publicações selecionadas
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artigo académico
- Dispersal history of SARS-CoV-2 in Galicia, Spain. Journal of Medical Virology. 2024
- Breaking Boundaries in Malaria Research: Design of a Genetic Tool for High-Throughput Gametocidal Drug Screening. Journal UMinho Science. 2024
- Artemisinin resistance-associated gene mutations in Plasmodium falciparum: A case study of severe malaria from Mozambique. Travel Medicine and Infectious Disease. 2023
- Development of polyurethane antimicrobial coatings by composition with phenolic-, ionic- and copper-based agents. Journal of Materials Research and Technology. 2023
- PMMA Microcapsules for the Inactivation of SARS-CoV-2. ACS Omega. 2022
- Plasmodium falciparum Drug Resistance Genes pfmdr1 and pfcrt In Vivo Co-Expression During Artemether-Lumefantrine Therapy. Frontiers in Pharmacology. 2022
- Chloroquine-susceptible and -resistant Plasmodium falciparum strains survive high chloroquine concentrations by becoming dormant but are eliminated by prolonged exposure. Journal of Antimicrobial Chemotherapy. 2022
- SARS-CoV-2 introductions and early dynamics of the epidemic in Portugal. Communications Medicine. 2022
- Massive dissemination of a SARS-CoV-2 Spike Y839 variant in Portugal. Emerging Microbes & Infections. 2020
- Mycobacterium tuberculosis associated with severe tuberculosis evades cytosolic surveillance systems and modulates IL-1ß production. Nature Communications. 2020
- Rapid phenotyping towards personalized malaria medicine. Malaria Journal. 2020
- Multigenic architecture of piperaquine resistance trait in Plasmodium falciparum. Lancet Infectious Diseases. 2020
- Plasmodium falciparum Plasmepsin 2 Duplications, West Africa. Emerging Infectious Diseases. 2018
- Dosage of single low-dose primaquine to stop malaria transmission. Journal of Infectious Diseases. 2018
- Drug resistance associated genetic polymorphisms in Plasmodium falciparum and Plasmodium vivax collected in Honduras, Central America. Malaria Journal. 2011
- Novel Polymorphisms in Plasmodium falciparum ABC Transporter Genes Are Associated with Major ACT Antimalarial Drug Resistance. Antibiotics. 2011
- PfMDR1: Mechanisms of Transport Modulation by Functional Polymorphisms. Antibiotics. 2011
- Plasmodium falciparum population dynamics during the early phase of anti-malarial drug treatment in Tanzanian children with acute uncomplicated malaria. Malaria Journal. 2011
- Prevalence of resistance associated polymorphisms in Plasmodium falciparum field isolates from southern Pakistan. Malaria Journal. 2011
- Antimalarial Exposure Delays Plasmodium falciparum Intra-Erythrocytic Cycle and Drives Drug Transporter Genes Expression. Antibiotics. 2010
- In Vivo Selection of Plasmodium falciparum Parasites Carrying the Chloroquine-Susceptible pfcrt K76 Allele after Treatment with Artemether-Lumefantrine in Africa. J. Infect. Dis.. 2009
- Pharmacogenomics of CYP2A6, CYP2B6, CYP2C19, CYP2D6, CYP3A4, CYP3A5 and MDR1 in Vietnam. European Journal of Clinical Pharmacology. 2009
- Plasmodium falciparum Multidrug Resistance Protein 1 and Artemisinin-Based Combination Therapy in Africa. J. Infect. Dis.. 2009
- Polymorphism in PfMRP1 (Plasmodium falciparum Multidrug Resistance Protein 1) Amino Acid 1466 Associated with Resistance to Sulfadoxine-Pyrimethamine Treatment. Antimicrob. Agents Chemother.. 2009
- Antimalarial resistance and DHFR/DHPS genotypes of Plasmodium falciparum three years after introduction of sulfadoxine-pyrimethamine and amodiaquine in rural Tanzania. Transactions of the Royal SocIETy of Tropical Medicine and Hygiene. 2008
- Diversity of the sarco/endoplasmic reticulum Ca2+-ATPase orthologue of Plasmodium falciparum (PfATP6). Infection, Genetics and Evolution. 2008
- Polymorphism of antimalaria drug metabolizing, nuclear receptor, and drug transport genes among malaria patients in Zanzibar, East Africa. Ther. Drug Monit.. 2008
- Influence of consecutive-day blood sampling on polymerase chain reaction-adjusted parasitological cure rates in an antimalarial-drug trial conducted in Tanzania. Journal of Infectious Diseases. 2007
- The Vietnamese Khin population harbors particular N-acetyltransferase 2 allele frequencies. Clinical Chemistry. 2007
- Amodiaquine resistant Plasmodium falciparum malaria in vivo is associated with selection of pfcrt 76T and pfmdr1 86Y. Infect. Genet. Evol.. 2006
- Multiplex PCR-RFLP methods for pfcrt, pfmdr1 and pfdhfr mutations in Plasmodium falciparum. Molecular and Cellular Probes. 2006
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artigo de conferência
- Breaking Boundaries in Malaria Research: Design of a Genetic Tool for High-Throughput Gametocidal Drug Screening 2024
- Design of a two-fluorophore pH biosensor targeted to the digestive vacuole of Plasmodium falciparum 2023
- Effect of the Materials' Properties in the Design of High Transmittance and Low FWHM SiO2/TiO2 Thin Film Optical Filters for Integration in a Malaria Diagnostics Device 2021
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artigo de revista
- CMOS Spectrophotometric Microsystem for Malaria Detection. IEEE Transactions on Biomedical Engineering. 2023
- Extensional flow for assessing the effect of nanocarriers on the mechanical deformability of red blood cells. Experimental Thermal and Fluid Science. 2023
- Cerebral Malaria Model Applying Human Brain Organoids. Cells. 2023
- Optical Spectrophotometry as a Promising Method for Quantification and Stage Differentiation of Plasmodium falciparum Parasites. ACS Infectious Diseases. 2023
- Development of an Ultraviolet-C Irradiation Room in a Public Portuguese Hospital for Safe Re-Utilization of Personal Protective Respirators. Healthcare. 2022
- Review of Microdevices for Hemozoin-Based Malaria Detection. Biosensors. 2022
- The Future in Sensing Technologies for Malaria Surveillance: A Review of Hemozoin-Based Diagnosis. ACS Sensors. 2021
- OmniSARS2: A Highly Sensitive and Specific RT-qPCR-Based COVID-19 Diagnostic Method Designed to Withstand SARS-CoV-2 Lineage Evolution. Biomedicines. 2021
- Multilayer Thin-Film Optical Filters for Reflectance-Based Malaria Diagnostics. Micromachines. 2021
- Expansion of a Specific Plasmodium falciparum PfMDR1 Haplotype in Southeast Asia with Increased Substrate Transport. Mbio. 2020
- Portable Device for Optical Quantification of Hemozoin in Diluted Blood Samples. IEEE Transactions on Biomedical Engineering. 2020
- Portable Device for Optical Quantification of Hemozoin in Diluted Blood Samples. IEEE Transactions on Biomedical Engineering. 2020
- Plasmodium falciparum K13 expression associated with parasite clearance during artemisinin-based combination therapy. Journal of Antimicrobial Chemotherapy. 2019
- Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity. Nature Microbiology. 2017
- Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies.. Nature Communications. 2016
- Complex Polymorphisms in the Plasmodium falciparum Multidrug Resistance Protein 2 Gene and Its Contribution to Antimalarial Response. Antimicrobial Agents and Chemotherapy. 2014
- Single nucleotide polymorphisms in Plasmodium falciparum V type H(+) pyrophosphatase gene (pfvp2) and their associations with pfcrt and pfmdr1 polymorphisms.. Infection, Genetics and Evolution. 2014
- pfmdr1 Amplification Is Related to Increased Plasmodium falciparum In Vitro Sensitivity to the Bisquinoline Piperaquine. Antimicrob. Agents Chemother.. 2012
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capítulo de livro
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documento
- Red Fluorescent & Luminescent Malaria Parasites: A Novel Tool for High-Throughput Gametocidal Drug Screening 2024
- Anemia hemolítica autoimune VS Síndrome neurológica após tratamento com artesunato em pacientes com malária por Plasmodium falciparum, na Clínica Multiperfil entre Junho e Agosto de 2023 Luanda/Angola: relato de 6 casos. 2024
- Engenharia de Parasitas da Malária Humana para triagem de drogas em multiplas etapas de alto rendimento 2024
- Nanocarrier-based microfluidic system for characterization of malaria infected-cells 2024
- Enginnering a Transgenic Human Malaria Parasite Reporter Line for Multistage Drug Screening 2024
- Methods in Molecular biology: CRISPR-engineered drug-resistant human malaria parasites 2024
- Breaking Boundaries in Malaria Research: Design of a Genetic Tool for High-Throughput Gametocidal Drug Screening 2024
- Engineering Resistance: Using the CRISPR-Cas9 system to generate drug-resistant human malaria parasites 2024
- Engineering Human Malaria Parasites for Highthroughput Gametocidal Drug Screening 2024
- Enhancing malaria elimination strategies in the Dominican Republic: Evaluating rapid diagnostic test accuracy and unraveling parasite genetic diversity 2024
- On-chip optical microsystem for Plasmodium Falciparum malaria detection 2024
- The CRISPR-Cas9 system as a tool for genetic engineering in the malaria parasite 2023
- Dissecting the role of lipocalin in Plasmodium falciparum 2023
- Assessing malaria rapid diagnostic test accuracy and genetic diversity in the Dominican Republic: Implications for elimination efforts 2023
- Plasmodium falciparum heme species dynamics under antimalarial exposure 2023
- Deeper into hemozoin formation pathway of Plasmodium falciparum 2022
- Optical spectrophotometry into hemozoin: towards sensitive malaria diagnosis 2022
- Hemozoin: the key for malarial control and elimination 2022
- Research Highlights Featuring the Paper: "Review of Microdevices for Hemozoin-Based Malaria Detection" (doi: 10.3390/bios12020110) 2022
- The Plasmodium falciparum protein PfMRP1 functions as an influx ABC transporter 2022
- Disclosure Of Pfmrp1 As An Influx ABC Transporter Protein In Plasmodium Falciparum 2021
- DISCLOSURE OF AN INFLUX ABC TRANSPORTER PROTEIN IN PLASMODIUM FALCIPARUM 2020
- Expansion of Plasmodium falciparum specific pfmdr1 gene copy haplotype in Southeast-Asia with increased transport kinetics 2020
- Oxysterols: synthesis and antimalarial drug potency 2020
- Hemozoin: the future in malaria diagnosis 2020
- Characterization of the malaria parasite optical features for development of a non-invasive diagnostic device 2019
- Tuberculosis severity and its association with pathogen phylogeny and properties 2017
- ZINC-FINGER NUCLEASE-MEDIATED GENE EDITING ILLUSTRATES THE ROLE OF PFMDR1 N86Y IN MODULATING PLASMODIUM FALCIPARUM SUSCEPTIBILITY TO ARTEMISININ-BASED COMBINATION THERAPIES 2017
- Molecular genotypes and clearance of different: 1.1-142P. falciparum: 1.1-142sub populations in children treated with ACT: 1.1-142 2011
- Molecular genotypes and clearance of different P. falciparum sub populations in children treated with ACT 2011
- Antimalarial calcium-signaling induction in Plasmodium falciparum 2008
- Antimalarial calcium-signaling induction in Plasmodium falciparum. 2008
- In vivo selection of P-falciparum parasites carrying the pfcrt 76K allele upon treatment with artemether-lumefantrine 2008
- Pfmdr1 gene expression during all Plasmodium falciparum erythrocyte cycle with mefloquine pressure 2008
- The role of Plasmodium falciparum multidrug resistance-associated protein 1 (pfmrp1) in development of resistance to artemisinin-based combination therapies (ACTs) 2008
- The role of Plasmodium falciparum multidrug resistance-associated protein 1 (pfmrp1) in development of resistance to artemisinin-based combination therapies (ACTs). 2008
- The sarco/endoplasmic reticulum Ca2+-ATPase orthologue of Plasmodium falciparum (PfATP6) harbours high SNP diversity 2008
- The sarco/endoplasmic reticulum Ca2+-ATPase orthologue of Plasmodium falciparum (PfATP6) harbours high SNP diversity. 2008
- Polymorphisms of drug metabolising, nuclear receptor and drug transport genes among malaria patients in Zanzibar: PB 60 2007
- Polymorphisms of drug metabolising, nuclear receptor and drug transport genes among malaria patients in Zanzibar 2007
- Biomedical Research During the COVID-19 Pandemic: Success in Sars-Cov-2 and Other Infectious Diseases
- Emergence of Plasmodium Falciparum Strain with Reduced Susceptibility to Artemisinin-Based Combination Therapy Drugs: A Case Study from Mozambique
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teses