by NSAID 2008
- Molecular mechanisms underlying therapeutic and toxic effects of anti-inflammatory drugs 2008
- Perturbing effects of b-blockers on a model membrane system: role of lipophilicity and chemical structure 2008
- Phospholipase A2, NSAIDs and lipid interactions 2008
- Silica nanotubes as drug delivery systems: tuning the surface functionalization for an efficient drug release 2008
- Study of activity and inhibition of phospholipase A2 by the action of meloxicam 2008
- Surface modification of silica nanotubes for efficient drug release 2008
- The role of membrane interactions to evaluate the antioxidant profile of pharmaceutical drugs 2008
- Evaluation of the effect of phenolic compounds on cell membrane fluidity 2007
- Evaluation of the effect of some non-steroidal anti-inflammatory drugs on cell membrane fluidity 2007
- Fluorescence studies of the biophysical interaction of a fusogenic peptide with membrane model systems 2007
- Implementation of a methodology for evaluation of phospholipase activity 2007
- Role of liposomes as analytical tools to evaluate the antioxidant profile of pharmaceutical drugs 2007
- Study of the chemical interaction of drugs with membrane phospholipids and its influence on the structural lipidic organization 2007
- Use of biomimetic models in the evaluation of the interaction of oxaprozim, sulindac and sulindac sulphide with biological membranes 2007
- Evaluation of NSAIDs antioxidant activity in a liposomal model system 2006
- Interaction of nonsteroidal anti-inflammatory drugs (NSAIDs) with gastric surface active phospholipids: a possible mechanism for the gastric toxicity 2006
- Effect of non-steroidal anti-inflammatories on lipid peroxidation induced by hydroxyl radicals 2005
- Evaluation of the antioxidant capacity of non-steroidal anti-inflammatory drugs in membrane models 2005
- Interaction of non-steroidal anti-inflammatory drugs (NSAIDS) with large unilamellar liposomes: application of fluorescence methodologies 2005
- On the importance of drug-membrane interactions: A study of non steroidal anti-inflammatory drugs with liposomes as biological membrane models 2005
- Relationship between the ability of NSAIDS to alter the membrane fluidity and their antioxidant activity 2005
- Utilização de modelos membranares na avaliação da actividade de fármacos 2005
- Interaction of oxicams with EPC liposomes used as membrane models 2004
- Liposomes as biological membrane models aiming a better understanding of the mode of action of non-steroidal anti-inflammatory drugs 2004
- NSAIDs’antioxidant activity: any influence in therapeutic and toxic effects? 2004
- Oxicams inhibit oxidative damage in membrane models: scavenging oxyradicals or changing membrane fluidity? 2004
- Studies of sulindac induced perturbations inn membrane models aiming a better understanding of therapeutical and toxic effects 2004
- Effect of anti-inflammatory drugs in membrane fluidity in the presence of free radicals 2003
- Evaluation of the location of non-steroidal anti-inflammatories in liposomes by fluorescence inactivation studies 2003
- Evaluation of the partition coefficient of non-steroidal anti-inflammatory drugs in hexadeciphosphocholine micelles by derivative spectrophotometry 2003
- Fluidity/peroxidation relationship using liposomes as membrane models 2003
- Influence of anti-inflammatory drugs in membrane fluidity studied by fluorescence anisotropy measurements 2003
- Quantifying the maximum membrane uptake of drugs by measuring zeta-potentials 2003
- Study of membrane alterations caused by sulindac and its metabolites 2003
- Spectroscopic determination of the participation coefficient of non-steroidal anti-inflammatory drugs in liposomes 2001
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