publicações selecionadas
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artigo académico
- Genetic Ablation of Inositol 1,4,5-Trisphosphate Receptor Type 2 (IP3R2) Fails to Modify Disease Progression in a Mouse Model of Spinocerebellar Ataxia Type 3. International Journal of Molecular Sciences. 2023
- Intrathecal Injection of the Secretome from ALS Motor Neurons Regulated for miR-124 Expression Prevents Disease Outcomes in SOD1-G93A Mice. Biomedicine. 2022
- Profiling Microglia in a Mouse Model of Machado-Joseph Disease. Biomedicine. 2022
- Microglial Depletion Has No Impact on Disease Progression in a Mouse Model of Machado-Joseph Disease. Cells. 2022
- Preclinical Assessment of Mesenchymal-Stem-Cell-Based Therapies in Spinocerebellar Ataxia Type 3. Biomedicine. 2021
- Unilateral Intrastriatal 6-Hydroxydopamine Lesion in Mice: A Closer Look into Non-Motor Phenotype and Glial Response. International Journal of Molecular Sciences. 2021
- Preclinical Evidence Supporting Early Initiation of Citalopram Treatment in Machado-Joseph Disease. Molecular Neurobiology. 2019
- Neurotoxic effects of MPTP on mouse cerebral cortex: Modulation of neuroinflammation as a neuroprotective strategy. Molecular and Cellular Neuroscience. 2019
- Citalopram Reduces Aggregation of ATXN3 in a YAC Transgenic Mouse Model of Machado-Joseph Disease. Molecular Neurobiology. 2018
- Tauroursodeoxycholic Acid Improves Motor Symptoms in a Mouse Model of Parkinson's Disease. Molecular Neurobiology. 2018
- Neuroprotective Effects of Creatine in the CMVMJD135 Mouse Model of Spinocerebellar Ataxia Type 3. Movement Disorders. 2018
- Discovery of Therapeutic Approaches for Polyglutamine Diseases: A Summary of Recent Efforts. Medicinal Research Reviews. 2017
- Combined therapy with m-TOR-dependent and -independent autophagy inducers causes neurotoxicity in a mouse model of Machado-Joseph disease. Neuroscience. 2016
- Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease. Brain. 2015
- Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease. PLoS ONE (IF=3.234). 2015
- Differential mtDNA Damage Patterns in a Transgenic Mouse Model of Machado-Joseph Disease (MJD/SCA3).. Journal of Molecular Neuroscience. 2015
- Selective impact of Tau loss on nociceptive primary afferents and pain sensation. Experimental Neurology. 2014
- Patterns of mitochondrial DNA damage in blood and brain tissues of a transgenic mouse model of Machado-Joseph disease. Neurodegenerative Diseases. 2013
- Motor uncoordination and neuropathology in a transgenic mouse model of Machado-Joseph disease lacking intranuclear inclusions and ataxin-3 cleavage products. Neurobiology of Disease. 2010
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artigo de conferência
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documento
- Bioactive extracts from brewer's spent grain. Food Bioscience. 2020
- Searching for therapeutic strategies in a mouse modelo of Machado-Joseph disease: targeting proteostases 2015
- Therapeutic strategies for polyQ diseases: from cellular and animal models to the clinic 2012
- Insights into pathology and neurodegeneration features in a transgenic mouse model of Machado-Joseph disease 2011
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livro