publicações selecionadas
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artigo académico
- Salivary IL-1ß, IL-6, and IL-10 Are Key Biomarkers of Periodontitis Severity. International Journal of Molecular Sciences. 2024
- Akkermansia muciniphila and Parabacteroides distasonis as prognostic markers for relapse in ulcerative colitis patients. Frontiers in Cellular and Infection Microbiology. 2024
- Deregulated immune cell recruitment orchestrated by c-MET impairs pulmonary inflammation and fibrosis. Respiratory Research. 2024
- Akkermansia muciniphila and Parabacteroides distasonis synergistically protect from colitis by promoting ILC3 in the gut. Mbio. 2024
- Cisplatin-Resistant Urothelial Bladder Cancer Cells Undergo Metabolic Reprogramming beyond the Warburg Effect. Cancers. 2024
- Enhancing Immunotherapy in Ovarian Cancer: The Emerging Role of Metformin and Statins. International Journal of Molecular Sciences. 2023
- Intramacrophage lipid accumulation compromises T cell responses and is associated with impaired drug therapy against visceral leishmaniasis. Immunology. 2023
- Repetitive mRNA vaccination is required to improve the quality of broad-spectrum anti-SARS-CoV-2 antibodies in the absence of CXCL13.. Science Advances. 2023
- Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation.. Journal of Lipid Research. 2023
- Toll-like receptor 2 selectively modulates Ras isoforms expression in Leishmania major infection.. Cytokine. 2023
- Leishmania donovani Induces Multiple Dynamic Responses in the Metabolome Associated with Amastigote Differentiation and Maturation Inside the Human Macrophage. Journal of Proteome Research. 2023
- Development of a Versatile Toolbox for Genetic Manipulation of Sporothrix brasiliensis. Microbiology Spectrum. 2023
- Post-acute sequelae of COVID-19 is characterized by diminished peripheral CD8+ß7 integrin+ T cells and anti-SARS-CoV-2 IgA response. Nature Communications. 2023
- Glutamine Metabolism Supports the Functional Activity of Immune Cells against Aspergillus fumigatus. Microbiology Spectrum. 2023
- PTX3 Inhibits Complement-Driven Macrophage Activation to Restrain Granuloma Formation in Sarcoidosis.. American Journal of Respiratory and Critical Care Medicine. 2022
- Galectin-3 binding protein stimulated IL-6 expression is impeded by antibody intervention in SARS-CoV-2 susceptible cell lines. Acta Cytologica. 2022
- Hypoxia inducible-factor 1 alpha regulates neutrophil recruitment during fungal-elicited granulomatous inflammation. Frontiers in Cellular and Infection Microbiology. 2022
- Low quantity and quality of anti-spike humoral response is linked to CD4 T-cell apoptosis in COVID-19 patients. Cell Death and Differentiation. 2022
- IL-10 Overexpression After BCG Vaccination Does Not Impair Control of Mycobacterium tuberculosis Infection.. Frontiers in Immunology. 2022
- The Role of Biobanks in the Fight against COVID-19 Pandemic: The Portuguese Response. Acta Médica Portuguesa. 2022
- Macrophage-targeted shikonin-loaded nanogels for modulation of inflammasome activation.. Nanomedicine : nanotechnology, biology, and medicine. 2022
- T cell apoptosis characterizes severe Covid-19 disease. Cell Death and Differentiation. 2022
- Dysregulation of glycerophospholipid metabolism during Behçet's disease contributes to a pro-inflammatory phenotype of circulating monocytes. Emerging Microbes & Infections. 2021
- Early IL-10 promotes vasculature associated CD4+ T cells unable to control Mycobacterium tuberculosis infection. JCI Insight. 2021
- Immune-metabolic interactions between Leishmania and macrophage host. Current Opinion in Microbiology. 2021
- Nutritional adjuvants with antioxidant properties in the treatment of canine leishmaniasis.. Veterinary Parasitology. 2021
- Enhanced Glycolysis Is Required for Antileishmanial Functions of Neutrophils Upon Infection With Leishmania donovani. Frontiers in Immunology. 2021
- Interleukin-6 Is a Biomarker for the Development of Fatal Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia. Frontiers in Immunology. 2021
- Interdependencies between Toll-like receptors in Leishmania infection. Immunology. 2021
- Spatial distribution of canine Leishmania infantum infection in a municipality with endemic human leishmaniasis in Eastern Bahia, Brazil. Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria. 2021
- Mimicking Behcet's disease: GM-CSF gain of function mutation in a family suffering from a Behcet's disease-like disorder marked by extreme pathergy.. Clinical and Experimental Immunology. 2020
- Non-human primates and Leishmania immunity. Cytokine: X. 2020
- Cytokines and metabolic regulation: A framework of bidirectional influences affecting Leishmania infection. Cytokine. 2020
- Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity. Nature Communications. 2020
- Development and Characterization of an Avirulent Leishmania major Strain. The Journal of Immunology. 2020
- IL-17A and IL-17F orchestrate macrophages to promote lung cancer. Cellular Oncology. 2020
- Glutamine supplementation improves the efficacy of miltefosine treatment for visceral leishmaniasis. PLoS Neglected Tropical Diseases. 2020
- The Absence of HIF-1a Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis. Cell Reports. 2020
- Cytokines in the immunity and immunopathogenesis in leishmaniases. Cytokine. 2020
- Feeding immunity: how amino acid metabolism modulates immune cell function. Immunometabolism. 2020
- IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity. Journal of Allergy and Clinical Immunology. 2017
- The influence of surface modified poly(L-lactic acid) films on the differentiation of human monocytes into macrophages. Biomaterials Science. 2017
- AMP-activated protein kinase as a target for pathogens: Friends or foes?. Current Drug Targets. 2016
- Correction: Early Loss of Splenic Tfh Cells in SIV-Infected Rhesus Macaques. 2016
- Response to the comment on "promising blood-derived biomarkers for estimation of the postmortem interval". Toxicology Research. 2016
- A breakthrough on Amanita phalloides poisoning: an effective antidotal effect by polymyxin B. 2015
- Leishmania infantum Modulates Host Macrophage Mitochondrial Metabolism by Hijacking the SIRT1-AMPK Axis. PLoS Pathogens. 2015
- Interleukin-1ß genotype and circulating levels in cancer patients: Metastatic status and pain perception. Clinical Biochemistry. 2014
- Impairment of T Cell Function in Parasitic Infections. PLoS Neglected Tropical Diseases. 2014
- Abortive T Follicular Helper Development Is Associated with a Defective Humoral Response in Leishmania infantum-Infected Macaques. PLoS Pathogens. 2014
- Crucial CD8+ T-lymphocyte cytotoxic role in amphotericin B nanospheres efficacy against experimental visceral leishmaniasis. Current Medicinal Chemistry. 2014
- The impact of distinct culture media in Leishmania infantum biology and infectivity. Parasitology. 2014
- Apoptose et Sida, une affaire d’intégration ?. M S-Medecine Sciences. 2013
- Correction: Profiling of RNA degradation for estimation of post mortem interval (PLoS ONE) 8, 2 (e56507) DOI: 10.1371/journal.pone.0056507. Antibiotics. 2013
- DRAM Triggers Lysosomal Membrane Permeabilization and Cell Death in CD4+ T Cells Infected with HIV. PLoS Pathogens. 2013
- Development of a Fluorescent Based Immunosensor for the Serodiagnosis of Canine Leishmaniasis Combining Immunomagnetic Separation and Flow Cytometry. PLoS Neglected Tropical Diseases. 2013
- Development of a simple and rapid spectrophotometric method for the quantification of carboxyhemoglobin. Toxicology Letters. 2013
- Exoproteome dynamics in Leishmania infantum. E-Polymers. 2013
- Leishmania-infected MHC class IIhigh dendritic cells polarize CD4+ T cells toward a nonprotective T-bet+ IFN-¿+ IL-10+ phenotype. Journal of Immunology. 2013
- Prevalence of antibodies to Leishmania infantum and Toxoplasma gondii in horses from the north of Portugal. Parasites & Vectors. 2013
- Profiling of RNA Degradation for Estimation of Post Morterm Interval. Antibiotics. 2013
- Impact of Continuous Axenic Cultivation in Leishmania infantum Virulence. PLoS Neglected Tropical Diseases. 2012
- Characterization and evaluation of BNIPDaoct-loaded PLGA nanoparticles for visceral leishmaniasis: In vitro and in vivo studies. Analytical Chemistry. 2012
- Characterization of Leishmania infantum thiol-dependent reductase 1 and evaluation of its potential to induce immune protection. Parasite Immunology. 2012
- Human periprostatic white adipose tissue is rich in stromal progenitor cells and a potential source of prostate tumor stroma. Experimental Biology and Medicine. 2012
- IL-2 immunotherapy in chronically SIV-infected Rhesus Macaques. Virology Journal. 2012
- Modulation of mammalian apoptotic pathways by intracellular protozoan parasites. Cellular Microbiology. 2012
- Seroepidemiological survey of Leishmania infantum infection in dogs from northeastern Portugal. Acta Tropica. 2011
- The Leishmania nicotinamidase is essential for NAD + production and parasite proliferation. Molecular Microbiology. 2011
- Activation of phosphatidylinositol 3-kinase/akt and impairment of nuclear factor-kB: Molecular mechanisms behind the arrested maturation/activation state of leishmania infantum-infected dendritic cells. American Journal of Pathology. 2010
- Application of an improved enzyme-linked immunosorbent assay method for serological diagnosis of canine leishmaniasis. Journal of Clinical Microbiology. 2010
- The contribution of Toll-like receptor 2 to the innate recognition of a Leishmania infantum silent information regulator 2 protein. Immunology. 2009
- Differential roles of PI3-Kinase, MAPKs and NF-¿B on the manipulation of dendritic cell Th1/Th2 cytokine/chemokine polarizing profile. Molecular Immunology. 2009
- Evaluation of Leishmania species reactivity in human serologic diagnosis of leishmaniasis. American Journal of Tropical Medicine and Hygiene. 2009
- Recognition of Leishmania parasites by innate immunity. Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 2009
- Serological evaluation of experimentally infected dogs by LicTXNPx-ELISA and amastigote-flow cytometry. Veterinary Parasitology. 2008
- Live attenuated Leishmania vaccines: a potential strategic alternative. Archivum Immunologiae et Therapiae Experimentalis. 2008
- A Leishmania infantum cytosolic tryparedoxin activates B cells to secrete interleukin-10 and specific immunoglobulin. Immunology. 2008
- High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas. Annals of Surgical Oncology. 2008
- Immune response regulation by Leishmania secreted and nonsecreted antigens. Biomed Research International. 2007
- SIR2-deficient Leishmania infantum induces a defined IFN-¿/IL-10 pattern that correlates with protection. Journal of Immunology. 2007
- Leishmania cytosolic silent information regulatory protein 2 deacetylase induces murine B-cell differentiation and in vivo production of specific antibodies. Immunology. 2006
- In vitro antileishmanial activity of nicotinamide. Antimicrobial Agents and Chemotherapy. 2005
- Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites. Cell. 2005
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artigo de conferência
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artigo de revista
- Analysis of Salivary Levels of IL-1ß, IL17A, OPG and RANK-L in Periodontitis Using the 2017 Classification of Periodontal Diseases-An Exploratory Observational Study.. Journal of Clinical Medicine. 2023
- Immune Tumor Microenvironment in Ovarian Cancer Ascites. International Journal of Molecular Sciences. 2022
- Leishmania infantum Infection of Primary Human Myeloid Cells. Antibiotics. 2022
- Mathematical Modelling Using Predictive Biomarkers for the Outcome of Canine Leishmaniasis upon Chemotherapy. Antibiotics. 2020
- Definition of the Anti-inflammatory Oligosaccharides Derived From the Galactosaminogalactan (GAG) From Aspergillus fumigatus. Frontiers in Cellular and Infection Microbiology. 2019
- Methods for the analysis of transcriptome dynamics. Toxicology Research. 2019
- PTX3 Polymorphisms Influence Cytomegalovirus Reactivation After Stem-Cell Transplantation. Frontiers in Immunology. 2019
- The impact of IL-10 dynamic modulation on host immune response against visceral leishmaniasis. Cytokine. 2018
- More than just exosomes: distinct Leishmania infantum extracellular products potentiate the establishment of infection.. Journal of Extracellular Vesicles. 2018
- L-Threonine Supplementation During Colitis Onset Delays Disease Recovery. Frontiers in Physiology. 2018
- The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques. Journal of Clinical Investigation. 2018
- Alterations on Cellular Redox States upon Infection and Implications for Host Cell Homeostasis.. EXS. 2018
- Metabolic Crosstalk Between Host and Parasitic Pathogens.. EXS. 2018
- Infection of hematopoietic stem cells by Leishmania infantum increases erythropoiesis and alters the phenotypic and functional profiles of progeny.. Cellular Immunology. 2017
- The influence of surface modified poly(L-lactic acid) films on the differentiation of human monocytes into macrophages. Biomaterials Science. 2017
- CD4 T follicular helper cells and HIV infection: Friends or enemies?. Frontiers in Immunology. 2017
- Evaluation of bronchoalveolar lavage fluid cytokines as biomarkers for invasive pulmonary aspergillosis in at-risk patients. Antibiotics. 2017
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. Cell Metabolism. 2016
- Immunometabolic Pathways in BCG-Induced Trained Immunity. Cell Reports. 2016
- Exploring NAD(+) metabolism in host-pathogen interactions.. Cellular and Molecular Life Sciences. 2016
- AMP-activated Protein Kinase As a Target For Pathogens: Friends Or Foes?. Current Drug Targets. 2016
- AMPK in Pathogens. EXS. 2016
- Interleukin-27 early impacts Leishmania infantum infection in mice and correlates with active visceral disease in humans. Frontiers in Immunology. 2016
- Regulation of immunity during visceral Leishmania infection. Parasites & Vectors. 2016
- Vasculogenesis and Diabetic Erectile Dysfunction: How Relevant Is Glycemic Control?. Journal of Cellular Biochemistry. 2016
- Early Loss of Splenic Tfh Cells in SIV-Infected Rhesus Macaques.. PLoS Pathogens. 2015
- NF-¿B pathway controls mitochondrial dynamics.. Cell Death and Differentiation. 2015
- A breakthrough on Amanita phalloides poisoning: an effective antidotal effect by polymyxin B. Archives of Toxicology. 2015
- Myeloid Sirtuin 2 Expression Does Not Impact Long-Term Mycobacterium tuberculosis Control.. Antibiotics. 2015
- Promising blood-derived biomarkers for estimation of the postmortem interval. Toxicology Research. 2015
- The Warburg effect in mycobacterial granulomas is dependent on the recruitment and activation of macrophages by gamma interferon.. Immunology. 2015
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capítulo de livro
- Evaluating the Role of Host AMPK in Leishmania Burden.. Methods in Molecular Biology. 2018
- O Sistema Imunológico como alvo da toxicidade dos xenobióticos 2018
- AMPK in Pathogens 2016
- Imunologia da Infecção 2012
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documento
- Itaconate controls the metabolic activation of immune cells during granuloma formation 2024
- Deciphering the Role of Lipid Accumulation in Macrophages during Leishmania Infection 2024
- The key role of alveolar macrophages in shaping the CD4+ T cell activation and control os M. tuberculosis infection 2024
- Sialidase-1 as a key virulence factor in Sporothrix brasiliensis infection 2023
- Unraveling the dynamic effect of branched-chain amino acids in the gut: the influence of sex 2023
- Entrevista à Radio France Internationale acerca de "Post-acute Sequelae of COVID-19 is Characterized by diminished peripheral CD8+ß7+ T cells and Anti-SARS-CoV-2 IgA response" 2023
- Itaconate controls granulomatous inflammation in sarcoidosis 2023
- Análise proteómica de ascites de pacientes com cancro do ovário reflete a modificação metabólica no microambiente tumoral durante a quimioterapia 2023
- The influence of tumor microenvironment immunein ovarian cancer ascites 2023
- Characterization of Leishmania donovani infection in the gut: from the epithelial barrier to the immune system 2022
- Profiling of rat mRNA transcripts degradation for the postmortem interval estimation 2022
- Unraveling the dinamic effect of Branched Chain Amino Acids in the gut 2022
- Immune tumor microenvironment of ovarian cancer ascites 2022
- The influence of tumor microenvironment immunein ovarian cancer ascites 2022
- Regulation of antifungal immunity and inflammation by HIF-1a in chronic obstructive pulmonary disease 2021
- Unraveling the dinamic effect of Branched Chain Amino Acids in the gut 2021
- Molécula que pode prever a evolução dos doentes de Covid-19 2021
- Molécula IL-6 dá indicação da evolução dos doentes Covid 2021
- A molécula que pode ajudar o SNS: IL-6 pode prever a evolução dos doentes com COVID-19 2021
- Medir regularmente a quantidade da molécula IL-6 ajuda a antecipar e combater a Covid-19 2021
- Glutamine metabolism regulates the immune response to the fungal pathogen Aspergillus fumigatus 2019
- L- Threonine supplementation during colitis onset delays disease 2018
- Deciphering the microbiome and metabolic factors contributing to protection against ulcerative colitis. 2018
- Genetically-determined NLRP3 hyperactivation confers risk to fungal disease by compromising macrophage function 2018
- Pentraxin-3 promotes IL-10-dependent immune protection to the oppurtunistic fungus Trichosporon asahii 2018
- Elucidating the impact of IL-17A/F in lung cancer 2018
- Evaluation of alveolar cytokines as biomarkers for invasive pulmonary aspergillosis in high-risk patients 2018
- IL-10 overexpression in vivo promotes susceptibility to aspergillosis by supressing innate and adaptive pulmonary antifungal immunity 2018
- Dietary zinc supplementation promotes tumor overgrowth through a microbiota-tumor axis 2017
- Influence of surface modified poly(L-lactic acid) films on the differentiation of human monocytes into macrophages 2017
- Immunometabolic characterization of the intestinal mucosa upon chemically-induced colitis in mice from different animal facilities 2016
- Response to the comment on “Promising blood-derived biomarkers for estimation of the postmortem interval’’. Toxicology Research. 2016
- IL-10 mediates susceptibility to Listeria monocytogenes infection by modulating the accumulation and differentiation of CD11b+ Ly6C+ monocytes 2014
- Parasita da leishmaniose torna-nos cúmplices da sua infecção 2013
- Trajectórias Desenvolvimentais dos Problemas Emocionais e Comportamentais na Infância e Adolescência 2013
- Factores Individuais e Familiares Relacionados com os Problemas de Comportamento em Jovens 2012
- Poster 14 The development of a semi-defined medium for growth of Leishmania infantum 2012
- Leishmania-infected mature dendritic cells polarize CD4+ T cells towards a non-protective T-bet+ INF-gamma+ IL10+ phenotype 2012
- Activation of IL-27 p28 gene transcription on antigen presenting cells infected with Leishmania infantum 2011
- Infected but not Bystander Dendritic Cells polarize CD4+ T cells towards a non-protective T-bet+ INF-gamma+ IL10+ phenotype 2011
- Poster 23 Early stages of visceral Leishmania infection 2011
- Differential effect of Leishmania infantum on infected and bystander dendritic cells 2010
- Immunomodulation of dendritic cells by virulent and attenuated Leishmania infantum strains 2009
- Poster 526 Evaluation of Leishmania species reactivity in the Human serological diagnostic of leishmaniasis 2009
- Poster 530 Serological evaluation of experimentally infected dogs by LicTXNPx–ELISA and amastigote-flow cytometry 2009
- Poster PA11/60 Immunomodulation of dendritic cells by virulent and attenuated Leishmania infantum strains 2009
- Antibodies against rLmS3arp enhance the Leishmania uptake by murine peitoneal macrophages 2003
- Cholesteryl hemiazelate Identified in Cardiovascular Disease Patients Causesin vitroandin vivoInflammation
- Galectin-3 binding protein stimulated IL-6 expression is impeded by antibody intervention in SARS-CoV-2 susceptible cell lines
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livro
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teses