publicações selecionadas
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artigo académico
- Repurposing some of the Well-known Non-steroid Anti-inflammatoryDrugs (NSAIDs) for Cancer Treatment. Current Topics in Medicinal Chemistry. 2023
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artigo de revista
- Ursolic acid impairs cellular lipid homeostasis and lysosomal membrane integrity in breast carcinoma cells 2022
- Synthesis of Novel Methyl 3-(hetero)arylthieno[3,2-b]pyridine-2-carboxylates and Antitumor Activity Evaluation: Studies In Vitro and In Ovo Grafts of Chick Chorioallantoic Membrane (CAM) with a Triple Negative Breast Cancer Cell Line. Biomolecules. 2021
- Medicinal plants of the genuses Salvia and Hypericum are sources of anticolon cancer compounds: Effects on PI3K/Akt and MAP kinases pathways 2015
- Ursolic acid induces cell death and modulates autophagy through JNK pathway in apoptosis-resistant colorectal cancer cells. Journal of Nutritional Biochemistry. 2013
- Hypericum androsaemum water extract inhibits proliferation in human colorectal cancer cells through effects on MAP kinases and PI3K/Akt pathway. Food Bioscience. 2012
- Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation. Cancer Chemotherapy and Pharmacology. 2011
- Salvia fruticosa, salvia officinalis and rosmarinic acid induce apoptosis and inhibit proliferation of human colorectal cell lines: the role in MAPK/ERK pathway. Nutrition and Cancer-An International Journal. 2009
- Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells. Cancer Letters. 2009
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documento
- Chitinase 3-like-1 identified in large extracellular vesicles from human macrophages: a promising therapeutic drug target for pancreatic cancer (Best Poster Award in the session I of EVs in Cancer) 2023
- Darifenacin as novel chemosensitizer in pancreatic cancer 2023
- Efeito sensibilizador da darifenacina a agentes citotóxicos no cancro pancreático: estudo in silico e em linhas celulares 2022
- Targeting Chitinase-like-1 (CHI3L1) as a therapeutic target for pancreatic cancer 2021
- Identification of Chitinase 3-like 1 as a therapeutic target for pancreatic cancer in large extracellular vesicles from human macrophages 2021
- Targeting chitinase 3-like 1 in pancreatic cancer: in silico identification of inhibitors from a DrugBank database and confirmation of growth inhibition effect in cell lines 2021
- Should the diet of colon cancer patients be personalized based on gene mutation profiles of tumor cells 2016
- Ursolic acid, a dietary phytochemical, decreases KRAS signaling and modulates cell death pathways in resistant CRC cells 2012
- Quercetin enhances apoptosis induced by 5-fluorouracil in colorectal cancer cells through p53 modulation 2011
- Autophagy triggered by ursolic acid synergistically enhances 5-fluorouracil induced cell death in HCT15 (MSI p53 mutant) colorectal cancer cells 2011
- Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation 2011
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poster de conferência
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teses