publicações selecionadas
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artigo académico
- Antimicrobial Activity and Mechanism of Action of New N-heteroaryl-1H- (benz)Imidazoles. Mini-Reviews in Medicinal Chemistry. 2014
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Regiocontrolled S
N Ar reaction on 2,3-dihalopyridines with NaSMe to obtain bromo(methylthio)pyridines as key precursors of 3-halo-2-(hetero) arylthieno[2,3- b ]pyridines and thieno[3,2- b ]pyridines. Synthesis. 2013 - Scope and Limitations of the Base-Free Copper(I) Oxide CatalyzedN-Heteroarylation of 1H-(Benz)imidazoles withB-Heteroarylboronic Acids or 2-Heteroaryl-4,4,5,5-tetramethyl-1,3,2-dioxaborolanes. Helvetica Chimica Acta. 2013
- Tandem Palladium/Charcoal-Copper(I) Iodide (Pd/C-CuI) Catalyzed Sonogashira Coupling and Intramolecular Cyclization from 2-Bromonicotinic Acid (=2-Bromopyridine-3-carboxylic Acid) and Ethynylarenes to 4-Azaphthalides (=Furo[3,4-b]pyridin-5(7H)-ones) and 5. Helvetica Chimica Acta. 2011
- Palladium-Catalysed Multicomponent Aminocarbonylation of Aryl or Heteroaryl Halides with [Mo(CO)6] and Aryl- or Heteroarylamines Using Conventional Heating. European Journal of Organic Chemistry. 2009
- Antifungal activity of synthetic di(hetero)arylamines based on the benzo[b]thiophene moiety. Bioorganic & Medicinal Chemistry. 2008
- Palladium-Catalyzed Buchwald-Hartwig Coupling of Deactivated Aminothiophenes with Substituted Halopyridines. European Journal of Organic Chemistry. 2007
- Reactivity of Substituted Bromothiophenecarboxylates in Palladium-Catalyzed N-Arylation of Hetarylamines. Synthesis. 2006
- Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power. Bioorganic & Medicinal Chemistry Letters. 2006
- Synthesis of Diarylamines in the Thiophene Series by Buchwald-Hartwig Coupling. Synthesis. 2005
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artigo de revista
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Synthesis of 2-(hetero)arylthieno[2,3-b] or [3,2-b]pyridines from 2,3-dihalopyridines, (hetero)arylalkynes, and Na
2 S. Further functionalizations. Tetrahedron. 2012 - Synthesis of the first thieno-d-carboline. Fluorescence studies in solution and in lipid vesicles. Journal of Photochemistry and Photobiology A-Chemistry. 2006
- Palladium-Catalysed Amination of Electron-Deficient or Relatively Electron-Rich Benzo[b]thienyl Bromides- Preliminary Studies of Antimicrobial Activity and SARs. European Journal of Organic Chemistry. 2004
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Synthesis of 2-(hetero)arylthieno[2,3-b] or [3,2-b]pyridines from 2,3-dihalopyridines, (hetero)arylalkynes, and Na
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documento
- Virtual screening of thieno[3,2-b]pyridine arylthioether (hetero)aryltriazole derivatives as potential tyrosine kinase VEGFR2 inhibitors. 2013
- Synthesis of 3-halo-2-(hetero)arylthienopyridine derivatives as key precursors of potential antitumorals 2013
- Synthesis of new n-[3-(thieno[3,2-b]pyridine-7-ylthio)phenyl]benzamides as potential inhibitors of VEGFR2 using rational design 2013
- Synthesis of thienopyridine derivatives as potential antitumorals and/or antiangiogenics 2013
- Synthesis of new N-[3-(thieno[3,2-b]pyridine-7-ylthio)phenyl]benzamides as potential inhibitors the tyrosine kinase domain of VEGFR2 2013
- Synthesis of thienopyridine derivatives as potential antitumorals and/or antiangiogenics 2012
- Synthesis of 3-Halo-2-(hetero)arylthienopyridines through a tree-step methodology from 2,3-dihalopyridines, methanethiolate, (hetero)arylalkynes and electrophiles 2012
- Synthesis of 3-Halo-2-(Hetero)Arylthienopyridines through a three-step methodology from 2,3-Dihalopyridines, Methanethiolate, (Hetero)Arylalkynes and Electrophiles 2012