publicações selecionadas
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artigo académico
- A Simple Protocol for the Synthesis of Perylene Bisimides from Perylene Tetracarboxylic Dianhydride. Nanoscale. 2024
- Discovery of 2,9-diaryl-6-carbamoylpurines as a novel class of antitubercular agents. European Journal of Medicinal Chemistry. 2024
- Poly(lactic acid) composites with few layer graphene produced by noncovalent chemistry. E-Polymers. 2022
- Imidazolylpyrrolone-Based Small Molecules as Anticancer Agents for Renal Cell Carcinoma. Chemistry - A European Journal. 2022
- Regioselective Synthesis of 2-Aryl-5-cyano-1-(2-hydroxyaryl)-1H-imidazole-4-carboxamides Self-Assisted by a 2-Hydroxyaryl Group. ACS Omega, 2022, 7, 27, 23289–23301. 2022
- Simple routes for the functionalization of carbon nanoparticles and potencial applications. Boletin del Grupo Espanol del Carbon. 2019
- Few-layer graphene aqueous suspensions for polyurethane composite coatings. MRS Advances. 2017
- Biological Importance of Structurally Diversified Chromenes. European Journal of Medicinal Chemistry. 2016
- ChemInform Abstract: Reactivity and Regioselectivity in the Acylation of 2,4-Diaminoquinazolines.. ChemInform. 2016
- ChemInform Abstract: Acid Catalyzed Synthesis of 2-(2-Aminophenyl)quinazoline-4-amine and Reaction with Aromatic Aldehydes.. ChemInform. 2016
- Synthesis of 3-aminochromenes: The Zincke reaction revisited. Tetrahedron. 2014
- ChemInform Abstract: Tandem Cyclization of a Bispyridinium Chloride: Facile Synthesis of Substituted Indolizines.. ChemInform. 2014
- Tandem Cyclization of a Bispyridinium Chloride: Facile Synthesis of Substituted Indolizines. Synlett. 2013
- A one-pot synthesis of substituted pyrido[2,3-b]indolizines. Tetrahedron. 2011
- A simple and eco-friendly approach for the synthesis of 2-imino and 2-oxo-2H-chromene-3-carboxamides. Green Chemistry. 2008
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artigo de conferência
- Characterization of organic matter at different stages of a composting process 2019
- Comparison of cadmium binding by humic and fulvic acids extracted from two composts of different origin 2019
- Influence of the feedstock material on the compost maturity, stability and reactivity 2019
- Advanced Electrically Conductive Adhesives for High Complexity PCB Assembl. AIP Conference Proceedings. 2017
- Functionalization of CNTS with maleic anhydride 2012
- The diels-alder cycloaddition reaction of 1,3-butadiene to MWCNTs 2011
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artigo de revista
- Regioselective synthesis of 2-Aryl-5-cyano-1-(2-hydroxyaryl)-1H-imidazole-4-carboxamides self-assisted by a 2-Hydroxyaryl group. ACS Omega. 2022
- Selective Cytotoxicity of Portuguese Propolis Ethyl Acetate Fraction towards Renal Cancer Cells. Biomolecules. 2022
- Unravelling the anticancer potential of functionalized chromeno[2,3-b]pyridines for breast cancer treatment. Bioorganic Chemistry. 2020
- A Convenient One-pot Synthesis of Chromenyl Acrylates and Acrylonitriles. Synlett. 2020
- Synthesis of 2-(aminophenyl)adenine derivatives: a simple protocol using the classical iron powder/acetic acid reduction methodology. Canadian Journal of Chemistry. 2020
- Inhibitory Effect of 5-Aminoimidazole-4-Carbohydrazonamides Derivatives Against Candida spp. Biofilm on Nanohydroxyapatite Substrate. Mycopathologia. 2019
- A Simple Method for Anchoring Silver and Copper Nanoparticles on Single Wall Carbon Nanotubes. Nanomaterials. 2019
- 2-Aryladenine derivatives as a potent scaffold for A1, A3 and dual A1/A3 adenosine receptor antagonists: Synthesis and structure-activity relationships. Bioorganic & Medicinal Chemistry. 2019
- Phenolic Imidazole Derivatives with Dual Antioxidant/Antifungal Activity: Synthesis and Structure-Activity Relationship. Medicinal Chemistry. 2019
- New Nitrogen Compounds Coupled to Phenolic Units with Antioxidant and Antifungal Activities: Synthesis and Structure¿Activity Relationship.. Biomolecules. 2018
- Exploitation of New Chalcones and 4H-chromenes as Agents for Cancer Treatment. European Journal of Medicinal Chemistry. 2018
- Adenine Derivatives: Promising Candidates for Breast Cancer Treatment. European Journal of Organic Chemistry. 2018
- Water Dispersible Few-Layer Graphene Stabilized by a Novel Pyrene Derivative at Micromolar Concentration. Nanomaterials. 2018
- Biological importance of structurally diversified chromenes. European Journal of Medicinal Chemistry. 2016
- Role of Carbonaceous Fragments on the Functionalization and Electrochemistry of Carbon Materials. Chemelectrochem. 2016
- Reactivity and regioselectivity in the acylation of 2,4-diaminoquinazolines. Tetrahedron. 2016
- Acid catalyzed synthesis of 2-(2-aminophenyl)quinazoline-4-amine and reaction with aromatic aldehydes. Nanoscale. 2016
- Grafting of adipic anhydride to carbon nanotubes through a Diels-Alder cycloaddition/ oxidation cascade reaction. Carbon. 2016
- The reaction of 2-(acylamino)benzonitriles with primary aromatic amines: A convenient synthesis of 2-substituted 4-(arylamino)quinazolines. Synthesis. 2015
- Self-Assembled Functionalized Graphene Nanoribbons from Carbon Nanotubes. Chemistryopen. 2015
- Enhanced electrochemical sensing of polyphenols by oxygen-mediated surface. Nanoscale. 2015
- Novel structurally similar chromene derivatives with opposing effects on p53 and apoptosis mechanisms in colorectal HCT116 cancer cells. European Journal of Pharmaceutical Sciences. 2015
- Probing the surface of oxidized carbon nanotubes by selective interaction with target molecules. Electrochemistry Communications. 2015
- Synthesis and antimicrobial activity of novel 5-aminoimidazole-4-carboxamidrazones. Bioorganic & Medicinal Chemistry Letters. 2014
- Proteomic Analysis of the Action of the Mycobacterium ulcerans Toxin Mycolactone: Targeting Host Cells Cytoskeleton and Collagen. PLoS Neglected Tropical Diseases. 2014
- 6-Carbohydrazonamidepurines: Convenient precursors for 4,8-disubstituted pyrimido[5,4-d]pyrimidines. Synlett. 2014
- Synthesis and radical scavenging activity of phenol-imidazole conjugates. Bioorganic & Medicinal Chemistry Letters. 2014
- The solvent effect on the sidewall functionalization of multi-walled carbon nanotubes with maleic anhydride. Carbon. 2014
- Efficient Dispersion of Multi-walled Carbon Nanotubes in Aqueous Solution by Non-covalent Interaction with Perylene Bisimides. Nanoscale. 2013
- N1- and C6-substituted adenines: A regioselective and efficient synthesis. Tetrahedron. 2013
- General synthetic approach to 2-phenolic adenine derivatives. Synlett. 2012
- Synthesis and electrochemical evaluation of substituted imidazo[4,5-d]pyrrolo[3,2-f][1,3] diazepine scaffolds. Tetrahedron. 2012
- Synthesis of 4-amino-3,5-dicyano-arylpyrazoles, part 2: Isolation and characterization of by-products. Synthetic Communications. 2012
- One-Pot regioselective synthesis of 2,6,9-trisubstituted adenines. Synlett. 2011
- Versatile synthesis of 5-aminoimidazole-4-carboxylic acid derivatives. Synlett. 2011
- A facile one-pot synthesis of 3-imidazolyl 1,2,4-triazoles and 1,2,4-oxa-diazolones. Synlett. 2010
- Controlled Functionalization of Carbon Nanotubes by a Solvent-free Multicomponent Approach. ACS Nano. 2010
- IFN-g–Dependent Activation of Macrophages during Experimental Infections by Mycobacterium ulcerans Is Impaired by the Toxin Mycolactone. Journal of Immunology. 2010
- Organic Functionalization of Carbon Nanofibers for Composite Applications. E-Polymers. 2010
- Synthesis and in vitro evaluation of substituted pyrimido[5,4-d]pyrimidines as a novel class of Antimycobacterium tuberculosis agents. European Journal of Medicinal Chemistry. 2010
- Unzipping of Functionalized Multiwall Carbon Nanotubes Induced by STM. Nano Letters. 2010
- Unzipping of Functionalized Multiwall Carbon Nanotubes Induced by STM. Nano Letters. 2010
- A mild approach to the synthesis of 4-amino-8-(arylamino)pyrimido[5,4-d] pyrimidine 3-oxides. European Journal of Organic Chemistry. 2009
- Identification of novel scaffolds from an original chemical library as potential antipsychotics. Qsar & Combinatorial Science. 2009
- Novel nitrogen compounds enhance protection and repair of oxidative DNA damage in a neuronal cell model: Comparison with quercetin. Chemico-Biological Interactions. 2009
- Quantification of humic acids in surface water: Effects of divalent cations, pH, and filtration]. Journal of Environmental Monitoring. 2009
- Synthesis and in vitro activity of 6-amino-2,9-diarylpurines for Mycobacterium tuberculosis. Tetrahedron. 2009
- The Diels-Alder Cycloaddition Reaction in the Functionalization of Carbon Nanofibers. Journal of Biomedical Nanotechnology. 2009
- The Condensation of Salicylaldehydes and Malononitrile Revisited: Synthesis of New Dimeric Chromene Derivatives. Journal of Organic Chemistry. 2008
- Protective role of new nitrogen compounds on ROS/RNS-mediated damage to PC12 cells. Free Radical Research. 2008
- Antifungal activity of a novel chromene dimer. Journal of Industrial Microbiology & Biotechnology. 2007
- Functionalization of carbon nanofibers by 1,3 - dipolar cycloaddition reactions and its effect on composite properties. Composites Science and Technology. 2007
- Functionalization of carbon nanofibers by a Diels-Aider addition reaction. Journal of Biomedical Nanotechnology. 2007
- The 1,3-dipolar cycloaddition reaction in the functionalization of carbon nanofibers. Journal of Biomedical Nanotechnology. 2007
- Oxidative stress protection by newly synthesized nitrogen compounds with pharmacological potential. Life Sciences. 2006
- Synthesis of novel derivatives of 4-amino-3,5-dicyanopyrazole. Journal of Chemical Research. 2004
- Efficient conversion of 6-cyanopurines into 6-alkoxyformimidoyl-purines. Organic and Biomolecular Chemistry. 2004
- Synthesis of novel 6-enaminopurines. Organic and Biomolecular Chemistry. 2004
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capítulo de livro
- 4.2. 3.6. A Simple and Ecological Preparation of a Chromene-3-carboxamide Derivative 2017
- Synthesis of azachrysenes and multi-nitrogenated derivatives. Targets in Heterocyclic Systems. 2016
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documento
- Synthesis of imidazo-pyridines/diazepines and evaluation of their anticancer potential in renal cell carcinoma cell lines 2023
- New imidazole based scaffolds for the treatment of renal cell carcinoma 2023
- New imidazole derivatives as anticancer agents for the treatment of renal cell carcinoma 2023
- Studies on the acylation reaction of salicylaldehyde 2022
- Chromen[2,3-b]pyridines: synthesis and evaluation of the anticancer potential for breast cancer treatment 2022
- Studies on the synthesis of new heterocycles based on the chromene and purine nucleus 2022
- New substituted 3,5-dihydro-4H-chromeno [2,3-d] pyrimidin-4-one: a promising strategy for breast cancer treatment 2020
- Avaliação da capacidade de composto produzido industrialmente para remoção de paracetamol de águas 2019
- Comparison of cadmium binding by humic and fulvic acids extracted from compost samples of different feedstock 2019
- Chromene derivatives: a new strategy to overcome renal cancer resistance 2019
- Chromene derivatives: a new strategy to overcome renal cancer resistance. 2019
- Exploitation of novel chromene derivatives for breast cancer treatment 2019
- Synthesis and biological activity of new anticancer agents for breast cancer treatment 2019
- Exploitation of novel chromene derivatives for breast cancer treatment. 2019
- New molecules based on chromene moiety as candidates for renal cell carcinoma therapy 2019
- Novas moléculas baseadas na unidade de cromeno como candidatas à terapia do carcinoma das células renais (CCR). 2019
- Síntese e atividade biológica de novos agentes anticancerígenos para o tratamento do cancro da mama. 2019
- New chromene derivatives: Unraveling the molecular mechanisms for breast cancer therapy 2019
- Chromene-based compounds as candidates for renal cell cancer treatment 2019
- Chromene-based compounds as candidates for renal cell cancer treatment. 2019
- Synthesis of functionalized chromeno[2,3-b]pyridines: promising agents for breast cancer treatment 2019
- Biological activity of novel targeted inhibitors for renal cell cancer therapy 2019
- Biological activity of novel targeted inhibitors for renal cell cancer therapy. 2019
- In vitro and in vivo evaluation of new chromene derivatives as potent anticancer agents 2019
- In vitro and in vivo evaluation of new chromene derivatives as potent anticancer agents. 2019
- Synthesis of functionalized chromeno[2,3-b]pyridines: promising agents for breast cancer treatment. 2019
- Chromene-based molecules as targeted inhibitors for renal cell cancer therapy 2019
- Chromene-based molecules as targeted inhibitors for renal cell cancer therapy. 2019
- New chromene-based molecules as microtubule destabilizers and pro-apoptotic agents in cancer 2018
- Chemical and biological characterization of chalcones and 4H-chromenes: exploitation as anticancer agents 2018
- Chemical and biological characterization of chalcones and 4H-chromenes: exploitation as anticancer agents. 2018
- Unraveling the anticancer molecular mechanisms of new chromene-based drugs 2018
- Discovery of chromene-based molecules as apoptosis-inducers by G2/M cell-arrest 2018
- Discovery of chromene-based molecules as apoptosis-inducers by G2/M cell-arrest. 2018
- Unraveling the anticancer molecular mechanisms of new chromene-based drugs. 2018
- Chromene-based drug candidates for cancer treatment 2018
- Chromene-based drug candidates for cancer treatment. 2018
- New chromene-based drug candidates for cancer treatment 2017
- Novel alpha-hydrazononitriles from 4-cyanoformimidoyl-5-aminoimidazoles and hydrazines: characterization and isomerization 2016
- Utilização de fragmentos carbonáceos obtidos a partir nanotubos de carbono em sensores eletroquímicos 2016
- Chemical approaches to elucidate the structure-activity relationship of the 5-amino-N'-substituted-imidazole-4-carbohydrazonamides as antifungal agents 2016
- Chromene derivatives as anticancer agents: synthesis and biological evaluation 2016
- Chromene derivatives as anticancer agents: synthesis and biological evaluation. 2016
- The synthesis of new 5-aminoimidazoles as potential antifungal agents 2016
- A new and efficient synthesis of N3-cycloalkylamino-6,8-diaminopurines 2015
- A novel and efficient approach to new N3-substituted-6,8-diaminopurines 2015
- Antifungal action of three (Z)-5-amino-N'-aryl-1-methyl-1H-imidazole-4-carbohydrazonamides 2015
- The synthesis of new 6-hydrazinopurines as potential anticancer agents 2015
- The synthesis of novel 5-aminoimidazoles derivatives with anticancer activity 2015
- 4,8-Disubstituted pyrimido[5,4-d]pyrimidines as novel apoptotic independent anticancer agents: synthesis and in vitro activity against HCT116 human colon cancer cells 2015
- A new and efficient synthesis of benzoimidazopurine derivatives 2015
- Anticancer profile of a selection of new chromene-based compounds 2015
- New pyrimido[5,4-d]pyrimidines with enhanced anticancer activity on colorectal cancer cells: synthesis, SAR study and mechanism of action 2015
- Reactivity of 3-pyridinium coumarins with carbon nucleophiles 2015
- Synthesis and anticancer activity of N3-substituted-6,8-diaminopurines 2015
- Synthesis of new 9-(4´-RO-phenyl)-6-cyanopurine derivatives 2015
- Action of three (Z)-5-amino-N'-aryl-1-methyl-1H-imidazole-4-carbohydrazonamides on mitochondrial activity of Candida sp. and its effect in NO production 2014
- Action of three (Z)-5-amino-N'-aryl-1-methyl-1H-imidazole4-carbohydrazonamides on mitochondrial activity of Candida 2014
- High in vitro activity of synthetic 5-aminoimidazole-4-carboxamidrazones against Candida biofilms formation on nanohydroxyapatite 2014
- High in vitro activity of synthetic 5-aminoimidazole-4-carboxamidrazones against Candida biofilms formation on nanohydroxyapatite 2014
- Characterization of new 5-aminoimidazole derivatives 2014
- NMR Characterization of new 2,6- and 6,8-diaminopurines 2014
- Comportamento voltamétrico de perilenos bismides modificados em GCE e SPE 2014
- Electrochemical sensing using carboxylated multiwalled carbon nanotubes 2014
- Evaluation of the antioxidant activity of a new family of phenolic compounds by voltammetric methods 2014
- Non-covalent modification of voltammetric SPE sensors 2014
- Simple strategies for stable aqueous suspensions of carbon nanotubes 2014
- Electrochemical evaluation of the antioxidant capacity of hydroxylated benzylideneamino imidazole derivatives 2014
- Graphene nanoribbons and nanoflakes from functionalized carbon precursors 2014
- Heat-Treatments for carbon ativation of comercial screen printed electrodes 2014
- Novel structurally similar chromene derivatives with opposing effects on p53 and apoptosis mechanisms in colorectal HCT116 cancer cells 2014
- New phenolic imidazole derivatives: evaluation of antioxidant activity 2013
- Regiospecific Synthesis of N-Substituted 2-Oxopurine-6- carboxamidines 2013
- Screen Printed Electrodes Modified with Carboxylated Multiwall Carbon Nanotubes for the Analysis of Hydroquinone and Ascorbic Acid 2013
- Synthesis of 6-(N-methyl)carboxamidino-2-oxopurines as Potential Antimycobacterial Agents 2013
- Evaluation of the antioxidant activity of new phenolic imidazole derivatives by cyclic voltammetry 2013
- Synthesis of new pyrimido[5,4-d]pyrimidines derivatives as potential antitubercular agents 2013
- A new simple and efficient synthesis of imidazolil benzimidazoles 2013
- A novel and efficient approach to the synthesis of 2,6-diaminopurines 2013
- A novel and facile synthetic approach to N9-substituted guanines 2013
- Polymer composites with graphene nanoribbons formed by the unzipping of carbon nanotubes 2013
- Regiospecific synthesis of N-substituted 2-oxopurine-6-carboxamidines 2013
- Some reactions of active methylene compounds with 2-hydroxychalcones 2013
- Synthesis and anticancer activity of 6-aryl Adenines 2013
- Synthesis and antimicrobial activity of 5-Aminoimidazoles incorporating N-Phenylhydrazonoyl moiety 2013
- Synthesis and antimicrobial activity of 5-Aminoimidazoles incorporating a substituted N-Phenyl amidrazonoyl moiety 2013
- Synthesis of 6-(N-methyl)carboxamidino-2-oxopurines as potential antimycobacterial agents 2013
- The synthesis of 2-aryl-hypoxanthines: a novel and efficient synthetic approach 2013
- Synthesis and antimicrobial activity of cianoformimidoyl imidazoles incorporating a N-Phenyl hydrazhydrazonoyl moiety 2012
- Synthesis of 4-amidinoimidazoles incorporating a cyanamide moiety : novel precursors for biologically important purines 2012
- Synthesis of 4-amidinoimidazoles incorporating a cyanamide moiety: novel precursors for biologically important purines 2012
- Electrochemical investigation of substituted 4,4’-biimidazole scaffolds as anticancer drug candidates 2012
- Synthesis and characterization of a copper(II) complex of a substituted bi-imidazole 2012
- Utilização de métodos eletroquímicos para o estudo de compostos com potencial atividade anticancerígena 2012
- Electrochemical evaluation of new anticancer drug candidates 2012
- 6-Amidinopurines as convenient precursors to pyrimido[5,4-d]pyrimidines for sar studies on Mycobacterium tuberculosis 2012
- A new simple and efficient synthesis of 6-aryladenines 2012
- A novel and efficient approach to 2-amino-6-cyanopurines 2012
- An efficient synthesis of 1,2,4-triazoles analogs with potencial biological activity 2012
- An efficient synthetic approach to 6-triazolopurines 2012
- Antioxidant/pro-oxidant properties of phenolic imidazole derivatives 2012
- Formation of graphene nanoribbons in solution 2012
- Functionalization of CNTS with maleic anhydride 2012
- Graphene nanoribbons from carbon nanotubes 2012
- Synthesis and anticancer activity of 2,6,9-trisubstituted adenines 2012
- Synthesis and anticancer activity of novel chromeno-imidazo[1,2-a]pyridines 2012
- Synthesis and antimicrobial activity of 2,9-diarylpurines 2012
- Synthesis and antimicrobial activity of 4-(N-aryl)cyanoformimidoyl imidazoles 2012
- Synthesis and antimicrobial activity of cyanoformimidoyl imidazoles incorporating a N-phenylhydrazonoyl moiety 2012
- Synthesis and antimycobacterial activity of 2-oxopurines 2012
- Synthesis and pharmacological evaluation of new chromene scaffolds for adenosine receptors 2012
- Synthesis of 1-(2-imino-2H-chromen-3-yl)pyridinium chloride derivatives as potential anticancer agents 2012
- Synthesis of 9-methyl-6-methylamino-2-arylpurines as potential new ligands to adenosine receptors 2012
- Synthesis of new chromene derivatives as potencial anticancer agents 2012
- Synthesis of novel 6-benzylaminopurine derivatives 2012
- The efficient and regioselective synthesis of N1-aryl isoguanines: A mechanistic approach 2012
- 6-Cyanopurines: versatile reagents to generate potentially bioactive compounds 2011
- Synthesis of 6-amino or 6-carbamoylpurines for SAR studies on adenosine receptors 2011
- Synthesis of new 6-carboximidamide purines with potential biological activity 2011
- 2-Phenolic-purines: synthesis and antioxidant activity 2011
- The diels-alder cycloaddition reaction of 1,3-butadiene to MWCNTs 2011
- The regioselective synthesis of 2,6,9-trisubstituted adenines: a mechanistic approach 2011
- The synthesis of [1,2,4]-triazolo[5,1-i]purines : two competitive reaction pathways 2011
- The synthesis of isoguanines and pyrroles from a common imidazole intermediate 2011
- N-Methyl piperazine: an important fragment for interaction with serotonine 5-HT2a receptors 2010
- New scaffold for adenosine receptors 2010
- Characterisation and catalytic activity of copper(II) complexes with chromene derivatives 2009
- Synthesis of 12H-chromeno[2´,3´:4,5]imidazo[1,2-a]pyridine by a base catalysed cascade cyclisation approach 2009
- Synthesis of aryl piperazine derivatives as potential antipsychotics 2009
- A simple and eco-friendly approach for the synthesis of 2-imino-2H-chromene-3-carboxamides 2008
- Nitrogen compounds as protectors of oxidative damage induced in H9c2 myoblasts 2008
- Oxidative DNA damage protection and repair by new synthetic compounds 2008
- Synthesis and in vitro antifungal activity of a novel chromene derivative 2007
- Some Reactions of (2-amino-3-cyano-4H-chromen-4-yl)malononiytile 2006
- The Condensation of Aromatic Aldehydes and Malononitrile Revisited 2006
- The Reaction of 2-Oxo-2H-chromene-3-carbonitrile with 2-Methoxyethylamine 2006
- New synthetic compounds as inhibitors of mycotoxin synthesis 2005
- Antioxidant activity of phenol incorporated in nitrogen-containing compounds 2004
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poster de conferência
- An efficient method for dehydration of 6-carbamoylpurines 2017
- Reactivity of 6-imidatopurines with benzylhydrazine 2017
- Synthesis and biological activity against Mycobacterium tuberculosis of 2,3-dihydroadenine derivatives 2017
- Synthesis and in vitro activity in HCT116 human colon cancer cells of new 4-substituted-pyrimido[5,4-d]pyrimidine derivatives 2015
- Synthesis and in vitro activity in HCT116 human colon cancer cells of new phenol-pyrimido[5,4-d]pyrimidine conjugates 2015