publicações selecionadas
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artigo académico
- Combinatorial therapies for spinal cord injury: Strategies to induce regeneration. Neural Regeneration Research. 2019
- The cell secretome in personalized and regenerative medicine.. Biochimie. 2018
- Immunomodulation as a neuroprotective strategy after spinal cord injury. Neural Regeneration Research. 2018
- Development of marine-based nanocomposite scaffolds for biomedical applications. International Review of Neurobiology. 2012
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artigo de conferência
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artigo de revista
- Neurodifferentiation and Neuroprotection Potential of Mesenchymal Stromal Cell-Derived Secretome Produced in Different Dynamic Systems. Biomedicines. 2023
- The Central Nervous System Source Modulates Microglia Function and Morphology In Vitro. International Journal of Molecular Sciences. 2023
- Cerebral Malaria Model Applying Human Brain Organoids. Cells. 2023
- Revolutionizing Disease Modeling: The Emergence of Organoids in Cellular Systems. Cells. 2023
- Pathophysiology and Therapeutic Approaches for Spinal Cord Injury. International Journal of Molecular Sciences. 2022
- Enhanced neuronal differentiation by dynamic piezoelectric stimulation. Journal of Biomedical Materials Research. 2022
- Intrathecal Injection of the Secretome from ALS Motor Neurons Regulated for miR-124 Expression Prevents Disease Outcomes in SOD1-G93A Mice. Biomedicines. 2022
- Immunomodulatory and regenerative effects of the full and fractioned adipose tissue derived stem cells secretome in spinal cord injury. Experimental Neurology. 2022
- Pre-conditioning with IFN-γ and hypoxia enhances the angiogenic potential of iPSC-Derived MSC secretome 2022
- Preclinical Assessment of Mesenchymal-Stem-Cell-Based Therapies in Spinocerebellar Ataxia Type 3. Biomedicines. 2021
- Unilateral Intrastriatal 6-Hydroxydopamine Lesion in Mice: A Closer Look into Non-Motor Phenotype and Glial Response. International Journal of Molecular Sciences. 2021
- Fractionating stem cells secretome for Parkinson's disease modeling: Is it the whole better than the sum of its parts?. Biochimie. 2021
- Electroactive Smart Materials for Neural Tissue Regeneration. ACS Applied Bio Materials. 2021
- Citalopram Administration Does Not Promote Function or Histological Recovery after Spinal Cord Injury. International Journal of Molecular Sciences. 2020
- Impact of Aging on the 6-OHDA-Induced Rat Model of Parkinson’s Disease. International Journal of Molecular Sciences. 2020
- Cell Secretome: Basic Insights and Therapeutic Opportunities for CNS Disorders. Pharmaceuticals. 2020
- Preclinical Comparison of Stem Cells Secretome and Levodopa Application in a 6-Hydroxydopamine Rat Model of Parkinson’s Disease. Cells. 2020
- Bone Marrow Mesenchymal Stem Cells' Secretome Exerts Neuroprotective Effects in a Parkinson's Disease Rat Model. Frontiers in Bioengineering and Biotechnology. 2019
- Extremely low frequency magnetic field induces human neuronal differentiation through NMDA receptor activation. Journal of Neural Transmission. 2019
- Filling the Gap: Neural Stem Cells as A Promising Therapy for Spinal Cord Injury. Pharmaceuticals. 2019
- Mesenchymal Stem Cells-derived Exosomes: A New Possible Therapeutic Strategy for Parkinson’s Disease?. Cells. 2019
- Generation of an induced pluripotent stem cell line (CSC-46) from a patient with Parkinson's disease carrying a novel p.R301C mutation in the GBA gene. Stem Cell Research. 2019
- Trait determinants of impulsive behavior: a comprehensive analysis of 188 rats. Acta Cytologica. 2018
- Cell secretome based approaches in Parkinson's disease regenerative medicine. Expert Opinion on Biological Therapy. 2018
- Secretome of Undifferentiated Neural Progenitor Cells Induces Histological and Motor Improvements in a Rat Model of Parkinson's Disease. Stem Cells Translational Medicine. 2018
- The impact of Mesenchymal Stem Cells and their secretome as a treatment for gliomas.. Biochimie. 2018
- Co-Transplantation of Adipose Tissue-Derived Stromal Cells and Olfactory Ensheathing Cells for Spinal Cord Injury Repair. Stem Cells. 2018
- Exploiting the impact of the secretome of MSCs isolated from different tissue sources on neuronal differentiation and axonal growth. Biochimie. 2018
- Generation of an induced pluripotent stem cell line (CSC-41) from a Parkinson's disease patient carrying a p.G2019S mutation in the LRRK2 gene. Stem Cell Research. 2018
- Generation of an integration-free induced pluripotent stem cell line (CSC-43J) from a patient with sporadic Parkinson's disease. Stem Cell Research. 2018
- Influence of passage number on the impact of the secretome of adipose tissue stem cells on neural survival, neurodifferentiation and axonal growth. Biochimie. 2018
- Mesenchymal Stem Cell Secretome Improves Tendon Cell Viability In Vitro and Tendon-Bone Healing In Vivo When a Tissue Engineering Strategy Is Used in a Rat Model of Chronic Massive Rotator Cuff Tear. American Journal of Sports Medicine. 2018
- Safinamide: a new hope for Parkinson's disease?. Drug Discovery Today. 2018
- The Role of Biomaterials as Angiogenic Modulators of Spinal Cord Injury: Mimetics of the Spinal Cord, Cell and Angiogenic Factor Delivery Agents. Frontiers in Pharmacology. 2018
- αvβ3 and α5β1 integrin-specific ligands: From tumor angiogenesis inhibitors to vascularization promoters in regenerative medicine?. Biotechnology Advances. 2018
- Systemic Interleukin-4 Administration after Spinal Cord Injury Modulates Inflammation and Promotes Neuroprotection. Pharmaceuticals. 2017
- Crosstalk between glial and glioblastoma cells triggers the "go-or-grow" phenotype of tumor cells. Cell Communication and Signaling. 2017
- Impact of mesenchymal stem cells' secretome on glioblastoma pathophysiology. Journal of Translational Medicine. 2017
- Mesenchymal Stem Cell Secretome. American Journal of Sports Medicine. 2017
- Reverse shoulder arthroplasty for irreparable massive rotator cuff tears: a systematic review with meta-analysis and meta-regression. Journal of Shoulder and Elbow Surgery. 2017
- Arthroscopic and open repair of massive rotator cuff tears have similar results: a systematic review. Journal of ISAKOS. 2017
- Effect of Levodopa on Reward and Impulsivity in a Rat Model of Parkinson's Disease. Acta Cytologica. 2017
- Impact of the Secretome of Human Mesenchymal Stem Cells on Brain Structure and Animal Behavior in a Rat Model of Parkinson's Disease. Stem Cells Translational Medicine. 2017
- Influence of Different ECM-Like Hydrogels on Neurite Outgrowth Induced by Adipose Tissue-Derived Stem Cells. Stem Cells International. 2017
- Mesenchymal stem cells secretome-induced axonal outgrowth is mediated by BDNF. Acta Cytologica. 2017
- Old and new challenges in Parkinson's disease therapeutics. Acta Cytologica. 2017
- Bioengineered cell culture systems of central nervous system injury and disease. Drug Discovery Today. 2016
- Combination of a peptide-modified gellan gum hydrogel with cell therapy in a lumbar spinal cord injury animal model. Biomaterials. 2016
- Combining neuroprotective agents: effect of riluzole and magnesium in a rat model of thoracic spinal cord injury. Spine Journal. 2016
- Erratum: Multifunctionalized CMCht/PAMAM Dendrimer Nanoparticles Modulate the Cellular Uptake by Astrocytes and Oligodendrocytes in Primary Cultures of Glial Cells (Macromolecular Bioscience (2012) 12 (591-597) DOI: 10.1002/mabi.201100294). Acta Biomaterialia. 2016
- MSCs-Derived Exosomes: Cell-Secreted Nanovesicles with Regenerative Potential. Frontiers in Pharmacology. 2016
- Modulation of the Mesenchymal Stem Cell Secretome Using Computer-Controlled Bioreactors: Impact on Neuronal Cell Proliferation, Survival and Differentiation. Acta Cytologica. 2016
- Unveiling the Differences of Secretome of Human Bone Marrow Mesenchymal Stem Cells, Adipose Tissue-Derived Stem Cells, and Human Umbilical Cord Perivascular Cells: A Proteomic Analysis. Stem Cells and Development. 2016
- Combinatorial activity of flavonoids with antibiotics against drug resistant Staphylococcus aureus. Microbial Drug Resistance. 2015
- Induction of neurite outgrowth in 3D hydrogel-based environments. Biomedical Materials. 2015
- Mesenchymal stem cells secretome as a modulator of the neurogenic niche: Basic insights and therapeutic opportunities. Frontiers in Cellular Neuroscience. 2015
- Secretome of Mesenchymal Progenitors from the Umbilical Cord Acts as Modulator of Neural/Glial Proliferation and Differentiation. Stem Cell Reviews and Reports. 2015
- Animal model for chronic massive rotator cuff tear: behavioural and histologic analysis. Knee Surg Sports Traumatol Arthrosc. 2015
- Do hypoxia/normoxia culturing conditions change the neuroregulatory profile of Wharton Jelly mesenchymal stem cell secretome?. Stem Cell Research and Therapy. 2015
- Failure of Y-27632 to improve the culture of adult human adipose-derived stem cells. Stem Cells and Cloning: Advances and Applications. 2015
- Hierarchical scaffolds enhance osteogenic differentiation of human Wharton's jelly derived stem cells. Biofabrication. 2015
- Hydrogels and Cell Based Therapies in Spinal Cord Injury Regeneration. Stem Cells International. 2015
- Evaluation of the best method to assess antibiotic potentiation by phytochemicals against staphylococcus aureus. Diagnostic Microbiology and Infectious Disease. 2014
- Evaluation of the effects of selected phytochemicals on quorum sensing inhibition and in vitro cytotoxicity. Antibiotics. 2014
- From basics to clinical: A comprehensive review on spinal cord injury. Elife. 2014
- In vitro evaluation of cell-seeded chitosan films for peripheral nerve tissue engineering. Tissue Engineering. Part C: Methods. 2014
- The Secretome of Bone Marrow and Wharton Jelly Derived Mesenchymal Stem Cells Induces Differentiation and Neurite Outgrowth in SH-SY5Y Cells.. Stem Cells International. 2014
- Microglia Response and In Vivo Therapeutic Potential of Methylprednisolone-Loaded Dendrimer Nanoparticles in Spinal Cord Injury. Small. 2013
- Benefits of Spine Stabilization with Biodegradable Scaffolds in Spinal Cord Injured Rats. Tissue Engineering. Part C: Methods. 2013
- Behavioral characterization of the 6-hydroxidopamine model of Parkinson's disease and pharmacological rescuing of non-motor deficits. Molecular Neurodegeneration. 2013
- Chitosan tubes of varying degrees of acetylation for bridging peripheral nerve defects. Biomaterials. 2013
- Combining adult stem cells and olfactory ensheathing cells: The secretome effect. Stem Cells and Development. 2013
- Combining adult stem cells and olfactory ensheating cells : the secretome effect. Stem Cells and Development. 2013
- De novo bone formation on macro/microporous silk and silk/nano-sized calcium phosphate scaffolds. Journal of Bioactive and Compatible Polymers. 2013
- Development and Characterization of a PHB-HV-based 3D Scaffold for a Tissue Engineering and Cell-therapy Combinatorial Approach for Spinal Cord Injury Regeneration. Acta Biomaterialia. 2013
- In vitro evaluation of the cytotoxicity and cellular uptake of CMCht/PAMAM dendrimer nanoparticles by glioblastoma cell models. Journal of Nanoparticle Research. 2013
- Mesenchymal stem cells secretome: A new paradigm for central nervous system regeneration?. Cellular and Molecular Life Sciences. 2013
- Modulation of bone marrow mesenchymal stem cell secretome by ECM-like hydrogels. Biochimie. 2013
- Rodent models of Parkinson's disease: Beyond the motor symptomatology. Acta Cytologica. 2013
- Unveiling the effects of the secretome of mesenchymal progenitors from the umbilical cord in different neuronal cell populations. Biochimie. 2013
- Development and characterization of a novel hybrid tissue engineering–based scaffold for spinal cord injury repair. Tissue Engineering. Part C: Methods. 2012
- Angiogenic Potential of Gellan-Gum-Based Hydrogels for Application in Nucleus Pulposus Regeneration: In Vivo Study. International Review of Neurobiology. 2012
- Interactions between Schwann and olfactory ensheathing cells with a starch/polycaprolactone scaffold aimed at spinal cord injury repair. Journal of Biomedical Materials Research. 2012
- Peripheral mineralization of a 3D biodegradable tubular construct as a way to enhance guidance stabilization in spinal cord injury regeneration. Journal of Materials Science. 2012
- The effects of peptide modified gellan gum and olfactory ensheathing glia cells on neural stem/progenitor cell fate. Biomaterials. 2012
- The secretome of stem cells isolated from the adipose tissue and Wharton jelly acts differently on central nervous system derived cell populations. Stem Cell Research and Therapy. 2012
- Development of Gellan Gum-Based Microparticles/Hydrogel Matrices for Application in the Intervertebral Disc Regeneration. Tissue Engineering. Part C: Methods. 2011
- In vivo biodistribution of carboxymethylchitosan/poly(amidoamine) dendrimer nanoparticles in rats. Journal of Bioactive and Compatible Polymers. 2011
- Mesenchymal stem cells in the umbilical cord : phenotypic characterization, secretome and applications in central nervous system regenerative medicine. Current Stem Cell Research & Therapy. 2011
- Microchannel-patterned and heparin micro-contact-printed biodegradable composite membranes for tissue-engineering applications. International Review of Neurobiology. 2011
- The secretome of bone marrow mesenchymal stem cells-conditioned media varies with time and drives a distinct effect on mature neurons and glial cells (primary cultures). International Review of Neurobiology. 2011
- Carboxymethylchitosan/Poly(amidoamine) Dendrimer Nanoparticles in Central Nervous Systems-Regenerative Medicine: Effects on Neuron/Glial Cell Viability and Internalization Efficiency. Acta Biomaterialia. 2010
- Adipose tissue derived stem cells secretome: Soluble factors and their roles in regenerative medicine. Current Stem Cell Research & Therapy. 2010
- Dendrimers and derivatives as a potential therapeutic tool in regenerative medicine strategies - A review. Progress in Polymer Science. 2010
- Development and characterization of a novel hybrid tissue engineering-based scaffold for spinal cord injury repair. Tissue Engineering. Part C: Methods. 2010
- Role of human umbilical cord mesenchymal progenitors conditioned media in neuronal/glial cell densities, viability, and proliferation. Stem Cells and Development. 2010
- Effects of Starch/ Polycaprolactone-based Blends for Spinal Cord Injury Regeneration in Neurons/Glial Cells Viability and Proliferation. Journal of Bioactive and Compatible Polymers. 2009
- Adhesion, proliferation, and osteogenic differentiation of a mouse mesenchymal stem cell line (BMC9) seeded on novel melt-based chitosan/polyester 3D porous scaffolds. Tissue Engineering - Part A.. 2008
- Assessment of the suitability of chitosan/polybutylene succinate scaffolds seeded with mouse mesenchymal progenitor cells for a cartilage tissue engineering approach. Tissue Engineering - Part A.. 2008
- In vivo response to starch-based scaffolds designed for bone tissue engineering applications. Journal of Biomedical Materials Research. 2007
- Adult stem cells in bone and cartilage tissue engineering. Current Stem Cell Research & Therapy. 2006
- Biological response to pre-mineralized starch based scaffolds for bone tissue engineering. Journal of Materials Science. 2005
- Nano- and micro-fiber combined scaffolds: A new architecture for bone tissue engineering. Journal of Materials Science. 2005
- Bone tissue engineering: State of the art and future trends. Acta Biomaterialia. 2004
- Multichannel mould processing of 3D structures from microporous coralline hydroxyapatite granules and chitosan support materials for guided tissue regeneration/engineering. Journal of Materials Science. 2004
- Novel Starch-Based Scaffolds for Bone Tissue Engineering: Cytotoxicity, Cell Culture, and Protein Expression. Tissue Engineering. Part C: Methods. 2004
- Osteogenic induction of human bone marrow-derived mesenchymal progenitor cells in novel synthetic polymer-hydrogel matrices. Tissue Engineering. Part C: Methods. 2003
- Preliminary study on the adhesion and proliferation of human osteoblasts on starch-based scaffolds. Journal of Nanoparticle Research. 2002
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capítulo de livro
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documento
- Mesenchymal stem cells secretome: current trends and future challenges. Neural Regeneration Research. 2020
- Stem cells: microenvironment, micro/nanotechnology, and application. Stem Cells International. 2015
- Functional gellan gum hydrogels and cell based therapies – A novel therapeutic approach for spinal cord injury regeneration. International Review of Neurobiology. 2014
- Secretome of mesenchymal stem cells as a new tool for central nervous system regenerative medicine. International Review of Neurobiology. 2014
- Secretome of mesenchymal stem/stromal cells in regenerative medicine. Biochimie. 2013
- Regeneration strategies in the central nervous system: drug-loaded nanoparticles for spinal cord injury regeneration 2013
- Intracellular delivery of methylprednisolone by dendrimer-based nanoparticles improves locomotor outcomes after spinal cord injury. International Review of Neurobiology. 2012
- Biodistribution and preliminary therapeutic potential of CMCht/PAMAM dendrimer nanoparticles administration in rats 2012
- Hyaluronic acid/poly(amidoamine) dendrimer nanoparticles for central nervous system applications: in vitro and in vivo studies. International Review of Neurobiology. 2012
- Using the secretome of mesenchymal progenitors of the umbilical cord as a modulator of neural and glial survival, viability and differentiation. International Review of Neurobiology. 2012
- BIOHYBRID – Biohybrid templates for peripheral nerve regeneration. Journal of the Peripheral Nervous System. 2012
- Editorial: Adult stem cells and tissue engineering in central nervous system regenerative medicine. Current Stem Cell Research & Therapy. 2011
- A comparative study on the effects of adipose tissue derived and bone marrow mesenchymal stem cells on neurons/glial cells viability, proliferation and differentiation. International Review of Neurobiology. 2008
- In vitro characterization on the interactions between carboxymethyl-chitosan/poly(amidoamine) dendrimer nanoparticles and neurons/glial cells. International Review of Neurobiology. 2008
- Role of paracrine factors released by mesenchymal progenitors from the umbilical cord in neurons/glial cell viability, proliferation and differentiation. International Review of Neurobiology. 2008
- Starch/gellan gum hybrid 3D guidance systems for spinal cord injury regeneration: Scaffolds processing, characterization and biological evaluation. International Review of Neurobiology. 2008
- The data base of the filamentous fungi culture collection at Minho University (MUM) 2000
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livro
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poster de conferência