publicações selecionadas
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artigo académico
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artigo de revista
- Inhibition of human neutrophil oxidative burst by pyrazolone derivatives. Free Radical Biology and Medicine. 2006
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capítulo de livro
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documento
- Biomimetic membranes applied to the study of drug-membrane interactions: the case of celecoxib 2011
- Biophysical interactions of diclofenac with phospholipids bilayers: implications in mitochondrial toxicity 2011
- Biophysical interactions of rifabutin with phosphatidylcholine (DPPC) monolayers 2011
- Biophysical studies of the interactions between NSAIDs and membranes: insights on their modes of action 2011
- Comparison among of biomimetic lipid aggregates as in vitro models to assess antioxidant capacity against peroxidation 2011
- In vitro assessment of meloxicam effects on biomembranes 2011
- In vitro evaluation of the pharmacokinetics of nimesculide and meloxicam 2011
- Interactions of diclofenac with phospholipid bilayers: effects on membrane biophysics and nanoscale lipid membrane organization. 2011
- Lipid nanoparticles for topical and transdermal application for cellulite treatment 2011
- Lipid-drug interaction: biophysical and structural effects of Celecoxib on membrane mimetic systems 2011
- Membrane biophysical studies as a tool to understand the mechanism of action of antitubercular drugs 2011
- NSAIDs interactions with membranes: a biophysical approach 2011
- Understanding the therapeutic and toxic mechanisms of action of non-steroidal anti-inflammatory drugs through the use of biomimetic models 2011
- A reagent-free method based on photo-induced fluorimetry in a sequential injection system 2010
- Activity and inhibition of bee venom phospholipase A2 studied by fluorescent methodologies 2010
- Determining drug-serum protein binding interaction 2010
- Development of novel lipid nanoparticles to encapsulate resveratrol for further preparation of a nutraceutical 2010
- Effect of antibercular drugs on membrane biophysics: implications for drugs mode of action 2010
- Evaluation of toxicological effects of drugs on the prospects of membrane biophysics 2010
- Interaction mechanism of clonixin and lornoxicam with human serum albumin 2010
- Interaction of flunixin and dipyrone with human serum albumin: fluorescence studies 2010
- Interaction of resveratrol with model membranes 2010
- Methodologies for evaluation of peroxyl radical scavenging activity in hydrophobic or hydrophilic conditions using biometric systems 2010
- Microplate fluorimetric methodologies to assess antioxidant activity at different locations on phospholipid membranes 2010
- Perturbing effects of piroxicam on a model membrane system: role in its chemopreventive function 2010
- Phospholipase A2 as a control point in the diversity of lipid mediators 2010
- Preparation and characterization of PLGA nanoparticles containing a non-steroidal anti-inflammatory agent 2010
- Preparation and characterization of solid lipid nanoparticles (SLN) applied to deliver resveratrol in beverages 2010
- The interaction of celecoxib with membranares: a biophysical study 2010
- The role of drug-membrane interactions in the cardiovascular effects of b-blockers 2010
- Development and validation of an improved oxygen radical absorbance capacity assay using biomimetic systems 2009
- Drug release studies on functionalized sílica nanotubes 2009
- Influence of NSAIDs on the activity of enzymes at interfaces 2009
- Magnetic nanotubes and nanowires in porous alumina membranes for biomedical applications 2009
- Membrane biophysical studies for evaluations of toxicological effects of pharmaceutical compounds 2009
- Perturbations on the biophysical properties of membranes revealed by fluorescence steady-state and lifetime studies 2009
- Studies for improving therapeutic effects of drugs: the role of membrane biophysics and drug-membrane interactions. 2009
- Biophysical changes on membranes after NSAIDs contact 2008
- Development of an automatic methodology for the assessment of the anti-inflammatory drugs’ inhibitory effect on phospholipase A2 2008
- Drug-membrane interactions enhance the scavenging activity against reactive oxygen species 2008
- Evaluation of the interaction of ibuprofen and indomethacin with membrane models 2008
- Importance of drug-membrane interaction studies for the rational development of therapeutic applications 2008
- Interaction of NSAIDS with DMPC liposomes: studies of partition, location and membrane fluidity 2008
- Interactions between NSAIDS and membrane bilayers: an explanation for their different mode of action 2008
- Membrane biophysics modification promoted by NSAID 2008
- Molecular mechanisms underlying therapeutic and toxic effects of anti-inflammatory drugs 2008
- Perturbing effects of b-blockers on a model membrane system: role of lipophilicity and chemical structure 2008
- Phospholipase A2, NSAIDs and lipid interactions 2008
- Silica nanotubes as drug delivery systems: tuning the surface functionalization for an efficient drug release 2008
- Study of activity and inhibition of phospholipase A2 by the action of meloxicam 2008
- Surface modification of silica nanotubes for efficient drug release 2008
- The role of membrane interactions to evaluate the antioxidant profile of pharmaceutical drugs 2008
- Evaluation of the effect of phenolic compounds on cell membrane fluidity 2007
- Evaluation of the effect of some non-steroidal anti-inflammatory drugs on cell membrane fluidity 2007
- Fluorescence studies of the biophysical interaction of a fusogenic peptide with membrane model systems 2007
- Implementation of a methodology for evaluation of phospholipase activity 2007
- Role of liposomes as analytical tools to evaluate the antioxidant profile of pharmaceutical drugs 2007
- Study of the chemical interaction of drugs with membrane phospholipids and its influence on the structural lipidic organization 2007
- Use of biomimetic models in the evaluation of the interaction of oxaprozim, sulindac and sulindac sulphide with biological membranes 2007
- Evaluation of NSAIDs antioxidant activity in a liposomal model system 2006
- Interaction of nonsteroidal anti-inflammatory drugs (NSAIDs) with gastric surface active phospholipids: a possible mechanism for the gastric toxicity 2006
- Effect of non-steroidal anti-inflammatories on lipid peroxidation induced by hydroxyl radicals 2005
- Evaluation of the antioxidant capacity of non-steroidal anti-inflammatory drugs in membrane models 2005
- Interaction of non-steroidal anti-inflammatory drugs (NSAIDS) with large unilamellar liposomes: application of fluorescence methodologies 2005
- On the importance of drug-membrane interactions: A study of non steroidal anti-inflammatory drugs with liposomes as biological membrane models 2005
- Relationship between the ability of NSAIDS to alter the membrane fluidity and their antioxidant activity 2005
- Interaction of oxicams with EPC liposomes used as membrane models 2004
- Liposomes as biological membrane models aiming a better understanding of the mode of action of non-steroidal anti-inflammatory drugs 2004
- NSAIDs’antioxidant activity: any influence in therapeutic and toxic effects? 2004
- Oxicams inhibit oxidative damage in membrane models: scavenging oxyradicals or changing membrane fluidity? 2004
- Studies of sulindac induced perturbations inn membrane models aiming a better understanding of therapeutical and toxic effects 2004
- Effect of anti-inflammatory drugs in membrane fluidity in the presence of free radicals 2003
- Evaluation of the location of non-steroidal anti-inflammatories in liposomes by fluorescence inactivation studies 2003
- Evaluation of the partition coefficient of non-steroidal anti-inflammatory drugs in hexadeciphosphocholine micelles by derivative spectrophotometry 2003
- Fluidity/peroxidation relationship using liposomes as membrane models 2003
- Influence of anti-inflammatory drugs in membrane fluidity studied by fluorescence anisotropy measurements 2003
- Quantifying the maximum membrane uptake of drugs by measuring zeta-potentials 2003
- Study of membrane alterations caused by sulindac and its metabolites 2003
- Spectroscopic determination of the participation coefficient of non-steroidal anti-inflammatory drugs in liposomes 2001