resumo Supplementary material related to this article can be found, in the online version, at doi:https://doi.org/10.1016/j.nbt.2018.12.002.
autores Fernando Octávio de Queirós Dourado Dourado, Fernando Rodrigues, Ana Cristina Fontão, A. Gama, F. M. Rodrigues, Ana Cristina Fontão, A. Coelho, Aires Leal, M. Silva, Francisco Almeida Garrett Soares Wan, Yizao Aksoy-Aksel, A.
palavras-chave BNC production optimization Culture medium depth Low-cost substrates Response surface methodology-central composite design Surface area