publicações selecionadas
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artigo académico
- Current and Novel Approaches in Yeast Cell Death Research. Cell Death and Differentiation. 2024
- Enhancement of Acetate-Induced Apoptosis of Colorectal Cancer Cells by Cathepsin D Inhibition Depends on Oligomycin A-Sensitive Respiration. Biomolecules. 2024
- A versatile yeast model to screen for pesticides as risk factors for synucleinopathies. Chemosphere. 2024
- Bovine Lactoferrin-Loaded Plasmonic Magnetoliposomes for Antifungal Therapeutic Applications. Pharmaceutics. 2023
- Monitoring yeast regulated cell death: trespassing the point of no return to loss of plasma membrane integrity. Apoptosis. 2022
- Plasmalemmal V-ATPase as a Potential Biomarker for Lactoferrin-Based Anticancer Therapy. Biomolecules. 2022
- Lactate induces cisplatin resistance in S. cerevisiae through a Rad4p-dependent process. Oxidative Medicine and Cellular Longevity. 2020
- Pkh1p-Ypk1p and Pkh1p-Sch9p Pathways Are Activated by Acetic Acid to Induce a Mitochondrial-Dependent Regulated Cell Death. Oxidative Medicine and Cellular Longevity. 2020
- Acetic acid induces Sch9p-dependent translocation of Isc1p from the endoplasmic reticulum into mitochondria. Biochimica et Biophysica Acta (BBA). Molecular and Cell Biology of Lipids. 2018
- New perspectives from South-Y-East, not all about death A report of the 12th lnternational Meeting on Yeast Apoptosis in Bari, Italy, May 14th-18th, 2017. Microbial Cell. 2018
- Yeast on the corner of life and death decisions. Mechanisms of Ageing and Development. 2017
- Cell wall dynamics modulate acetic acid-induced apoptotic cell death of Saccharomyces cerevisiae. Microbial Cell. 2014
- The yeast model system as a tool towards the understanding of apoptosis regulation by sphingolipids. FEMS Yeast Research. 2013
- The protective role of yeast Cathepsin D in acetic acid-induced apoptosis depends on ANT (Aac2p) but not on the voltage-dependent channel (Por1p). FEBS Letters. 2012
- Remoção zimológica da acidez volátil e fixa de mostos e vinhos: da fisiologia à manipulação genética de leveduras 2000
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artigo de conferência
- Bridging the gap between lactoferrin and V-ATPase through a multi-stage computational approach 2021
- Comunicar ciência: a formação em competências transversais dos estudantes de doutoramento da Escola de Ciências da Universidade do Minho 2018
- Delayed fatty acid uptake by a fatty acid secreting yeast strain with modified peroxisomal metabolism 2011
- MAPK signaling pathways mediate acetic acid-induced cell death in saccharomyces cerevisiae 2011
- Suppressing fatty acid uptake by a fatty acid secreting saccharomyces cerevisiae strain 2011
- Engineering of fatty acid production and secretion in Saccharomyces cerevisiae 2009
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artigo de revista
- Synthesis and Cytotoxicity Assessment of Citrate-Coated Calcium and Manganese Ferrite Nanoparticles for Magnetic Hyperthermia. Pharmaceutics. 2022
- Lactoferrin perturbs intracellular trafficking, disrupts cholesterol-rich lipid rafts and inhibits glycolysis of highly metastatic cancer cells harbouring plasmalemmal V-ATPase. International Journal of Biological Macromolecules. 2022
- Acetic acid triggers cytochrome c release in yeast heterologously expressing human Bax. Apoptosis. 2022
- A review on lactoferrin as a proton pump inhibitor. International Journal of Biological Macromolecules. 2022
- Saccharomyces cerevisiae Cells Lacking the Zinc Vacuolar Transporter Zrt3 Display Improved Ethanol Productivity in Lignocellulosic Hydrolysates. Journal of Fungi. 2022
- The milk-derived lactoferrin inhibits V-ATPase activity by targeting its V1 domain. International Journal of Biological Macromolecules. 2021
- Regulation of Cell Death Induced by Acetic Acid in Yeasts. Frontiers in Cell and Developmental Biology. 2021
- Lactoferrin perturbs lipid rafts and requires integrity of Pma1p-lipid rafts association to exert its antifungal activity against Saccharomyces cerevisiae. International Journal of Biological Macromolecules. 2021
- Emerging insights on the role of V-ATPase in human diseases: Therapeutic challenges and opportunities. Medicinal Research Reviews. 2021
- The Role of Diet Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications. Current Medicinal Chemistry. 2020
- Lactate Induces Cisplatin Resistance in S. cerevisiae through a Rad4p-Dependent Process. Oxidative Medicine and Cellular Longevity. 2020
- Resveratrol-Loaded Lipid Nanocarriers Are Internalized By Endocytosis in Yeast. Journal of Natural Products. 2019
- Contacts in death: The role of the ER-mitochondria axis in acetic acid-induced apoptosis in yeast. Journal of Molecular Biology. 2019
- Proteasome inhibition prevents cell death induced by the chemotherapeutic agent cisplatin downstream of DNA damage. DNA Repair. 2019
- Bovine Milk Lactoferrin Selectively Kills Highly Metastatic Prostate Cancer PC-3 and Osteosarcoma MG-63 Cells In Vitro. Frontiers in Oncology. 2018
- The Yeast Saccharomyces cerevisiae as a Model for Understanding RAS Proteins and their Role in Human Tumorigenesis. Cells. 2018
- Guidelines and recommendations on yeast cell death nomenclature. Microbial Cell. 2018
- VDAC regulates AAC-mediated apoptosis and cytochrome c release in yeast. Microbial Cell. 2016
- Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemmal V-H+-ATPase. Oncotarget. 2016
- Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications. Oncotarget. 2016
- Counter ions and constituents combination affect DODAX:MO nanocarriers toxicity: In vitro and in vivo. Toxicology Research. 2016
- Regulation of Bax/mitochondria interaction by AKT. FEBS Letters. 2016
- Human lactoferrin triggers a mitochondrial- and caspase-dependent regulated cell death in Saccharomyces cerevisiae. Apoptosis. 2015
- Ceramide signalling impinges on Sit4p and Hog1p to promote mitochondrial fission and mitophagy in Isc1p-deficient cells. Cellular Signalling. 2015
- Cathepsin D protects colorectal cancer cells from acetate-induced apoptosis through autophagy-independent degradation of damaged mitochondria. Cell Death and Differentiation. 2015
- Colorectal cancer-related mutant KRAS alleles function as positive regulators of autophagy. Oncotarget. 2015
- Combined use of Wallerstein and Zygosaccharomyces bailii modified differential media to isolate yeasts for the controlled reduction of volatile acidity of grape musts and wines 2015
- Yeast as a tool to explore cathepsin D function. Microbial Cell. 2015
- High gravity primary continuous beer fermentation using flocculent yeast biomass. Journal of the Institute of Brewing. 2014
- Maintaining yeast viability in continuous primary beer fermentation. Journal of the Institute of Brewing. 2014
- C2-Phytoceramide Perturbs Lipid Rafts and Cell Integrity in Saccharomyces cerevisiae in a Sterol-Dependent Manner. Antibiotics. 2013
- Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D release. Cell Death and Differentiation. 2013
- Genome-wide identification of genes involved in the positive and negative regulation of acetic acid-induced programmed cell death in Saccharomyces cerevisiae. BMC Genomics. 2013
- Modulation of Mitochondrial Outer Membrane Permeabilization and Apoptosis by Ceramide Metabolism. Antibiotics. 2012
- The Fate of Acetic Acid during Glucose Co-Metabolism by the Spoilage Yeast Zygosaccharomyces bailii. Antibiotics. 2012
- Distinct regulation of p53-mediated apoptosis by protein kinase calpha, delta, epsilon and zeta: evidence in yeast for transcription-dependent and -independent p53 apoptotic mechanisms. Experimental Cell Research. 2011
- Modulation of bax mitochondrial insertion and induced cell death in yeast by mammalian protein kinase calpha. Experimental Cell Research. 2011
- New observations on the integrity, structure, and physiology of flesh cells from fully ripened grape berry. American Journal of Enology and Viticulture. 2011
- The impact of acetate metabolism on yeast fermentative performance and wine quality: reduction of volatile acidity of grape musts and wines. Applied Microbiology and Biotechnology. 2011
- The importance of humanized yeast to better understand the role of Bcl-2 family in apoptosis : finding of novel therapeutic opportunities. Current Pharmaceutical Design. 2011
- Vacuole-mitochondrial cross-talk during apoptosis in yeast: A model for understanding lysosome-mitochondria-mediated apoptosis in mammals. Biochemical SocIETy Transactions. 2011
- Desacidificação zimológica de ácido acético de mostos e vinhos 2010
- Effect of refermentation conditions and microoxygenation on the reduction of volatile acidity by commercial S. cerevisiae strains and their impact on the aromatic profile of wines. International Journal of Food Microbiology. 2010
- Effects of acetic acid, ethanol and SO2 on the removal of volatile acidity from acidic wines by two Saccharomyces cerevisiae commercial strains. Applied Microbiology and Biotechnology. 2010
- Selective activation of protein kinase C-δ and -ɛ by 6,11,12,14-tetrahydroxy-abieta-5,8,11,13-tetraene-7-one (coleon U). Biochemical Pharmacology. 2009
- Reduction of volatile acidity of wines by selected yeast strains. Applied Microbiology and Biotechnology. 2008
- Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and apoptosis. Endocrinology. 2008
- Acid stress adaptation protects saccharomyces cerevisiae from acetic acid-induced programme cell death. Gene. 2005
- Hyperosmotic stress induces metacaspase - and mitochondria - dependent apoptosis in Saccharomyces cerevisiae. Molecular Microbiology. 2005
- An AIF orthologue regulates apoptosis in yeast. Journal of Cell Biology. 2004
- Isolation of an acetyl-CoA synthetase gene (ZbACS2) from Zygosaccharomyces bailii. Yeast. 2004
- Energy conversion coupled to cyanide-resistant respiration in the yeasts and. FEMS Yeast Research. 2003
- Acetic acid induces a programmed cell death process in the food spoilage yeast Zygosaccharomyces bailii. FEMS Yeast Research. 2003
- The Spoilage Yeast Zygosaccharomyces bailii Forms Mitotic Spores: a Screening Method for Haploidization. Applied and Environmental Microbiology. 2003
- Cytochrome c release and mitochondria involvement in programmed cell death induced by acetic acid in Saccharomyces cerevisiae. Endocrinology. 2002
- Remoção zimológica da acidez volátil e fixa de mostos e vinhos: da fisiologia à manipulação genética de leveduras 2000
- A differential medium for the enumeration of the spollage yeast zygosaccharomyces bailii in wine. Journal of Food Protection. 2000
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capítulo de livro
- Flow Cytometry and Fluorescence Microscopy as Tools for Structural and Functional Analysis of Vacuoles Isolated from Yeast and Plant Cells. Methods in Molecular Biology. 2018
- Flow Cytometry and Fluorescence Microscopy as Tools for Structural and Functional Analysis of Vacuoles Isolated from Yeast and Plant Cells. Methods in Molecular Biology. 2018
- Use of a differential culture medium for the enumeration of Zygosaccharomyces bailii, Saccharomyces cerevisiae and Pichia membranifaciens in wine 2002
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documento
- Manuscript in Preparation: Recovery of acidic wines through bio-reduction of their volatile acidity using yeast cells 2024
- Bio-reduction of wine volatile acidity using yeast cells 2023
- Exploitation of Saccharomyces cerevisiae mutants deficient in genes encoding vacuolar proteins towards the improvement of its fermentative performance in lignocellulosic hydrolysates 2023
- Bridging the gap between lactoferrin and V-ATPase through a multi-stage computational approach 2021
- Acetic acid as a trigger to activate human Bax heterologously expressed in yeast 2021
- Elucidating the interaction of lactoferrin with V-ATPase towards understanding its mechanisms of action 2021
- Deciphering the interaction of lactoferrin with V-ATPase towardsa deeper understanding of its mechanisms of action 2021
- Unveil the role of KRAS mutations in glycolytic metabolism 2020
- Computational approach to study the interaction between the milk protein lactoferrin and V-ATPase 2019
- Lactoferrin is selectively cytotoxic for highly metastatic cancer cells by inhibiting plasmalemmal V-ATPase 2019
- Carbon source affects sensitivity to the anti-cancer agent cisplatin in Saccharomyces cerevisiae 2019
- The impact of zinc in yeast cell death induced by acetic acid 2019
- Which molecular mechanisms are involved in the antifungal activity of the milk-derived protein lactoferrin? 2019
- The role of membrane lipid domains on lactoferrin anticancer activity: from yeast to human cells 2019
- The role of zinc in acetic acid-induced cell death in yeast 2019
- Uncovering the role of vacuolar membrane proteins On Pep4P translocation/vacuolar membrane permeabilization during acetic acid-induced cell death 2019
- Yeast cells expressing human Bax as a tool to study its activation and regulation 2019
- How carbon source affects the sensitivity to the anti-cancer agent cisplatin 2019
- How can a milk protein selectively kill cancer cells? Mechanisms underlying lactoferrin-induced apoptosis 2019
- How does the milk protein lactoferrin bind to V-ATPase? 2018
- Studying the effect of bovine milk lactoferrin on the plasma membrane of yeast and human cells 2018
- The highly metastatic prostate cancer PC-3 and osteosarcoma MG-63 cell lines are sensitive to bovine lactoferrin 2018
- The yeast Saccharomyces cerevisiae as a model organism to exploit the regulation of the human pro-apoptotic protein Bax 2018
- Uncovering the role of vacuolar membrane proteins in acetic acid-induced cell death 2018
- Yeast Saccharomyces cerevisiae as a model organism to exploit the regulation of the human pro-apoptotic protein Bax 2018
- The effect of carbon source in the sensitivity to the anti-cancer agent cisplatin 2018
- How can a milk protein selectively kill cancer cells? Mechanisms underlying lactoferrin-induced apoptosis 2018
- Lactoferrin perturbs intracellular trafficking in yeast and highly metastatic cancer cells 2018
- Deciphering the mechanisms underlying bovine milk lactoferrin anticancer activity using yeast and cancer cell lines as complementary models 2018
- Role of vacuolar membrane proteins in acetic acid-induced cell death 2018
- Yeast as a cell model to study the human pro-apoptotic protein Bax 2018
- Exploring a novel effec of lactoferrin on the plasma membrane towards the elucidation of the mechanisms of action: from yeast to human cells 2018
- Exploring a novel effec of lactoferrin on the plasma membrane towards the elucidation of the mechanisms of action: from yeast to human cells 2017
- The role of metabolism in the sensitivity of S. cerevisiae to the anti-cancer agent cisplatin 2017
- Exploring a novel effect of lactoferrin on the plasma membrane towards the elucidation of the mechanisms of action: from yeast to human cells 2017
- Mitochondrial ROS accumulation sensitizes colorectal cancer cells to acetate and Cathepsin D inhibitors combination therapy 2017
- Yeast as a tool to understand proteasome-mediated sensitivity to the chemotherapeutic agent cisplatin 2017
- The role of metabolism in the sensitivity of S. cerevisiae to the anti-cancer agent cisplatin. 2016
- Insights on the Molecular Mechanisms Underlying the Anticancer Activity of Lactoferrin in Highly Metastatic Cancer Cell Lines 2016
- Insights on the molecular mechanisms underlying the anticancer activity of lactoferrin in metastatic cancer cell lines 2016
- Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemal V-H+-ATPase 2016
- Transport of short chain fatty acids and 3-bromopyruvate in cancer cells: implications for cancer therapy 2016
- Yeast as a tool to identify novel kinases involved in regulation of Bax 2015
- Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemal V-H+-ATPase 2015
- Yeast as a system model to characterize Bax regulation by individual kinases 2015
- Cathepsin D is involved in the degradation of damaged mitochondria during acetate-induced apoptosis in colorectal cancer cells. 2015
- Cathepsin D protects colorectal cancer cells from acetate-induced apoptosis through autophagy-independent degradation of damaged mitochondria 2015
- An in vitro approach towards the elucidation of the mechanisms of action of lactoferrin 2014
- Functional characterization of mitochondrial suspensions by flow cytometry towards the screening of mitochondrial drug targets 2014
- Search for mechanisms underlying the anti-tumoral activity of lactoferrin 2014
- Human lactoferrin triggers a caspase- and mitochondrial-dependent programmed cell death in Saccharomyces cerevisiae 2014
- Mitochondria involvement in human lactoferrin-induced programmed cell death in Saccharomyces cerevisiae 2014
- Yeast programed cell death and aging. Frontiers in Oncology. 2013
- Vacuole-mitochondrial crosstalk during apoptosis induced by acetic acid in yeast 2011
- Genome-wide identification of genes involved in the positive and negative regulation of acetic acid-induced cell death in saccharomyces cerevisiae 2011
- Role of C2-phytoceramide in mediating cell death in yeast 2011
- Role of ceramides and ceramides-formed pores in the process of mitochondria permeabilization and yeast programmed cell death 2011
- Use of immobilized saccharomyces cerevisiae cells to reduce volatile acidity of acidic wines 2011
- Modulation of Bax by Protein Kinase C in yeast 2011
- Assessment of oxidative modification of the Aac2p carrier and its contribution to a PTP-like function in yeast mitochondria 2011
- MAPK signaling pathways mediate acetic acid-induced cell death in saccharomyces cerevisiae 2011
- Protective effect of acetic acid against ethanol-induced cell death in Saccharomyces cerevisiae 2011
- Suppressing fatty acid uptake by a fatty acid secreting saccharomyces cerevisiae strain 2011
- The involvement of sphingolipids in apoptosis induced by acetic acid in yeast 2011
- What yeast can tell us about how cells commit suicide? 2011
- Isolation of yeast strains with ability to reduce volatile acidity of wines 2009
- Reduction of volatile acidity of wines by isolated and commercial yeast strains 2008
- Characterization and identification of wine yeasts with ability to use acetic acid 2006
- Isolation and characterization of yeast strains with ability to decrease volatile acidity of wines 2005
- Flow cytometry as a tool to assess cytotoxic effects of the non-ionic surfactant Triton X-100 in Tetrahymena pyriformis 2003
- Remoção Zimológica da acidez volátil e fixa de mostos e vinhos: da fisiologia à manipulação genética de leveduras. 2000
- Remoção zimológica da acidez volátil e fixa de mostos e vinhos: da fisiologia à manipulação genética de leveduras 2000
- Desenho de um meio diferencial para detecção da levedura de contaminação alimentar Zygosaccharomyces bailii 1997
- Differential medium for the detection of the food and beverage spoilage yeast Zygosaccharomyces bailii 1997
- Selective media as a rapid method for the differentiation of the spoilage yeast Zygosaccharomyces bailii from food and beverages 1996
- Bovine Lactoferrin Loaded Magnetic-Responsive Plasmonic Lipo-Somes for Therapeutic Applications
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poster de conferência
- Delayed fatty acid uptake by a fatty acid secreting yeast strain with modified peroxisomal metabolism 2011
- Use of immobilized saccharomyces cerevisiae cells to reduce volatile acidity of acidic wines 2011
- Engineering of fatty acid production and secretion in Saccharomyces cerevisiae 2010
- Engineering of fatty acid production and secretion in Saccharomyces cerevisiae 2009
- The effect of micro-oxygenation and cell immobilization on the reduction of excessive volatile acidity from wines 2009
- Isolation of yeast strains with ability to reduce volatile acidity of wines 2007
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teses