publicações selecionadas
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artigo académico
- The potential of the fibronectin inhibitor RGDS in the development of therapies for glioblastoma. Biomolecules. 2024
- A transcriptomic profiling reveals novel roles of Cadherin-3 in metabolic programming of glioblastoma 2024
- A transcriptomic profiling reveals novel roles of Cadherin-3 in metabolic programming of glioblastoma - in final phase of preparation 2024
- Emerging roles and biomarker potential of WNT6 in human cancers. Theranostics. 2024
- Exploring Glioma Heterogeneity: Integrative Multi-Omics Analysis to Discover Transcriptome-Methylome signatures 2024
- Updating TCGA glioma subtype classification through integration of molecular profiling data following 2016 and 2021 WHO guidelines 2024
- WNT6 drives mechanisms of aggressiveness and resistance to chemotherapy in human glioblastoma - in final phase of preparation 2024
- Microfluidic-derived docosahexaenoic acid liposomes for glioblastoma therapy. Current Medicinal Chemistry. 2023
- Epigenetically-regulated miR-30a/c-5p directly target TWF1 and hamper ccRCC cell aggressiveness. Translational Research. 2022
- Cadherin-3 is a novel oncogenic biomarker with prognostic value in glioblastoma. Molecular Oncology. 2022
- Chronic Stress Does Not Influence the Survival of Mouse Models of Glioblastoma. Frontiers in Oncology. 2022
- Glioblastoma Vasculature: From its Critical Role in Tumor Survival to Relevant in Vitro Modelling. Frontiers in Drug Delivery. 2022
- Micro- to macroscale magnetic resonance imaging of glioma. Magnetic Resonance Materials in Physics, Biology, and Medicine. 2022
- Cadherin switches during epithelial-mesenchymal transition: CDH4/RCAD downregulation reduces bladder cancer progression. Cellular Oncology. 2022
- Bringing vascularization into glioblastoma in vitro models. Trends in Molecular Medicine. 2021
- PlexinA4 mediates cytotoxic T cell trafficking and exclusion in cancer. Cancer Immunology Research. 2021
- Adenosine inhibits cell proliferation differently in human astrocytes and in glioblastoma cell lines. Neuroscience. 2021
- Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage. Molecular Oncology. 2021
- Fucoidan/chitosan nanoparticles functionalized with anti-ErbB-2 target breast cancer cells and impair tumor growth in vivo. International Journal of Applied Pharmaceutics. 2021
- A novel molecular link between HOXA9 and WNT6 in glioblastoma identifies a subgroup of patients with particular poor prognosis. Molecular Oncology. 2020
- MicroRNA-30a-5pme: a novel diagnostic and prognostic biomarker for clear cell renal cell carcinoma in tissue and urine samples. Journal of Experimental & Clinical Cancer Research. 2020
- HOX gene cluster (de)regulation in brain: from neurodevelopment to malignant glial tumours. Cellular and Molecular Life Sciences. 2020
- Large expert-curated database for benchmarking document similarity detection in biomedical literature search. Database. 2019
- The cell secretome in personalized and regenerative medicine.. Biochimie. 2018
- CBIO-18. HAPLOINSUFFICIENCY OF THE REGULATOR OF THE MUTANT TERT PROMOTER REVERSES GLIOBLASTOMA REPLICATIVE IMMORTALITY. Neuro-Oncology. 2016
- Insights into angiogenesis in non-small cell lung cancer: Molecular mechanisms, polymorphic genes, and targeted therapies. Recent Patents on Anti-Cancer Drug Discovery. 2012
- Prognostic value of MGMT promoter methylation in glioblastoma patients treated with temozolomide-based chemoradiation: A Portuguese multicentre study. Oncology Reports. 2010
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artigo de revista
- MCT1 Is a New Prognostic Biomarker and Its Therapeutic Inhibition Boosts Response to Temozolomide in Human Glioblastoma. Cancers. 2021
- A New Chalcone Derivative with Promising Antiproliferative and Anti-Invasion Activities in Glioblastoma Cells. Biomolecules. 2021
- The Role of Network Science in Glioblastoma. Cancers. 2021
- Intracellular Autofluorescence as a New Biomarker for Cancer Stem Cells in Glioblastoma. Cancers. 2021
- Glioblastoma: Is There Any Blood Biomarker with True Clinical Relevance?. International Journal of Molecular Sciences. 2020
- Exploiting the Complexities of Glioblastoma Stem Cells: Insights for Cancer Initiation and Therapeutic Targeting. International Journal of Molecular Sciences. 2020
- Unravelling the anticancer potential of functionalized chromeno[2,3-b]pyridines for breast cancer treatment. Bioorganic Chemistry. 2020
- Sirtuins' Deregulation in Bladder Cancer: SIRT7 Is Implicated in Tumor Progression through Epithelial to Mesenchymal Transition Promotion. Cancers. 2020
- Overexpression of circulating MiR-30b-5p identifies advanced breast cancer. Journal of Translational Medicine. 2019
- Serum lactate levels are associated with glioma malignancy grade. Clinical Neurology and Neurosurgery. 2019
- WNT6 is a novel oncogenic prognostic biomarker in human glioblastoma. Theranostics. 2018
- Disruption of the ß1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner. Cancer Cell. 2018
- The impact of Mesenchymal Stem Cells and their secretome as a treatment for gliomas.. Biochimie. 2018
- A multiplatform approach identifies miR-152-3p as a common epigenetically regulated onco-suppressor in prostate cancer targeting TMEM97. Clinical Epigenetics. 2018
- The long non-coding RNA HOTAIR is transcriptionally activated by HOXA9 and is an independent prognostic marker in patients with malignant glioma. Oncotarget. 2018
- Influence of HOTAIR rs920778 and rs12826786 genetic variants on prostate cancer risk and progression-free survival. Biomarkers in Medicine. 2018
- SETDB2 and RIOX2 are differentially expressed among renal cell tumor subtypes, associating with prognosis and metastization. Epigenetics. 2017
- Loss of Caveolin-1 in Metastasis-Associated Macrophages Drives Lung Metastatic Growth through Increased Angiogenesis. Cell Reports. 2017
- Crosstalk between glial and glioblastoma cells triggers the "go-or-grow" phenotype of tumor cells. Cell Communication and Signaling. 2017
- Impact of mesenchymal stem cells' secretome on glioblastoma pathophysiology. Journal of Translational Medicine. 2017
- A semiautomated microfluidic platform for real-time investigation of nanoparticles cellular uptake and cancer cells tracking. Analytical Chemistry. 2017
- Effects of the functional HOTAIR rs920778 and rs12826786 genetic variants in glioma susceptibility and patient prognosis. Journal of Neuro-Oncology. 2017
- Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas. Oncotarget. 2016
- Histone methyltransferase PRMT6 plays an oncogenic role of in prostate cancer. Oncotarget. 2016
- Understanding TERT promoter mutations: A common path to immortality. Molecular Cancer Research. 2016
- Variant Rett syndrome in a girl with a pericentric X-chromosome inversion leading to epigenetic changes and overexpression of the MECP2 gene. International Journal of Developmental Neuroscience. 2015
- Expression of histone methyltransferases as novel biomarkers for renal cell tumor diagnosis and prognostication. Epigenetics. 2015
- Transcriptional profiling of HOXA9-regulated genes in human glioblastoma cell models. Genomics Data. 2015
- Mesenchymal stem cells secretome as a modulator of the neurogenic niche: Basic insights and therapeutic opportunities. Frontiers in Cellular Neuroscience. 2015
- MicroRNA-375 plays a dual role in prostate carcinogenesis. Clinical Epigenetics. 2015
- MicroRNA-375 plays a dual role in prostate carcinogenesis. Clinical Epigenetics. 2015
- Impact of TGF-ß1 -509C/T and 869T/C polymorphisms on glioma risk and patient prognosis. Tumor Biology. 2015
- A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide. Oncotarget. 2015
- The tumoral A genotype of the MGMT rs34180180 single-nucleotide polymorphism in aggressive gliomas is associated with shorter patients' survival. Carcinogenesis. 2015
- In vitro evaluation of the cytotoxicity and cellular uptake of CMCht/PAMAM dendrimer nanoparticles by glioblastoma cell models. Journal of Nanoparticle Research. 2013
- Molecular prognostic factors in glioblastoma: state of the art and future challenges. Cns Oncology. 2013
- Association between EGF +61 genetic polymorphisms and non-small cell lung cancer increased risk in a Portuguese population: A case-control study. Tumor Biology. 2012
- Insights into angiogenesis in non-small cell lung cancer : molecular mechanisms, polymorphic genes, and targeted therapies. Recent Patents on Anti-Cancer Drug Discovery. 2012
- Insights into angiogenesis in non-small cell lung cancer: molecular mechanisms, polymorphic genes, and targeted therapies.. Recent Patents on Anti-Cancer Drug Discovery. 2012
- Mechanisms of initiation and reversal of drug-seeking behavior induced by prenatal exposure to glucocorticoids. Elife. 2012
- Mechanisms of initiation and reversal of drug-seeking behavior induced by prenatal exposure to glucocorticoids. Elife. 2012
- Association between EGF +61A/G polymorphism and gastric cancer in Caucasians.. World Journal of Gastroenterology. 2011
- Association between EGF +61A/G polymorphism and gastric cancer in Caucasians.. World Journal of Gastroenterology. 2011
- Impact of EGFR genetic variants on glioma risk and patient outcome. Cancer Epidemiology Biomarkers & Prevention. 2011
- Impact of EGFR genetic variants on glioma risk and patient outcome. Cancer Epidemiology Biomarkers & Prevention. 2011
- Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma. Neuro-Oncology. 2011
- Prognostic value of MGMT promoter methylation in glioblastoma patients treated with temozolomide-based chemoradiation: A Portuguese multicentre study. Oncology Reports. 2010
- Reversing HOXA9 oncogene activation by PI3K inhibition: Epigenetic mechanism and prognostic significance in human glioblastoma. Cancer Research. 2010
- Reversing HOXA9 oncogene activation by PI3K inhibition: Epigenetic mechanism and prognostic significance in human glioblastoma. Cancer Research. 2010
- Association between functional EGF+61 polymorphism and glioma risk. Clinical Cancer Research. 2007
- Association between functional EGF+61 polymorphism and glioma risk. Clinical Cancer Research. 2007
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capítulo de livro
- The Impact of Technological Implementation Decisions on Job-Shop Scheduling Simulator Performance Using Secondary Storage and Parallel Processing 2022
- Mechanisms of Aggressiveness in Glioblastoma: Prognostic and Potential Therapeutic Insights 2013
- Molecular Pathology of Glioma 2012
- Molecular Hallmarks of Gliomas 2011
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documento
- Deciphering WNT6-driven mechanisms of aggressiveness and resistance to chemotherapy in human glioblastoma 2024
- Deciphering novel mechanisms of WNT6-driven chemotherapy resistance in human glioblastoma 2023
- A transcriptomic profiling reveals novel roles of Cadherin-3 in metabolic programming of glioblastoma 2023
- Unveiling the impact of the oncogenic molecule Cadherin-3 in the metabolism of human glioblastoma 2023
- Unveiling the impact of the oncogenic molecule Cadherin-3 in themetabolism of human glioblastoma 2023
- Role of the ubiquitin hydrolase ATXN3 in glioblastoma: a new tumor suppressor gene? 2022
- Concerted metabolic and transcriptomic rewiring dictates gliioblastoma cells survival and stemness 2022
- A new lead compound for triple negative breast cancer therapy 2021
- A new therapeutic option for triple negative breast cancer 2021
- Characterization of the biological activity of functionalized chromeno[2,3b]pyridines for breast cancer treatment 2020
- New chromene derivatives: unravelling the molecular mechanisms for breast cancer treatment 2019
- PO-473 Wnt6 expression in glioblastoma: mechanistic, functional and clinical implications 2018
- Reconstruction of consensus tissue-specific metabolic models 2018
- PO-105 Cdh3/p-cadherin as a novel biomarker in glioblastoma: functional and prognostic insights 2018
- PO-297 Plexina4 plays a role in cancer progression and immune cell infiltration 2018
- Intracellular autofluorescence: a new biomarker for Glioblastoma Stem Cells 2017
- A microfluidic platform for the investigation of cancer cells’ nanoparticle uptake and real time tracking 2017
- Intracellular autofluorescence: a new biomarker for Glioblastoma Stem Cells” 2017
- Autofluorescence as a new biomarker to identify glioblastoma stem cells 2016
- Regulation of WNT6 by HOXA9 in glioblastoma: functional and clinical relevance 2016
- Anticancer profile of a selection of new chromene-based compounds 2015
- HOXA9 promotes glioblastoma initiation, aggressiveness and resistance to therapy 2014
- WNT6 promoter methylation associates with its expression in glioblastoma 2014
- Regulation of Wnt signaling by HOXA9 in Glioblastoma: Mechanistic and Prognostic Insights 2013
- Relevance of HES1 expression in human gliomas: molecular and clinical correlates 2013
- Regulation of WNT signaling by HOXA9 in glioblastoma: mechanistic, prognostic and therapeutic insights 2013
- Long Non-Coding RNA HOTAIR is Transcriptionally Activated by HOXA9 and Is Associated with Poor Prognosis in Glioblastoma 2013
- Understanding how the secretome of human bone marrow-derived mesenchymal stem cells modulates glioblastoma cells 2013
- HOXA9 target genes in Glioblastoma: characterization and clinical relevance 2012
- Regulation of WNT6 expression by HOXA9 in glioblastoma and prognostic implications 2012
- HOXA9 transcriptome analysis in Glioblastoma: The bioinformatics beyond the bench 2012
- 165 Influence of HOXA9 Expression in the Response of Glioblastoma Cells to Temozolomide 2012
- 565 HOXA9 Target Genes in Glioblastoma – Characterization and Clinical Relevance 2012
- 9139 POSTER Association Between +61 A/G Polymorphism in the EGF Gene and Non-Small Cell Lung Cancer Risk in Male Caucasians 2011
- 95 Associations between functional EGFR polymorphisms and glioma risk 2010
- Epigenetic activation of HOXA9 due to PI3K pathway dysfunction has functional and clinical relevance in human tumors 2008
- A novel prognostic subgroup of glioblastoma with activated HOX domains that are reversibly regulated through the PI3k pathway 2007
- Association Between Functional EGF+61 Polymorphism and Glioma Risk 2007
- Chromosomal domains of transcriptional activation by P13K/AKT pathway alterations in glioblastomas 2007
- Presence of factors predictive of response to anti-EGFR therapy in pediatric high-grade gliomas. 2007
- No association between EGFR promoter gene polymorphisms and glioma risk. 2006
- Updating TCGA glioma classification through integration of molecular profiling data following the 2016 and 2021 WHO guidelines
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