publicações selecionadas
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artigo académico
- Mitochondrial Dysfunction and Decreased Cytochrome c in Cell and Animal Models of Machado-Joseph Disease. Cells. 2023
- The Sigma-1 Receptor Mediates Pridopidine Rescue of Mitochondrial Function in Huntington Disease Models. Neurotherapeutics. 2021
- Mitochondrial SIRT3 confers neuroprotection in Huntington's disease by regulation of oxidative challenges and mitochondrial dynamics. Free Radical Biology and Medicine. 2021
- SIRT 3 , a modifier of mitochondrial function in Huntington's disease. Free Radical Biology and Medicine. 2018
- Insulin and IGF-1 regularize energy metabolites in neural cells expressing full-length mutant huntingtin. Neuropeptides. 2016
- Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease. PLoS ONE (IF=3.234). 2015
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artigo de conferência
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capítulo de livro
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documento
- I13 Pridopidine restores mitochondrial function and decreases er stress which is mediated through the S1R 2021
- Pridopidine preserves mitochondrial morphofunction in in vitro and ex vivo Huntington's models through sigma-1 receptor-dependent decrease in oxidative stress 2019
- Exacerbated SIRT3 activity alters mitochondrial function and dynamics in Huntington's disease models 2016