publicações selecionadas
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artigo académico
- Exploiting the Antiparasitic Activity of Naphthalimides Derivatives. Int. J. Chem. Pharm. Sci. 2016
- Novel pyridine-2,4,6-tricarbohydrazide derivatives: Design, synthesis, characterization and in vitro biological evaluation as a- and ß-glucosidase inhibitors. Bioorganic Chemistry. 2014
- Synthesis and evaluation of a-, ß-glucosidase inhibition of 1-N-carboxamide-1-azafagomines and 5-epi-1-azafagomines. Carbohydrate Research. 2014
- Synthesis of Iminosugars from Tetroses. Curr. Org. Synth.. 2014
- STUDY BASED ON ELECTRONIC DESCRIPTORS OF THE DIASTEREOSELECTIVE AZA-DIELS-ALDER CYCLOADDITION OF [(1R)-10-(N,N-DIETHYLSULFAMOYL)ISOBORNYL] 2H-AZIRINE-3-CARBOXYLATE TO E,E-1,4-DIACETOXY-1,3-BUTADIENE. Journal of the Chilean Chemical SocIETy. 2013
- Asymmetric Diels-Alder cycloadditions of d-erythrose 1,3-butadienes to achiral t-butyl 2H-azirine 3-carboxylate. Tetrahedron Asymmetry. 2013
- Highly stereoselective cycloadditions of Danishefsky's diene to (-)-8-phenylmenthyl and (+)-8-phenylneomenthyl glyoxylate N-phenylethylimines. Tetrahedron. 2013
- Diastereo-controlled DielsAlder cycloadditions of erythrose benzylidene-acetal 1,3-butadienes by 4-substituted-1,2,4-triazoline-3,5-dione: Evidence for the stereoelectronic effects on the dienes. Tetrahedron Asymmetry. 2010
- Diastereoselective Diels-Alder cycloaddition of [(1R)-10-(N,N-diethylsulfamoyl)isobornyl] 2H-azirine to nucleophilic 1,4-disubstituted 1,3-dienes. Tetrahedron Asymmetry. 2009
- Ethyl 2-(diisopropoxyphosphoryl)-2h-azirine-3-carboxylate: Reactions with nucleophilic 1,3-dienes. Synthesis. 2009
- Synthesis of polyhydroxylated pyrrolidines and aziridinopyrrolidines from [4p+2p] cycloadducts of cyclopentadiene and imines/2H-azirines. Synthesis. 2008
- A new approach to the synthesis of N,N-dialkyladenine derivatives. European Journal of Organic Chemistry. 2007
- Formation of pyridin-4(1H)-one versus 1H-azepin-4(7H)-one by treatment of 4-tert-butyldimethylsilyloxy-2-amino-1-aza-bicyclo[4.1.0]hept-3-enes with tetrabutylammonium fluoride. Tetrahedron. 2007
- Regio- and stereo-selective aza-Diels-Alder reaction of ethyl glyoxylate 4-methoxyphenylimine with 1,3-dienes in the presence of BF3·Et2O. Evidence for a non-concerted mechanism. Tetrahedron. 2007
- Diels-Alder cycloaddition of electrophilic 2H-azirines with 3-(3-(tert-butyldimethylsilyloxy)buta-1,3-dienyl)oxazolidin-2-ones. Treatment of the cycloadducts under acidic conditions. Tetrahedron. 2006
- Stereoselective synthesis of polyhydroxylated pyrrolidines: a route to novel 3,5-bis(hydroxymethyl)pyrrolidines from 2-azabicyclo[2.2.1]hept-5-enes. Tetrahedron Letters. 2006
- Intermolecular alkyl radical addition to methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxylate. Synlett. 2003
- Stereoselective Cycloaddition of 1-Glucosyl-1,3-butadienes with t-Butyl 2H-Azirine-3-carboxylate, Glyoxylates and Imines. Tetrahedron Letters. 2003
- Diastereoselective synthesis of aziridines from (1R)-10-(N,N-dialkylsulfamoyl)isobornyl 2H-azirine-3-carboxylates. Journal of the Chemical SocIETy-Perkin Transactions 1. 2002
- Diels-Alder reactions of alkyl 2H-azirine-3-carboxylates with furans. Journal of the Chemical SocIETy-Perkin Transactions 1. 2001
- Novel aziridine esters by the addition of aromatic nitrogen heterocycles to a 2H-azirine-3-carboxylic ester. Tetrahedron Letters. 2000
- Reactivity studies of ethyl(Z)-N-(2-amino-1,2-dicyanovinyl) formimidate with carbonyl compounds in the presence of base. Journal of Heterocyclic Chemistry. 2000
- Diastereoselectivity in the addition and cycloaddition reactions of a chiral ester of 2H-azirine-3-carboxylic acid. Journal of the Chemical SocIETy-Perkin Transactions 1. 1999
- Reactions of methyl 2-aryl-2H-azirine-3-carboxylates with nucleophiles. Journal of the Chemical SocIETy-Perkin Transactions 1. 1999
- Synthesis and mechanism of formation of novel 2,5-dihydro-2,5-diimino- 3,4-di[(n,n-dimethylamino)methylideneamino]pyrroles and 5-amino-3,4-di[(n,n- dimethylamino)methylideneamino]2h-2-iminopyrroles. Journal of Heterocyclic Chemistry. 1999
- Generation and diels-alder reactions of t-butyl 2H-azirine-3-carboxylate. Tetrahedron Letters. 1998
- Methyl 2-aryl-2H-azirine-3-carboxylates as dienophiles. Journal of the Chemical SocIETy-Perkin Transactions 1. 1998
- Synthesis of 6-Cyanopurines and the Isolation and X-ray Structure of Novel 2H-Pyrroles. Journal of Heterocyclic Chemistry. 1997
- X-Ray Structure of 4-[5-Amino-1-(4-tolyl)-1H-imidazol-4-yl]-5-imino-2,2-dimethyl-2,5-dihydrooxazole and the Synthesis of a Related N3-Acetyl Analogue. Journal of Chemical Research - Part S. 1996
- A Tautomeric Pair of 2,2-Dimethyl-6-carbamoyl-9-phenyl-dihydropurine. Acta Crystallographica Section C-Crystal Structure Communications. 1995
- Synthesis of 4- and 5-disubstituted 1-benzylimidazoles, important precursors of purine analogs. Journal of Heterocyclic Chemistry. 1994
- Synthesis of 4-substituted 8-amino-4,5-dihydro-3H-pyrrolo[3,4-f]-1,3,5- triazepin-6-ones and 5-amino-2-aryl-4-(1-aryl-5-alkylideneaminoimidazol-4-yl)-1, 3-oxazoles. Journal of the Chemical SocIETy-Perkin Transactions 1. 1994
- Synthesis of 9-aryl-6-carbamoyl-1,2-dihydropurines and a study of their tautomerism. Journal of the Chemical SocIETy, Perkin Transactions 2. 1994
- Novel 4-substituted 4,5-dihydro-3H-(8-amino-6-oxo)pyrrolo[3,4-f][1,3,5] triazepines from(Z)-N2-(2-amino-1,2-dicyano)formamidine and carbonyl compounds. Journal of the Chemical Society, Chemical Communications. 1993
- (Z)-N3-(2-Amino-1,2-dicyanovinyl)formamidrazone: A precursor in the synthesis of 1,5-diaminoimidazoles and 6-carbamoyl-1,2-dihydropurines. Journal of the Chemical SocIETy-Perkin Transactions 1. 1992
- Synthesis of 5-amino-4-(cyanoformimidoyl)-1H-imidazole: A reactive intermediate for the synthesis of 6-carbamoyl-1,2-dihydropurines and 6-carbamoylpurines. Journal of the Chemical SocIETy-Perkin Transactions 1. 1990
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artigo de revista
- Synthesis and Bioactivity of New Analogue of Bicyclic 1-Azafagomine. Chemistryselect. 2019
- A Short Synthesis of (2S,3S,4R)-Dihydroxyhomoprolines from d-Erythrose-Derived 5,6-Dihydro-2H-pyran-2-one. Synthesis. 2019
- (3S,4R)-3,4-Dihydroxy-N-alkyl-l-homoprolines: synthesis and computational mechanistic studies. Organic and Biomolecular Chemistry. 2019
- Total Stereoselective Michael Addition of N- and S- Nucleophiles to a d-Erythrosyl 1,5-Lactone Derivative. Experimental and Theoretical Studies Devoted to the Synthesis of 2,6-Dideoxy-4-functionalized-d-ribono-hexono-1,4-lactone. Journal of Organic Chemistry. 2018
- Molecular docking and glucosidase inhibition studies of novel N-arylthiazole-2-amines and Ethyl 2-[aryl(thiazol-2-yl)amino]acetates. Medicinal Chemistry Research. 2017
- Total Facial Discrimination of 1,3-Dipolar Cycloadditions in a d-Erythrose 1,3-Dioxane Template: Computational Studies of a Concerted Mechanism. Journal of Organic Chemistry. 2017
- Styrene Epoxidation Over Heterogeneous Manganese(III) Complexes. Archives of Metallurgy and Materials. 2016
- Total Facial Selectivity of a D-Erythrosyl Aromatic Imine in [4p+2p] Cycloadditions; Synthesis of 2-Alkylpolyol 1,2,3,4-Tetrahydroquinolines. Organic and Biomolecular Chemistry. 2016
- Evaluation of New Naphthalimides as Potential Anticancer Agents against Breast Cancer MCF-7, Pancreatic Cancer BxPC-3 and Colon Cancer HCT- 15 Cell Lines. Organic Chemistry: Current Research. 2015
- Norbornene Oxidation by Chiral Complexes Encapsulated in NaY Zeolite. Journal of Physical Chemistry C. 2014
- Enantioselective Diels-Alder Cycloadditions in the Synthesis of Two Enantiomeric Sets of Chiral Polihydroxylated Pipecolic Acid Derivatives. Synlett. 2014
- Diastereoselectivity in diels-alder cycloadditions of erythrose benzylidene-acetal 1,3-butadienes with maleimides. Synlett. 2012
- Diels-alder cycloaddition in the synthesis of 1-azafagomine, analogs, and derivatives as glycosidase inhibitors. Mini-Reviews in Medicinal Chemistry. 2012
- Advances in the synthesis of homochiral (-)-1-azafagomine and (+)-5-epi-1-azafagomine. 1-N-phenyl carboxamide derivatives of both enantiomers of 1-azafagomine: Leads for the synthesis of active a-glycosidase inhibitors.. Journal of Organic Chemistry. 2011
- Highly diastereoselective synthesis of 2-azabicyclo[2.2.1]hept-5-ene derivatives: Bronsted acid catalyzed aza-Diels-Alder reaction between cyclopentadiene and imino-acetates with two chiral auxiliaries. Tetrahedron. 2011
- Ethyl 3-(2-pyridyl)-2H-azirine-2-carboxylate: Synthesis and reaction with dienes. Synthesis. 2005
- Synthesis of 1,3,8,8a-tetrahydro-3,8-epoxyazirino[1,2-b]isoquinolines and their reactions with oxygen nucleophiles. Heterocycles. 2005
- Diels-Alder cycloaddition of 2-azadienes to methyl 2-(2,6-dichlorophenyl)- 2H-azirine-3-carboxylate in the synthesis of methyl 4-oxo-1,3-diazabicyclo[4.1. 0]heptane-6-carboxylates. Tetrahedron. 2004
- Cycloaddition of methyl 2-(2,6-dichorophenyl)-2H-azirine-3-carboxylate to electron-rich 2-azadienes. Tetrahedron Letters. 2003
- Optically active aziridine esters by nucleophilic addition of nitrogen heterocycles to a chiral 2H-azirine-2-carboxylic ester. Tetrahedron Letters. 2003