publicações selecionadas
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artigo académico
- Peri-Carotid Adipose Tissue and Atherosclerosis at Carotid Bifurcation. Journal of Cardiovascular Development and Disease. 2024
- SNX27: A Trans-Species Cognitive Modulator with implications for Anxiety and Stress Susceptibility. Neurobiology of Stress. 2024
- IODINEMINHO STUDY: IODINE SUPPLEMENTATION AND PREVALENCE OF IODINE DEFICIENCY IN PREGNANT WOMEN. J Clinical Endocrinology and Metabolism. 2024
- Chronic Mycobacterium avium infection differentially affects the cytokine expression profile of three mouse strains, but has no effect on behavior. Acta Cytologica. 2023
- COVID-19 pandemic and the quality of antibiotic use in primary care: an interrupted time-series study. International Journal for Quality in Health Care. 2023
- Impact of inflammation on chronic limb-threatening ischaemia. Angiologia e Cirurgia Vascular. 2023
- Promoting Digital Proficiency and Health Literacy in Middle-aged and Older Adults Through Mobile Devices With the Workshops for Online Technological Inclusion (OITO) Project: Experimental Study. JMIR Formative Research. 2023
- Immunological hyporesponsiveness in tuberculosis: The role of mycobacterial glycolipids. Frontiers in Immunology. 2022
- A protein signature associated with active tuberculosis identified by plasma profiling and network-based analysis. iScience. 2022
- Cellular Aging Secretes: a Comparison of Bone-Marrow-Derived and Induced Mesenchymal Stem Cells and Their Secretome Over Long-Term Culture. Stem Cell Reviews and Reports. 2022
- IL-10 Overexpression After BCG Vaccination Does Not Impair Control of Mycobacterium tuberculosis Infection.. Frontiers in Immunology. 2022
- Maternal vaccination against group B Streptococcus glyceraldehyde-3-phosphate dehydrogenase leads to gut dysbiosis in the offspring. Brain, Behavior, and Immunity. 2022
- Low Memory T Cells Blood Counts and High Naïve Regulatory T Cells Percentage at Relapsing Remitting Multiple Sclerosis Diagnosis. Frontiers in Immunology. 2022
- Age-Related Sexual Dimorphism on the Longitudinal Progression of Blood Immune Cells in BALB/cByJ Mice. Journals of Gerontology Series A-Biological Sciences and Medical Sciences. 2022
- Intra-urban variation in tuberculosis and community socioeconomic deprivation in Lisbon metropolitan area: a Bayesian approach. Infectious Diseases of Poverty. 2022
- Increased Gal-3BP plasma levels in hospitalized patients infected with SARS-CoV-2. Clinical and Experimental Medicine. 2022
- Impact of inflammation on chronic limb-threatening ischaemia 2022
- Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomes. European Thyroid Journal. 2022
- IFNg and iNOS-Mediated Alterations in the Bone Marrow and Thymus and Its Impact on Mycobacterium avium-Induced Thymic Atrophy. Frontiers in Immunology. 2021
- Dysregulation of glycerophospholipid metabolism during Behçet's disease contributes to a pro-inflammatory phenotype of circulating monocytes. Emerging Microbes & Infections. 2021
- High Dimensional Immune Profiling Reveals Different Response Patterns in Active and Latent Tuberculosis Following Stimulation With Mycobacterial Glycolipids. Frontiers in Immunology. 2021
- Early IL-10 promotes vasculature associated CD4+ T cells unable to control Mycobacterium tuberculosis infection. JCI Insight. 2021
- Sorting Out Sorting Nexins Functions in the Nervous System in Health and Disease. Molecular Neurobiology. 2021
- Evaluation of drug-resistant tuberculosis treatment outcome in Portugal, 2000-2016. Antibiotics. 2021
- Splenic sympathetic signaling contributes to acute neutrophil infiltration of the injured spinal cord. Journal of Neuroinflammation. 2020
- Using Bayesian spatial models to map and to identify geographical hotspots of multidrug-resistant tuberculosis in Portugal between 2000 and 2016. Acta Cytologica. 2020
- Impact of iodine supplementation during preconception, pregnancy and lactation on maternal thyroid homeostasis and offspring psychomotor development: protocol of the IodineMinho prospective study. Arquivos de Medicina. 2020
- Editorial: Mycobacterial Glycolipids—Role in Immunomodulation and Targets for Vaccine Development. Frontiers in Immunology. 2020
- Cognition Is Associated With Peripheral Immune Molecules in Healthy Older Adults: A Cross-Sectional Study. Frontiers in Immunology. 2020
- CD4+ T cell proliferative responses to PPD and CFP-10 associate with recent M. tuberculosis infection. Tuberculosis. 2020
- Implications of SARS-CoV-2 evolution in the sensitivity of reverse-transcriptase quantitative PCR diagnostic assays. Lancet Infectious Diseases. 2020
- Stabilization of blood for long-term storage can affect antibody-based recognition of cell surface markers. Journal of Immunological Methods. 2020
- Implication of SARS-CoV-2 evolution in the sensitivity of RT-qPCR diagnostic assays. Lancet Infectious Diseases. 2020
- Loss of Resistance to Mousepox during Chronic Lymphocytic Choriomeningitis Virus Infection Is Associated with Impaired T-Cell Responses and Can Be Rescued by Immunization. Journal of Virology. 2019
- Chronic Lymphocytic Choriomeningitis Infection Causes Susceptibility to Mousepox and Impairs Natural Killer Cell Maturation and Function. Journal of Virology. 2019
- A nationwide study of multidrug-resistant tuberculosis in Portugal 2014-2017 using epidemiological and molecular clustering analyses. BMC Infectious Diseases. 2019
- Lipoarabinomannan in Active and Passive Protection Against Tuberculosis. Frontiers in Immunology. 2019
- Thymic Function as a Predictor of Immune Recovery in Chronically HIV-Infected Patients Initiating Antiretroviral Therapy. Frontiers in Immunology. 2019
- A complex scenario of tuberculosis transmission is revealed through genetic and epidemiological surveys in Porto. BMC Infectious Diseases. 2018
- A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection. Nature Communications. 2018
- Genetic diversity and potential routes of transmission of Mycobacterium bovis in Mozambique. PLoS Neglected Tropical Diseases. 2018
- Spatial Analysis of Wildlife Tuberculosis Based on a Serologic Survey Using Dried Blood Spots, Portugal. Emerging Infectious Diseases. 2018
- Prevalence and factors associated with diabetes mellitus among tuberculosis patients: a nationwide cohort.. European Respiratory Journal. 2016
- Absence of IFN gamma promotes hippocampal plasticity and enhances cognitive performance. Elife. 2016
- Understanding how infection of the thymus renders newly differentiated T cells tolerant to mycobacteria-specific antigens. European Journal of Immunology. 2016
- Analysis of a Local HIV-1 Epidemic in Portugal Highlights Established Transmission of Non-B and Non-G Subtypes. J. Clin. Microbiol.. 2015
- Artificial Thymus: A Tissue Engineering Strategy. Tissue Engineering. Part C: Methods. 2015
- Multiple Sclerosis: studying lipocalin 2 as a novel player in the pathophysiology of the disease. Glia. 2015
- Proteolytic systems and AMP-activated protein kinase are critical targets of acute myeloid leukemia therapeutic approaches. Oncotarget. 2015
- Absence of IFN-gamma leads to an enhanced cognitive phenotype. Journal of Neuroimmunology. 2014
- Cognitive performance among older individuals associated with the peripheral effector memory CD4+ T cells. Journal of Neuroimmunology. 2014
- Point-of-Care Testing device for analysis of Diabetes Mellitus. 3rd Portuguese Bioengineering Meeting, ENBENG 2013 - Book of Proceedings. 2013
- BCG vaccination inducing long-term protection against Mycobacterium tuberculosis correlates with the differentiation of IL-17/IL-2/TNF producing T cells. Immunology. 2012
- How "Humane" Is Your Endpoint?-Refining the Science-Driven Approach for Termination of Animal Studies of Chronic Infection. PLoS Pathogens. 2012
- ANTIBODY-MEDIATED NEUTRALIZATION OF BACTERIAL GAPDH PREVENTS NEONATAL DISEASE CAUSED BY GROUP B STREPTOCOCCUS. Intensive Care Medicine. 2011
- Brain Barriers and the Acute-Phase Response. Acute Phase Proteins - Regulation and Functions of Acute Phase Proteins. 2011
- Diagnosis of Tuberculosis in the Wild Boar (Sus scrofa): A Comparison of Methods Applicable to Hunter-Harvested Animals. Antibiotics. 2010
- Fate analysis in the T cell lineage. Human Gene Therapy. 2009
- Glucocorticoids participate in the development of thymus atrophy found during infection with a virulent strain of Mycobacterium avium. Cytokine. 2009
- Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4(+) T cells. The Journal of Immunology. 2007
- IL-10 underlies distinct susceptibility of BALB/c and C57BL/6 mice to Mycobacterium avium infection and influences efficacy of antibiotic therapy. The Journal of Immunology. 2007
- Improvement of antimycobacterial therapy due to IL-10 activity blockage is strain dependent. Journal of Immunology. 2005
- Transferrin is required for early T-cell differentiation. Immunology. 2004
- The cytolytic activity of natural killer cells is not involved in the restriction of Mycobacterium avium growth. International Immunology. 2003
- A molecular chart of thymocyte positive selection. European Journal of Immunology. 2001
- The shaping of the T cell repertoire. Immunity. 2001
- Amino acids specifying MHC class preference in TCR V alpha 2 regions. The Journal of Immunology. 1999
- CD4/CD8 lineage commitment: matching fate with competence. Immunological Reviews. 1998
- Visualization of CD4/CD8 T cell commitment. Journal of Experimental Medicine. 1998
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artigo de conferência
- Point-of-Care Testing device for Diabetes Mellitus and Renal Function analysis of biological fluids. Procedia Engineering. 2012
- 197. Behavioral alterations caused by Mycobacterium avium chronic infection are mouse strain dependent 2011
- 219. Iron-related proteins in the CSF of early multiple sclerosis patients 2011
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artigo de revista
- The Influence of Feeder Cell-Derived Extracellular Matrix Density on Thymic Epithelial Cell Culture. ACS Biomaterials Science and Engineering. 2023
- People with Primary Progressive Multiple Sclerosis Have a Lower Number of Central Memory T Cells and HLA-DR+ Tregs. Cells. 2023
- Fibronectin-Functionalized Fibrous Meshes as a Substrate to Support Cultures of Thymic Epithelial Cells. Biomacromolecules. 2020
- Phylogeography of 27,000 SARS-CoV-2 Genomes: Europe as the Major Source of the COVID-19 Pandemic. Antibiotics. 2020
- Quantification of the Animal Tuberculosis Multi-Host Community Offers Insights for Control. Pathogens. 2020
- Evolutionary analysis of Mycobacterium bovis genotypes across Africa suggests co-evolution with livestock and humans. PLoS Neglected Tropical Diseases. 2020
- A new mathematical model to identify contacts with recent and remote latent tuberculosis. Erj Open Research. 2019
- Biomarkers for tuberculosis: the case for lipoarabinomannan. Erj Open Research. 2019
- Association of Leukotriene A4 Hydrolase with Tuberculosis Susceptibility Using Genomic Data in Portugal. Antibiotics. 2019
- Definition of Immunological Nonresponse to Antiretroviral Therapy. Jaids-Journal of Acquired Immune Deficiency Syndromes. 2019
- Ag85-focused T-cell immune response controls Mycobacterium avium chronic infection. Antibiotics. 2018
- Immune Thymic Profile of the MOG-Induced Experimental Autoimmune Encephalomyelitis Mouse Model. Frontiers in Immunology. 2018
- Lipocalin-2 regulates adult neurogenesis and contextual discriminative behaviours. Elife. 2018
- Sorting nexin 3 mutation impairs development and neuronal function in Caenorhabditis elegans. Cellular and Molecular Life Sciences. 2018
- The choroid plexus in health and in disease: dialogues into and out of the brain. Neurobiology of Disease. 2017
- Microfluidic immunosensor for rapid and highly-sensitive salivary cortisol quantification. Biosensors & Bioelectronics. 2017
- Effect of blood type on anti-a-Gal immunity and the incidence of infectious diseases.. Experimental and Molecular Medicine. 2017
- Tuberculosis among the homeless: should we change the strategy?. International Journal of Tuberculosis and Lung Disease. 2017
- Brain interference: Revisiting the role of IFN gamma in the central nervous system. Elife. 2017
- How age, sex and genotype shape the stress response. Neurobiology of Stress. 2017
- Toxoplasmosis-associated IRIS involving the CNS: A case report with longitudinal analysis of T cell subsets. BMC Infectious Diseases. 2017
- Absence of IFNgamma promotes hippocampal plasticity and enhances cognitive performance. Elife. 2016
- Adult Body Height Is a Good Predictor of Different Dimensions of Cognitive Function in Aged Individuals: A Cross-Sectional Study. Frontiers in Aging Neuroscience. 2016
- Insights on the pathophysiology of Alzheimer's disease: The crosstalk between amyloid pathology, neuroinflammation and the peripheral immune system. Neuroscience and Biobehavioral Reviews. 2016
- Lipoarabinomannan, and its related glycolipids, induce divergent and opposing immune responses to Mycobacterium tuberculosis depending on structural diversity and experimental variations. Tuberculosis. 2016
- Longitudinal evaluation of regulatory T-cell dynamics on HIV-infected individuals during the first 2 years of therapy. AIDS. 2016
- The looming tide of nontuberculous mycobacterial infections in Portugal and Brazil. Tuberculosis. 2016
- Exploring Female Mice Interstrain Differences Relevant for Models of Depression. Acta Cytologica. 2015
- From the periphery to the brain: Lipocalin-2, a friend or foe?. Elife. 2015
- Analysis of a Local HIV-1 Epidemic in Portugal Highlights Established Transmission of non-B and -G Subtypes. Journal of Clinical Microbiology. 2015
- Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection.. PLoS Pathogens. 2015
- Effector memory CD4(+) T cells are associated with cognitive performance in a senior population. Neurology: Neuroimmunology and Neuroinflammation. 2015
- Tuberculosis and HIV Coinfection.. Cold Spring Harbor Perspectives in Medicine. 2015
- An efficient chronic unpredictable stress protocol to induce stress-relatec responses in C57BL/6 mice. Frontiers in Psychiatry. 2015
- BCG vaccination-induced long-lasting control of Mycobacterium tuberculosis correlates with the accumulation of a novel population of CD4<sup>+</sup>IL-17<sup>+</sup>TNF<sup>+</sup>IL-2<sup>+</sup> T cells. Vaccine. 2015
- Mycobacterium tuberculosis causing tuberculous lymphadenitis in Maputo, Mozambique. BMC Microbiology. 2015
- Patterns of Mycobacterium tuberculosis-complex excretion and characterization of super-shedders in naturally-infected wild boar and red deer. Veterinary Research. 2015
- The Warburg effect in mycobacterial granulomas is dependent on the recruitment and activation of macrophages by gamma interferon.. Immunology. 2015
- The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer's disease. Brain, Behavior, and Immunity. 2015
- To Be or Not to Be a Pseudogene: A Molecular Epidemiological Approach to the mclx Genes and Its Impact in Tuberculosis. Antibiotics. 2015
- Widespread Environmental Contamination with Mycobacterium tuberculosis Complex Revealed by a Molecular Detection Protocol. Antibiotics. 2015
- Lipocalin 2 modulates the cellular response to amyloid beta. Cell Death and Differentiation. 2014
- Prevalence of Bovine Tuberculosis and Risk Factor Assessment in Cattle in Rural Livestock Areas of Govuro District in the Southeast of Mozambique. Antibiotics. 2014
- The behavioral and immunological impact of maternal separation: A matter of timing. Acta Cytologica. 2014
- Lipocalin-2 is involved in emotional behaviors and cognitive function. Frontiers in Cellular Neuroscience. 2013
- Poor Immune Reconstitution in HIV-Infected Patients Associates with High Percentage of Regulatory CD4(+) T Cells. Antibiotics. 2013
- T Cells Home to the Thymus and Control Infection. Journal of Immunology. 2013
- TLR2-Induced IL-10 Production Impairs Neutrophil Recruitment to Infected Tissues during Neonatal Bacterial Sepsis. The Journal of Immunology. 2013
- Tolerance has its limits: How the thymus copes with infection. Trends in Immunology. 2013
- A Walk into the LuxR Regulators of Actinobacteria: Phylogenomic Distribution and Functional Diversity. Antibiotics. 2012
- A case-control study on the diagnostic potential of multi-antigen serological tests for tuberculosis. Archives of Clinical Microbiology. 2012
- Animal Welfare in Studies on Murine Tuberculosis: Assessing Progress over a 12-Year Period and the Need for Further Improvement. Antibiotics. 2012
- Diagnosis of Mycobacterium avium Complex in Granulomatous Lymphadenitis in Slaughtered Domestic Pigs. Journal of Comparative Pathology. 2012
- Lipocalin 2 is present in the EAE brain and is modulated by natalizumab. Frontiers in Cellular Neuroscience. 2012
- Modulation of iron metabolism in aging and in Alzheimer's disease: Relevance of the choroid plexus. Frontiers in Cellular Neuroscience. 2012
- Molecular and Cellular Mechanisms of Mycobacterium avium-Induced Thymic Atrophy. The Journal of Immunology. 2012
- Neutrophils and macrophages: The main partners of phagocyte cell systems. Frontiers in Immunology. 2012
- Inhibition of IL-10 production by maternal antibodies against group b streptococcus GAPDH confers immunity to offspring by favoring neutrophil recruitment. PLoS Pathogens. 2011
- Interplay between depressive-like behavior and the immune system in an animal model of prenatal dexamethasone administration. Acta Cytologica. 2011
- Mycobacteria-induced anaemia revisited: A molecular approach reveals the involvement of NRAMP1 and lipocalin-2, but not of hepcidin. Immunobiology. 2011
- Transcriptome signature of the adult mouse choroid plexus. Fluids and Barriers of the Cns. 2011
- Motor uncoordination and neuropathology in a transgenic mouse model of Machado-Joseph disease lacking intranuclear inclusions and ataxin-3 cleavage products. Neurobiology of Disease. 2010
- Influenza Infectious Dose May Explain the High Mortality of the Second and Third Wave of 1918–1919 Influenza Pandemic. Antibiotics. 2010
- Dissemination of mycobacteria to the thymus renders newly generated T cells tolerant to the invading pathogen. Journal of Immunology. 2010
- Environmental Enrichment does not Compromise the Immune Response in Mice Chronically Infected with Mycobacterium avium. Scandinavian Journal of Immunology. 2010
- The choroid plexus response to a repeated peripheral inflammatory stimulus. BMC Neuroscience. 2009
- Epidemiology of Mycobacterium bovis infection in wild boar (Sus scrofa) from Portugal.. Journal of Wildlife Diseases. 2009
- Kinetic Profile of the Transcriptome Changes Induced in the Choroid Plexus by Peripheral Inflammation. Journal of Cerebral Blood Flow & Metabolism. 2009
- Altered Iron Metabolism Is Part of the Choroid Plexus Response to Peripheral Inflammation. Endocrinology. 2009
- Interleukin-10: A Key Cytokine in Depression?. Cardiovascular Psychiatry and Neurology. 2009
- Recruitment of Antigen-Specific CD8(+) T Cells in Response to Infection Is Markedly Efficient. Science. 2009
- Animal-side serologic assay for rapid detection of Mycobacterium bovis infection in multiple species of free-ranging wildlife. Veterinary Microbiology. 2008
- IL-10 modulates depressive-like behavior. Journal of Psychiatric Research. 2008
- Lipocalin 2 is a choroid plexus acute-phase protein. Journal of Cerebral Blood Flow & Metabolism. 2008
- The thymus as a target for mycobacterial infections. Microbes and Infection. 2007
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capítulo de livro
- Evolution and Molecular Characteristics of Mycobacterium tuberculosis and Mycobacterium bovis 2023
- Aetiopathogenesis, immunology and microbiology 2018
- O Centro de Competências Laboratoriais: Um novo modelo para aprendizagem de competências laboratoriais. 2013
- Wildlife Tuberculosis: A Systematic Review of the Epidemiology in Iberian Peninsula. 2012
- Brain Barriers and the Acute-Phase Response, Acute Phase Proteins - Regulation and Functions of Acute Phase Proteins. 2011
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documento
- Atitudes e comportamentos associados à transmissão do VIH nos homens que fazem sexo com homens (HSH) – um estudo qualitativo 2024
- SNX27 Ubiquitous and Hippocampal-Specific Deletion Impairs Cognitive Function 2023
- Studying the effects of interleukin-10 absence on the hypothalamic-pituitary-adrenal axis 2020
- The anti-inflammatory cytokine interleukin-10 as a novel player in cognitive function 2020
- Mortality and associated factors among drug-resistant tuberculosis patients in Portugal, 2000-2016 2020
- Cognitive performance: exploring the role of interleukin-10 in male mice 2019
- Deciphering the mechanisms underlying the role of interleukin-10 in cognitive function 2019
- WHO Guideline: Portugal: Towards TB elimination: how to reach the homeless population in urban centres? 2019
- Exploring Sorting Nexin 27 role in Pain 2017
- Immune profile characterization of an Alzheimer¿s disease mice model 2017
- Student success and perception of subject knowledge of an integrated course on the essentials of disease and treatment 2016
- An integrated course on the essential concepts of disease and treatment: longitudinal findings on acceptability and retention of disciplinary knowledge 2016
- Artificial thymus: a tissue engineering strategy. International Review of Neurobiology. 2015
- Learning bacterial identification in infectious disease using a laboratory guided discovery approach 2015
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livro