publicações selecionadas
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artigo académico
- The fungicide cymoxanil impairs respiration in Saccharomyces cerevisiae via cytochrome c oxidase inhibition. FEBS Letters. 2024
- Heterologous expression and structure prediction of a xylanase identified from a compost metagenomic library. Applied Microbiology and Biotechnology. 2024
- Current and Novel Approaches in Yeast Cell Death Research. Cell Death and Differentiation. 2024
- Enhancement of Acetate-Induced Apoptosis of Colorectal Cancer Cells by Cathepsin D Inhibition Depends on Oligomycin A-Sensitive Respiration. Biomolecules. 2024
- Exosomes modified with anti-MEK1 siRNA lead to an effective silencing of triple negative breast cancer cells. Biomaterials Advances. 2023
- Functional and sequence-based metagenomics to uncover carbohydrate-degrading enzymes from composting samples. Applied Microbiology and Biotechnology. 2023
- Bovine Lactoferrin-Loaded Plasmonic Magnetoliposomes for Antifungal Therapeutic Applications. Pharmaceutics. 2023
- Plasmalemmal V-ATPase as a Potential Biomarker for Lactoferrin-Based Anticancer Therapy. Biomolecules. 2022
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artigo de conferência
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artigo de revista
- Synthesis and Cytotoxicity Assessment of Citrate-Coated Calcium and Manganese Ferrite Nanoparticles for Magnetic Hyperthermia. Pharmaceutics. 2022
- Lactoferrin perturbs intracellular trafficking, disrupts cholesterol-rich lipid rafts and inhibits glycolysis of highly metastatic cancer cells harbouring plasmalemmal V-ATPase. International Journal of Biological Macromolecules. 2022
- Acetic acid triggers cytochrome c release in yeast heterologously expressing human Bax. Apoptosis. 2022
- A review on lactoferrin as a proton pump inhibitor. International Journal of Biological Macromolecules. 2022
- Saccharomyces cerevisiae Cells Lacking the Zinc Vacuolar Transporter Zrt3 Display Improved Ethanol Productivity in Lignocellulosic Hydrolysates. Journal of Fungi. 2022
- Identification of novel aptamers targeting Cathepsin B-overexpressing prostate cancer cells. Molecular Systems Design & Engineering. 2022
- The milk-derived lactoferrin inhibits V-ATPase activity by targeting its V1 domain. International Journal of Biological Macromolecules. 2021
- Regulation of Cell Death Induced by Acetic Acid in Yeasts. Frontiers in Cell and Developmental Biology. 2021
- Lactoferrin perturbs lipid rafts and requires integrity of Pma1p-lipid rafts association to exert its antifungal activity against Saccharomyces cerevisiae. International Journal of Biological Macromolecules. 2021
- Emerging insights on the role of V-ATPase in human diseases: Therapeutic challenges and opportunities. Medicinal Research Reviews. 2021
- Selection of a new peptide homing SK-BR-3 breast cancer cells. Chemical Biology & Drug Design. 2020
- Resveratrol-Loaded Lipid Nanocarriers Are Internalized By Endocytosis in Yeast. Journal of Natural Products. 2019
- Effect of microstructural changes in the biological behavior of magnetron sputtered ZnO thin films. Journal of Vacuum Science & Technology A. 2019
- Bovine Milk Lactoferrin Selectively Kills Highly Metastatic Prostate Cancer PC-3 and Osteosarcoma MG-63 Cells In Vitro. Frontiers in Oncology. 2018
- Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemmal V-H+-ATPase. Oncotarget. 2016
- Human lactoferrin triggers a mitochondrial- and caspase-dependent regulated cell death in Saccharomyces cerevisiae. Apoptosis. 2015
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capítulo de livro
- Metagenomics to unravel the microbial biodiversity and biotechnological potential of extreme high salinity environments 2024
- Metagenomics to unravel the microbial biodiversity and biotechnological potential of extreme high salinity environments 2022
- O potencial oculto da matéria negra microbiana 2022
- Flow Cytometry and Fluorescence Microscopy as Tools for Structural and Functional Analysis of Vacuoles Isolated from Yeast and Plant Cells. Methods in Molecular Biology. 2018
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documento
- Promising Biosurfactants from Biodiversity and Bioprospection Studies in Underexplored Hypersaline Environments 2024
- Exploring Lactoferrin-loaded Exosomes as a Novel Therapeutic Strategy for Colorectal Cancer 2024
- The cymoxanil fungicide impairs Saccharomyces cerevisiae respiration via complex IV inhibition 2024
- The hidden potential of hypersaline environments: extremophiles as source of new biosurfactants 2024
- Uncovering novel carbohydrate-degrading enzymes from composting units through metagenomic strategies 2024
- Harnessing the quest for eco-friendly alternatives to chemical surfactants by exploring extreme salinity environments 2023
- Exploring the microbiology of high-salinity Mars analog sites as a source of novel strains relevant for Astrobiology and Space Biotechnology 2023
- Uncovering new biosurfactants from Iberian hypersaline environments through metagenomics 2023
- Lactoferrin-loaded magnetoliposomes for triple negative breast cancer treatment 2023
- Magnetolipossomas carregados com lactoferrina para tratamento do cancro da mama triplo-negativo 2023
- Deciphering the interplay between autophagy and the milk-derived lactoferrin protein 2023
- Exploring the potential of new 6-hydrazinopurine as effective anticancer agents 2023
- Unraveling the potential of lactoferrin-loaded magnetoliposomes for breast cancer therapy 2023
- Cymoxanil inhibits respiration through inhibition of mitochondrial complex IV 2023
- dentification of lignocellulose-degrading enzymes using metagenomic approaches 2023
- Identification of lignocellulose-degrading enzymes using metagenomic approaches 2023
- Biodiversity and Bioprospection of Biosurfactants in Saline Environments 2023
- Unveiling the anticancer potential of 6-hydrazinopurines 2023
- Lactoferrin-loaded extracellular vesicles as a potential treatment against triple negative breast cancer 2023
- Exploring Aveiro salterns to discover new and robust biosurfactant-producing microorganisms 2023
- Exploring Aveiro salterns to discover new and robust biosurfactant producers 2023
- Metagenomic approach to identify genes encoding for glycoside hydrolases in composting samples 2023
- Mining bioactive molecules from extreme environments using sequence-based metagenomics 2023
- Bioprospection of biosurfactant-producing microbes from Portuguese salterns 2022
- Image processing tool for the detection and quantification of xylanase activity in a metagenomic study 2022
- Bioprospection of novel biosurfactants from hypersaline locations 2022
- Bridging the gap between lactoferrin and V-ATPase through a multi-stage computational approach 2021
- Integrated biochemical and computational approach reveals novel mechanisms underlying the antifungal activity of the milk-derived lactoferrin protein 2021
- Acetic acid as a trigger to activate human Bax heterologously expressed in yeast 2021
- Elucidating the interaction of lactoferrin with V-ATPase towards understanding its mechanisms of action 2021
- Computational approach to study the interaction between the milk protein lactoferrin and V-ATPase 2019
- Lactoferrin is selectively cytotoxic for highly metastatic cancer cells by inhibiting plasmalemmal V-ATPase 2019
- The impact of zinc in yeast cell death induced by acetic acid 2019
- Which molecular mechanisms are involved in the antifungal activity of the milk-derived protein lactoferrin? 2019
- The role of membrane lipid domains on lactoferrin anticancer activity: from yeast to human cells 2019
- Yeast as a biotechnological factory 2019
- The role of zinc in acetic acid-induced cell death in yeast 2019
- Uncovering the role of vacuolar membrane proteins On Pep4P translocation/vacuolar membrane permeabilization during acetic acid-induced cell death 2019
- Yeast cells expressing human Bax as a tool to study its activation and regulation 2019
- How does the milk protein lactoferrin bind to V-ATPase? 2018
- Studying the effect of bovine milk lactoferrin on the plasma membrane of yeast and human cells 2018
- The highly metastatic prostate cancer PC-3 and osteosarcoma MG-63 cell lines are sensitive to bovine lactoferrin 2018
- Uncovering the role of vacuolar membrane proteins in acetic acid-induced cell death 2018
- Yeast Saccharomyces cerevisiae as a model organism to exploit the regulation of the human pro-apoptotic protein Bax 2018
- How can a milk protein selectively kill cancer cells? Mechanisms underlying lactoferrin-induced apoptosis 2018
- Lactoferrin perturbs intracellular trafficking in yeast and highly metastatic cancer cells 2018
- Role of vacuolar membrane proteins in acetic acid-induced cell death 2018
- Yeast as a cell model to study the human pro-apoptotic protein Bax 2018
- Exploring a novel effec of lactoferrin on the plasma membrane towards the elucidation of the mechanisms of action: from yeast to human cells 2018
- Exploring a novel effec of lactoferrin on the plasma membrane towards the elucidation of the mechanisms of action: from yeast to human cells 2017
- Mitochondrial ROS accumulation sensitizes colorectal cancer cells to acetate and Cathepsin D inhibitors combination therapy 2017
- Insights on the Molecular Mechanisms Underlying the Anticancer Activity of Lactoferrin in Highly Metastatic Cancer Cell Lines 2016
- Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemal V-H+-ATPase 2016
- Yeast as a tool to identify novel kinases involved in regulation of Bax 2015
- Lactoferrin selectively triggers apoptosis in highly metastatic breast cancer cells through inhibition of plasmalemal V-H+-ATPase 2015
- Yeast as a system model to characterize Bax regulation by individual kinases 2015
- An in vitro approach towards the elucidation of the mechanisms of action of lactoferrin 2014
- Functional characterization of mitochondrial suspensions by flow cytometry towards the screening of mitochondrial drug targets 2014
- Search for mechanisms underlying the anti-tumoral activity of lactoferrin 2014
- Human lactoferrin triggers a caspase- and mitochondrial-dependent programmed cell death in Saccharomyces cerevisiae 2014
- Mitochondria involvement in human lactoferrin-induced programmed cell death in Saccharomyces cerevisiae 2014
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teses
- Novel insights on the interaction of lactoferrin with proton pumping ATPases towards understanding of its antifungal and anticancer activities 2021
- Molecular mechanism underlying the anti-tumoral activity of lactoferrin 2014
- Analysis of the effect of exposing normal cells of Felis catus and Rattus norvegicus to the chemotherapeutic agent 5-azacytidine in the sequences of satellite DNA major 2012