publicações selecionadas
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artigo académico
- Golgi a-mannosidase: opposing structures of Drosophila melanogaster and novel human model using molecular dynamics simulations and docking at different pHs. Journal of Biomolecular Structure & Dynamics. 2023
- Correction: Silva et al. Chemical Profile and Bioactivities of Extracts from Edible Plants Readily Available in Portugal. Foods 2021, 10, 673. Antibiotics. 2022
- Exploiting the Antiparasitic Activity of Naphthalimide Derivatives. International Journal of Chemistry and Pharmaceutical Sciences. 2016
- Novel pyridine-2,4,6-tricarbohydrazide derivatives: Design, synthesis, characterization and in vitro biological evaluation as a- and ß-glucosidase inhibitors. Bioorganic Chemistry. 2014
- STUDY BASED ON ELECTRONIC DESCRIPTORS OF THE DIASTEREOSELECTIVE AZA-DIELS-ALDER CYCLOADDITION OF [(1R)-10-(N,N-DIETHYLSULFAMOYL)ISOBORNYL] 2H-AZIRINE-3-CARBOXYLATE TO E,E-1,4-DIACETOXY-1,3-BUTADIENE. Journal of the Chilean Chemical SocIETy. 2013
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artigo de conferência
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artigo de revista
- Concise synthesis of (S)-7-Hydroxy-5-aza-8a- epi - D -swainsonine from a d -erythrose derivative. Synthesis. 2022
- Chitosan Nano/Microformulations for Antimicrobial Protection of Leather with a Potential Impact in Tanning Industry. Materials. 2022
- Synthesis of novel sugar derived aziridines, as starting materials giving access to sugar amino acid derivatives. Amino Acids. 2021
- Chemical Profile and Bioactivities of Extracts from Edible Plants Readily Available in Portugal. Antibiotics. 2021
- Synthesis and Bioactivity of New Analogue of Bicyclic 1-Azafagomine. Chemistryselect. 2019
- A Short Synthesis of (2S,3S,4R)-Dihydroxyhomoprolines from d-Erythrose-Derived 5,6-Dihydro-2H-pyran-2-one. Synthesis. 2019
- (3S,4R)-3,4-Dihydroxy-N-alkyl-l-homoprolines: synthesis and computational mechanistic studies. Organic and Biomolecular Chemistry. 2019
- Synthesis of New Iminosugar Derivatives Based on (S)-(1,2,3,6-Tetrahydropyridazin-3-yl)methanol. Russian Journal of Organic Chemistry. 2019
- Total Stereoselective Michael Addition of N- and S- Nucleophiles to a d-Erythrosyl 1,5-Lactone Derivative. Experimental and Theoretical Studies Devoted to the Synthesis of 2,6-Dideoxy-4-functionalized-d-ribono-hexono-1,4-lactone. Journal of Organic Chemistry. 2018
- Molecular docking and glucosidase inhibition studies of novel N-arylthiazole-2-amines and Ethyl 2-[aryl(thiazol-2-yl)amino]acetates. Medicinal Chemistry Research. 2017
- Total Facial Discrimination of 1,3-Dipolar Cycloadditions in a d-Erythrose 1,3-Dioxane Template: Computational Studies of a Concerted Mechanism. Journal of Organic Chemistry. 2017
- Styrene Epoxidation Over Heterogeneous Manganese(III) Complexes. Archives of Metallurgy and Materials. 2016
- Exploiting the antiparasitic activity of naphthalimides derivatives. International Journal of Chemistry and Pharmaceutical Sciences. 2016
- Total Facial Selectivity of a D-Erythrosyl Aromatic Imine in [4p+2p] Cycloadditions; Synthesis of 2-Alkylpolyol 1,2,3,4-Tetrahydroquinolines. Organic and Biomolecular Chemistry. 2016
- Evaluation of New Naphthalimides as Potential Anticancer Agents against Breast Cancer MCF-7, Pancreatic Cancer BxPC-3 and Colon Cancer HCT- 15 Cell Lines. Organic Chemistry: Current Research. 2015
- Norbornene Oxidation by Chiral Complexes Encapsulated in NaY Zeolite. Journal of Physical Chemistry C. 2014
- Enantioselective Diels-Alder Cycloadditions in the Synthesis of Two Enantiomeric Sets of Chiral Polihydroxylated Pipecolic Acid Derivatives. Synlett. 2014
- Study based on electronic descriptors of the diastereoselective aza-diels-alder cycloaddition of [(1r)-10-(n,n-diethylsulfamoyl)isobornyl] 2h-azirine-3-carboxylate to e,e-1,4-diacetoxy-1,3-butadiene. Journal of the Chilean Chemical SocIETy. 2013
- Diastereoselectivity in diels-alder cycloadditions of erythrose benzylidene-acetal 1,3-butadienes with maleimides. Synlett. 2012
- Diels-alder cycloaddition in the synthesis of 1-azafagomine, analogs, and derivatives as glycosidase inhibitors. Mini-Reviews in Medicinal Chemistry. 2012
- Advances in the synthesis of homochiral (-)-1-azafagomine and (+)-5-epi-1-azafagomine. 1-N-phenyl carboxamide derivatives of both enantiomers of 1-azafagomine: Leads for the synthesis of active a-glycosidase inhibitors.. Journal of Organic Chemistry. 2011
- Highly diastereoselective synthesis of 2-azabicyclo[2.2.1]hept-5-ene derivatives: Bronsted acid catalyzed aza-Diels-Alder reaction between cyclopentadiene and imino-acetates with two chiral auxiliaries. Tetrahedron. 2011
- Ethyl 3-(2-pyridyl)-2H-azirine-2-carboxylate: Synthesis and reaction with dienes. Synthesis. 2005
- Synthesis of 1,3,8,8a-tetrahydro-3,8-epoxyazirino[1,2-b]isoquinolines and their reactions with oxygen nucleophiles. Heterocycles. 2005
- Diels-Alder cycloaddition of 2-azadienes to methyl 2-(2,6-dichlorophenyl)- 2H-azirine-3-carboxylate in the synthesis of methyl 4-oxo-1,3-diazabicyclo[4.1. 0]heptane-6-carboxylates. Tetrahedron. 2004
- Cycloaddition of methyl 2-(2,6-dichorophenyl)-2H-azirine-3-carboxylate to electron-rich 2-azadienes. Tetrahedron Letters. 2003
- Stereoselective cycloaddition of 1-glucosyl-1,3-butadienes with tert-butyl 2H-azirine-3-carboxylate, glyoxylates and imines. Tetrahedron Letters. 2003
- Intermolecular alkyl radical addition to methyl 2-(2,6-dichlorophenyl)-2H-azirine-3-carboxylate. Synlett. 2003
- Optically active aziridine esters by nucleophilic addition of nitrogen heterocycles to a chiral 2H-azirine-2-carboxylic ester. Tetrahedron Letters. 2003
- Diels–alder reactions of alkyl 2H-azirine-3-carboxylates with furans. Journal of the Chemical SocIETy-Perkin Transactions 1. 2001
- Novel aziridine esters by the addition of aromatic nitrogen heterocycles to a 2H-azirine-3-carboxylic ester. Tetrahedron Letters. 2000
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capítulo de livro
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documento
- Stereoselective synthesis of 5-substituted hexahydropyrroquinolines-2,3-diol from functionalized tetrahydroquinolines 2019
- Development of nanoparticles for antimicrobial protection of leather coatings 2016
- Diastereoselective synthesis of analogues of neuraminic acid 2015
- Synthesis and biological evaluation of mono and bis naphthalimides derivatives against SH-5Y-SY, human brain cancer cells 2015
- Total facial selectivity in 2π+4π reactions of (2R,4S,5R)-4-((E)-((4-Methoxyphenyl)imino)methyl)-2-phenyl-1,3-dioxan-5-ol to electron-rich dienophiles 2015
- Enantiospecific 1,3-Dipolar Cycloadditions between Azadienophiles and 2-Phenyl-4,4a-dihydropyrano[3,2-d][1,3]dioxin-6(8aH)-one 2013
- Synthesis of (2'r,4a'r,8a's)-8'-(Benzylamino)-2'-Phenyldihydro-4'h-Spiro[Diazirinyl-1,7'-Pyrano[3,2-D][1,3]Dioxin]-6'(4a'h)-One 2013
- 1,3-dipolar cycloaddition of (2R,4aR,8aS)-2-phenyl-4,4a-dihydropyrano[3,2-d][1,3]dioxin-6(8aH)-one with aromatic diazomethyl compounds 2012
- Asymmetric diels-alder reaction of tert-butyl 2H-azirine-3-carboxylate by a self-assembled complex of binol, mg and zn 2012
- Synthesis of 2-n-benzyl carboxamide derivates of 1-azafagomine 2012
- Diastereo-selectivity of diels-alder cycloaddtions of erythrose benzylidene-acetal 1,3-Butadienes with maleimides 2012
- Highly diastereoselective synthesis of aza-diels-alder reaction of danishefsky diene wiht glyoxylate imines 2012
- A concise synthesis of 8a-epi-swaisonine analogue 2011
- Chemoenzymatic synthesis of 1-azafagomine analogues 2011
- Enantioselective Diels-Alder methodology in the synthesis of azasugars 2011
- Synthesis of 1-azafagomine analog and 1-N-phenyl carboxamide 1-azafagomine containing erythrose units 2011
- Synthesis of 5-substituted piperazinic acid precursors 2011
- The synthesis of an homochiral aziridine as a useful synton to iminosugars and amino acid compounds 2011
- Enantioselective diels-alder methodology in the synthesis of (-)-1-azafagomine 2010
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poster de conferência