publicações selecionadas
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artigo académico
- Mitochondrial Dysfunction and Decreased Cytochrome c in Cell and Animal Models of Machado-Joseph Disease. Cells. 2023
- Transition from Animal-Based to Human Induced Pluripotent Stem Cells (iPSCs)-Based Models of Neurodevelopmental Disorders: Opportunities and Challenges. Cells. 2023
- Cerebellar neuronal dysfunction accompanies early motor symptoms in spinocerebellar ataxia type 3. Disease Models & Mechanisms. 2022
- Modifier pathways in polyglutamine (PolyQ) diseases: from genetic screens to drug targets (IF: 8.0). Cellular and Molecular Life Sciences. 2022
- Case Report: A Novel GNB1 Mutation Causes Global Developmental Delay With Intellectual Disability and Behavioral Disorders. Frontiers in Neurology. 2021
- Impact of rapeseed pomace extract on markers of oxidative stress and DNA damage in human SH-SY5Y cells. Journal of Food Biochemistry. 2020
- Polyglutamine spinocerebellar ataxias: emerging therapeutic targets. Expert Opinion on Therapeutic Targets. 2020
- In Vivo Molecular Signatures of Cerebellar Pathology in Spinocerebellar Ataxia Type 3. Movement Disorders. 2020
- Loss of egli-1, the Caenorhabditis elegans Orthologue of a Downstream Target of SMN, Leads to Abnormalities in Sensorimotor Integration. Molecular Neurobiology. 2020
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artigo de conferência
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artigo de revista
- Learning the Biochemical Basis of Axonal Guidance: Using Caenorhabditis elegans as a Model. Biomedicines. 2023
- Microglial Depletion Has No Impact on Disease Progression in a Mouse Model of Machado-Joseph Disease. Cells. 2022
- Neurotherapeutic effect of Hyptis spp. leaf extracts in Caenorhabditis elegans models of tauopathy and polyglutamine disease: Role of the glutathione redox cycle. Free Radical Biology and Medicine. 2021
- From Pathogenesis to Novel Therapeutics for Spinocerebellar Ataxia Type 3: Evading Potholes on the Way to Translation. Neurotherapeutics. 2019
- Preclinical Evidence Supporting Early Initiation of Citalopram Treatment in Machado-Joseph Disease. Molecular Neurobiology. 2019
- Citalopram Reduces Aggregation of ATXN3 in a YAC Transgenic Mouse Model of Machado-Joseph Disease. Molecular Neurobiology. 2018
- Neuroprotective Effects of Creatine in the CMVMJD135 Mouse Model of Spinocerebellar Ataxia Type 3. Movement Disorders. 2018
- Altered striatal endocannabinoid signaling in a transgenic mouse model of spinocerebellar ataxia type-3. Antibiotics. 2017
- Novel candidate blood-based transcriptional biomarkers of machado-joseph disease. Movement Disorders. 2015
- Using C-elegans to Decipher the Cellular and Molecular Mechanisms Underlying Neurodevelopmental Disorders. Molecular Neurobiology. 2013
- Absence of Ataxin-3 Leads to Enhanced Stress Response in C. elegans. Antibiotics. 2011
- Absence of ataxin-3 leads to cytoskeletal disorganization and increased cell death. Biochimica Et Biophysica Acta-Molecular Cell Research. 2010
- Ataxin-3 Plays a Role in Mouse Myogenic Differentiation through Regulation of Integrin Subunit Levels. Antibiotics. 2010
- ATX-3, CDC-48 and UBXN-5: A new trimolecular complex in Caenorhabditis elegans. Biochemical and Biophysical Research Communications. 2009
- Functional genomics and biochemical characterization of the C-elegans orthologue of the Machado-Joseph disease protein ataxin-3. Faseb Journal. 2007
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capítulo de livro
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documento
- Therapeutical potential of tauroursodeoxycholic acid in stress-related brain pathologies 2023
- Assessing the HPA-axis mediated stress responses in a mouse model of SCA3 2023
- The study of depression and cognitive comorbidities in a mouse model of spinocerebellar ataxia type 3 2022
- NLX-112 improved the motor coordination and balance in a Mouse Experimental Model of Machado-Joseph Disease 2021
- Serotonergic Signalling Activation as a Therapeutic Approach for Neurodegenerative Disorders 2021
- Neuroprotective effects of Hemerocallis citrina extracts in Caenorhabditis elegans models of neurodegenerative diseases 2021
- New chromene derivatives: unravelling the molecular mechanisms for breast cancer treatment 2019
- Exploitation of novel chromene derivatives for breast cancer treatment 2019
- Exploitation of novel chromene derivatives for breast cancer treatment. 2019
- Regulation of neuronal mRNA splicing and Tau isoform ratio by ATXN3 through deubiquitylation of splicing factors 2019
- New chromene derivatives: Unraveling the molecular mechanisms for breast cancer therapy 2019
- New chromene derivatives: Unraveling the molecular mechanisms for breast cancer therapy. 2019
- In vitro and in vivo evaluation of new chromene derivatives as potent anticancer agents 2019
- In vitro and in vivo evaluation of new chromene derivatives as potent anticancer agents. 2019
- Anti-aging genetic manipulation in C. elegans impact differentially in Machado-Joseph disease 2019
- Neuroprotective and antioxidant effects of Maranta arundinacea and Porophyllum ruderale in Caenorhabditis elegans 2019
- Targeting of the Serotonin (1A) Receptor Suppresses Mutant Ataxin-3 Pathogenesis in C. elegans 2019
- Antioxidant and neuroprotective effects of Hyptis suaveolens,Hyptis pectinata and Hyptis marrubioides in Caenorhabditiselegans. Chinese Medicine. 2018
- Absence of MeCP2 increases postnatal dentate gyrus cell proliferation in a mouse model of Rett syndrome. 2008