Publicações no PortAberta

Co-autor de rede

Mapa da Ciência

Costa, Marta Daniela Araújo

Membro do Corpo Docente e de Investigadores

posições

Instituto de Investigação em Ciências da Vida e Saúde 2019 -

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publicações selecionadas

artigo académico
- Glucocorticoid receptor-dependent therapeutic efficacy of tauroursodeoxycholic acid in preclinical models of Spinocerebellar ataxia type 3. Journal of Clinical Investigation. 2024
- Glucocorticoid receptor-dependent therapeutic efficacy of tauroursodeoxycholic acid in preclinical models of Spinocerebellar ataxia type 3 (IF: 19.47). The Journal of Clinical Investigation. 2024
- Mitochondrial Dysfunction and Decreased Cytochrome c in Cell and Animal Models of Machado-Joseph Disease. Cells. 2023
- Synthesis and Biological Evaluation of Novel Chromeno[2,3-d]Pyrimidinones as Agents for Triple Negative Breast Cancer Treatment. European Journal of Medicinal Chemistry (IF 7.08, Q1 Chemistry, Organic). 2023
- Modifier pathways in polyglutamine (PolyQ) diseases: from genetic screens to drug targets (IF: 8.0). Cellular and Molecular Life Sciences. 2022
- Modifier pathways in Polyglutamine (PolyQ) diseases: from genetic screens to drug targets. Cellular and Molecular Life Sciences. 2022
- Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing. Neurobiology of Disease. 2022
- Case Report: A Novel GNB1 Mutation Causes Global Developmental Delay With Intellectual Disability and Behavioral Disorders. Frontiers in Neurology. 2021
- Identification of the 5-HT1A serotonin receptor as a novel therapeutic target in a C. elegans model of Machado-Joseph disease. Neurobiology of Disease. 2021
- Loss of egli-1, the Caenorhabditis elegans Orthologue of a Downstream Target of SMN, Leads to Abnormalities in Sensorimotor Integration. Molecular Neurobiology. 2020
- A substantial prehistoric European ancestry amongst Ashkenazi maternal lineages (IF: 10.742). Nature Communications. 2013
- The Arabian Cradle: Mitochondrial Relicts of the First Steps along the Southern Route out of Africa (IF: 11.202). American Journal of Human Genetics. 2012
- The Expansion of mtDNA Haplogroup L3 within and out of Africa (IF: 5.55). Molecular Biology and Evolution. 2011
- Population expansion in the North African Late Pleistocene signalled by mitochondrial DNA haplogroup U6. BMC Evolutionary Biology. 2010
- The trans-Saharan slave trade - clues from interpolation analyses and high-resolution characterization of mitochondrial DNA lineages (IF: 3.702). BMC Evolutionary Biology. 2010
- Post-last glacial maximum expansion from Iberia to North Africa revealed by fine characterization of mtDNA H haplogroup in Tunisia (IF: 2.756). American Journal of Physical Anthropology. 2009
- The Diversity Present in 5140 Human Mitochondrial Genomes (IF: 12.303). American Journal of Human Genetics. 2009
- Data from complete mtDNA sequencing of Tunisian centenarians: Testing haplogroup association and the “golden mean” to longevity (IF: 4.179). Mechanisms of Ageing and Development. 2009
- Migration of Chadic speaking pastoralists within Africa based on population structure of Chad Basin and phylogeography of mitochondrial L3f haplogroup (IF:4.294). BMC Evolutionary Biology. 2009
artigo de conferência
- mtDNA diversity in Sudan (East Africa) 2008
artigo de revista
- Aripiprazole Offsets Mutant ATXN3-Induced Motor Dysfunction by Targeting Dopamine D2 and Serotonin 1A and 2A Receptors in C. elegans. Biomedicines. 2022
- Neurotherapeutic effect of Hyptis spp. leaf extracts in Caenorhabditis elegans models of tauopathy and polyglutamine disease: Role of the glutathione redox cycle. Free Radical Biology and Medicine. 2021
- Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases. Data in Brief. 2020
- Unravelling the anticancer potential of functionalized chromeno[2,3-b]pyridines for breast cancer treatment. Bioorganic Chemistry. 2020
- GST-4-Dependent Suppression of Neurodegeneration in C. elegans Models of Parkinson's and Machado-Joseph Disease by Rapeseed Pomace Extract Supplementation. Frontiers in Aging Neuroscience. 2019
- Origin and spread of human mitochondrial DNA haplogroup U7 (IF: 5.228). Acta Cytologica. 2017
- Reconciling evidence from ancient and contemporary genomes: a major source for the European Neolithic within Mediterranean Europe (IF: 4.847). Proceedings of the Royal SocIETy B-Biological Sciences. 2017
- Fine Time Scaling of Purifying Selection on Human Nonsynonymous mtDNA Mutations Based on the Worldwide Population Tree and Mother-Child Pairs. Human Mutation. 2015
- Novel structurally similar chromene derivatives with opposing effects on p53 and apoptosis mechanisms in colorectal HCT116 cancer cells. European Journal of Pharmaceutical Sciences. 2015
- Polishing Domestic Wastewater on a Subsurface Flow Constructed Wetland: Organic Matter Removal and Microbial Monitoring. International Journal of Phytoremediation. 2011
documento
teses
- Genetic characterisation of the Early Upper Palaeolithic settlement of Europe by modern humans 2013
- Microbiological characterization of the wastewater Phragmites australis rizhospere in a constructed wetland from the north of Portugal. 2008