publicações selecionadas
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artigo académico
- Inflammation and Exosomes in Fabry Disease Pathogenesis. Cells. 2024
- Discovery of 2,9-diaryl-6-carbamoylpurines as a novel class of antitubercular agents. European Journal of Medicinal Chemistry. 2024
- Repurposing of statins for Buruli Ulcer treatment: antimicrobial activity against Mycobacterium ulcerans. Antibiotics. 2023
- Repetitive mRNA vaccination is required to improve the quality of broad-spectrum anti-SARS-CoV-2 antibodies in the absence of CXCL13.. Science Advances. 2023
- Gellan gum spongy-like hydrogel-based dual antibiotic therapy for infected diabetic wounds. Bioengineering & Translational Medicine. 2023
- Post-acute sequelae of COVID-19 is characterized by diminished peripheral CD8+ß7 integrin+ T cells and anti-SARS-CoV-2 IgA response. Nature Communications. 2023
- An optimized mouse model of Staphylococcus aureus infected diabetic ulcers. BMC Research Notes. 2022
- Low quantity and quality of anti-spike humoral response is linked to CD4 T-cell apoptosis in COVID-19 patients. Cell Death and Differentiation. 2022
- T cell apoptosis characterizes severe Covid-19 disease. Cell Death and Differentiation. 2022
- Dysregulation of glycerophospholipid metabolism during Behçet's disease contributes to a pro-inflammatory phenotype of circulating monocytes. Emerging Microbes & Infections. 2021
- Genetics in the Host- Mycobacterium ulcerans interaction. Immunological Reviews. 2021
- Interleukin-6 Is a Biomarker for the Development of Fatal Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia. Frontiers in Immunology. 2021
- Individual and clinical variables associated with the risk of Buruli ulcer acquisition: A systematic review and meta-analysis. PLoS Neglected Tropical Diseases. 2020
- Building an innovative Medical School in Portugal: the experience of the University of Minho. FEM: Revista de la Fundación Educación Médica. 2017
- Analysis of a Local HIV-1 Epidemic in Portugal Highlights Established Transmission of Non-B and Non-G Subtypes. J. Clin. Microbiol.. 2015
- Detecting antibody-labeled BCG MNPs using a magnetoresistive biosensor and magnetic labeling technique. Journal of Nano Research. 2015
- Follow-up of the first case of Mycobacterium ulcerans infection documented by PCR, genotyping and culture in the Republic of Congo-Brazzaville | Suivi du premier cas d'infection à Mycobacterium ulcerans confirmé par culture, PCR et génotypage en République du Congo-Brazzaville. Medecine Tropicale. 2008
- Aquatic insects and Mycobacterium ulcerans: An association relevant to buruli ulcer control?. PLoS Medicine. 2007
- Cutting Edge: IFN-¿ Regulates the Induction and Expansion of IL-17-Producing CD4 T Cells during Mycobacterial Infection. Journal of Immunology. 2006
- Differences in resistance of C57BL/6 and C57BL/10 mice to infection by Mycobacterium avium are independent of gamma interferon. Infection and Immunity. 2000
- Neutrophils play a protective nonphagocytic role in systemic Mycobacterium tuberculosis infection of mice. Infection and Immunity. 2000
- Therapeutic efficacy of liposomal rifabutin in a Mycobacterium avium model of infection. Antimicrobial Agents and Chemotherapy. 2000
- Effects of iron deprivation on Mycobacterium avium growth. Tubercle and Lung Disease. 1999
- Cytokines involved in resistance to Mycobacterium avium in a mouse model of infection. Medical Principles and Practice. 1997
- Erratum: Role of gamma interferon and tumor necrosis factor alpha during T-cell-independent and -dependent phases of Mycobacterium avium infection (Infection and Immunity 62:9 (3969)). Infection and Immunity. 1995
- Susceptibility of beige mice to Mycobacterium avium: Role of neutrophils. Infection and Immunity. 1995
- Characterization of the virulence of Mycobacterium avium complex (MAC) isolates in mice. Clinical and Experimental Immunology. 1994
- Role of gamma interferon and tumor necrosis factor alpha during T-cell- independent and -dependent phases of Mycobacterium avium infection. Infection and Immunity. 1994
- Role of interleukin-6 in the induction of protective T cells during mycobacterial infections in mice. Immunology. 1994
- Induction and expression of protective T cells during Mycobacterium avium infections in mice. Clinical and Experimental Immunology. 1992
- Host and bacterial factors control the Mycobacterium avium-induced chronic peritoneal granulocytosis in mice. Clinical and Experimental Immunology. 1991
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artigo de revista
- Development of an antibiotics delivery system for topical treatment of the neglected tropical disease Buruli ulcer. International Journal of Applied Pharmaceutics. 2022
- Purification and Characterization of a Thrombolytic Enzyme Produced by a New Strain of Bacillus subtil. Journal of Microbiology and Biotechnology. 2021
- Increasing the potential of cell-penetrating peptides for cancer therapy using a new pentagonal scaffold. European Journal of Pharmacology. 2019
- Antimicrobial activity of Mycobacteriophage D29 Lysin B during Mycobacterium ulcerans infection. PLoS Neglected Tropical Diseases. 2019
- K2 Capsule Depolymerase Is Highly Stable, Is Refractory to Resistance, and Protects Larvae and Mice from Acinetobacter baumannii Sepsis. Applied and Environmental Microbiology. 2019
- Development of Inhalable Superparamagnetic Iron Oxide Nanoparticles (SPIONs) in Microparticulate System for Antituberculosis Drug Delivery. Advanced Healthcare Materials. 2018
- Exploring inhalable polymeric dry powders for anti-tuberculosis drug delivery. Journal of Nanoparticle Research. 2018
- Immune-evasion Strategies of Mycobacteria and Their Implications for the Protective Immune Response. Current Issues in Molecular Biology. 2018
- Natural based eumelanin nanoparticles functionalization and preliminary evaluation as carrier for gentamicin. Reactive and Functional Polymers. 2017
- Preparation and biological evaluation of ethionamide-mesoporous silicon nanoparticles against Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry Letters. 2017
- Building an innovative Medical School in Portugal: the experience of the University of Minho. FEM: Revista de la Fundación Educación Médica. 2017
- Genetic Variation in Autophagy-Related Genes Influences the Risk and Phenotype of Buruli Ulcer. PLoS Neglected Tropical Diseases. 2016
- Delivery of LLKKK18 loaded into self-assembling hyaluronic acid nanogel for tuberculosis treatment. Journal of Controlled Release. 2016
- Spontaneous Healing of Mycobacterium ulcerans Lesions in the Guinea Pig Model. PLoS Neglected Tropical Diseases. 2015
- IL-17A Promotes Intracellular Growth of Mycobacterium by Inhibiting Apoptosis of Infected Macrophages. Frontiers in Immunology. 2015
- Clinical Epidemiology of Buruli Ulcer from Benin (2005-2013): Effect of Time-Delay to Diagnosis on Clinical Forms and Severe Phenotypes. PLoS Neglected Tropical Diseases. 2015
- Analysis of a Local HIV-1 Epidemic in Portugal Highlights Established Transmission of non-B and -G Subtypes. Journal of Clinical Microbiology. 2015
- BCG vaccination-induced long-lasting control of Mycobacterium tuberculosis correlates with the accumulation of a novel population of CD4<sup>+</sup>IL-17<sup>+</sup>TNF<sup>+</sup>IL-2<sup>+</sup> T cells. Vaccine. 2015
- Detecting antibody-labeled BCG MNPs using a magnetoresistive biosensor and magnetic labeling technique. Journal of Nano Research. 2015
- Proteomic Analysis of the Action of the Mycobacterium ulcerans Toxin Mycolactone: Targeting Host Cells Cytoskeleton and Collagen. PLoS Neglected Tropical Diseases. 2014
- Differential post-transcriptional regulation of IL-10 by TLR2 and TLR4-activated macrophages. European Journal of Immunology. 2014
- Mycobacterium tuberculosis Strains Are Differentially Recognized by TLRs with an Impact on the Immune Response. Antibiotics. 2013
- Phage Therapy Is Effective against Infection by Mycobacterium ulcerans in a Murine Footpad Model. PLoS Neglected Tropical Diseases. 2013
- Evidence for Diversifying Selection in a Set of Mycobacterium tuberculosis Genes in Response to Antibiotic- and Nonantibiotic-Related Pressure. Molecular Biology and Evolution. 2013
- P. brasiliensis Virulence Is Affected by SconC, the Negative Regulator of Inorganic Sulfur Assimilation. Antibiotics. 2013
- TLR9 Activation Dampens the Early Inflammatory Response to Paracoccidioides brasiliensis, Impacting Host Survival. PLoS Neglected Tropical Diseases. 2013
- Update on the challenging role of biofilms in peritoneal dialysis. Antibiotics. 2013
- Corticosteroid-Induced Immunosuppression Ultimately Does Not Compromise the Efficacy of Antibiotherapy in Murine Mycobacterium ulcerans Infection. PLoS Neglected Tropical Diseases. 2012
- Cellular Immunity Confers Transient Protection in Experimental Buruli Ulcer following BCG or Mycolactone-Negative Mycobacterium ulcerans Vaccination. Antibiotics. 2012
- Local and Regional Re-Establishment of Cellular Immunity during Curative Antibiotherapy of Murine Mycobacterium ulcerans Infection. Antibiotics. 2012
- The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma. Genes and Immunity. 2012
- The C Allele of rs5743836 Polymorphism in the Human TLR9 Promoter Links IL-6 and TLR9 Up-Regulation and Confers Increased B-Cell Proliferation. Antibiotics. 2011
- Mycobacterium ulcerans Triggers T-Cell Immunity followed by Local and Regional but Not Systemic Immunosuppression. Infection and Immunity. 2011
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TLR2 deficiency by compromising p19 (IL-23) expression limits T
h 17 cell responses to Mycobacterium tuberculosis. International Immunology. 2011 - The selective COX-2 inhibitor Etoricoxib reduces acute inflammatory markers in a model of neurogenic laryngitis but loses its efficacy with prolonged treatment. Inflammation Research. 2010
- Influenza Infectious Dose May Explain the High Mortality of the Second and Third Wave of 1918–1919 Influenza Pandemic. Antibiotics. 2010
- Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection with Mycobacterium tuberculosis. Journal of Experimental Medicine. 2010
- Response to Treatment in a Prospective Cohort of Patients with Large Ulcerated Lesions Suspected to Be Buruli Ulcer (Mycobacterium ulcerans Disease). PLoS Neglected Tropical Diseases. 2010
- Dextrin nanoparticles: Studies on the interaction with murine macrophages and blood clearance. Colloids and Surfaces B: Biointerfaces. 2010
- IFN-g–Dependent Activation of Macrophages during Experimental Infections by Mycobacterium ulcerans Is Impaired by the Toxin Mycolactone. Journal of Immunology. 2010
- Virulence attenuation of Candida albicans genetic variants isolated from a patient with a recurrent bloodstream infection. Antibiotics. 2010
- Buruli ulcer disease: Prospects for a vaccine. Medical Microbiology and Immunology. 2009
- Fine-Needle Aspiration, an Efficient Sampling Technique for Bacteriological Diagnosis of Nonulcerative Buruli Ulcer. Journal of Clinical Microbiology. 2009
- Pathogenetic mechanisms of the intracellular parasite Mycobacterium ulcerans leading to Buruli ulcer. Lancet Infectious Diseases. 2009
- New Foci of Buruli Ulcer, Angola and Democratic Republic of Congo. Emerging Infectious Diseases. 2008
- Developments on Drug Delivery Systems for the Treatment of Mycobacterial Infections. Current Topics in Medicinal Chemistry. 2008
- Suivi du premier cas d’infection à Mycobacterium Ulcerans confirmé par culture, PCR et Génotypage en République Du Congo-Brazzaville 2008
- First Cultivation and Characterization of Mycobacterium ulcerans from the Environment. PLoS Neglected Tropical Diseases. 2008
- A New Model of Laryngitis: Neuropeptide, Cyclooxygenase, and Cytokine Profile. Laryngoscope. 2008
- IL-10 modulates depressive-like behavior. Journal of Psychiatric Research. 2008
- Rifabutin encapsulated in liposomes exhibits increased therapeutic activity in a model of disseminated tuberculosis. International Journal of Antimicrobial Agents. 2008
- Mycolactone-Mediated Inhibition of Tumor Necrosis Factor Production by Macrophages Infected withMycobacterium ulceransHas Implications for the Control of Infection. Infection and Immunity. 2007
- Evidence for an Intramacrophage Growth Phase ofMycobacterium ulcerans. Infection and Immunity. 2007
- Cutting edge: IFN-γ regulates the induction and expansion of IL-17-producing CD4 T cells during mycobacterial infection. The Journal of Immunology. 2006
- Infection with Mycobacterium ulcerans Induces Persistent Inflammatory Responses in Mice. Infection and Immunity. 2005
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capítulo de livro
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documento
- Bacteriophage depolymerases: evolutionary insights and antivirulence strategies against bacterial pathogens 2020
- Erratum for Oliveira et al., "K2 Capsule Depolymerase Is Highly Stable, Is Refractory to Resistance, and Protects Larvae and Mice from Acinetobacter baumannii Sepsis". Applied and Environmental Microbiology. 2020
- Novel capsular depolymerases-based strategy to kill multidrug-resistant pathogenic bacteria 2019
- Bacteriophage-depolymerases: their diversity and therapeutic properties 2019
- Delivery of nanogel formulations with antimicrobial peptides for the treatment of mycobacteriosis 2017
- Antimicrobial peptide-loaded hyaluronic acid-based formulations, method of production and uses thereof 2017
- Targeting macrophages with inhalable microparticulate system for the treatment of tuberculosis 2017
- Student success and perception of subject knowledge of an integrated course on the essentials of disease and treatment 2016
- Biomedical applications of human cathelicidin 2015
- Learning bacterial identification in infectious disease using a laboratory guided discovery approach 2015
- IL-10 mediates susceptibility to Listeria monocytogenes infection by modulating the accumulation and differentiation of CD11b+ Ly6C+ monocytes 2014
- Delivery of antimicrobial peptides for the treatment of mycobacteriosis 2014
- Innovative anti-microbial strategies against buruli ulcer : bacteriophage therapy 2013
- Experimental phage therapy against Mycobacterium ulcerans in mice model 2012
- Characterisation by molecular biology and MALDI-TOF ICMS of zygomycete Gongronella sp. isolated from an Alentejo vineyard soil 2011