publicações selecionadas
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artigo académico
- Cognitive impairment in neurodegenerative diseases: A trans-diagnostic approach using a lesion-symptom mapping analysis. Neuroscience. 2025
- APOE genotype dictates lipidomic signatures in primary human hepatocytes. Journal of Lipid Research. 2024
- Lewy body co-pathology contributes to frontal lobe atrophy in Alzheimer’s disease and primary age-related tauopathy. Alzheimers & Dementia. 2023
- Early alterations in the MCH system link aberrant neuronal activity and sleep disturbances in a mouse model of Alzheimer’s disease. Nature Neuroscience. 2023
- Investigator-Led Clinical Research in Portugal: Problem Identification and Proposals for Improvement,Investigação Clínica da Iniciativa do Investigador em Portugal: Identificação de Problemas e Propostas para Melhoria. Acta Médica Portuguesa. 2023
- Sex-Specific Patterns of Cerebral Atrophy and Enlarged Perivascular Spaces in Patients with Cerebral Amyloid Angiopathy and Dementia. AJNR. American journal of neuroradiology. 2023
- Divergent magnetic resonance imaging atrophy patterns in Alzheimer's disease and primary age-related tauopathy. Neurobiology of Aging. 2022
- Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice. Elife. 2022
- Influence of Metabolic Syndrome on the Recovery from Idiopathic Sudden Sensorineural Hearing Loss. International Archives of Otorhinolaryngology. 2022
- Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects. Elife. 2021
- Intracerebral Hemorrhage Recurrence in Patients with and without Cerebral Amyloid Angiopathy. Cerebrovascular Diseases Extra. 2021
- Soccer heading and concussion are not associated with reduced brain volume or cortical thickness 2020
- Sphingolipids as prognostic biomarkers of neurodegeneration, neuroinflammation, and psychiatric diseases and their emerging role in lipidomic investigation methods. Advanced Drug Delivery Reviews. 2020
- Phospholipase D1 Ablation Disrupts Mouse Longitudinal Hippocampal Axis Organization and Functioning. Cell Reports. 2020
- Parkinson's Disease and Fabry Disease: Clinical, Biochemical and Neuroimaging Analysis of Three Pedigrees. Journal of Parkinson's Disease. 2020
- Differential lipid composition and regulation along the hippocampal longitudinal axis. Elife. 2019
- Magnetic resonance imaging brain atrophy assessment in primary age-related tauopathy (PART). Acta Neuropathologica Communications. 2019
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Effects of the LPA
1 receptor deficiency and stress on the hippocampal LPA species in mice. Frontiers in Molecular Neuroscience. 2019 - Phospholipase D functional ablation has a protective effect in an Alzheimer’s disease Caenorhabditis elegans model. Acta Cytologica. 2018
- Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures. Nature Communications. 2018
- Brain MRI in a patient with classical galactosemia: acute event of unilateral hemispheric cerebral edema. Child's Nervous System. 2017
- Ensino da Anatomia na Escola de Ciências da Saúde da Universidade do Minho 2016
- The impact of chronic stress on the rat brain lipidome. Elife. 2016
- Lipids under stress - A lipidomic approach for the study of mood disorders. BioEssays. 2015
- Differential impact of chronic stress along the hippocampal dorsal–ventral axis. Brain Structure and Function. 2015
- Lipocalin 2 modulates the cellular response to amyloid beta. Cell Death and Differentiation. 2014
- Dynamic myelopathy in Hirayama disease. Spine Journal. 2014
- Comparative lipidomic analysis of mouse and human brain with Alzheimer disease. Journal of Biological Chemistry. 2012
- Interplay between depressive-like behavior and the immune system in an animal model of prenatal dexamethasone administration. Acta Cytologica. 2011
- Phospholipase D in brain function and Alzheimer's disease. Biochimica et Biophysica Acta (BBA). Molecular and Cell Biology of Lipids. 2010
- Phospholipase D2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. Journal of Neuroscience. 2010
- How useful is the assessment of lymphatic vascular density in oral carcinoma prognosis?. World Journal of Surgical Oncology. 2007
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artigo de conferência
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capítulo de livro
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documento
- The impact of phospholipase D on APOE4 pathogenesis in the context of Alzheimer’s Disease 2025
- Using yeast to model phosphatidic acid-related pathways in lipid-mediated stress in Alzheimer's Disease pathogenesis 2024
- Bacteriophages to tackle Alzheimer´s disease 2024
- SorCS2 deletion leads to altered neuronal lysosome activity 2021
- The impact of PLD functional ablation in an Alzheimer's disease Caenorhabditis elegans model 2017
- The impact of phospholipase D functional ablation in physiology and in disease models in Caenorhabditis elegans 2017
- Ensino da Anatomia na Escola de Ciências da Saúde da Universidade do Minho. Archives of Anatomy. 2016
- The role of phospholipase D2 in Alzheimer's disease 2010
- Hippocampal lipids linked to brain disorders
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livro
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teses