publicações selecionadas
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artigo de conferência
- New valorization strategies for eucalyptus spp. bark extracts 2015
- DNA damage prevention and signaling pathway regulation by sage in a colon cancer model 2011
- Diet and colon cancer - modulation of signaling pathways and DNA damage prevention 2011
- Lab-on-a-chip for Measuring Uric Acid in Biological Fluids 2002
- Lab-on-a-chip for Measuring Uric Acid in Biological Fluids 2002
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artigo de revista
- Colon Cancer Chemoprevention by Sage Tea Drinking: Decreased DNA Damage and Cell Proliferation. Phytotherapy Research. 2015
- Biocompatibility of a self-assembled glycol chitosan nanogel. Toxicology in Vitro. 2015
- Invitro evaluation of bovine lactoferrin potential as an anticancer agent. International Dairy Journal. 2015
- Novel structurally similar chromene derivatives with opposing effects on p53 and apoptosis mechanisms in colorectal HCT116 cancer cells. European Journal of Pharmaceutical Sciences. 2015
- Redox-dependent induction of antioxidant defenses by phenolic diterpenes confers stress tolerance in normal human skin fibroblasts: Insights on replicative senescence. Free Radical Biology and Medicine. 2015
- Effects of biosurfactants on the viability and proliferation of human breast cancer cells. Amb Express. 2014
- Anticancer effects of lactoferrin: Underlying mechanisms and future trends in cancer therapy. Nutrition Reviews. 2014
- Bovine lactoferrin induces cell cycle arrest and inhibits mTOR signaling in breast cancer cells. Nutrition and Cancer. 2014
- Development of a new application of the comet assay to assess levels of O6-methylguanine in genomic DNA (CoMeth). Free Radical Biology and Medicine. 2013
- Ursolic acid induces cell death and modulates autophagy through JNK pathway in apoptosis-resistant colorectal cancer cells. Journal of Nutritional Biochemistry. 2013
- Hypericum androsaemum water extract inhibits proliferation in human colorectal cancer cells through effects on MAP kinases and PI3K/Akt pathway. Food Bioscience. 2012
- Keratin-based peptide: Biological evaluation and strengthening properties on relaxed hair. International Journal of Cosmetic Science. 2012
- Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation. Cancer Chemotherapy and Pharmacology. 2011
- Rosmarinic acid, major phenolic constituent of Greek sage herbal tea, modulates rat intestinal SGLT1 levels with effects on blood glucose. Molecular Nutrition & Food Research. 2011
- Curcumin induces heme oxygenase-1 in normal human skin fibroblasts through redox signaling: relevance for anti-aging intervention. Molecular Nutrition & Food Research. 2011
- Ursolic acid and luteolin-7-glucoside improves rat plasma lipid profile and increases liver glycogen content through glycogen synthase kinase-3. Phytotherapy Research. 2010
- Sage tea drinking improves lipid profile and antioxidant defences in Humans. International Journal of Molecular Sciences. 2009
- Salvia fruticosa, salvia officinalis and rosmarinic acid induce apoptosis and inhibit proliferation of human colorectal cell lines: the role in MAPK/ERK pathway. Nutrition and Cancer-An International Journal. 2009
- Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells. Cancer Letters. 2009
- Antigenotoxic effects of quercetin, rutin and ursolic acid on HepG2 cells: evaluation by the comet assay. Toxicology Letters. 2008
- Water and methanolic extracts of Salvia officinalis protect HepG2 cells from t-BHP induced oxidative damage. Chemico-Biological Interactions. 2007
- Drinking of Salvia officinalis tea increases CCl4-induced hepatotoxicity in mice. Food and Chemical Toxicology. 2007
- Metformin-like effect of salvia officinalis (common sage) : is it useful in diabetes prevention?. British Journal of Nutrition. 2006
- Phenolic compounds protect HepG2 cells from oxidative damage : relevance of glutathione levels. Life Sciences. 2006
- The drinking of a Salvia officinalis infusion improves liver antioxidant status in mice and rats. Journal of Ethnopharmacology. 2005
- Evaluation of toxic/protective effects of the essential oil of Salvia officinalis on freshly isolated rat hepatocytes. Toxicology in Vitro. 2004
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capítulo de livro
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documento
- 4,8-Disubstituted pyrimido[5,4-d]pyrimidines as novel apoptotic independent anticancer agents: synthesis and in vitro activity against HCT116 human colon cancer cells 2015
- Cytotoxic activity of water extract fractions of Hypericum androsaemum L. on colorectal cancer cells. Planta Medica. 2015
- New pyrimido[5,4-d]pyrimidines with enhanced anticancer activity on colorectal cancer cells: synthesis, SAR study and mechanism of action 2015
- New valorization strategies for Eucalyptus spp. bark extracts 2015
- Synthesis and anticancer activity of N3-substituted-6,8-diaminopurines 2015
- Novel synthetic molecules bioinspired in natural phenolic compounds for anticancer drug discovery 2014
- Novel structurally similar chromene derivatives with opposing effects on p53 and apoptosis mechanisms in colorectal HCT116 cancer cells 2014
- Synthesis and anticancer activity of 6-aryl Adenines 2013
- A new RGD dehydropeptide with hydrogelation properties 2012
- Diet and DNA damage: in vivo effects of dietary compounds on isolated colonocytes and lymphocytes from rats. European Journal of Cancer. 2012
- Diet supplemented with UA or EGCG confer protection against DNA damage in colonocytes 2012
- Elicitation of Hypericum perforatum cells with Agrobacterium tumefaciens induces production of bioactive phytochemicals that afford protection against oxidative stress induced in human HepG2 cells 2012
- Induction of antioxidant defences by diterpenic phenolics in human fibroblasts : relevance for ageing interventions 2012
- Synthesis and anticancer activity of 2,6,9-trisubstituted adenines 2012
- Synthesis and anticancer activity of novel chromeno-imidazo[1,2-a]pyridines 2012
- Ursolic acid, a dietary phytochemical, decreases KRAS signaling and modulates cell death pathways in resistant CRC cells 2012
- Cellular distribution and regulation of intestinal SGLT1 2011
- HepG2 cells under starvation-induced autophagy are susceptible to cell death caused by oleanolic acid but not by ursolic acid 2011
- Induction of antioxidant defenses by diterpenic phenolics in human fibroblasts for nutritional applications toward anti-aging interventions 2011
- Induction of antioxidant defenses in human HepG2 cells by a methanolic extract of hypericum perforatum cells elicited with agrobacterium tumefaciens 2011
- Curcumin-induced hormetic effects in human skin fibroblasts : implications toward anti-ageing interventions 2011
- Diet and colon cancer - modulation of signaling pathways and DNA damage prevention 2011
- Effects of natural compounds in lipid profile and metabolism in hepatocytes. Febs Journal. 2011
- Quercetin enhances apoptosis induced by 5-fluorouracil in colorectal cancer cells through p53 modulation 2011
- The role of some folk medicinal herbs and phytochemicals on hepatic lipid metabolism 2011
- Autophagy triggered by ursolic acid synergistically enhances 5-fluorouracil induced cell death in HCT15 (MSI p53 mutant) colorectal cancer cells 2011
- DNA damage prevention and signaling pathway regulation by sage in a colon cancer model 2011
- Induction of cellular stress responses by phytochemicals for nutritional applications toward anti-aging intervention 2011
- Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation 2011
- Induction of cellular stress responses by phytochemicals for nutritional applications toward anti-aging intervention 2010
- Sage drinking improves plasma lipid profile, erythrocyte antioxidant defences and increases lymphocyte HSP70 2007
- Effects of the regular intake of sage tea (Salvia Officinalis) in humans : a pilot trial 2006
- Evaluation of toxic and protective effects of an essential oil of Salvia officinalis L. on liver cells. Revista de Fitoterapia. 2002
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livro
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poster de conferência
- Quercetin synergistically induces sensitivity to 5-fluorouracil through p53 modulation in colorectal cancer cells 2011
- Antidiabetic potencial of Salvia fruticosa infusion: effects on intestinal glucose transporters 2004
- Efeitos antidiabéticos de plantas medicinais do género Salvia 2004
- Evaluation of toxic and protective effects of an essential oil of salvia officinalis L on liver cells 2002
- Hepatotoxicity of an essential oil of Salvia officinalis L.: an in vitro study using freshly isolated rat hepatocytes 2001
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teses