publicações selecionadas
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artigo académico
- Intratumoral Fusobacterium nucleatum is associated with better cancer-specific survival in head and neck cancer patients. Journal of Oral Microbiology. 2025
- KRAS-G12C: The neglected biomarker to detect patients with MUTYH-associated polyposis. International Journal of Cancer. 2025
- An integrated approach to molecular profiling supports precision diagnosis of pediatric medulloblastoma in Argentina amid the resource-constrained setting.. Acta Cytologica. 2025
- Exploring shared microRNA profiles in liquid-based cytology and plasma as biomarkers of high-grade intraepithelial lesions.. Acta Cytologica. 2025
- Hybrid Dihydropyrimidinones Targeting AKT Signaling: Antitumor Activity in Hormone-Dependent 2D and 3D Cancer Models. Pharmaceutics. 2025
- A Systematic Study of Molecular Diagnosis, Treatment and Prognosis in Infant-Type Hemispheric Glioma): An Individual Patient Data Meta-analysis of 164 patients. Neuro-Oncology. 2025
- Comparative evaluation of microRNA detection in plasma, urine and liquid-based cytology for high-grade cervical intraepithelial neoplasia.. Oncology Letters. 2025
- E6/E7 Similarity to Human Papillomavirus Prototypes and Performance of HPV Testing by Cobas 4800 HPV Test and Anyplex II HPV HR.. Journal of Medical Virology. 2025
- Patient-Reported Outcomes and Experiences Following Robotic, Laparoscopic, and Open Surgery for Endometrial Cancer. International Journal of Gynecological Cancer. 2025
- Teleconsultation for Delivering Low-Dose Computed Tomography Reports in a Mobile Lung Cancer Screening Program in a Low- and Middle-Income Country: A Cross-Sectional Study. . Cancer control : journal of the Moffitt Cancer Center. 2025
- Cross-ancestral GWAS identifies 29 variants across head and neck cancer subsites.. Nature Communications. 2025
- Feasibility of a ctDNA multigenic panel for non-small-cell lung cancer early detection and disease surveillance. . Molecular Oncology. 2025
- Using Mendelian randomization to investigate etiologic heterogeneity across renal cell carcinoma subtypes.. International Journal of Epidemiology. 2025
- Design, synthesis and evaluation of fluorescent dihydropyridine-dihydropyrimidinone hybrids as inducers of cell-cycle arrest in a prostate cancer cell line <i>via</i> Aurora kinase interactions.. RSC Medicinal Chemistry. 2025
- Expression of programmed cell death ligand 1 protein and other biomarkers in patients with gastric cancer and gastroesophageal junction cancer: a retrospective single centre study in Brazil.. Frontiers in Oncology. 2025
- Establishment and molecular profiling of a PDX model of a metachronous brain tumor in a patient with constitutional mismatch repair deficiency with biallelic MSH6 variant.. Animal models and experimental medicine. 2025
- Rare intra-tumoral colonization of Fusobacterium nucleatum in endometrial cancer. International Journal of Gynecological Cancer. 2025
- Whole-exome sequencing identifies new pathogenic germline variants in patients with colorectal polyposis.. World Journal of Gastroenterology. 2025
- RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR-targeted therapies. Molecular Oncology. 2025
- Comparative performance of cobas 4800 HPV Test and Anyplex II HPV HR for high-risk human papillomavirus detection.. Journal of Clinical Microbiology. 2025
- Association of Genetic Ancestry and Colorectal Cancer Risk in a Large Brazilian Cohort: Replication of Single-Nucleotide Polymorphisms Identified by Genome-Wide Association Studies.. JCO Global Oncology. 2025
- Immune profiling of pediatric germ cell tumors identifies key cell populations and novel therapeutic targets.. Frontiers in Immunology. 2025
- Exploring the Nottingham classification: assessing gene expression profiles in breast cancer patients and their association with outcomes.. Breast Cancer Research and Treatment. 2025
- High B7-H3 protein expression in Medulloblastoma is associated with metastasis and unfavorable patient outcomes. Diagnostic Pathology. 2025
- Geographic and age variations in mutational processes in colorectal cancer.. Nature. 2025
- The complexity of tobacco smoke-induced mutagenesis in head and neck cancer. Nature Genetics. 2025
- Worldwide Innovative Network (WIN) Consortium in Personalized Cancer Medicine: Bringing next-generation precision oncology to patients.. Oncotarget. 2025
- Advanced Stage Head and Neck Cancer Diagnosis: HEADSpAcE Consortium Health Systems Benchmarking Survey.. Head and Neck. 2025
- HOXA9 methylation is not associated with survival in Brazilian patients with lung adenocarcinoma.. Clinical Epigenetics. 2025
- Nose-to-Brain Delivery of Biomimetic Nanoparticles for Glioblastoma Targeted Therapy. ACS Applied Materials and Interfaces. 2025
- Enhancing precision in sarcoma diagnosis: nCounter fusion panel implementation in a middle-income country. Therapeutic Advances in Medical Oncology. 2025
- Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-mediated signaling.. Frontiers in Molecular Biosciences. 2025
- Implementation of the ProMisE classifier and validation of its prognostic impact in Brazilian endometrial carcinomas.. Frontiers in Oncology. 2024
- Evaluation of the antineoplastic properties of the photosensitizer biscyanine in 2D and 3D tumor cell models and artificial skin models.. Journal of photochemistry and photobiology. B, Biology. 2024
- Plasma mutation profile of precursor lesions and colorectal cancer using the Oncomine Colon cfDNA Assay.. BMC Cancer. 2024
- Association of Fusobacterium nucleatum Levels by ddPCR in Oral Rinse Samples With Periodontal Disease in Oral Squamous Cell Carcinoma Patients and in Controls. Journal of Oral Pathology & Medicine. 2024
- Cisplatin-resistant germ cell tumor models: An exploration of the epithelial-mesenchymal transition regulator SLUG.. Molecular Medicine Reports. 2024
- Randomized experimental population-based study to evaluate the acceptance and completion of and preferences for cervical cancer screening 2024
- Immune-checkpoint gene expression and BCG response in non-muscle invasive bladder cancer. Translational Oncology. 2024
- Transcriptome- and proteome-wide association studies identify genes associated with renal cell carcinoma. American Journal of Human Genetics. 2024
- Correction: Alves et al. WNK2 Inhibits Autophagic Flux in Human Glioblastoma Cell Line. Cells 2020, 9, 485. Cells. 2024
- Enhancing Colorectal Cancer Screening with Droplet Digital PCR (ddPCR) Analysis of Fusobacterium nucleatum in Fecal Immunochemical Test (FIT) Samples. Acta Cytologica. 2024
- EV-miRNAs from breast cancer patients of plasma as potential prognostic biomarkers of disease recurrence. Heliyon. 2024
- Unveiling the RKIP and EGFR Inverse Relationship in Solid Tumors: A Case Study in Cervical Cancer. Cancers. 2024
- Comprehensive microRNA expression analysis of pediatric gonadal germ cell tumors: unveiling novel biomarkers and signatures. . Molecular Oncology. 2024
- Geographic variation of mutagenic exposures in kidney cancer genomes.. Nature. 2024
- Somatic mutational profiling and clinical impact of driver genes in Latin-Iberian medulloblastomas: Towards precision medicine.. Neuropathology : official journal of the Japanese Society of Neuropathology. 2024
- Establishment and molecular characterization of HCB-541, a novel and aggressive human cutaneous squamous cell carcinoma cell line.. Human Cell. 2024
- Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions.. Nature Genetics. 2024
- SERS sensing for cancer biomarker: Approaches and directions. Bioactive Materials. 2024
- Glucose Metabolism as a Potential Therapeutic Target in Cytarabine-Resistant Acute Myeloid Leukemia. Pharmaceutics. 2024
- PD-L1 expression and microsatellite instability (MSI) in cancer of unknown primary site.. International Journal of Clinical Oncology. 2024
- The Mutographs biorepository: A unique genomic resource to study cancer around the world. Cell Genomics. 2024
- Gene expression profiles (GEPs) of immuno-oncologic pathways as predictors of response to checkpoint inhibitors in advanced NSCLC. Translational Oncology. 2024
- Unveiling the role of MGMT and DAPK hypermethylation in response to anti-EGFR agents: Molecular insights for advancing HNSCC treatment. Head and Neck. 2023
- RAD50 Deficient in a Breast Cancer Model Predicts Sensitivity to PARP Inhibitors. Current Cancer Drug Targets. 2023
- Unsupervised machine learning models reveal predictive clinical markers of glioblastoma patient survival using white blood cell counts prior to initiating chemoradiation. Neuro-Oncology Advances. 2023
- Low EGFL7 expression is associated with high lymph node spread and invasion of lymphatic vessels in colorectal cancer.. Acta Cytologica. 2023
- Biological and therapeutic implications of RKIP in Gastrointestinal Stromal Tumor (GIST): an integrated transcriptomic and proteomic analysis. Cancer Cell International. 2023
- Absolute telomere length in peripheral blood lymphocytes of workers exposed to construction environment. International Journal of Environmental Health Research. 2023
- Hazard assessment of antineoplastic drugs and metabolites using cytotoxicity and genotoxicity assays.. Mutation research. Genetic toxicology and environmental mutagenesis. 2023
- Tapirira guianensis is Selectively Cytotoxic, Induces Apoptosis to the Glioblastoma and Decreases Tumor Growth and Angiogenesis in vivo.. Planta Medica. 2023
- Association between duration of smoking abstinence before non-small-cell lung cancer diagnosis and survival: a retrospective, pooled analysis of cohort studies. . The Lancet. Public health. 2023
- High frequency of WNT-activated medulloblastomas with CTNNB1 wild type suggests a higher proportion of hereditary cases in a Latin-Iberian population.. Frontiers in Oncology. 2023
- Combined SEPT9 and BMP3 methylation in plasma for colorectal cancer early detection and screening in a Brazilian population. Cancer Medicine. 2023
- Overall Survival, BRAF, RAS, and MSI Status in Patients Who Underwent Cetuximab After Refractory Chemotherapy for Metastatic Colorectal Cancer.. Journal of Gastrointestinal Cancer. 2023
- Biomarkers for Immune Checkpoint Inhibitor Response in NSCLC: Current Developments and Applicability. International Journal of Molecular Sciences. 2023
- Identification of MicroRNA Expression Profiles Related to the Aggressiveness of Salivary Gland Adenoid Cystic Carcinomas. Genes. 2023
- The Usefulness of an Online Simplified Screening Questionnaire (SSQ) in Identifying Work-Related Cancers. Healthcare. 2023
- Disclosing quantitative RT-PCR raw data during manuscript submission: a call for action. Molecular Oncology. 2023
- Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization. International Journal of Molecular Sciences. 2023
- Acetogenins-Rich Fractions of Annona coriacea Suppress Human Glioblastoma Viability and Migration by Regulating Necroptosis and MMP-2 Activity In Vitro. Biomolecules. 2023
- Disruptive and truncating TP53 mutations are associated with African-ancestry and worse prognosis in Brazilian patients with lung adenocarcinoma.. Pathobiology : journal of immunopathology, molecular and cellular biology. 2023
- Genetic ancestry of 1.127 Brazilian breast cancer patients and its correlation with molecular subtype and geographic region. Clinical Breast Cancer. 2023
- MicroRNA-130a-3p inhibition suppresses cervical cancer cell progression.. Oncology Reports. 2023
- PD-L1 and MCL-1 markers and the relationship with prognostic characteristics of differentiated thyroid carcinoma.. Molecular and Cellular Endocrinology. 2023
- The digital expression profile of BMP7, CDKN2C, HIST1H3G, and PKMYT1 genes improves high-grade cervical lesion detection in liquid-based cytology. 2023
- Extremely aggressive course in a poorly differentiated thyroid carcinoma presenting a double mutation of the TERT promoter.. The American journal of the medical sciences. 2023
- Somatic mutation detection and KRAS amplification in testicular germ cell tumors.. Frontiers in Oncology. 2023
- Digital expression profile of immune checkpoint genes in medulloblastomas identifies CD24 and CD276 as putative immunotherapy targets. . Frontiers in Immunology. 2023
- Bio-Prospecting of Crude Leaf Extracts from Thirteen Plants of Brazilian Cerrado Biome on Human Glioma Cell Lines. Biomolecules. 2023
- Genomic profile of two Brazilian choroid plexus tumors by whole-exome sequencing.. Cold Spring Harbor molecular case studies. 2023
- Using design of experiments (DoE) to optimize performance and stability of biomimetic cell membrane-coated nanostructures for cancer therapy.. Frontiers in Bioengineering and Biotechnology. 2023
- Liquid Biopsy for Lung Cancer: Up-to-Date and Perspectives for Screening Programs. International Journal of Molecular Sciences. 2023
- Ancestry and self-reported race in Brazilian breast cancer women. Revista da Associacao Medica Brasileira. 2023
- Cancer immune profiling unveils biomarkers, immunological pathways, and cell type score associated with glioblastoma patients' survival.. Therapeutic Advances in Medical Oncology. 2022
- Respiratory and cardiometabolic comorbidities and Stage I-III non-small cell lung cancer (NSCLC) survival: A pooled analysis from the International Lung Cancer Consortium (ILCCO). . Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2022
- Significance of Chr9p22.1-p21.3 Deletion in Cancer Development: A Pan-cancer In Silico Analysis.. Anticancer Research. 2022
- The Barretos Cancer Hospital Animal Facility: Implementation and Results of a Dedicated Platform for Preclinical Oncology Models.. Veterinary Sciences. 2022
- A Screening of Epigenetic Therapeutic Targets for Non-Small Cell Lung Cancer Reveals PADI4 and KDM6B as Promising Candidates. International Journal of Molecular Sciences. 2022
- ERBB2 exon 20 insertions are rare in Brazilian non-small cell lung cancer.. Thoracic Cancer. 2022
- EGFR Mutations and PD-L1 Expression in Early-Stage Non-Small Cell Lung Cancer: A Real-World Data From a Single Center in Brazil. . The oncologist. 2022
- Whole-Exome Sequencing Identifies Pathogenic Germline Variants in Patients with Lynch-Like Syndrome. Cancers. 2022
- Role of Polygenic Risk Score in Cancer Precision Medicine of Non-European Populations: A Systematic Review. Current Oncology. 2022
- Matteucinol combined with temozolomide inhibits glioblastoma proliferation, invasion, and progression: an in vitro, in silico, and in vivo study.. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. 2022
- Potential New Therapeutic Approaches for Cisplatin-Resistant Testicular Germ Cell Tumors.. Frontiers in bioscience (Landmark edition). 2022
- Viral Encoded miRNAs in Tumorigenesis: Theranostic Opportunities in Precision Oncology. African Journal of Biotechnology. 2022
- Cutaneous and acral melanoma cross-OMICs reveals prognostic cancer drivers associated with pathobiology and ultraviolet exposure. Nature Communications. 2022
- Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines. International Journal of Molecular Sciences. 2022
- Cost-Effectiveness of BRCA 1/2 Genetic Test and Preventive Strategies: Using Real-World Data From an Upper-Middle Income Country.. Frontiers in Oncology. 2022
- The Role of Ingenane Diterpenes in Cancer Therapy: From Bioactive Secondary Compounds to Small Molecules. Natural Product Communications. 2022
- Somatic targeted mutation profiling of colorectal cancer precursor lesions. BMC Medical Genomics. 2022
- Upregulated miRNAs on the TP53 and RB1 Binding Seedless Regions in High-Risk HPV-Associated Penile Cancer. Frontiers in Genetics. 2022
- NTRK2 gene fusions are uncommon in pilocytic astrocytoma. Molecular Biology Reports. 2022
- EGFL7 expression profile in IDH-wildtype glioblastomas is associated with poor patient outcome. Journal of Pathology and Translational Medicine. 2022
- Does a Multiple Myeloma Polygenic Risk Score Predict Overall Survival of Myeloma Patients?. Cancer Epidemiology Biomarkers & Prevention. 2022
- African genetic ancestry is associated with lower frequency of PNPLA3 G allele in non-alcoholic fatty liver in an admixed population. Annals of Hepatology. 2022
- Genomic instability evaluation by BMCyt and telomere length in Brazilian family farmers exposed to pesticides. Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 2022
- The Antitumoral/Antimetastatic Action of the Flavonoid Brachydin A in Metastatic Prostate Tumor Spheroids In Vitro Is Mediated by (Parthanatos) PARP-Related Cell Death. Pharmaceutics. 2022
- Association of microsatellite instability (MSI) status with the 5-year outcome and genetic ancestry in a large Brazilian cohort of colorectal cancer. European Journal of Human Genetics. 2022
- Histological Biomarkers and Protein Expression in Hyphessobrycon eques Fish Exposed to Atrazine. Water, Air, and Soil Pollution. 2022
- Socioeconomic, Clinical, and Molecular Features of Breast Cancer Influence Overall Survival of Latin American Women.. Frontiers in Oncology. 2022
- The Transcriptomic Portrait of Locally Advanced Breast Cancer and Its Prognostic Value in a Multi-Country Cohort of Latin American Patients.. Frontiers in Oncology. 2022
- New insights on familial colorectal cancer type X syndrome. Acta Cytologica. 2022
- Single nCounter assay for prediction of MYCN amplification and molecular classification of medulloblastomas: a multicentric study. Journal of Neuro-Oncology. 2022
- MicroRNA Interrelated Epithelial Mesenchymal Transition (EMT) in Glioblastoma. Genes. 2022
- A Unique Case Report of Infant-Type Hemispheric Glioma (Gliosarcoma Subtype) with TPR-NTRK1 Fusion Treated with Larotrectinib. Pathobiology. 2022
- Accounting for EGFR mutations in epidemiological analyses of non-small cell lung cancers: Examples based on the International Lung Cancer Consortium data. Cancer Epidemiology Biomarkers & Prevention. 2022
- Information theory approaches to improve glioma diagnostic workflows in surgical neuropathology. Brain Pathology. 2022
- Accuracy and Clinical Relevance of Intra-Tumoral Fusobacterium nucleatum Detection in Formalin-Fixed Paraffin-Embedded (FFPE) Tissue by Droplet Digital PCR (ddPCR) in Colorectal Cancer. Diagnostics. 2022
- Comprehensive Molecular Landscape of Cetuximab Resistance in Head and Neck Cancer Cell Lines. Cells. 2022
- Challenges of Implementing Lung Cancer Screening in a Developing Country: Results of the Second Brazilian Early Lung Cancer Screening Trial (BRELT2). JCO Global Oncology. 2022
- Low-cost bacterial nanocellulose-based interdigitated biosensor to detect the p53 cancer biomarker.. Materials science & engineering. C, Materials for biological applications. 2022
- A computational approach for the discovery of significant cancer genes by weighted mutation and asymmetric spreading strength in networks. Acta Cytologica. 2021
- Profile of esophageal squamous cell carcinoma mutations in Brazilian patients. Acta Cytologica. 2021
- Microsatellite Instability Is Rare in the Admixed Brazilian Population of Non-Small Cell Lung Cancer: A Cohort of 526 Cases. Pathobiology. 2021
- A polygenic risk score for multiple myeloma risk prediction.. European journal of human genetics : EJHG. 2021
- Frequency of Human Papillomavirus Detection in Chagasic Megaesophagus Associated or Not with Esophageal Squamous Cell Carcinoma.. Pathobiology : journal of immunopathology, molecular and cellular biology. 2021
- Decoding the Roles of Astrocytes and Hedgehog Signaling in Medulloblastoma. Current Oncology. 2021
- Methylation profile of colon cancer genes in colorectal precursor lesions and tumor tissue: perspectives for screening. Scandinavian Journal of Gastroenterology. 2021
- A 4-Gene Signature Associated With Recurrence in Low- and Intermediate-Risk Endometrial Cancer.. Frontiers in Oncology. 2021
- Reproduction of the Cancer Genome Atlas (TCGA) and Asian Cancer Research Group (ACRG) Gastric Cancer Molecular Classifications and Their Association with Clinicopathological Characteristics and Overall Survival in Moroccan Patients. Disease Markers. 2021
- MCT1 Is a New Prognostic Biomarker and Its Therapeutic Inhibition Boosts Response to Temozolomide in Human Glioblastoma. Cancers. 2021
- Clinical impact of brachyury expression in Ewing sarcoma patients.. Advances in Medical Sciences. 2021
- The biobank of barretos cancer hospital: 14 years of experience in cancer research.. Cell and Tissue Banking. 2021
- Correlation of p16 immunohistochemistry with clinical and epidemiological features in oropharyngeal squamous-cell carcinoma. 2021
- HPV-induced oropharyngeal squamous cell carcinomas in Brazil: prevalence, trend, clinical and epidemiological characterization.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2021
- Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study.. Lancet Oncology. 2021
- Nose-to-brain co-delivery of drugs for glioblastoma treatment using nanostructured system.. International Journal of Applied Pharmaceutics. 2021
- Adaptive epigenetic response of glutathione (GSH)-related genes against lead (Pb)-induced toxicity, in individuals chronically exposed to the metal. Chemosphere. 2021
- Frequency of KRAS p.Gly12Cys Mutation in Brazilian Patients With Lung Cancer.. JCO Global Oncology. 2021
- Genetically determined telomere length and multiple myeloma risk and outcome.. Blood Cancer Journal. 2021
- MicroRNA Biomarkers of High-Grade Cervical Intraepithelial Neoplasia in Liquid Biopsy.. Biomed Research International. 2021
- A Systematic Review of MicroRNAs Involved in Cervical Cancer Progression. Cells. 2021
- Bioprospecting of Natural Compounds from Brazilian Cerrado Biome Plants in Human Cervical Cancer Cell Lines. International Journal of Molecular Sciences. 2021
- Expression quantitative trait loci of genes predicting outcome are associated with survival of multiple myeloma patients.. International Journal of Cancer. 2021
- Role of glioblastoma stem cells in cancer therapeutic resistance: a perspective on antineoplastic agents from natural sources and chemical derivatives.. Stem Cell Research and Therapy. 2021
- PD-L1 expression by Tumor Proportion Score (TPS) and Combined Positive Score (CPS) are similar in non-small cell lung cancer (NSCLC). Journal of Clinical Pathology. 2021
- Clinicopathological and molecular characterization of Brazilian families at risk for Lynch syndrome. Cancer Genetics. 2021
- Evaluation of the prognostic potential of EGFL7 in pilocytic astrocytomas. Neuropathology. 2021
- Microsatellite Instability Analysis in Gastric Carcinomas of Moroccan Patients. Genetic Testing and Molecular Biomarkers. 2021
- Somatic Copy Number Alterations and Associated Genes in Clear-Cell Renal-Cell Carcinoma in Brazilian Patients. International Journal of Molecular Sciences. 2021
- Integrated analysis of mRNA and miRNA profiles revealed the role of miR-193 and miR-210 as potential regulatory biomarkers in different molecular subtypes of breast cancer. BMC Cancer. 2021
- A PCR-Based Approach for Driver Mutation Analysis of EGFR, KRAS, and BRAF Genes in Lung Cancer Tissue Sections.. Methods in Molecular Biology. 2021
- Detection of anti-cancer drugs and metabolites in the effluents from a large Brazilian cancer hospital and an evaluation of ecotoxicology. Environmental Pollution. 2021
- Electrochemical and optical detection and machine learning applied to images of genosensors for diagnosis of prostate cancer with the biomarker PCA3. Talanta. 2021
- Low MGMT digital expression is associated with a better outcome of IDH1 wildtype glioblastomas treated with temozolomide. Journal of Neuro-Oncology. 2021
- Simultaneous analysis of ALK, RET, and ROS1 gene fusions by NanoString in Brazilian lung adenocarcinoma patients. Translational Lung Cancer Research. 2021
- Whole-exome sequencing of non- BRCA1/BRCA2 mutation carrier cases at high-risk for hereditary breast/ovarian cancer. Human Mutation. 2020
- Influence of the Molecular Orientation and Ionization of Self-Assembled Monolayers in Biosensors: Application to Genosensors of Prostate Cancer Antigen 3. Journal of Physical Chemistry C. 2020
- Modulating chitosan-PLGA nanoparticle properties to design a co-delivery platform for glioblastoma therapy intended for nose-to-brain route. Drug Delivery and Translational Research. 2020
- The Role of Fusobacterium nucleatum in Colorectal Carcinogenesis. Pathobiology. 2020
- Cell-free DNA promotes malignant transformation in non-tumor cells. Acta Cytologica. 2020
- Whole blood mRNA expression-based targets to discriminate active tuberculosis from latent infection and other pulmonary diseases. Acta Cytologica. 2020
- Human Papillomavirus DNA Detection by Droplet Digital PCR in Formalin-Fixed Paraffin-Embedded Tumor Tissue from Oropharyngeal Squamous Cell Carcinoma Patients. Molecular Diagnosis & Therapy. 2020
- Common gene variants within 3'-untranslated regions as modulators of multiple myeloma risk and survival. International Journal of Cancer. 2020
- Pyknon-Containing Transcripts Are Downregulated in Colorectal Cancer Tumors, and Loss of PYK44 Is Associated With Worse Patient Outcome. Frontiers in Genetics. 2020
- Multi-center real-world comparison of the fully automated Idylla™ microsatellite instability assay with routine molecular methods and immunohistochemistry on formalin-fixed paraffin-embedded tissue of colorectal cancer. Virchows Archiv. 2020
- The combination of coffee compounds attenuates early fibrosis-associated hepatocarcinogenesis in mice: involvement of miRNA profile modulation. Journal of Nutritional Biochemistry. 2020
- Circulating tumor DNA (ctDNA) detection is associated with shorter progression-free survival in advanced melanoma patients. Acta Cytologica. 2020
- Determination of p53 biomarker using an electrochemical immunoassay based on layer-by-layer films with NiFe2O4 nanoparticles. Microchimica Acta. 2020
- Deregulated microRNAs Are Associated with Patient Survival and Predicted to Target Genes That Modulate Lung Cancer Signaling Pathways. Cancers. 2020
- EGF +61 A>G polymorphism does not predict response to first-generation EGFR tyrosine kinase inhibitors in lung cancer patients. Thoracic Cancer. 2020
- The Performance of Colorectal Cancer Screening in Brazil: The First Two Years of the Implementation Program in Barretos Cancer Hospital. Acta Cytologica. 2020
- Brachyury Is Associated with Glioma Differentiation and Response to Temozolomide. Neurotherapeutics. 2020
- Universal cervical cancer control through a right to health lens: refocusing national policy and programmes on underserved women. BMC International Health and Human Rights. 2020
- TERT Promoter Mutation C228T Increases Risk for Tumor Recurrence and Death in Head and Neck Cancer Patients. Frontiers in Oncology. 2020
- A multinational review: Oesophageal cancer in low to middle-income countries (Review). Oncology Letters. 2020
- Feasibility of methylated ctDNA detection in plasma samples of oropharyngeal squamous cell carcinoma patients. Head and Neck. 2020
- Expression of GNAS, TP53, and PTEN Improves the Patient Prognostication in Sonic Hedgehog (SHH) Medulloblastoma Subgroup. Journal of Molecular Diagnostics. 2020
- Screen-printed electrodes modified with carbon black and polyelectrolyte films for determination of cancer marker carbohydrate antigen 19-9. Microchimica Acta. 2020
- Characterization of the in vitro cytotoxic effects of brachydins isolated from Fridericia platyphylla in a prostate cancer cell line. Journal of Toxicology and Environmental Health - Part A. 2020
- Cervical cancer in low and middle-income countries (Review). Oncology Letters. 2020
- Impact of genetic variants in clinical outcome of a cohort of patients with oropharyngeal squamous cell carcinoma. Acta Cytologica. 2020
- A novel molecular link between HOXA9 and WNT6 in glioblastoma identifies a subgroup of patients with particular poor prognosis. Molecular Oncology. 2020
- A 30-Year Long-Term Experience in Appendix Neuroendocrine Neoplasms—Granting a Positive Outcome. Cancers. 2020
- Immunosensors containing solution blow spun fibers of poly(lactic acid) to detect p53 biomarker. Packaging Technology and Science. 2020
- Ruthenium(II)/Benzonitrile Complex Induces Cytotoxic Effect in Sarcoma-180 Cells by Caspase-Mediated and Tp53/p21-Mediated Apoptosis, with Moderate Brine Shrimp Toxicity. Biological Trace Element Research. 2020
- The T-box transcription factor brachyury behaves as a tumor suppressor in gliomas. Journal of Pathology. 2020
- Comparative analysis of the dual EGFR-DNA targeting and growth inhibitory properties of 6-mono-alkylamino- and 6,6-dialkylaminoquinazoline-based type II combi-molecules. European Journal of Medicinal Chemistry. 2020
- Hypoxia and Macrophages Act in Concert Towards a Beneficial Outcome in Colon Cancer. Cancers. 2020
- Role of Genetic Ancestry in 1,002 Brazilian Colorectal Cancer Patients From Barretos Cancer Hospital.. Frontiers in Oncology. 2020
- miRNA expression profiling of hereditary breast tumors from BRCA1- and BRCA2-germline mutation carriers in Brazil. BMC Cancer. 2020
- Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness. Cells. 2020
- WNK2 Inhibits Autophagic Flux in Human Glioblastoma Cell Line. Cells. 2020
- Replication of GWAS identifies RTEL1, CDKN2A/B, and PHLDB1 SNPs as risk factors in Portuguese gliomas patients. Molecular Biology Reports. 2020
- Loss of SPINT2 expression frequently occurs in glioma, leading to increased growth and invasion via MMP2. Cellular Oncology. 2020
- Investigation of U-251 cell death triggered by flavonoid luteolin: towards a better understanding on its anticancer property against glioblastomas.. Natural Product Research. 2020
- Potential biomarkers of ductal carcinoma in situ progression.. BMC Cancer. 2020
- A novel strategy for glioblastoma treatment combining alpha-cyano-4-hydroxycinnamic acid with cetuximab using nanotechnology-based delivery systems. Drug Delivery and Translational Research. 2020
- Detection of HPV16 in cell lines deriving from cervical and head and neck cancer using a genosensor made with a DNA probe on a layer-by-layer matrix. Materials Chemistry Frontiers. 2020
- Mutational Profiling of Driver Tumor Suppressor and Oncogenic Genes in Brazilian Malignant Pleural Mesotheliomas. Pathobiology. 2020
- The Brazilian TP53 mutation (R337H) and sarcomas. 2020
- Coronarin D Induces Apoptotic Cell Death and Cell Cycle Arrest in Human Glioblastoma Cell Line. Biomolecules. 2019
- Genosensor made with a self-assembled monolayer matrix to detect MGMT gene methylation in head and neck cancer cell lines.. Talanta. 2019
- Mutation profiling of cancer drivers in Brazilian colorectal cancer. Acta Cytologica. 2019
- Matteucinol, isolated from Miconia chamissois, induces apoptosis in human glioblastoma lines via the intrinsic pathway and inhibits angiogenesis and tumor growth in vivo. Investigational New Drugs. 2019
- Semi-Synthetic Ingenol Derivative from Euphorbia tirucalli Inhibits Protein Kinase C Isotypes and Promotes Autophagy and S-phase Arrest on Glioma Cell Lines. Biomolecules. 2019
- Fractions Promote Cell Cycle Arrest and Inhibit Autophagic Flux in Human Cervical Cancer Cell Lines. Biomolecules. 2019
- Detection of the prostate cancer biomarker PCA3 with electrochemical and impedance-based biosensors.. ACS Applied Materials and Interfaces. 2019
- Mutational Profile of Driver Genes in Brazilian Melanomas.. Journal of Global Oncology. 2019
- Modified ingenol semi-synthetic derivatives from Euphorbia tirucalli induce cytotoxicity on a large panel of human cancer cell lines. Investigational New Drugs. 2019
- Squamous differentiation portends poor prognosis in low and intermediate-risk endometrioid endometrial cancer. 2019
- Identification and performance evaluation of housekeeping genes for microRNA expression normalization by reverse transcription-quantitative PCR using liquid-based cervical cytology samples.. Oncology Letters. 2019
- The role of single-nucleotide polymorphism (SNPs) in toxicity of induction chemotherapy based on cisplatin and paclitaxel in patients with advanced head and neck cancer.. Oral Oncology. 2019
- Hexane partition from Annona crassiflora Mart. promotes cytotoxity and apoptosis on human cervical cancer cell lines. Investigational New Drugs. 2019
- Lack of KBTBD4 Mutations in Molecularly Classified Brazilian Medulloblastomas. Journal of Neuropathology and Experimental Neurology. 2019
- Identification of Cell-Free Circulating MicroRNAs for the Detection of Early Breast Cancer and Molecular Subtyping.. Journal of Oncology. 2019
- Microbiota Profile and Impact of Fusobacterium nucleatum in Colorectal Cancer Patients of Barretos Cancer Hospital.. Frontiers in Oncology. 2019
- ID7 Isolated from Bauhinia variegata Stem Inhibits Tumor Progression and Metastatic Mechanisms of Triple Negative Breast Cancer in Vivo. Journal of Pharmacy and Pharmacology. 2019
- Current Status of Raf Kinase Inhibitor Protein (RKIP) in Lung Cancer: Behind RTK Signaling. Cells. 2019
- Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification.. Human Mutation. 2019
- Comparison of protocols for removal of melanin from genomic DNA to optimize PCR amplification of DNA purified from highly pigmented lesions.. Histology and Histopathology. 2019
- Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells. Investigational New Drugs. 2019
- Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma.. Leukemia. 2019
- Mutational profile of Brazilian lung adenocarcinoma unveils association of EGFR mutations with high Asian ancestry and independent prognostic role of KRAS mutations.. Acta Cytologica. 2019
- Zr-DFO-Cetuximab as a Molecular Imaging Agent to Identify Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma. . Cancer Biotherapy and Radiopharmaceuticals. 2019
- Establishment, molecular and biological characterization of HCB-514: a novel human cervical cancer cell line. Acta Cytologica. 2019
- EGF+61 A>G polymorphism is not associated with lung cancer risk in the Brazilian population.. Molecular Biology Reports. 2019
- Screen-printed interdigitated electrodes modified with nanostructured carbon nano-onion films for detecting the cancer biomarker CA19-9.. Biomaterials Advances. 2019
- WIN55,212-2 induces caspase-independent apoptosis on human glioblastoma cells by regulating HSP70, p53 and Cathepsin D.. Toxicology in Vitro. 2019
- Comparison of a New-generation Fecal Immunochemical Test (FIT) With Guaiac Fecal Occult Blood Test (gFOBT) in Detecting Colorectal Neoplasia Among Colonoscopy-referral Patients. Anticancer Research. 2019
- Genetic polymorphisms in genes of class switch recombination and multiple myeloma risk and survival: an IMMEnSE study.. Leukemia & Lymphoma. 2019
- PIK3CA mutations are frequent in esophageal squamous cell carcinoma associated with chagasic megaesophagus and are associated with a worse patient outcome.. Acta Cytologica. 2018
- Relationship between Fusobacterium nucleatum, inflammatory mediators and microRNAs in colorectal carcinogenesis.. World Journal of Gastroenterology. 2018
- The germline mutational landscape of BRCA1 and BRCA2 in Brazil. Acta Cytologica. 2018
- Crotoxin from Crotalus durissus terrificus venom: In vitro cytotoxic activity of a heterodimeric phospholipase A2 on human cancer-derived cell lines.. Toxicon. 2018
- Reactivation of latent HIV-1 in vitro using an ethanolic extract from Euphorbia umbellata (Euphorbiaceae) latex. 2018
- Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer.. Cell Reports. 2018
- Integrative Molecular Characterization of Malignant Pleural Mesothelioma.. Cancer Discovery. 2018
- Microfluidic-Based Genosensor to Detect Human Papillomavirus (HPV16) for Head and Neck Cancer.. ACS Applied Materials and Interfaces. 2018
- Screening and characterization of BRCA2 c.156_157insAlu in Brazil: Results from 1380 individuals from the South and Southeast.. Cancer Genetics. 2018
- A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-ß Superfamily.. Cell Systems. 2018
- Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.. Cancer Cell. 2018
- Comprehensive Characterization of Cancer Driver Genes and Mutations.. Cell. 2018
- Loss of Raf kinase inhibitor protein expression is associated with human papillomavirus 16 infection in anal tumors. Oncology Letters. 2018
- Reproducibility of the NanoString 22-gene molecular subgroup assay for improved prognostic prediction of medulloblastoma.. Neuropathology. 2018
- Brachyury oncogene is a prognostic factor in high-risk testicular germ cell tumors. Andrology. 2018
- Expression of tumor suppressors miR-195 and let-7a as potential biomarkers of invasive breast cancer.. Clinics. 2018
- Advantage of HSP110 (T17) marker inclusion for microsatellite instability (MSI) detection in colorectal cancer patients.. Oncotarget. 2018
- Construction and characterization of a new TRAIL soluble form, active at picomolar concentrations.. Oncotarget. 2018
- Presence of microsatellite instability in esophageal squamous cell carcinoma associated with chagasic megaesophagus.. Biomarkers in Medicine. 2018
- The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.. Cell Reports. 2018
- Detection of sputum cofilin-1 as indicator of malignancy. Brazilian Journal of Medical and Biological Research. 2018
- In vitro screening of cytotoxic activity of euphol from Euphorbia tirucalli on a large panel of human cancer-derived cell lines.. Experimental and Therapeutic Medicine. 2018
- WNT6 is a Novel Oncogenic Prognostic Biomarker in Human Glioblastoma. Theranostics. 2018
- A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.. Cancer Cell. 2018
- A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples.. Cell. 2018
- An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics.. Cell. 2018
- Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.. Cell. 2018
- Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas.. Cancer Cell. 2018
- Driver Fusions and Their Implications in the Development and Treatment of Human Cancers.. Cell Reports. 2018
- Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.. Cell Reports. 2018
- Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas.. Cell Reports. 2018
- Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types.. Cell Reports. 2018
- Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.. Cell Reports. 2018
- Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.. Cell. 2018
- Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers.. Cell Reports. 2018
- Oncogenic Signaling Pathways in The Cancer Genome Atlas.. Cell. 2018
- Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context.. Cell Reports. 2018
- Pathogenic Germline Variants in 10,389 Adult Cancers.. Cell. 2018
- Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics.. Cell. 2018
- Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types.. Cell Reports. 2018
- Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images.. Cell Reports. 2018
- Systematic Analysis of Splice-Site-Creating Mutations in Cancer.. Cell Reports. 2018
- The Immune Landscape of Cancer.. Immunity. 2018
- The relationship between esophageal cancer, chagasic megaesophagus and HPV: myths, tales or reality?. Histology and Histopathology. 2018
- The long non-coding RNA HOTAIR is transcriptionally activated by HOXA9 and is an independent prognostic marker in patients with malignant glioma. Oncotarget. 2018
- Evaluation of MLH1 variants of unclear significance.. Genes Chromosomes & Cancer. 2018
- Genetic variants of vascular endothelial growth factor predict risk and survival of gliomas. Tumor Biology. 2018
- Genomic and Functional Approaches to Understanding Cancer Aneuploidy.. Cancer Cell. 2018
- Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas.. Cell Systems. 2018
- Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines.. Cell Systems. 2018
- lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer.. Cancer Cell. 2018
- Absence of TERT promoter mutations in colorectal precursor lesions and cancer.. Genetics and Molecular Biology. 2018
- A simple architecture with self-assembled monolayers to build immunosensors for detecting the pancreatic cancer biomarker CA19-9. Analyst. 2018
- Bauhinia variegata candida Fraction Induces Tumor Cell Death by Activation of Caspase-3, RIP, and TNF-R1 and Inhibits Cell Migration and Invasion In Vitro.. Biomed Research International. 2018
- Loss of MTAP expression is a negative prognostic marker in Ewing sarcoma family of tumors.. Biomarkers in Medicine. 2018
- The Impact of MSI Phenotype by MLH1 Expression in Gastric Adenocarcinomas: Critical Analysis of the Brazilian Experience. Journal of Gastroenterology and Hepatology Research. 2018
- Monocarboxylate transporter 1 is a key player in glioma-endothelial cell crosstalk. Molecular Carcinogenesis. 2017
- Lack of microsatellite instability in gastrointestinal stromal tumors.. Oncology Letters. 2017
- Metabolic alterations underlying Bevacizumab therapy in glioblastoma cells. Oncotarget. 2017
- Immunosensor for Pancreatic Cancer Based on Electrospun Nanofibers Coated with Carbon Nanotubes or Gold Nanoparticles. ACS Omega. 2017
- Alginate hydrogel improves anti-angiogenic bevacizumab activity in cancer therapy. European Journal of Pharmaceutics and Biopharmaceutics. 2017
- Expression of tyrosine kinase receptor AXL is associated with worse outcome of metastatic renal cell carcinomas treated with sunitinib.. Urologic Oncology-Seminars and Original Investigations. 2017
- Identification of hereditary cancer in the general population: development and validation of a screening questionnaire for obtaining the family history of cancer.. Cancer Medicine. 2017
- A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America.. BMC Cancer. 2017
- Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.. Cancer Cell. 2017
- AKT can modulate the in vitro response of HNSCC cells to irreversible EGFR inhibitors.. Oncotarget. 2017
- Lung cancer samples preserved in liquid medium: One step beyond cytology. Diagnostic Cytopathology. 2017
- Brachyury, a driver of epithelial mesenchymal transition, as an independent prognostic factor in high-grade testicular germ cell tumors.. Journal of Clinical Oncology. 2017
- Detection of ALK fusion transcripts in FFPE lung cancer samples by NanoString technology.. BMC Pulmonary Medicine. 2017
- Molecular characterization of short-term primary cultures and comparison with corresponding tumor tissue of Brazilian glioblastoma patients. Translational Cancer Research. 2017
- Mutational profile of TP53 in esophageal squamous cell carcinoma associated with chagasic megaesophagus.. Diseases of the Esophagus. 2017
- Centrosome amplification in chondrosarcomas: A primary cell culture and cryopreserved tumor sample study. Oncology Letters. 2017
- Effects of the functional HOTAIR rs920778 and rs12826786 genetic variants in glioma susceptibility and patient prognosis. Journal of Neuro-Oncology. 2017
- HER Family Receptors are Important Theranostic Biomarkers for Cervical Cancer: Blocking Glucose Metabolism Enhances the Therapeutic Effect of HER Inhibitors. 2017
- Integrated genomic characterization of oesophageal carcinoma.. Nature. 2017
- Racial/Ethnic Disparities in Cervical Cancer Screening and Outcomes. Acta Cytologica. 2016
- Tapirira guianensis Aubl. Extracts Inhibit Proliferation and Migration of Oral Cancer Cells Lines. 2016
- Identification of miRSNPs associated with the risk of multiple myeloma. 2016
- MicroRNA profiling in human breast cancer cell lines exposed to the anti-neoplastic drug cediranib.. Oncology Reports. 2016
- Prevalence of BRCA1/BRCA2 mutations in a Brazilian population sample at-risk for hereditary breast cancer and characterization of its genetic ancestry.. Oncotarget. 2016
- Study of hTERT and Histone 3 Mutations in Medulloblastoma. 2016
- Targeting the hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells.. Oncogene. 2016
- Drivers of neuroendocrine prostate cancer. Translational Cancer Research. 2016
- Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation. Pharmacological Research. 2016
- Low mutation percentage of KRAS and BRAF genes in Brazilian anal tumors. 2016
- A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: Results from the IMMEnSE consortium and meta-analysis. 2016
- Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas. 2016
- Isolation, characterization and screening of the in vitro cytotoxic activity of a novel L-amino acid oxidase (LAAOcdt) from Crotalus durissus terrificus venom on human cancer cell lines. 2016
- Absence of microsatellite instability and BRAF (V600E) mutation in testicular germ cell tumors.. Andrology. 2016
- Oncogenetics service and the Brazilian public health system: the experience of a reference Cancer Hospital. 2016
- Copy Number Profiling of Brazilian Astrocytomas.. G3: Genes, Genomes, Genetics. 2016
- The metabolic microenvironment of melanomas: prognostic value of MCT1 and MCT4. 2016
- Anti-EGFR therapy: Strategies in head and neck squamous cell carcinoma. 2016
- Brachyury as a potential modulator of androgen receptor activity and a key player in therapy resistance in prostate cancer.. Oncotarget. 2016
- Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer.. Oncotarget. 2016
- Cytotoxicity of allitinib, an irreversible anti-EGFR agent, in a large panel of human cancer-derived cell lines: KRAS mutation status as a predictive biomarker. 2016
- The prognostic impact of TERT promoter mutations in glioblastomas is modified by the rs2853669 single nucleotide polymorphism. International Journal of Cancer. 2016
- Raf Kinase Inhibitor Protein Expression and Prognostic Value in Soft Tissue Sarcomas. Pathobiology. 2016
- SPINT2 Deregulation in Prostate Carcinoma. Journal of Histochemistry & Cytochemistry. 2016
- Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis. BMC Cancer. 2016
- Tumor Growth Suppression Induced by Biomimetic Silk Fibroin Hydrogels. 2016
- Lactate transporters and pH regulation: potential therapeutic targets in glioblastomas. 2015
- Molecular profiling, including TERT promoter mutations, of acral lentiginous melanomas. 2015
- Hotspot TERT promoter mutations are rare events in testicular germ cell tumors.. Tumor Biology. 2015
- TERT promoter mutations in soft tissue sarcomas.. International Journal of Biological Markers. 2015
- Transcriptional profiling of HOXA9-regulated genes in human glioblastoma cell models. Genomics Data. 2015
- Glucose Addiction in Cancer Therapy: Advances and Drawbacks.. Current Drug Metabolism. 2015
- Type 2 diabetes-related variants influence the risk of developing multiple myeloma: results from the IMMEnSE consortium.. Endocrine-Related Cancer. 2015
- KIAA1549: BRAF Gene Fusion and FGFR1 Hotspot Mutations Are Prognostic Factors in Pilocytic Astrocytomas.. Journal of Neuropathology and Experimental Neurology. 2015
- Expression of Methylthioadenosine Phosphorylase (MTAP) in Pilocytic Astrocytomas.. Pathobiology. 2015
- The embryonic Brachyury transcription factor is a novel biomarker of GIST aggressiveness and poor survival. 2015
- Tissue hyaluronan expression, as reflected in the sputum of lung cancer patients, is an indicator of malignancy. 2015
- A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide. 2015
- Impact of TGF-ß1 -509C/T and 869T/C polymorphisms on glioma risk and patient prognosis. Tumor Biology. 2015
- Absence of Microsatellite Instability In Soft Tissue Sarcomas.. Pathobiology. 2015
- AXL as a modulator of sunitinib response in glioblastoma cell lines. 2015
- Ancestry of the Brazilian TP53 c.1010G>A (p.Arg337His, R337H) Founder Mutation: Clues from Haplotyping of Short Tandem Repeats on Chromosome 17p. 2015
- In vitro and in vivo studies of temozolomide loading in zeolite structures as drug delivery systems for glioblastoma. Nanoscale. 2015
- Molecular Profiling of a Rare Rosette-Forming Glioneuronal Tumor Arising in the Spinal Cord. 2015
- Silencing of WNK2 is associated with upregulation of MMP2 and JNK in gliomas. Oncotarget. 2015
- Silencing of the tumor suppressor gene WNK2 is associated with upregulation of MMP2 and JNK in gliomas. 2014
- KRAS and BRAF mutations and MSI status in precursor lesions of colorectal cancer detected by colonoscopy.. Oncology Reports. 2014
- Low frequency of TERT promoter mutations in gastrointestinal stromal tumors (GISTs).. European Journal of Human Genetics. 2014
- The Brazilian Founder Mutation TP53 p.R337H is Uncommon in Portuguese Women Diagnosed with Breast Cancer.. Breast Journal. 2014
- Risk of multiple myeloma is associated with polymorphisms within telomerase genes and telomere length.. International Journal of Cancer. 2014
- T-box Transcription Factor Brachyury Is Associated with Prostate Cancer Progression and Aggressiveness. Clinical Cancer Research. 2014
- Genetic variants and multiple myeloma risk: IMMEnSE validation of the best reported associations--an extensive replication of the associations from the candidate gene era.. Cancer Epidemiology Biomarkers & Prevention. 2014
- Serrated pathway in colorectal carcinogenesis.. World Journal of Gastroenterology. 2014
- Characterization of monocarboxylate transporters (MCTs) expression in soft tissue sarcomas: distinct prognostic impact of MCT1 sub-cellular localization. Journal of Translational Medicine. 2014
- Immunoglobulin genes implicated in glioma risk. Oncoimmunology. 2014
- The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma.. Acta Neuropathologica Communications. 2014
- Biomarkers and novel therapeutic targets in gastrointestinal stromal tumors (GISTs).. Recent Patents on Anti-Cancer Drug Discovery. 2013
- In Vitro and In Vivo Analysis of RTK Inhibitor Efficacy and Identification of Its Novel Targets in Glioblastomas. Translational Oncology. 2013
- Loci identified through genome-wide association studies and lung cancer risk: is there anything more?. São Paulo Medical Journal. 2013
- RKIP Inhibition in Cervical Cancer Is Associated with Higher Tumor Aggressive Behavior and Resistance to Cisplatin Therapy 2013
- Low RKIP expression associates with poor prognosis in bladder cancer patients. Virchows Archiv. 2013
- A Hospital Based Cohort Study of Colorectal Cancer Cases Treated at Braga Hospital, Northern Portugal. Journal of Gastrointestinal & Digestive System. 2013
- Absence of RKIP expression is an independent prognostic biomarker for gastric cancer patients. Oncology Reports. 2013
- Analysis of a synchronous gliosarcoma and meningioma with long survival: A case report and review of the literature. Surgical Neurology International. 2013
- Early Pseudoprogression following Chemoradiotherapy in Glioblastoma Patients: The Value of RANO Evaluation. Journal of Oncology. 2013
- Emissions generated by sugarcane burning promote genotoxicity in rural workers: a case study in Barretos, Brazil. Environmental Health. 2013
- Erratum: Polymorphisms in xenobiotic transporters ABCB1, ABCG2, ABCC2, ABCC1, ABCC3 and multiple myeloma risk: A case - Control study in the context of the International Multiple Myeloma rESEarch (IMMEnSE) consortium (Leukemia (2012) 26 (1419-1422) DOI: 10.1038/leu.2011.352). Leukemia. 2013
- Frequency of TERT promoter mutations in human cancers. Nature Communications. 2013
- Histone H3.3 Mutations Drive Pediatric Glioblastoma through Upregulation of MYCN. Cancer Discovery. 2013
- Loss of WNK2 expression by promoter gene methylation occurs in adult gliomas and triggers Rac1-mediated tumour cell invasiveness. Human Molecular Genetics. 2013
- Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets. Neuro-Oncology. 2013
- Novel Oncogenic PDGFRA Mutations in Pediatric High-Grade Gliomas. Cancer Research. 2013
- Optimization of a pentaplex panel for MSI analysis without control DNA in a Brazilian population: correlation with ancestry markers. European Journal of Human Genetics. 2013
- Planning cancer control in Latin America and the Caribbean. Lancet Oncology. 2013
- Polymorphisms in regulators of xenobiotic transport and metabolism genes PXR and CAR do not affect multiple myeloma risk: a case-control study in the context of the IMMEnSE consortium. Journal of Human Genetics. 2013
- The impact of polymorphic variations in the 5p15, 6p12, 6p21 and 15q25 Loci on the risk and prognosis of portuguese patients with non-small cell lung cancer 2013
- The role of microRNAs in medulloblastoma. Pediatric Hematology and Oncology. 2013
- Zeolite Structures Loading with an Anticancer Compound As Drug Delivery Systems. Journal of Physical Chemistry C. 2012
- Involvement of signaling molecules in the prediction of response to imatinib treatment in metastatic GIST patients. Journal of Surgical Research. 2012
- Comprehensive investigation of genetic variation in the 8q24 region and multiple myeloma risk in the IMMEnSE consortium. British Journal of Haematology. 2012
- Downregulation of RKIP Is Associated with Poor Outcome and Malignant Progression in Gliomas 2012
- Angiogenic potential of gellan-gum-based hydrogels for application in nucleus pulposus regeneration: in vivo study. 2012
- Association between EGF +61 genetic polymorphisms and non-small cell lung cancer increased risk in a Portuguese population: A case-control study. Tumor Biology. 2012
- Co-expression of monocarboxylate transporter 1 (MCT1) and its chaperone (CD147) is associated with low survival in patients with gastrointestinal stromal tumors (GISTs). Journal of Bioenergetics and Biomembranes. 2012
- Decoy activity through microRNAs: the therapeutic implications.. Expert Opin Biol Ther. 2012
- Detection of the Epstein-Barr virus in blood and bone marrow mononuclear cells of patients with aggressive B-cell non-Hodgkin's lymphoma is not associated with prognosis. Oncology Letters. 2012
- Genetics and molecular epidemiology of multiple myeloma: the rationale for the IMMEnSE consortium (review).. International Journal of Oncology. 2012
- Impact of polymorphic variation at 7p15.3, 3p22.1 and 2p23.3 loci on risk of multiple myeloma. British Journal of Haematology. 2012
- Insights into angiogenesis in non-small cell lung cancer: molecular mechanisms, polymorphic genes, and targeted therapies.. Recent Patents on Anti-Cancer Drug Discovery. 2012
- Polymorphisms in xenobiotic transporters ABCB1, ABCG2, ABCC2, ABCC1, ABCC3 and multiple myeloma risk: A case-control study in the context of the International Multiple Myeloma rESEarch (IMMEnSE) consortium. Leukemia. 2012
- Strand-specific miR-28-5p and miR-28-3p have distinct effects in colorectal cancer cells. Gastroenterology. 2012
- Encapsulation of a-cyano-4-hydroxycinnamic acid into a NaY zeolite. Carbohydrate Polymers. 2011
- Loss of RKIP expression during the carcinogenic evolution of endometrial cancer. Journal of Clinical Pathology. 2011
- Association between EGF +61A/G polymorphism and gastric cancer in Caucasians.. World Journal of Gastroenterology. 2011
- BRCA1, microRNAs and cancer predisposition: challenging the dogma.. Cell Cycle. 2011
- Impact of EGFR genetic variants on glioma risk and patient outcome. Cancer Epidemiology Biomarkers & Prevention. 2011
- Is the gastrointestinal stromal tumor arising in the rectovaginal septum an extragastrointestinal entity? A time for reflection. International Journal of Colorectal Disease. 2011
- Lymphangiogenic VEGF-C and VEGFR-3 expression in genetically characterised gastrointestinal stromal tumours. Histology and Histopathology. 2011
- Methacrylated gellan gum hydrogels for application in nucleus pulposus regeneration: In vitro and in vivo studies. 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials. 2011
- MicroRNA history: Discovery, recent applications, and next frontiers. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 2011
- Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation 2011
- Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer.. BMC Cancer. 2011
- Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma. Neuro-Oncology. 2011
- Role of endoglin and VEGF family expression in colorectal cancer prognosis and anti-angiogenic therapies. World Journal of Clinical Oncology. 2011
- The selective COX-2 inhibitor Etoricoxib reduces acute inflammatory markers in a model of neurogenic laryngitis but loses its efficacy with prolonged treatment. Inflammation Research. 2010
- Prognostic value of MGMT promoter methylation in glioblastoma patients treated with temozolomide-based chemoradiation: A Portuguese multicentre study. Oncology Reports. 2010
- A distinct spectrum of copy number aberrations in pediatric high-grade gliomas. Clinical Cancer Research. 2010
- Expression of Monocarboxylate Transporters 1, 2, and 4 in Human Tumours and Their Association with CD147 and CD44. Biomed Research International. 2010
- MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature. Cancer Research. 2010
- MYC-microRNA-9-metastasis connection in breast cancer. Cell Research. 2010
- MicroRNAs and metastases: The neuroblastoma link. Cancer Biology & Therapy. 2010
- Reversing HOXA9 oncogene activation by PI3K inhibition: Epigenetic mechanism and prognostic significance in human glioblastoma. Cancer Research. 2010
- A Canadian paediatric brain tumour consortium (CPBTC) phase II molecularly targeted study of imatinib in recurrent and refractory paediatric central nervous system tumours. Eur J Cancer. 2009
- Loss of RKIP expression is associated with poor survival in GISTs. Virchows Archiv. 2009
- Low frequency of MAP kinase pathway alterations in KIT and PDGFRA wild-type GISTs. Histopathology. 2009
- Molecular characterization of EGFR, PDGFRA and VEGFR2 in cervical adenosquamous carcinoma. BMC Cancer. 2009
- Analysis of microsatellite instability in medulloblastoma. Neuro-Oncology. 2009
- EGFRvIII deletion mutations in pediatric high-grade glioma and response to targeted therapy in pediatric glioma cell lines. Clinical Cancer Research. 2009
- Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas. British Journal of Cancer. 2009
- Liquid-based cytology in DNA-based molecular research viability and potential application. Analytical and Quantitative Cytology and Histology. 2009
- Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development 2009
- TP53 germline mutations in Portugal and genetic modifiers of age at cancer onset.. Fam Cancer. 2009
- KIT activation in uterine cervix adenosquamous carcinomas by KIT / SCF autocrine/paracrine stimulation loops. Gynecologic Oncology. 2008
- A New Model of Laryngitis: Neuropeptide, Cyclooxygenase, and Cytokine Profile. Laryngoscope. 2008
- Analysis of EGFR overexpression, EGFR gene amplification and the EGFRvIII mutation in Portuguese high-grade gliomas. Anticancer Research. 2008
- Molecular alterations of KIT and PDGFRA in GISTs: Evaluation of a Portuguese series. Journal of Clinical Pathology. 2008
- TP53 codon 72 polymorphism in susceptibility, overall survival, and adjuvant therapy response of gliomas. Cancer Genetics and Cytogenetics. 2008
- Association between functional EGF+61 polymorphism and glioma risk. Clinical Cancer Research. 2007
- DNA copy number profiles of gastric cancer precursor lesions. BMC Genomics. 2007
- Molecular alterations of KIT oncogene in gliomas. Cellular Oncology. 2007
- Molecular analysis of c-Kit and PDGFRA in GISTs diagnosed by EUS. American Journal of Clinical Pathology. 2007
- Mutations in gastrointestinal stromal tumors diagnosed by endoscopic ultrasound-guided fine needle aspiration. Minerva Medica. 2007
- EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. Journal of Pathology. 2006
- Mixed gastric carcinomas show similar chromosomal aberrations in both their diffuse and glandular components. Cellular Oncology. 2006
- U-2940, a human B-cell line derived from a diffuse large cell lymphoma sequential to Hodgkin lymphoma.. International Journal of Cancer. 2006
- Differential Prox-1 and CD 31 expression in mucousae, cutaneous and soft tissue vascular lesions and tumors. Pathology Research and Practice. 2005
- Molecular characterization of PDGFR-a/PDGF-A and c-KIT/SCF in gliosarcomas. Cellular Oncology. 2005
- Mutation analysis of B-RAF gene in human gliomas. Acta Neuropathologica. 2005
- Overexpression of platelet-derived growth factor receptor alpha in breast cancer is associated with tumour progression.. Breast Cancer Research. 2005
- Genetic alterations of adult and paediatric astrocytic tumours. Revista de Neurologia. 2004
- Erratum: Mutation analysis of hBUB1, hBUBR1 and hBUB3 genes in glioblastomas (Acta Neuropathologica (2001) vol. 101 (297-304)). Acta Neuropathologica. 2001
- Genetic evidence of the neoplastic nature of gemistocytes in astrocytomas. Acta Neuropathologica. 2001
- Mutation analysis of hBUB1, hBUBR1 and hBUB3 genes in glioblastomas. Acta Neuropathologica. 2001
- Second primary glioblastoma. Journal of Neuropathology and Experimental Neurology. 2001
- Genetic Profile of Gliosarcomas. American Journal of Pathology. 2000
- Extended structural variation of a pentanucleotide repeat in the GSTP1 gene: characterisation in a normal population and in thyroid and gastric tumours.. European Journal of Human Genetics. 2000
- Loss of heterozygosity on chromosome 10 is more extensive in primary (de novo) than in secondary glioblastomas. Laboratory Investigation. 2000
- Acquisition of the glioblastoma phenotype during astrocytoma progression is associated with loss of heterozygosity on 10q25-qter.. American Journal of Pathology. 1999
- Identification in human brain tumors of DNA sequences specific for SV40 large T antigen. Brain Pathology. 1999
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artigo de conferência
- Omics profile of two immortalized Brazilian glioblastoma cell cultures. 2018
- AKT can modulate the in vitro response of HNSCC cell to irreversible EGFR inhibitors 2017
- Protein Kinase WNK2 has a Tumour Suppressor Role in Gliomas 2012
- Analysis of raf kinase inhibitor protein (RKIP) expression as a prognostic marker for glioblastomas 2010
- Analysis of MAP kinase signalling pathway in KIT & PDGFRA wild-type GISTs 2008
-
capítulo de livro
- Implications of RKIP protein in cancer prognosis and therapy response: A literature update 2020
- Classificação Molecular do Câncer de Mama 2018
- The Role of Angiogenesis in Non-small Cell Lung Cancer Tumor Behavior 2017
- Bevacizumab for Glioblastoma Treatment: Reviewing Biological and Clinical Hypothesis for its Success and Failures 2016
- Brain Tumor Metabolism — Unraveling Its Role in Finding New Therapeutic Targets 2015
- Pilocytic Astrocytoma: Anatomic, Pathological and Molecular Aspects 2013
- Role of Genetic Polymorphisms in the Angiogenesis Pathway and Non-small-Cell Lung Cancer Tumor Behavior: Implications in Risk Assessment and Clinical Outcome 2013
- BRAF in glioblastomas: Clinical implications 2012
- Pediatric High-Grade Glioma: Role of Microsatellite Instability 2012
- The Role of Immunohistochemistry in the Diagnostic and Prognostic of Glioblastoma Patients 2012
- Genetic Instability in Paediatric and Adult Brain Tumours 2011
- Malignant Gliomas: Role of Platelet-Derived Growth Factor Receptor A (PDGFRA) 2011
- Gliosarcoma 2000
-
documento
- Uncovering a novel modulator of cancer metabolism and BRAF inhibitor sensitivity in melanoma 2025
- Treatment with 3-bromopyruvate boosts the effect of chemotherapy in acute myeloid leukemia 2025
- High levels of the immune checkpoint CD276 (B7-H3) in malignant cells and macrophages suggest its potential target for glioblastoma immunotherapy 2024
- Molecular Profile of Driver Genes in Lung Adenocarcinomas of Brazilian Patients Who Have Never Smoked: Implications for Targeted Therapies. 2024
- Targeting glucose metabolism in acute myeloid leukemia (AML) chemoresistance 2024
- Beyond the MAPK Pathway: Unravelling the Importance of RKIP in Lung Adenocarcinoma 2023
- Alta frequência de meduloblastomas WNT CTNNB1 tipo selvagem sugere maior proporção de casos hereditários na população latino-ibérica 2023
- SPINT2: a potential biomarker for melanoma patients 2021
- Untangling the role of RKIP in NSCLC aggressiveness: an in vitro /in vivo and in silico analysis 2021
- A proteína RKIP como um novo preditor de resposta a terapias anti-EGFR em cancro do pulmão 2021
- Compreender a regulação e sinalização da RKIP no cancro do colo do útero: RKIP/HER loop 2021
- Fator de transcrição embrionário T-boxBrachyury como biomarcador de resposta e alvo terapêutico em cancro do pulmão 2021
- Exploring the predictive andtherapeutic value of the embryonic T-box transcription factor Brachyury in lung cancer 2021
- SPINT2 downregulation in Melanoma influences EMT 2021
- Embryonic T-box transcription factor Brachyury as a predictive biomarker andtherapeutic target in lung cancer 2021
- SPINT2 role and therapeutic influence in Melanoma 2020
- Integrative analysis of mRNA and miRNA pro¿les identifies miR-193 and miR-210 as potential regulatory biomarkers in di¿erent molecular subtypes of breast cancer 2020
- Frequency of HPV detection in chagasic megaesophagus associated or not with esophageal squamous cell carcinoma 2020
- HPV detection within a case series of chagasic megaesophagus associated or not with esophageal squamous cell carcinoma 2020
- Potential biomarkers of ductal carcinoma in situ progression 2020
- Therapeutic relevance of SPINT2 in Melanoma. 2019
- Modulation of macrophage-cancer cell interaction by the hypoxic colon cancer microenvironment. 2019
- RKIP protein as a potential prognostic, aggressiveness and therapy response biomarker in HNSCC 2019
- Squamous differentiation portends poor prognosis in low and intermediate-risk endometrioid endometrial cancer 2019
- Hypoxia alters colon cancer macrophage-cancer cell interactions. 2019
- Colon cancer hypoxic ecosystem alters macrophage-cancer cell interactions. 2019
- The hypoxia impact in the macrophage-driven cancer cell invasive phenotype 2018
- PO-473 Wnt6 expression in glioblastoma: mechanistic, functional and clinical implications 2018
- Study of functional role and therapeutic influence of the tumor suppressor gene SPINT2 in Melanoma. 2018
- STUDY OF TERT AND MECHANISTICALLY RELATED MOLECULES INMEDULLOBLASTOMAS 2014
- Abstract C118: TERT promoter mutations in human gliomas. 2013
- Association of ESR1 Polymorphisms with Tamoxifen Response in Women with Estrogen Receptor-Positive Breast Cancer 2013
- A Distinct Spectrum Of Copy Number Aberrations In Formalin-Fixed, Paraffin-Embedded Paediatric High Grade Glioma. 2010
- 95 Associations between functional EGFR polymorphisms and glioma risk 2010
- Microsatellite instability in paediatric high grade glioma and medulloblastoma 2009
- Microsatellite instability: A new type of genetic instability in medulloblastomas? 2009
- Absence of KIT gene mutations and amplification in medulloblastomas. 2008
- Absence of KIT gene mutations and amplification in medulloblastomas 2008
- Study of molecular mechanisms underlying oncogenic c-Kit overexpression in gliomas. 2006
- No Association between EGFR Promoter Gene Polymorphisms and Gliomas Risk. 2006
- Biological and molecular characterization of HCB-289: a Brazilian head and neck cancer stem-like cell line
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