publicações selecionadas
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artigo académico
- A transcriptomic profiling reveals novel roles of Cadherin-3 in metabolic programming of glioblastoma 2024
- A transcriptomic profiling reveals novel roles of Cadherin-3 in metabolic programming of glioblastoma - in final phase of preparation 2024
- Emerging roles and biomarker potential of WNT6 in human cancers. Theranostics. 2024
- Exploring Glioma Heterogeneity: Integrative Multi-Omics Analysis to Discover Transcriptome-Methylome signatures 2024
- Updating TCGA glioma subtype classification through integration of molecular profiling data following 2016 and 2021 WHO guidelines 2024
- WNT6 drives mechanisms of aggressiveness and resistance to chemotherapy in human glioblastoma - in final phase of preparation 2024
- Effects of Lactate Transport Inhibition by AZD3965 in Muscle-Invasive Urothelial Bladder Cancer. Pharmaceutics. 2023
- Epigenetically-regulated miR-30a/c-5p directly target TWF1 and hamper ccRCC cell aggressiveness. Translational Research. 2022
- Cadherin-3 is a novel oncogenic biomarker with prognostic value in glioblastoma. Molecular Oncology. 2022
- Chronic Stress Does Not Influence the Survival of Mouse Models of Glioblastoma. Frontiers in Oncology. 2022
- Cadherin switches during epithelial-mesenchymal transition: CDH4/RCAD downregulation reduces bladder cancer progression. Cellular Oncology. 2022
- Fucoidan/chitosan nanoparticles functionalized with anti-ErbB-2 target breast cancer cells and impair tumor growth in vivo. International Journal of Applied Pharmaceutics. 2021
- A novel molecular link between HOXA9 and WNT6 in glioblastoma identifies a subgroup of patients with particular poor prognosis. Molecular Oncology. 2020
- MicroRNA-30a-5pme: a novel diagnostic and prognostic biomarker for clear cell renal cell carcinoma in tissue and urine samples. Journal of Experimental & Clinical Cancer Research. 2020
- HOX gene cluster (de)regulation in brain: from neurodevelopment to malignant glial tumours. Cellular and Molecular Life Sciences. 2020
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artigo de revista
- Glucose Metabolism Reprogramming in Bladder Cancer: Hexokinase 2 (HK2) as Prognostic Biomarker and Target for Bladder Cancer Therapy. Cancers. 2023
- MCT1 Is a New Prognostic Biomarker and Its Therapeutic Inhibition Boosts Response to Temozolomide in Human Glioblastoma. Cancers. 2021
- Intracellular Autofluorescence as a New Biomarker for Cancer Stem Cells in Glioblastoma. Cancers. 2021
- Exploiting the Complexities of Glioblastoma Stem Cells: Insights for Cancer Initiation and Therapeutic Targeting. International Journal of Molecular Sciences. 2020
- Unravelling the anticancer potential of functionalized chromeno[2,3-b]pyridines for breast cancer treatment. Bioorganic Chemistry. 2020
- Sirtuins' Deregulation in Bladder Cancer: SIRT7 Is Implicated in Tumor Progression through Epithelial to Mesenchymal Transition Promotion. Cancers. 2020
- Overexpression of circulating MiR-30b-5p identifies advanced breast cancer. Journal of Translational Medicine. 2019
- WNT6 is a novel oncogenic prognostic biomarker in human glioblastoma. Theranostics. 2018
- A multiplatform approach identifies miR-152-3p as a common epigenetically regulated onco-suppressor in prostate cancer targeting TMEM97. Clinical Epigenetics. 2018
- The long non-coding RNA HOTAIR is transcriptionally activated by HOXA9 and is an independent prognostic marker in patients with malignant glioma. Oncotarget. 2018
- SETDB2 and RIOX2 are differentially expressed among renal cell tumor subtypes, associating with prognosis and metastization. Epigenetics. 2017
- Effects of the functional HOTAIR rs920778 and rs12826786 genetic variants in glioma susceptibility and patient prognosis. Journal of Neuro-Oncology. 2017
- Histone methyltransferase PRMT6 plays an oncogenic role of in prostate cancer. Oncotarget. 2016
- Expression of histone methyltransferases as novel biomarkers for renal cell tumor diagnosis and prognostication. Epigenetics. 2015
- Transcriptional profiling of HOXA9-regulated genes in human glioblastoma cell models. Genomics Data. 2015
- MicroRNA-375 plays a dual role in prostate carcinogenesis. Clinical Epigenetics. 2015
- Impact of TGF-ß1 -509C/T and 869T/C polymorphisms on glioma risk and patient prognosis. Tumor Biology. 2015
- A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide. Oncotarget. 2015
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capítulo de livro
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documento
- Deciphering WNT6-driven mechanisms of aggressiveness and resistance to chemotherapy in human glioblastoma 2024
- Deciphering novel mechanisms of WNT6-driven chemotherapy resistance in human glioblastoma 2023
- Chromene-based molecules: privileged scaffold for oncology drug development 2023
- Effects of lactate transport inhibition by AZD3965 in muscle-invasive urothelial bladder cancer 2023
- Synthesis of chromene[2,3-b]pyridines and characterization of their anticancer potential for the treatment of breast cancer 2023
- Síntese de cromeno[2,3-b]piridinas e caracterização do seu potencial anticancerígeno para o tratamento do cancro da mama 2023
- Treatment of triple-negative breast cancer through externally triggered target-less drug carriers 2023
- A transcriptomic profiling reveals novel roles of Cadherin-3 in metabolic programming of glioblastoma 2023
- Unveiling the impact of the oncogenic molecule Cadherin-3 in the metabolism of human glioblastoma 2023
- Unveiling the impact of the oncogenic molecule Cadherin-3 in themetabolism of human glioblastoma 2023
- Farmacologia pré-clínica do inibidor do transportador de monocarboxilatos 1, AZD3965, no cancro da bexiga 2022
- Role of the ubiquitin hydrolase ATXN3 in glioblastoma: a new tumor suppressor gene? 2022
- Hexokinase II (HKII) as prognostic biomarker and target for bladder cancer therapy 2022
- Concerted metabolic and transcriptomic rewiring dictates gliioblastoma cells survival and stemness 2022
- Cadherin-3 is a novel oncogenic biomarker with prognostic value in glioblastoma 2022
- GPR81 in Bladder Cancer - Functional Insights 2022
- Pre-clinical pharmacology of the monocarboxylate transporter 1 inhibitor AZD3965 in bladder cancer 2022
- A new lead compound for triple negative breast cancer therapy 2021
- A new therapeutic option for triple negative breast cancer 2021
- Hexokinase II (HKII) is a prognostic biomarker for bladder cancer patients: Antitumoral activity of the HKII inhibitor 2-deoxy-D-glucose 2021
- EMT impact in bladder cancer progression: understanding the cadherins' role and their regulatory mechanisms 2021
- Upregulation of Hexokinase II (HKII) impacts survival of bladder cancer patients: Effects of HKII inhibition by 2-deoxy-D-glucose 2021
- Characterization of the biological activity of functionalized chromeno[2,3-b]pyridines for breast cancer treatment 2020
- Characterization of the biological activity of functionalized chromeno[2,3b]pyridines for breast cancer treatment 2020
- CDH3/P-cadherin is a novel oncogenic biomarker with prognostic value in glioblastoma 2020
- Deciphering WNT6 up and down roads in glioblastoma: mechanistic, functional, and clinical insight 2020
- New chromene derivatives: unravelling the molecular mechanisms for breast cancer treatment 2019
- Functional and prognostic relevance of CDH3/P-cadherin in glioblastoma 2019
- WNT6 is a novel oncogenic prognostic biomarker in human glioblastoma 2019
- Deciphering key roles of WNT6 in glioblastoma: mechanistic, functional, and clinical insights 2019
- PO-473 Wnt6 expression in glioblastoma: mechanistic, functional and clinical implications 2018
- CDH3/P-cadherin expression is associated with aggressiveness of human glioblastoma 2018
- CDH3/P-cadherin as a novel biomarker in glioblastoma: functional and prognostic insights 2018
- WNT6 is a novel oncogenic prognostic biomarker in human glioblastoma 2018
- Functional impact and prognostic relevance of CDH3/P-cadherin in glioblastoma 2018
- PO-105 Cdh3/p-cadherin as a novel biomarker in glioblastoma: functional and prognostic insights 2018
- Intracellular autofluorescence: a new biomarker for Glioblastoma Stem Cells 2017
- WNT6 regulation in Glioblastoma: Mechanistic, Functional and Clinical implications 2017
- CDH3/P-cadherin as a putative HOXA9 target in gliomas: functional and clinical relevance 2017
- Intracellular autofluorescence: a new biomarker for Glioblastoma Stem Cells” 2017
- Regulation of WNT6 by HOXA9 in glioblastoma: functional and clinical relevance 2016
- A Transcriptomic Signature Mediated by HOXA9 Sustains Human Glioblastoma Aggressiveness and Resistance to Chemotherapy 2015
- HOXA9-mediated activation of the WNT pathway: functional and clinical relevance in glioblastoma 2015
- Impact of TGF-ß1 -509C/T and 869T/C polymorphisms on glioma risk and patient prognosis 2015
- A Transcriptomic Signature Mediated by HOXA9 Promotes Human Glioblastoma Initiation, Aggressiveness and Resistance to Temozolomide 2015
- HOTAIR is transcriptionally activated by HOXA9 and is an independent prognostic marker in patients with malignant glioma 2014
- HOXA9 promotes glioblastoma initiation, aggressiveness and resistance to therapy 2014
- Regulation of Wnt Signaling by HOXA9 in Glioblastoma: Mechanistic and Prognostic Insights 2014
- WNT6 promoter methylation associates with its expression in glioblastoma 2014
- A Transcriptomic Signature Mediated by HOXA9 Sustains Human Glioblastoma Aggressiveness, Resistance to Chemotherapy and Glioma Initiation 2013
- HOXA9 Promotes Glioma Initiation and Sustains Human Glioblastoma Aggressiveness and Resistance to Therapy 2013
- Long Non-Coding RNA HOTAIR is Transcriptionally Activated by HOXA9 and Is Associated with Poor Prognosis in Glioblastoma. 2013
- Regulation of Wnt signaling by HOXA9 in Glioblastoma: Mechanistic and Prognostic Insights 2013
- Relevance of HES1 expression in human gliomas: molecular and clinical correlates 2013
- Regulation of WNT signaling by HOXA9 in glioblastoma: mechanistic, prognostic and therapeutic insights 2013
- Long Non-Coding RNA HOTAIR is Transcriptionally Activated by HOXA9 and Is Associated with Poor Prognosis in Glioblastoma 2013
- HOXA9 target genes in Glioblastoma: characterization and clinical relevance 2012
- Regulation of WNT6 expression by HOXA9 in glioblastoma and prognostic implications 2012
- HOXA9 transcriptome analysis in Glioblastoma: The bioinformatics beyond the bench 2012
- Enantioselective diels-alder methodology in the synthesis of (-)-1-azafagomine 2010
- Updating TCGA glioma classification through integration of molecular profiling data following the 2016 and 2021 WHO guidelines
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teses
- Deciphering key roles of WNT6 in glioblastoma: mechanistic, functional, and clinical insights 2018
- Regulation of Wnt signaling by HOXA9 in Glioblastoma: Mechanistic, prognostic and therapeutic insights 2013
- The Transcriptome of the Oncogenic HOXA9 Homeoprotein in Human Glioblastoma: Functional and Clinical Relevance 2013