publicações selecionadas
-
artigo académico
- Integrating genetic and immune factors to uncover pathogenetic mechanisms of viral-associated pulmonary aspergillosis. Mbio. 2024
- Metabolic regulation of the host–fungus interaction: from biological principles to therapeutic opportunities. Journal of Leukocyte Biology. 2024
- A signature of differential gene expression in bronchoalveolar lavage fluid predicts mortality in influenza-associated pulmonary aspergillosis. Intensive Care Medicine. 2023
- Understanding the genetic basis of immune responses to fungal infection. Expert Review of Anti-Infective Therapy. 2022
- Targeting immunometabolism in host-directed therapies to fungal disease. Clinical and Experimental Immunology. 2022
- Early IL-10 promotes vasculature associated CD4+ T cells unable to control Mycobacterium tuberculosis infection. JCI Insight. 2021
- Paracoccin Overexpression in Paracoccidioides brasiliensis Enhances Fungal Virulence by Remodeling Chitin Properties of the Cell Wall. Journal of Infectious Diseases. 2021
- Microbiota-derived metabolites as diagnostic markers for respiratory fungal infections. Journal of Pharmaceutical and Biomedical Analysis. 2020
- Ectopic pregnancy – Six years experience in a secondary hospital. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2019
- Impact of nulliparous women's pre-pregnancy weight and risk of laceration at birth. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2019
- Host Genetic Signatures of Susceptibility to Fungal Disease. Current Topics in Microbiology and Immunology. 2019
- Host Genetics Takes a Toll on Immunity to Cryptococcus. EBioMedicine. 2018
- Toward the Identification of a Genetic Risk Signature for Pulmonary Aspergillosis in Chronic Obstructive Pulmonary Disease. Clinical Infectious Diseases. 2018
- Editorial: An omics perspective on fungal infection: Toward next-generation diagnosis and therapy. Antibiotics. 2017
- Host-Derived Biomarkers for Risk Assessment of Invasive Fungal Diseases. Methods in Molecular Biology. 2017
- IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity. Journal of Allergy and Clinical Immunology. 2017
- PTX3-Based Genetic Testing for Risk of Aspergillosis after Lung Transplant. Clinical Infectious Diseases. 2015
- IL-22 and IDO1 Affect Immunity and Tolerance to Murine and Human Vaginal Candidiasis. PLoS Pathogens. 2013
- Host genetics and invasive fungal diseases: Towards improved diagnosis and therapy?. Expert Review of Anti-Infective Therapy. 2012
- Inflammation in aspergillosis: The good, the bad, and the therapeutic. Annals of the New York Academy of Sciences. 2012
-
artigo de conferência
-
artigo de revista
- Echinacea purpurea Fractions Represent Promising Plant-Based Anti-Inflammatory Formulations. Antioxidants. 2023
- Erythrocyte-derived liposomes for the treatment of inflammatory diseases. Journal of Drug Targeting. 2022
- Erythrocyte-derived liposomes for the treatment of inflammatory diseases. Journal of Drug Targeting. 2022
- Functional Genetic Variants in ATG10 Are Associated with Acute Myeloid Leukemia. Cancers. 2021
- Biofunctionalized Liposomes to Monitor Rheumatoid Arthritis Regression Stimulated by Interleukin-23 Neutralization. Advanced Healthcare Materials. 2021
- Biofunctionalized Liposomes to Monitor Rheumatoid Arthritis Regression Stimulated by Interleukin-23 Neutralization. Advanced Healthcare Materials. 2021
- Polymorphisms within the TNFSF4 and MAPKAPK2 loci influence the risk of developing invasive aspergillosis: A two-stage case control study in the context of the aspBIOmics consortium. Journal of Fungi. 2021
- COVID-19-Associated Candidiasis (CAC): An Underestimated Complication in the Absence of Immunological Predispositions?. Journal of Fungi. 2020
- COVID-19 Associated Pulmonary Aspergillosis (CAPA): From Immunology to Treatment. Journal of Fungi. 2020
- Mothers' distress exposure and children's withdrawn behavior – A moderating role for the Interferon Gamma gene (IFNG). Developmental Psychobiology. 2020
- High-resolution melting assay for genotyping variants of the CYP2C19 enzyme and predicting voriconazole effectiveness. Antimicrobial Agents and Chemotherapy. 2019
- Biofunctional Nanofibrous Substrate for Local TNF-Capturing as a Strategy to Control Inflammation in Arthritic Joints. Nanomaterials. 2019
- Biofunctional Nanofibrous Substrate for Local TNF-Capturing as a Strategy to Control Inflammation in Arthritic Joints. Nanomaterials. 2019
- Ploidy Determination in the Pathogenic Fungus Sporothrix spp.. Antibiotics. 2019
- Amino acid metabolism as drug target in autoimmune diseases. Autoimmunity Reviews. 2019
- Genetic Regulation of the Host-Fungus Interaction in the Pathogenesis of Aspergillosis. Current Fungal Infection Reports. 2019
- Genetic defects in fungal recognition and susceptibility to invasive pulmonary aspergillosis. Blood. 2019
- Immune parameters for diagnosis and treatment monitoring in invasive mold infection. Journal of Fungi. 2019
- PTX3 Polymorphisms Influence Cytomegalovirus Reactivation After Stem-Cell Transplantation. Frontiers in Immunology. 2019
- The impact of IL-10 dynamic modulation on host immune response against visceral leishmaniasis. Cytokine. 2018
- The impact of IL-10 dynamic modulation on host immune response against visceral leishmaniasis. Cytokine. 2018
- L-Threonine Supplementation During Colitis Onset Delays Disease Recovery. Frontiers in Physiology. 2018
- Genetic deficiency of NOD2 confers resistance to invasive aspergillosis. Nature Communications. 2018
- Interleukin-6 Neutralization by Antibodies Immobilized at the Surface of Polymeric Nanoparticles as a Therapeutic Strategy for Arthritic Diseases. ACS Applied Materials and Interfaces. 2018
- Interleukin-6 Neutralization by Antibodies Immobilized at the Surface of Polymeric Nanoparticles as a Therapeutic Strategy for Arthritic Diseases. ACS Applied Materials and Interfaces. 2018
- Calcium sequestration by fungal melanin inhibits calcium-calmodulin signalling to prevent LC3-associated phagocytosis. Nature Microbiology. 2018
- Cytotoxic T lymphocyte antigen-4 gene polymorphisms and susceptibility to type 1 autoimmune hepatitis in the Tunisian population. Genes and Diseases. 2018
- Deficiency of immunoregulatory indoleamine 2,3-dioxygenase 1 in juvenile diabetes. JCI Insight. 2018
- Metabolic Regulation of Innate Immunity to Fungal Infection. EXS. 2018
- Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus. Nature. 2018
- Impact of Paracoccin Gene Silencing on Paracoccidioides brasiliensis Virulence. Mbio. 2017
- Impact of Paracoccin Gene Silencing on Paracoccidioides brasiliensis Virulence. Mbio. 2017
- Evaluation of bronchoalveolar lavage fluid cytokines as biomarkers for invasive pulmonary aspergillosis in at-risk patients. Antibiotics. 2017
- Fungal Vaccines and Immunotherapeutics: Current Concepts and Future Challenges. Current Fungal Infection Reports. 2017
- Fungal Vaccines and Immunotherapeutics: Current Concepts and Future Challenges. Current Fungal Infection Reports. 2017
- The Cell Biology of the Trichosporon-Host Interaction. Frontiers in Cellular and Infection Microbiology. 2017
- The Cell Biology of the Trichosporon-Host Interaction. Frontiers in Cellular and Infection Microbiology. 2017
- The absence of NOD1 enhances killing of Aspergillus fumigatus through modulation of dectin-1 expression. Frontiers in Immunology. 2017
- The microbiome-metabolome crosstalk in the pathogenesis of respiratory fungal diseases. Virulence. 2017
- The microbiome-metabolome crosstalk in the pathogenesis of respiratory fungal diseases. Virulence. 2017
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. Cell Metabolism. 2016
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. Cell Metabolism. 2016
- Immunometabolic Pathways in BCG-Induced Trained Immunity. Cell Reports. 2016
- Genetic Variation in Autophagy-Related Genes Influences the Risk and Phenotype of Buruli Ulcer. PLoS Neglected Tropical Diseases. 2016
- Polymorphisms in Host Immunity-Modulating Genes and Risk of Invasive Aspergillosis: Results from the AspBIOmics Consortium.. Infection and Immunity. 2016
- Common genetic polymorphisms within NF¿B-related genes and the risk of developing invasive aspergillosis. Antibiotics. 2016
- The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells. Journal of Experimental Medicine. 2016
- Paving the way for predictive diagnostics and personalized treatment of invasive aspergillosis. Antibiotics. 2015
- Genetic PTX3 Deficiency and Aspergillosis in Stem-Cell Transplantation. New England Journal of Medicine. 2014
- Neutrophil Responses to Aspergillosis: New Roles for Old Players. Mycopathologia. 2014
- TLR9 Activation Dampens the Early Inflammatory Response to Paracoccidioides brasiliensis, Impacting Host Survival. PLoS Neglected Tropical Diseases. 2013
- Th17/Treg Imbalance in Murine Cystic Fibrosis Is Linked to Indoleamine 2,3-Dioxygenase Deficiency but Corrected by Kynurenines. American Journal of Respiratory and Critical Care Medicine. 2013
- Th17/Treg Imbalance in Murine Cystic Fibrosis Is Linked to Indoleamine 2,3-Dioxygenase Deficiency but Corrected by Kynurenines. American Journal of Respiratory and Critical Care Medicine. 2013
- CD4(+) T cell vaccination overcomes defective cross-presentation of fungal antigens in a mouse model of chronic granulomatous disease. Journal of Clinical Investigation. 2012
- DAMP signaling in fungal infections and diseases. Frontiers in Immunology. 2012
- Dectin-1 isoforms contribute to distinct Th1/Th17 cell activation in mucosal candidiasis. Cellular & Molecular Immunology. 2012
- Dectin-1 isoforms contribute to distinct Th1/Th17 cell activation in mucosal candidiasis. Cellular & Molecular Immunology. 2012
- From memory to antifungal vaccine design. Trends in Immunology. 2012
- Host defense pathways against fungi: The basis for vaccines and immunotherapy. Antibiotics. 2012
- Immunity and tolerance to fungi in hematopoietic transplantation: Principles and perspectives. Frontiers in Immunology. 2012
- Immunity and tolerance to fungi in hematopoietic transplantation: Principles and perspectives. Frontiers in Immunology. 2012
- Immunotherapy of aspergillosis. Clinical Microbiology and Infection. 2012
- TLR3 essentially promotes protective class I-restricted memory CD8 T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients. Blood. 2012
- TLR3 essentially promotes protective class I-restricted memory CD8 T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients. Blood. 2012
- The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma. Genes and Immunity. 2012
- The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma. Genes and Immunity. 2012
- The C Allele of rs5743836 Polymorphism in the Human TLR9 Promoter Links IL-6 and TLR9 Up-Regulation and Confers Increased B-Cell Proliferation. Antibiotics. 2011
- The C Allele of rs5743836 Polymorphism in the Human TLR9 Promoter Links IL-6 and TLR9 Up-Regulation and Confers Increased B-Cell Proliferation. Antibiotics. 2011
- Genetic susceptibility to aspergillosis in allogeneic stem-cell transplantation. Blood. 2011
- Genetically-Determined Hyperfunction of the S100B/RAGE Axis Is a Risk Factor for Aspergillosis in Stem Cell Transplant Recipients. Antibiotics. 2011
- Immunity and tolerance to infections in experimental hematopoietic transplantation. Best Practice & Research Clinical Haematology. 2011
- Immunogenetic Profiling to Predict Risk of Invasive Fungal Diseases: Where Are We Now?. Immunological Investigations. 2011
- Immunogenetic Profiling to Predict Risk of Invasive Fungal Diseases: Where Are We Now?. Immunological Investigations. 2011
- Cracking the Toll-like receptor code in fungal infections. Expert Review of Anti-Infective Therapy. 2010
- Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of antifungal immunity. Blood. 2010
- Non-hematopoietic cells contribute to protective tolerance to Aspergillus fumigatus via a TRIF pathway converging on IDO. Cellular & Molecular Immunology. 2010
- Cdc42p controls yeast-cell shape and virulence of Paracoccidioides brasiliensis. Fungal Genetics and Biology. 2009
- Polymorphisms in Toll-like receptor genes and susceptibility to infections in allogeneic stem cell transplantation. Experimental Hematology. 2009
- Polymorphisms in Toll-like receptor genes and susceptibility to infections in allogeneic stem cell transplantation. Experimental Hematology. 2009
- T-1237C polymorphism of TLR9 gene is not associated with multiple sclerosis in the Portuguese population. Multiple Sclerosis. 2008
- Nitric Oxide Signaling Is Disrupted in the Yeast Model for Batten Disease. Endocrinology. 2007
- Nitric Oxide Signaling Is Disrupted in the Yeast Model for Batten Disease. Endocrinology. 2007
- Multiplex PCR identification of eight clinically relevant Candida species. Blood. 2007
- Responses of antioxidant defenses to Cu and Zn stress in two aquatic fungi. Heredity. 2007
- Study of disease-relevant polymorphisms in the TLR4 and TLR9 genes: A novel method applied to the analysis of the Portuguese population. Molecular and Cellular Probes. 2007
- Towards a molecular genetic system for the pathogenic fungus Paracoccidioides brasiliensis. Fungal Genetics and Biology. 2007
-
capítulo de livro
-
documento
- The key role of alveolar macrophages in shaping the CD4+ T cell activation and control os M. tuberculosis infection 2024
- Sialidase-1 as a key virulence factor in Sporothrix brasiliensis infection 2023
- Spatiotemporal profiling of gene expression during sarcoid granuloma formation 2023
- Erythrocyte-derived liposomes asanti-inflammatory carriers 2022
- Regulation of antifungal immunity and inflammation by HIF-1a in chronic obstructive pulmonary disease 2021
- The role of PTX3 in innate regulation of antifungal immunity in Chronic Pulmonary Aspergillosis 2020
- PTX3-dependent regulation of antifungal immunity in Chronic Pulmonary Aspergillosis 2019
- Glutamine metabolism regulates the immune response to the fungal pathogen Aspergillus fumigatus 2019
- Paracoccin overexpression in Paracoccidioides brasiliensis reveals the influence of chitin hydrolysis on fungal virulence and host immune response 2019
- Capture and neutralization of interleukin-6 by the intra-articular injection of biofunctionalized polymeric nanoparticles as advanced treatment for arthritic diseases 2018
- Ploidy and genetic transformation of Sporothrix brasiliensis 2018
- Dietary zinc supplementation promotes tumor overgrowth through a microbiota-tumor axis 2017
- Sporothrix brasiliensis: ploidy and genetic transformation 2017
- Biofunctionalized polymeric nanoparticles for a prolonged and local capture of pro-inflammatory cytokines in arthritic joints 2016
-
livro
-
teses