Publicações no PortAberta

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Agostinho Albérico Rodrigues de Carvalho

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publicações selecionadas

artigo académico
- Deregulated immune cell recruitment orchestrated by c-MET impairs pulmonary inflammation and fibrosis. Respiratory Research. 2024
- Humoral pathways of innate immune regulation in granuloma formation. Trends in Immunology. 2024
- Integrating genetic and immune factors to uncover pathogenetic mechanisms of viral-associated pulmonary aspergillosis. Mbio. 2024
- Novel antifungals and treatment approaches to tackle resistance and improve outcomes of invasive fungal disease. Clinical Microbiology Reviews. 2024
- Akkermansia muciniphila and Parabacteroides distasonis synergistically protect from colitis by promoting ILC3 in the gut. Mbio. 2024
- Metabolic regulation of the host–fungus interaction: from biological principles to therapeutic opportunities. Journal of Leukocyte Biology. 2024
- Metabolic regulation of the host-fungus interaction: from biological principles to therapeutic opportunities. Journal of Leukocyte Biology. 2024
- Circulatory Inflammatory Proteins as Early Diagnostic Biomarkers for Invasive Aspergillosis in Patients with Hematologic Malignancies—an Exploratory Study. Mycopathologia. 2024
- Lower respiratory tract single-cell RNA sequencing and neutrophil extracellular trap profiling of COVID-19-associated pulmonary aspergillosis: a single centre, retrospective, observational study. The Lancet Microbe. 2024
- MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study. The Lancet Neurology. 2024
- Multicentric Study on the Clinical Mycology Capacity and Access to Antifungal Treatment in Portugal. Mycopathologia. 2024
- Intramacrophage lipid accumulation compromises T cell responses and is associated with impaired drug therapy against visceral leishmaniasis. Immunology. 2023
- Development of a Versatile Toolbox for Genetic Manipulation of Sporothrix brasiliensis. Microbiology Spectrum. 2023
- Glutamine Metabolism Supports the Functional Activity of Immune Cells against Aspergillus fumigatus. Microbiology Spectrum. 2023
- A signature of differential gene expression in bronchoalveolar lavage fluid predicts mortality in influenza-associated pulmonary aspergillosis. Intensive Care Medicine. 2023
- Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway. Cell Host & Microbe. 2023
- Global consortium for the classification of fungi and fungus-like taxa. Mycosphere. 2023
- PTX3 Inhibits Complement-Driven Macrophage Activation to Restrain Granuloma Formation in Sarcoidosis.. American Journal of Respiratory and Critical Care Medicine. 2022
- Hypoxia inducible-factor 1 alpha regulates neutrophil recruitment during fungal-elicited granulomatous inflammation. Frontiers in Cellular and Infection Microbiology. 2022
- Genetic determinants of fungi-induced ROS production are associated with the risk of invasive pulmonary aspergillosis. Redox Biology. 2022
- COVID-19-associated fungal infections. Nature Microbiology. 2022
- Lung epithelial and myeloid innate immunity in influenza-associated or COVID-19-associated pulmonary aspergillosis: an observational study. Lancet Respiratory Medicine. 2022
- IL-10 Overexpression After BCG Vaccination Does Not Impair Control of Mycobacterium tuberculosis Infection.. Frontiers in Immunology. 2022
- MAVS Expression in Alveolar Macrophages Is Essential for Host Resistance against Aspergillus fumigatus. Journal of Immunology. 2022
- Let's talk about sex characteristics: As a risk factor for invasive fungal diseases. Mycoses. 2022
- Understanding the genetic basis of immune responses to fungal infection. Expert Review of Anti-Infective Therapy. 2022
- Regulation of gliotoxin biosynthesis and protection in Aspergillus species 2022
- Lung microbiota predict invasive pulmonary aspergillosis and its outcome in immunocompromised patients. Thorax. 2022
- Targeting immunometabolism in host-directed therapies to fungal disease. Clinical and Experimental Immunology. 2022
- The emergence of COVID-19 associated mucormycosis: a review of cases from 18 countries. The Lancet Microbe. 2022
- Dysregulation of glycerophospholipid metabolism during Behçet's disease contributes to a pro-inflammatory phenotype of circulating monocytes. Emerging Microbes & Infections. 2021
- Early IL-10 promotes vasculature associated CD4+ T cells unable to control Mycobacterium tuberculosis infection. JCI Insight. 2021
- Neuraminidase and SIGLEC15 modulate the host defense against pulmonary aspergillosis. Cell Reports Medicine. 2021
- A High Rate of Recurrent Vulvovaginal Candidiasis and Therapeutic Failure of Azole Derivatives Among Iranian Women. Antibiotics. 2021
- Aspergillus fumigatus Acetate Utilization Impacts Virulence Traits and Pathogenicity. Mbio. 2021
- Aspergillus fumigatus and aspergillosis: From basics to clinics. Studies in Mycology. 2021
- Comparative host transcriptome in response to pathogenic fungi identifies common and species-specific transcriptional antifungal host response pathways. Computational and Structural Biotechnology Journal. 2021
- Current Challenges for IDO2 as Target in Cancer Immunotherapy. Frontiers in Immunology. 2021
- Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response. PLoS Biology. 2021
- Genetic Variation in PFKFB3 Impairs Antifungal Immunometabolic Responses and Predisposes to Invasive Pulmonary Aspergillosis. Mbio. 2021
- Paracoccin Overexpression in Paracoccidioides brasiliensis Enhances Fungal Virulence by Remodeling Chitin Properties of the Cell Wall. Journal of Infectious Diseases. 2021
- Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus. Nature Communications. 2021
- TREM1 regulates antifungal immune responses in invasive pulmonary aspergillosis. Virulence. 2021
- The potential role for topical imiquimod in the treatment of chronic mucocutaneous candidiasis caused by gain-of-function mutation in STAT1: A case-report. Dermatologic Therapy. 2021
- Proteome analysis of bronchoalveolar lavage fluids reveals host and fungal proteins highly expressed during invasive pulmonary aspergillosis in mice and humans. Virulence. 2020
- Reply to Han et al.: On track for an IDO1-based personalized therapy in autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 2020
- Microbiota-derived metabolites as diagnostic markers for respiratory fungal infections. Journal of Pharmaceutical and Biomedical Analysis. 2020
- Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity. Nature Communications. 2020
- Editorial: Host and Pathogen Determinants of Allergic and Invasive Fungal Diseases. Frontiers in Immunology. 2020
- Glutamine supplementation improves the efficacy of miltefosine treatment for visceral leishmaniasis. PLoS Neglected Tropical Diseases. 2020
- The Absence of HIF-1a Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis. Cell Reports. 2020
- Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation. Proceedings of the National Academy of Sciences of the United States of America. 2020
- Aspergillus fumigatus DHN-Melanin. Current Topics in Microbiology and Immunology. 2020
- Editorial overview: Emerging topics in host-fungus interactions. Current Opinion in Microbiology. 2020
- Flotillin-Dependent Membrane Microdomains Are Required for Functional Phagolysosomes against Fungal Infections. Cell Reports. 2020
- Host immune genetic variations influence the risk of developing acute myeloid leukaemia: results from the NuCLEAR consortium. Blood Cancer Journal. 2020
- Polymorphisms within the ARNT2 and CX3CR1 Genes Are Associated with the Risk of Developing Invasive Aspergillosis. Infection and Immunity. 2020
- The Portuguese Society for Immunology (SPI): history and mission. European Journal of Immunology. 2020
- Host Genetic Signatures of Susceptibility to Fungal Disease. Current Topics in Microbiology and Immunology. 2019
- High-resolution melting assay for genotyping variants of the CYP2C19 enzyme and predicting voriconazole effectiveness. Antimicrobial Agents and Chemotherapy. 2019
- Host Genetics Takes a Toll on Immunity to Cryptococcus. EBioMedicine. 2018
- Toward the Identification of a Genetic Risk Signature for Pulmonary Aspergillosis in Chronic Obstructive Pulmonary Disease. Clinical Infectious Diseases. 2018
- Editorial: An omics perspective on fungal infection: Toward next-generation diagnosis and therapy. Antibiotics. 2017
- Host-Derived Biomarkers for Risk Assessment of Invasive Fungal Diseases. Methods in Molecular Biology. 2017
- IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity. Journal of Allergy and Clinical Immunology. 2017
- Association of a variable number tandem repeat in the NLRP3 gene in women with susceptibility to RVVC. European Journal of Clinical Microbiology & Infectious Diseases. 2016
- PTX3-Based Genetic Testing for Risk of Aspergillosis after Lung Transplant. Clinical Infectious Diseases. 2015
- PTX3 Deficiency and Aspergillosis. New England Journal of Medicine. 2014
- PTX3 binds MD-2 and promotes TRIF-dependent immune protection in aspergillosis. Journal of Immunology. 2014
- Characterization of Specific Immune Responses to Different Aspergillus Antigens during the Course of Invasive Aspergillosis in Hematologic Patients. Antibiotics. 2013
- Human Genetic Susceptibility to Invasive Aspergillosis. PLoS Pathogens. 2013
- Hypoxia Promotes Danger-mediated Inflammation via Receptor for Advanced Glycation End Products in Cystic Fibrosis. American Journal of Respiratory and Critical Care Medicine. 2013
- IL-22 and IDO1 Affect Immunity and Tolerance to Murine and Human Vaginal Candidiasis. PLoS Pathogens. 2013
- Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22. Immunity. 2013
- Host genetics and invasive fungal diseases: Towards improved diagnosis and therapy?. Expert Review of Anti-Infective Therapy. 2012
- Inflammation in aspergillosis: The good, the bad, and the therapeutic. Annals of the New York Academy of Sciences. 2012
- Genetic variability of innate immunity impacts human susceptibility to fungal diseases. International Journal of Infectious Diseases. 2010
- Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis. Mucosal Immunology. 2010
- Prognostic significance of genetic variants in the IL-23/Th17 pathway for the outcome of T cell-depleted allogeneic stem cell transplantation. Bone Marrow Transplantation. 2010
artigo de revista
- Echinacea purpurea Fractions Represent Promising Plant-Based Anti-Inflammatory Formulations. Antioxidants. 2023
- Erythrocyte-derived liposomes for the treatment of inflammatory diseases. Journal of Drug Targeting. 2022
- Functional Genetic Variants in ATG10 Are Associated with Acute Myeloid Leukemia. Cancers. 2021
- Biofunctionalized Liposomes to Monitor Rheumatoid Arthritis Regression Stimulated by Interleukin-23 Neutralization. Advanced Healthcare Materials. 2021
- Polymorphisms within the TNFSF4 and MAPKAPK2 loci influence the risk of developing invasive aspergillosis: A two-stage case control study in the context of the aspBIOmics consortium. Journal of Fungi. 2021
- COVID-19-Associated Candidiasis (CAC): An Underestimated Complication in the Absence of Immunological Predispositions?. Journal of Fungi. 2020
- COVID-19 Associated Pulmonary Aspergillosis (CAPA): From Immunology to Treatment. Journal of Fungi. 2020
- Mothers' distress exposure and children's withdrawn behavior – A moderating role for the Interferon Gamma gene (IFNG). Developmental Psychobiology. 2020
- Biofunctional Nanofibrous Substrate for Local TNF-Capturing as a Strategy to Control Inflammation in Arthritic Joints. Nanomaterials. 2019
- Ploidy Determination in the Pathogenic Fungus Sporothrix spp.. Antibiotics. 2019
- Amino acid metabolism as drug target in autoimmune diseases. Autoimmunity Reviews. 2019
- Genetic Regulation of the Host-Fungus Interaction in the Pathogenesis of Aspergillosis. Current Fungal Infection Reports. 2019
- Genetic defects in fungal recognition and susceptibility to invasive pulmonary aspergillosis. Blood. 2019
- Immune parameters for diagnosis and treatment monitoring in invasive mold infection. Journal of Fungi. 2019
- PTX3 Polymorphisms Influence Cytomegalovirus Reactivation After Stem-Cell Transplantation. Frontiers in Immunology. 2019
- The impact of IL-10 dynamic modulation on host immune response against visceral leishmaniasis. Cytokine. 2018
- L-Threonine Supplementation During Colitis Onset Delays Disease Recovery. Frontiers in Physiology. 2018
- Genetic deficiency of NOD2 confers resistance to invasive aspergillosis. Nature Communications. 2018
- Interleukin-6 Neutralization by Antibodies Immobilized at the Surface of Polymeric Nanoparticles as a Therapeutic Strategy for Arthritic Diseases. ACS Applied Materials and Interfaces. 2018
- Calcium sequestration by fungal melanin inhibits calcium-calmodulin signalling to prevent LC3-associated phagocytosis. Nature Microbiology. 2018
- Cytotoxic T lymphocyte antigen-4 gene polymorphisms and susceptibility to type 1 autoimmune hepatitis in the Tunisian population. Genes and Diseases. 2018
- Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes. JCI Insight. 2018
- Metabolic Regulation of Innate Immunity to Fungal Infection. EXS. 2018
- Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus. Nature. 2018
- Impact of Paracoccin Gene Silencing on Paracoccidioides brasiliensis Virulence. Mbio. 2017
- Evaluation of bronchoalveolar lavage fluid cytokines as biomarkers for invasive pulmonary aspergillosis in at-risk patients. Antibiotics. 2017
- Fungal Vaccines and Immunotherapeutics: Current Concepts and Future Challenges. Current Fungal Infection Reports. 2017
- The Cell Biology of the Trichosporon-Host Interaction. Frontiers in Cellular and Infection Microbiology. 2017
- The absence of NOD1 enhances killing of Aspergillus fumigatus through modulation of dectin-1 expression. Frontiers in Immunology. 2017
- The microbiome-metabolome crosstalk in the pathogenesis of respiratory fungal diseases. Virulence. 2017
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. Cell Metabolism. 2016
- Immunometabolic Pathways in BCG-Induced Trained Immunity. Cell Reports. 2016
- Genetic Variation in Autophagy-Related Genes Influences the Risk and Phenotype of Buruli Ulcer. PLoS Neglected Tropical Diseases. 2016
- Polymorphisms in Host Immunity-Modulating Genes and Risk of Invasive Aspergillosis: Results from the AspBIOmics Consortium.. Infection and Immunity. 2016
- Common genetic polymorphisms within NF¿B-related genes and the risk of developing invasive aspergillosis. Antibiotics. 2016
- The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells. Journal of Experimental Medicine. 2016
- Paving the way for predictive diagnostics and personalized treatment of invasive aspergillosis. Antibiotics. 2015
- Genetic PTX3 Deficiency and Aspergillosis in Stem-Cell Transplantation. New England Journal of Medicine. 2014
- Neutrophil Responses to Aspergillosis: New Roles for Old Players. Mycopathologia. 2014
- TLR9 Activation Dampens the Early Inflammatory Response to Paracoccidioides brasiliensis, Impacting Host Survival. PLoS Neglected Tropical Diseases. 2013
- Th17/Treg Imbalance in Murine Cystic Fibrosis Is Linked to Indoleamine 2,3-Dioxygenase Deficiency but Corrected by Kynurenines. American Journal of Respiratory and Critical Care Medicine. 2013
- CD4(+) T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease. Journal of Clinical Investigation. 2012
- DAMP signaling in fungal infections and diseases. Frontiers in Immunology. 2012
- Dectin-1 isoforms contribute to distinct Th1/Th17 cell activation in mucosal candidiasis. Cellular & Molecular Immunology. 2012
- From memory to antifungal vaccine design. Trends in Immunology. 2012
- Host defense pathways against fungi: The basis for vaccines and immunotherapy. Antibiotics. 2012
- Immunity and tolerance to fungi in hematopoietic transplantation: Principles and perspectives. Frontiers in Immunology. 2012
- Immunotherapy of aspergillosis. Clinical Microbiology and Infection. 2012
- TLR3 essentially promotes protective class I-restricted memory CD8 T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients. Blood. 2012
- The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma. Genes and Immunity. 2012
- The C Allele of rs5743836 Polymorphism in the Human TLR9 Promoter Links IL-6 and TLR9 Up-Regulation and Confers Increased B-Cell Proliferation. Antibiotics. 2011
- Genetic susceptibility to aspergillosis in allogeneic stem-cell transplantation. Blood. 2011
- Genetically-Determined Hyperfunction of the S100B/RAGE Axis Is a Risk Factor for Aspergillosis in Stem Cell Transplant Recipients. Antibiotics. 2011
- Immunity and tolerance to infections in experimental hematopoietic transplantation. Best Practice & Research Clinical Haematology. 2011
- Immunogenetic Profiling to Predict Risk of Invasive Fungal Diseases: Where Are We Now?. Immunological Investigations. 2011
- Cracking the Toll-like receptor code in fungal infections. Expert Review of Anti-Infective Therapy. 2010
- Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity. Blood. 2010
- Non-hematopoietic cells contribute to protective tolerance to Aspergillus fumigatus via a TRIF pathway converging on IDO. Cellular & Molecular Immunology. 2010
- Cdc42p controls yeast-cell shape and virulence of Paracoccidioides brasiliensis. Fungal Genetics and Biology. 2009
- Polymorphisms in Toll-like receptor genes and susceptibility to infections in allogeneic stem cell transplantation. Experimental Hematology. 2009
- T-1237C polymorphism of TLR9 gene is not associated with multiple sclerosis in the Portuguese population. Multiple Sclerosis. 2008
- Nitric Oxide Signaling Is Disrupted in the Yeast Model for Batten Disease. Endocrinology. 2007
- Multiplex PCR identification of eight clinically relevant Candida species. Blood. 2007
- Responses of antioxidant defenses to Cu and Zn stress in two aquatic fungi. Heredity. 2007
- Study of disease-relevant polymorphisms in the TLR4 and TLR9 genes: A novel method applied to the analysis of the Portuguese population. Molecular and Cellular Probes. 2007
- Towards a molecular genetic system for the pathogenic fungus Paracoccidioides brasiliensis. Fungal Genetics and Biology. 2007
capítulo de livro
documento
livro
- Immunogenetics of fungal diseases 2017
teses
- Management of fungal infections: diagnosis and human genetic susceptibility 2008