publicações selecionadas
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artigo académico
- Bioadhesive Hyaluronic Acid-Based Hydrogels for Spinal Cord Injury. Biomacromolecules. 2024
- Biocompatible 3D-Printed Tendon/Ligament Scaffolds Based on Polylactic Acid/Graphite Nanoplatelet Composites. Nanomaterials. 2023
- Synthesis of new hetero-arylidene-9(10H)-anthrone derivatives and their biological evaluation. Bioorganic Chemistry. 2020
- N-Heterocyclic Olefin Catalysis for the Ring Opening of Cyclic Amidine Compounds: A Pathway to the Synthesis of e-Caprolactam- and ¿-Lactam-Derived Amines. Journal of Organic Chemistry. 2019
- (R )-Metacycloprodigiosin-HCl: Chiroptical properties and structure. Chirality. 2018
- Synthesis, Cytotoxicity Evaluation in Human Cell Lines and in Vitro DNA Interaction of a Hetero-Arylidene-9(10H )-Anthrone. European Journal of Organic Chemistry. 2018
- NavMol 3.0: enabling the representation of metabolic reactions by blind users. Bioinformatics. 2017
- Developments in the Reactivity of 2-Methylimidazolium Salts. Journal of Organic Chemistry. 2017
- New cholinesterase inhibitors for Alzheimer's disease: Structure Activity Studies (SARs) and molecular docking of isoquinolone and azepanone derivatives. Bioorganic Chemistry. 2016
- A catalytic route to dibenzodiazepines involving Buchwald-Hartwig coupling: Reaction scope and mechanistic consideration. Nanoscale. 2015
- Transition-metal-catalyzed intramolecular cyclization of amido(hetero)arylboronic acid aldehydes to isoquinolinones and derivatives. Nanoscale. 2015
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Regiocontrolled S
N Ar reaction on 2,3-dihalopyridines with NaSMe to obtain bromo(methylthio)pyridines as key precursors of 3-halo-2-(hetero) arylthieno[2,3- b ]pyridines and thieno[3,2- b ]pyridines. Synthesis. 2013
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artigo de conferência
- 2D Spatial Audio in a Molecular Navigator/Editor for Blind and Visually Impaired Users 2017
- New Di(hetero)arylethers and Di(hetero)arylamines in the Thieno [3,2-b]pyridine Series: Synthesis, Growth Inhibitory Activity on Human Tumor Cell Lines and Nanotumor Cells, Effects on Cell Cycle And on Apoptosis 2014
- Synthesis, molecular docking and biological Evaluation of New 1-Aryl-3-[3-(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas as Potent Type II CEGFR-2 Tyrosine Kinase Inhibitors 2014
- Fluorescence studies on new potential antitumoral 1,3-diarylurea derivatives in the thieno[3,2-b]pyridine series encapsulated in magnetoliposomes 2012
- Fluorescence studies on new potential antitumoral 1,3-diarylurea derivatives of thieno[3,2-b]pyridines in solution and in nanoliposomes 2011
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artigo de revista
- Adhesive and Antibacterial Films Based on Marine-Derived Fucoidan and Chitosan. ACS Sustainable Chemistry and Engineering. 2022
- Adhesive and biodegradable membranes made of sustainable catechol-functionalized marine collagen and chitosan. Colloids and Surfaces B: Biointerfaces. 2022
- A poly-e-caprolactone based biofilm carrier for nitrate removal from water. Amino Acids. 2016
- A poly-e-caprolactone based biofilm carrier for nitrate removal from water. Amino Acids. 2016
- Antioxidant activity of aminodiarylamines in the thieno[3,2-b]pyridine series: Radical scavenging activity, lipid peroxidation inhibition and redox profile. Journal of Enzyme Inhibition and Medicinal Chemistry. 2014
- New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: Synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death. European Journal of Medicinal Chemistry. 2013
- New 1,3-diarylureas linked by C-C Suzuki coupling to the methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate moiety: synthesis and fluorescence studies in solution and in lipid membranes. Journal of Photochemistry and Photobiology A-Chemistry. 2013
- 1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modelling Studies. Biomed Research International. 2013
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Synthesis of 2-(hetero)arylthieno[2,3-b] or [3,2-b]pyridines from 2,3-dihalopyridines, (hetero)arylalkynes, and Na
2 S. Further functionalizations. Tetrahedron. 2012 - New potential antitumoral di(hetero)arylether derivatives in the thieno[3,2-b]pyridine series : synthesis and fluorescence studies in solution and in nanoliposomes. Journal of Photochemistry and Photobiology A-Chemistry. 2012
- Aminodi(hetero)arylamines in the Thieno[3,2-b]pyridine Series: Synthesis, Effects in Human Tumor Cells Growth, Cell Cycle Analysis, Apoptosis and Evaluation of Toxicity Using Non-Tumor Cells. Biomolecules. 2012
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documento
- Adhesive and biodegradable membranes from marine origin raw materials for soft tissue engineering 2023
- Adhesive and antibacterial membranes from marine-derived fucoidan and chitosan 2022
- Bioadhesive hydrogels based on Hyaluronic acid for spinal cord regeneration 2022
- Chitosan hydrogels Inspired by mussels with superior adhesion for bone tissue regeneration 2022
- Hydrogels based on catechol-modified hyaluronic acid combined with graphene derivatives for biomedical applications 2021
- Injectable thermosensitive catechol-modified chitosan hydrogels with superior adhesion for bone tissue regeneration 2021
- Marine origin membranes based on chitosan and collagen 2021
- Production and characterization of tissue adhesives for Gastrointestinal repair 2019
- Production of tissue adhesives based on marine-derived materials for Gastrointestinal repair 2019
- A straightforward approach to olodaterol synthesis applying the asymmetric Henry reaction 2019
- New e-Caprolactam and ¿-Lactam-Derived Amines as acetylcholinesterase inhibitors 2019
- Synthesis of New Hetero-Arylidene-9(10H)-Anthrone Derivatives and Biological Evaluation as Antiproliferative Agents 2019
- Synthesis and mechanistic studies of hetero arylidene-9(10H)-anthrone 2018
- Pathway to the synthesis of 1,3-diamines a high value added compound 2017
- NavMol 2.2s – A software for navigation and editing of molecular formulas for blinds and visually impaired users 2016
- A Novel Catalytic Route to Dibenzodiazepines involving Buchwald-Hartwig Coupling 2015
- Synthesis of a Library of Isoquinolinones and Azepinones Derivatives using a Metal-Catalyzed Intramolecular Cyclization Reaction as the kep step 2015
- The role of cholinesterases in Alzheimer’s disease: screening of target compounds 2015
- Antioxidant and antimicrobial activities of arylamides-acetals derivatives: potencial drugs for neurodegenerative diseases 2014
- Computational study for the palladium-catalyzed dibenzodiazepine synthesis 2014
- Catalytic Borylation/Intramolecular Arylation as a Novel Approach to Rasagline Derivatives 2014
- New Chiral Analogues for Neurodegenerative Diseases: The power of metal catalysis 2014
- Versatile Innovative Metal Catalyzed Couplings - Modular Approach to Rasagiline Analogues 2014
- CIA -Catalytic Intramolecular Arylation - Studies at Controlling the Ring Size 2014
- Synthesis, molecular Docking and biological evaluation of new 1-Aryl-3-[3-(thieno[3,2-b]pyridin-7-ylthio)phenylureas as Potent Type II VEGFR-2 Tyrosine Kinase inhibitors 2014
- BoImAr: Borylation(Catalytic)-Imination-Arylation(Catalytic) - A New Synthetic Approach to Promising Alzheimer and Parkinson Drugs 2013
- Antioxidant and Antifungival activities of halogenated arlamide-acetals: patential drugs for neurodegenerative diseades 2013
- New di(hetero)arylthioethers 1,3-diarylureas in the thieno[3,2-b]pyridine series as VEGFR2 tyrosine kinase Inhibitors: docking, synthesis, enzymatic and cellular assays 2013
- Synthesis of 3-halo-2-(hetero)arylthienopyridine derivatives as key precursors of potential antitumorals 2013
- Synthesis of new n-[3-(thieno[3,2-b]pyridine-7-ylthio)phenyl]benzamides as potential inhibitors of VEGFR2 using rational design 2013
- INMOLFARM – Nova família de fármacos para doenças neurodegenerativas 2013
- Synthesis, docking, enzymatic and cellular assays of thieno[3,2-b]pyridine-thioether-1,3-diarylureas as VEGFR2 inhibitors 2013
- Synthesis, growth inhibitory activity on human tumor cell lines and evaluation of the hepatotoxicity of di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series 2013
- Thieno[3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on human tumor cell lines 2013
- Heteroarylether 1,3-diarylureas in the thieno[3,2-d]pyrimidine series as VEGFR2 tyrosine kinase inhibitors: synthesis, docking studies, enzymatic and cellular assays 2013
- Synthesis of thienopyridine derivatives as potential antitumorals and/or antiangiogenics 2013
- BolmAr: Borylation(Catalytic)-Imination-Arylation (Catalytic) ¿ A New Synthetic Approach to Promising Alzheimer and Parkinson Drugs 2013
- Epidermal growth factor receptor inhibitory activity of new potential antitumor di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series 2013
- New di(heteroaryl)thioethers 1,3-diarylureas in the thieno[3,2-b]pyridine series as VEGFR2 tyrosine kinase inhibitors: docking, synthesis, enzymatic and cellular assays 2013
- Synthesis and evaluation of the antitumor potential of new aminated or methoxylated di(hetero)arylthioethers in the thieno[3,2-b]pyridine series 2013
- Synthesis of new N-[3-(thieno[3,2-b]pyridine-7-ylthio)phenyl]benzamides as potential inhibitors the tyrosine kinase domain of VEGFR2 2013
- 1-Aryl-3-[4-(thieno[3,2-b]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 inhibitors: synthesis, docking, enzumatic and celular assays 2012
- Synthesis, growth inhibitory activity on human tumor cell lines and evaluation of the hepatotoxicity of di(hétero)arylethers and di(hétero)arylamines in the thieno[3,2-b]pyridine series 2012
- 1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 inhibitors: synthesis, docking enzymatic and cellular assays 2012
- Synthesis of novel 1-ary-3-[2-, 3- or 4-(thieno[3,2-b]pyridin-7-ylyhio)phenyl]ureas and evaluation as VEGFR2 tyrosine kinase inhibitors 2012
- Synthesis of thienopyridine derivatives as potential antitumorals and/or antiangiogenics 2012
- Thieno [3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on human tumor cell lines 2012
- Synthesis of tetracyclic systems and (thio)ureas from aminodi(hetero)arylamines in the thieno[3,2-b]pyridine series 2012
- Synthesis of 3-Halo-2-(hetero)arylthienopyridines through a tree-step methodology from 2,3-dihalopyridines, methanethiolate, (hetero)arylalkynes and electrophiles 2012
- Synthesis of di(hetreo)arylamines and ethers in the thieno[3,2-b]pyridine series by metal-catalyzed couplings 2012
- Heteroarylether 1,3-diarylureas in the thieno[3,2-d]pyrimidine series as VEGFR2 tyrosine Kinase inhibitors: Synthesis, docking studies, enzymatic and cellular assays 2012
- Fluorescence studies on new potential antitumoral 1,3-diarylurea derivatives in the thieno[3,2-b]pyridine series encapsulated in magnetoliposomes 2012
- Synthesis, growth inhibitory activity on human tumor cell lines and evaluation of the hepatotoxicity of di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series. 2012
- 1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 tyrosine kinase inhibitors: synthesis, docking studies, enzymatic and cellular assays 2012
- 1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 tyrosine kinase inhibitors: synthesis, docking, studies, enzymatic and cellular assays 2012
- Synthesis of 3-Halo-2-(Hetero)Arylthienopyridines through a three-step methodology from 2,3-Dihalopyridines, Methanethiolate, (Hetero)Arylalkynes and Electrophiles 2012
- Synthesis of Di(Hetero)Arylamines and Ethers in the Thieno[3,2-b]Pyridine series by Metal-Catalyzed couplings 2012
- Synthesis of novel 1-Aryl-3-[2-,3- Or 4-(Thieno[3,2-b]Pyridin-7-Ylthio)Phenyl]Ureas and evaluation as VEGFR2 Tyrosine kinase inhibitors 2012
- Synthesis of novel 1-aryl-3-[2,3- or 4-(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas and evaluation as VEGFR2 tyrosine kinase inhibitors 2012
- Thieno[3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on human tumor cell lines 2012
- Fluorescence studies on new potential antitumoral 1,3-diarylurea derivatives of thieno[3,2-b]pyridines in solution and in nanoliposomes 2011
- Synthesis of 1,3-diaryl(thio)ureas in the thieno[3,2-b]pyridine series by palladium-catalyzed couplings and reactions with aryliso(thio)cyanates 2011
- Synthesis of di(hetero)arylethers in the thieno[3,2-b]pyridine seres by copper/N,N-dimethylglycine catalyzed C-O coupling 2011
- Synthesis of 1,3-diarylureas derivatives of (thieno[3,2-b]pyridine-7-ylthio)anilines 2011
- Synthesis of 1,3-diarylureas from different (thieno3,2-b]pyridin-7-ylthio)anilines 2011
- Synthesis of di(hetero)arylethers in the thieno[3,2-b]pyridine series by copper/N,N-dimethylglycine catalysed C-O coupling 2011
- Methyl 3-[4-(3-arylureido)phenylamino]thieno[3,2-b]pyridine-2-carboxylates as potential inhibitors of VEGFR-2: synthesis and molecular modelling studies 2011
- Methyl 3-amino-6-[4- or 3- or 2- (3-arylureido)phenyl]thieno[3,2-b]pyridine-2-carboxylates: synthesis and molecular modelling studies using VEGFR-2 2011
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teses