publicações selecionadas
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artigo académico
- Enhancement of Acetate-Induced Apoptosis of Colorectal Cancer Cells by Cathepsin D Inhibition Depends on Oligomycin A-Sensitive Respiration. Biomolecules. 2024
- Economic evaluation of biological treatments in patients with severe asthma: a systematic review. Expert Review of Pharmacoeconomics & Outcomes Research. 2023
- The Yeast Saccharomyces cerevisiae as a Model for Understanding RAS Proteins and their Role in Human Tumorigenesis. Cells. 2018
- Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis. BMC Cancer. 2016
- Cathepsin D protects colorectal cancer cells from acetate-induced apoptosis through autophagy-independent degradation of damaged mitochondria. Cell Death and Differentiation. 2015
- Colorectal cancer-related mutant KRAS alleles function as positive regulators of autophagy. Oncotarget. 2015
- RAF-1 promotes survival of thyroid cancer cells harboring RET/PTC1 rearrangement independently of ERK activation. Molecular and Cellular Endocrinology. 2015
- Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D release. Cell Death and Differentiation. 2013
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artigo de conferência
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documento
- Dissecting the impact of KRAS/ Galectin-3 complex on colorectal tumor microenvironment 2019
- Unveil the KRAS/Galectin-3/p16INK4a triple axis regulation in colorectal cancer 2018
- Mitochondrial ROS accumulation sensitizes colorectal cancer cells to acetate and Cathepsin D inhibitors combination therapy 2017
- Yeast as a tool to identify novel kinases involved in regulation of Bax 2015
- Yeast as a system model to characterize Bax regulation by individual kinases 2015
- Cathepsin D is involved in the degradation of damaged mitochondria during acetate-induced apoptosis in colorectal cancer cells. 2015
- Impact of mutated KRAS signalling on autophagy regulation in colorectal carcinoma 2014
- Vacuole-mitochondrial crosstalk during apoptosis induced by acetic acid in yeast 2011
- What yeast can tell us about how cells commit suicide? 2011
- Regulação da autofagia pelo KRAS de modo a compreender o seu papel no cancro humano 2009