publicações selecionadas
-
artigo académico
- Glucose Metabolism as a Potential Therapeutic Target in Cytarabine-Resistant Acute Myeloid Leukemia. Pharmaceutics. 2024
- A transcriptomic profiling reveals novel roles of Cadherin-3 in metabolic programming of glioblastoma 2024
- A transcriptomic profiling reveals novel roles of Cadherin-3 in metabolic programming of glioblastoma - in final phase of preparation 2024
- Synthesis and Biological Evaluation of Novel Chromeno[2,3-d]Pyrimidinones as Agents for Triple Negative Breast Cancer Treatment. European Journal of Medicinal Chemistry (IF 7.08, Q1 Chemistry, Organic). 2023
- Non-Alcoholic Fatty Liver Disease-Related Hepatocellular Carcinoma: Immunohistochemical Assessment of Markers of Cancer Cell Metabolism. Pathobiology. 2022
- Modulating chitosan-PLGA nanoparticle properties to design a co-delivery platform for glioblastoma therapy intended for nose-to-brain route. Drug Delivery and Translational Research. 2020
- In vitro Evaluation of ASCs and HUVECs Co-cultures in 3D Biodegradable Hydrogels on Neurite Outgrowth and Vascular Organization. Frontiers in Cell and Developmental Biology. 2020
- IL-17A and IL-17F orchestrate macrophages to promote lung cancer. Cellular Oncology. 2020
- Lactate Beyond a Waste Metabolite: Metabolic Affairs and Signaling in Malignancy. Frontiers in Oncology. 2020
- A novel strategy for glioblastoma treatment combining alpha-cyano-4-hydroxycinnamic acid with cetuximab using nanotechnology-based delivery systems. Drug Delivery and Translational Research. 2020
- Gene Disruption Using Zinc Finger Nuclease Technology. Methods in Molecular Biology. 2014
-
artigo de revista
- Targeting Lysosomes in Colorectal Cancer: Exploring the Anticancer Activity of a New Benzo[a]phenoxazine Derivative. International Journal of Molecular Sciences. 2022
- MCT1 Is a New Prognostic Biomarker and Its Therapeutic Inhibition Boosts Response to Temozolomide in Human Glioblastoma. Cancers. 2021
- Cancer Cells’ Metabolism Dynamics in Renal Cell Carcinoma Patients’ Outcome: Influence of GLUT-1-Related hsa-miR-144 and hsa-miR-186. Cancers. 2021
- Surface functionalization of zeolite-based drug delivery systems enhances their antitumoral activity in vivo. Journal of Nanoparticle Research. 2021
- Immunity, hypoxia, and metabolism–the ménage à trois of cancer: Implications for immunotherapy. Physiological Reviews. 2020
- Fucoidan from Fucus vesiculosus inhibits new blood vessel formation and breast tumor growth in vivo. Carbohydrate Polymers. 2019
- Rational Identification of a Colorectal Cancer Targeting Peptide through Phage Display. Acta Cytologica. 2019
- Bioenergetic modulators hamper cancer cell viability and enhance response to chemotherapy. Journal of Cellular and Molecular Medicine. 2018
- Metabolic alterations underlying Bevacizumab therapy in glioblastoma cells. Oncotarget. 2017
- Impact of mesenchymal stem cells' secretome on glioblastoma pathophysiology. Journal of Translational Medicine. 2017
- Value of pH regulators in the diagnosis, prognosis and treatment of cancer. Seminars in Cancer Biology. 2017
- GLUT1 expression in pediatric adrenocortical tumors: A promising candidate to predict clinical behavior. Oncotarget. 2017
- HER Family Receptors are Important Theranostic Biomarkers for Cervical Cancer: Blocking Glucose Metabolism Enhances the Therapeutic Effect of HER Inhibitors. Theranostics. 2017
- The expression of monocarboxylate transporters in thyroid carcinoma can be associated with the morphological features of BRAF V600E mutation. Endocrine. 2016
- Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas. Oncotarget. 2016
- Prognostic significance of monocarboxylate transporter expression in oral cavity tumors. Cell Cycle. 2016
- Knock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its pro-tumour action via extracellular matrix metalloproteases (MMPs) induction. Oncotarget. 2015
- Glucose Addiction in Cancer Therapy: Advances and Drawbacks.. Current Drug Metabolism. 2015
- Targeting lactate transport suppresses in vivo breast tumour growth. Oncotarget. 2015
- Disruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 status. Oncotarget. 2015
- Metabolic reprogramming: A new relevant pathway in adult adrenocortical tumors. Oncotarget. 2015
- Automated image analysis of lung branching morphogenesis from microscopic images of fetal rat explants.. Computational and Mathematical Methods in Medicine. 2014
- RKIP Inhibition in Cervical Cancer Is Associated with Higher Tumor Aggressive Behavior and Resistance to Cisplatin Therapy. Antibiotics. 2013
- The Monocarboxylate Transporter Inhibitor a-Cyano-4-Hydroxycinnamic Acid Disrupts Rat Lung Branching. Cellular Physiology and Biochemistry. 2013
- Downregulation of RKIP Is Associated with Poor Outcome and Malignant Progression in Gliomas. Antibiotics. 2012
-
capítulo de livro
- Lactate and lactate transporters as key players in the maintenance of the Warburg effect 2020
- New horizons on pH regulators as cancer biomarkers and targets for pharmacological intervention 2020
- Targeting Metabolic Reprogramming as an Anti- Cancer Strategy: Aiming at Monocarboxylate Transporters 2015
-
documento
- Unveiling the impact of the oncogenic molecule Cadherin-3 in the metabolism of human glioblastoma 2023
- Unveiling the impact of the oncogenic molecule Cadherin-3 in themetabolism of human glioblastoma 2023
- Role of RKIP protein in the modulation of lung cancer cell metabolism 2021
- 3-bromopyruvate boosts the effect of chemotherapy in acute myeloid leukemia by reducing cell antioxidant defense 2020
- Non-toxic concentrations of 3-bromopyruvate sensitize acute leukemia cells to chemotherapy by inducing oxidative stress 2020
- Disruption of cancer cell metabolism using targeted-drug delivery systems 2019
- Role of RKIP protein in the modulation of cancer cells metabolism in solid tumors 2019
- Disruption of cancer cell metabolism using targeted drug delivery systems. 2019
- Unveiling the role of diet microbiome-derived short chain fatty acids in colorectal cancer metabolism. 2019
- In vitro and in vivo efficacy evaluation of drug delivery systems based on zeolites 2019
- 3-Bromopyruvate pre-treatment sensitizes MOLM13 and KG-1 cell lines to chemotherapy. 2019
- 3-Bromopyruvate pre-treatment sensitizes MOLM13 and KG-1 cell lines to chemotherapy 2019
- The role of acetate in oncogene signalling activation and metabolism in colorectal cancer. 2018
- Uncovering the role of acetate in the crosstalk between monocarboxylate transporters and oncogene signaling pathways in colorectal cancer 2018
- Targeting cancer cell metabolism using targeted-drug delivery systems 2018
- Elucidating the impact of IL-17A/F in lung cancer 2018
- Fucoidan impairs angiogenesis and tumor growth in vivo 2018
- Fucoidan inhibits new blood vessels formation in a tumor microenvironment 2018
- New chromene-based drug candidates for cancer treatment 2017
- Understanding the cellular metabolic reprogramming associated with bevacizumab therapy in glioblastoma 2017
- Blocking glucose metabolism enhances the effect of HER inhibitors in cervical cancer therapy 2016
- Targeting glycolysis in acute myeloid leukemia: therapeutic applications. 2016
- HER receptors are important theranostic biomarkers on cervical cancer: blocking glucose metabolism enhances the therapeutic effect of HER inhibitors 2016
- HER receptors are important theranostic biomarkers on cervical cancer: blocking glucose metabolism enhances the therapeutic effect of HER inhibitors. 2016
- Targeting glycolysis in acute myeloid leukemia: therapeutic applications 2016
- Targeting lactate transport suppresses in vivo breast tumor growth 2015
- The Warburg effect:¿a new relevant road in the biology of adrenocortical tumors in adults 2015
- Increased expression of monocarcboxylate transporters 1 and 4 and carbonic anhydrase IX in pancreatic ductal adenocarcinomas 2015
- The Warburg effect: a new relevant road in the biology of adrenocortical tumors in adults 2015
- The role of Monocarboxylate transporters in lung cancer 2011
- Shifting KRAS hotspot mutations inhibition paradigm in colorectal cancer
-
poster de conferência
- 3-bromopyruvate boosts the effect of chemotherapy in acute myeloid leukemia by reducing cell antioxidant defense 2020
- Non-toxic concentrations of 3-bromopyruvate sensitize acute leukemia cells to chemotherapy by inducing oxidative stress 2020
- 3-Bromopyruvate pre-treatment sensitizes MOLM13 and KG-1 cell lines to chemotherapy 2019
-
teses