publicações selecionadas
-
artigo académico
- The chick chorioallantoic membrane assay as an in vivo model for colon tumor analysis with optical coherence tomography. Expert Systems with Applications. 2024
- Antibiotic resistance: Assessing knowledge and misconceptions among Portuguese students and science teachers. Biochemistry and Molecular Biology Education. 2024
- Correction to “Machine Learning-Assisted Optimization of Drug Combinations in Zeolite-Based Delivery Systems for Melanoma Therapy”. ACS Applied Materials and Interfaces. 2024
- Machine Learning-Assisted Optimization of Drug Combinations in Zeolite-Based Delivery Systems for Melanoma Therapy. ACS Applied Materials and Interfaces. 2024
- Preliminary evaluation of zeolite-based platforms as potential dual drug delivery systems against microbial infections in the tumor microenvironment. Microporous and Mesoporous Materials. 2024
- Effects of Lactate Transport Inhibition by AZD3965 in Muscle-Invasive Urothelial Bladder Cancer. Pharmaceutics. 2023
- Extracellular Matrix Collagen I Differentially Regulates the Metabolic Plasticity of Pancreatic Ductal Adenocarcinoma Parenchymal Cell and Cancer Stem Cell. Cancers. 2023
- Immunoexpression profile of hypoxia-inducible factor (HIF) targets in potentially malignant and malignant oral lesions: a pilot study. Journal of Applied Oral Science. 2023
- Targeting monocarboxylate transporters (MCTs) in cancer: How close are we to the clinics?. Seminars in Cancer Biology. 2023
- Prognostic Value of Monocarboxylate Transporter 1 Overexpression in Cancer: A Systematic Review. International Journal of Molecular Sciences. 2023
- Clinical and Prognostic Impact of the Warburg Effect in Esophageal Carcinoma: Monocarboxylate Transporters as Candidates for Therapeutic Targeting. Pathobiology. 2023
- Selective cytotoxicity of Portuguese propolis ethyl acetate and butanol fractions towards renal cancer cells. Biomolecules. 2022
- Imidazolylpyrrolone-Based Small Molecules as Anticancer Agents for Renal Cell Carcinoma. Chemistry - A European Journal. 2022
- Glioblastoma Vasculature: From its Critical Role in Tumor Survival to Relevant in Vitro Modelling. Frontiers in Drug Delivery. 2022
- Renal cell carcinoma therapy: Current and new drug candidates. Drug Discovery Today. 2022
- Bringing vascularization into glioblastoma in vitro models. Trends in Molecular Medicine. 2021
- Modulating chitosan-PLGA nanoparticle properties to design a co-delivery platform for glioblastoma therapy intended for nose-to-brain route. Drug Delivery and Translational Research. 2020
- In vivo efficacy studies of chromene-based compounds in triple-negative breast cancer: A systematic review. European Journal of Pharmacology. 2020
- In vitro Evaluation of ASCs and HUVECs Co-cultures in 3D Biodegradable Hydrogels on Neurite Outgrowth and Vascular Organization. Frontiers in Cell and Developmental Biology. 2020
- IL-17A and IL-17F orchestrate macrophages to promote lung cancer. Cellular Oncology. 2020
- Lactate Beyond a Waste Metabolite: Metabolic Affairs and Signaling in Malignancy. Frontiers in Oncology. 2020
- Competitive glucose metabolism as a target to boost bladder cancer immunotherapy. Nature Reviews Urology. 2020
- 10.1038/s41585-019-0263-6. Nature Reviews Urology. 2020
- A novel strategy for glioblastoma treatment combining alpha-cyano-4-hydroxycinnamic acid with cetuximab using nanotechnology-based delivery systems. Drug Delivery and Translational Research. 2020
- Gene Disruption Using Zinc Finger Nuclease Technology. Methods in Molecular Biology. 2014
- How to decipher a microbial puzzle on microbial control : hands on. Online International Interdisciplinary Research Journal. 2014
- Monocarboxylate Transporters as Targets and Mediators in Cancer Therapy Response. Histology and Histopathology. 2014
- A Hospital Based Cohort Study of Colorectal Cancer Cases Treated at Braga Hospital, Northern Portugal. Journal of Gastrointestinal & Digestive System. 2013
- Lactate-Induced IL-8 Pathway in Endothelial Cells--Letter. Cancer Research. 2012
- Lymphatic Vessel Density in the Normal-Looking Columnar Epithelium Adjacent to and Distant from Prostatic Intraepithelial Neoplasia and Prostate Cancer Assessed in Whole-Mount Sections. Analytical and Quantitative Cytology and Histology. 2009
- Monocarboxylate transporter expression correlates with CD147 and HIF-1 alpha in gastric cancermonocarboxylate transporter expression correlates with CD147 and HIF-1 alpha in gastric cancer. Virchows Archiv. 2008
- Altered expression of monocarboxylate transporters 1, 2 and 4 in colorectal carcinomas. Virchows Archiv. 2007
-
artigo de conferência
- Exosome-mediated MEK1 silencing is a promising approach against triple negative breast cancer regression 2022
- Cellular delivery of CRISPR/Cas9 plasmid using multivalent cationic liposomes 2021
- Dual nanomaterial systems aiming antimicrobial activity and cancer treatment 2018
- Dual nanomaterial systems aiming antimicrobial activity and cancer treatment. 2018
- Enhancing 5-FU activity in colorectal carcinoma-derived cell lines: combination with monocarboxylate transporter inhibitors and encapsulation into zeolites 2012
- Zeolites: promising candidates for drug delivery systems (DDSs) 2012
- DNA damage prevention and signaling pathway regulation by sage in a colon cancer model 2011
- Diet and colon cancer - modulation of signaling pathways and DNA damage prevention 2011
- Monocarboxylate transporters - new molecular targets for colorectal carcinoma? 2011
- Monocarboxylate transporters as new attractive targets for colorectal carcinoma therapy 2011
- Monocarboxylate transporters: new molecular targets for colorectal carcinoma 2011
- Search for portuguese propolis antimicrobial activity in a wide range of microorganisms 2011
-
artigo de revista
- Optimization of iron-ZIF-8 catalysts for degradation of tartrazine in water by Fenton-like reaction. Chemosphere. 2023
- Phenolic Compounds Contribution to Portuguese Propolis Anti-Melanoma Activity. Biomolecules. 2023
- Glucose Metabolism Reprogramming in Bladder Cancer: Hexokinase 2 (HK2) as Prognostic Biomarker and Target for Bladder Cancer Therapy. Cancers. 2023
- Targeting Lysosomes in Colorectal Cancer: Exploring the Anticancer Activity of a New Benzo[a]phenoxazine Derivative. International Journal of Molecular Sciences. 2022
- 3-Bromopyruvate Suppresses the Malignant Phenotype of Vemurafenib-Resistant Melanoma Cells. International Journal of Molecular Sciences. 2022
- Microbiota-Derived Short-Chain Fatty Acids: New Road in Colorectal Cancer Therapy. Pharmaceutics. 2022
- Cytoskeleton disruption by the metabolic inhibitor 3-bromopyruvate: implications in cancer therapy. Medical Oncology. 2022
- Selective Cytotoxicity of Portuguese Propolis Ethyl Acetate Fraction towards Renal Cancer Cells. Biomolecules. 2022
- Portuguese Propolis Antitumoral Activity in Melanoma Involves ROS Production and Induction of Apoptosis. Biomolecules. 2022
- In Vitro CRISPR/Cas9 Transfection and Gene-Editing Mediated by Multivalent Cationic Liposome-DNA Complexes. Pharmaceutics. 2022
- Magnetic Solid Nanoparticles and Their Counterparts: Recent Advances towards Cancer Theranostics. Pharmaceutics. 2022
- Colon microbiota modulation by dairy-derived diet: new strategy for prevention and treatment of colorectal cancer. Food Bioscience. 2022
- In Vivo Anticancer Activity of AZD3965: A Systematic Review. Biomolecules. 2021
- MCT1 Is a New Prognostic Biomarker and Its Therapeutic Inhibition Boosts Response to Temozolomide in Human Glioblastoma. Cancers. 2021
- Cancer Cells’ Metabolism Dynamics in Renal Cell Carcinoma Patients’ Outcome: Influence of GLUT-1-Related hsa-miR-144 and hsa-miR-186. Cancers. 2021
- Nestin Expression Is Associated with Relapses in Head and Neck Lesions. Diagnostics. 2021
- Disruption of pH Dynamics Suppresses Proliferation and Potentiates Doxorubicin Cytotoxicity in Breast Cancer Cells. Pharmaceutics. 2021
- Surface functionalization of zeolite-based drug delivery systems enhances their antitumoral activity in vivo. Journal of Nanoparticle Research. 2021
- The Role of Diet Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications. Current Medicinal Chemistry. 2020
- Unravelling the anticancer potential of functionalized chromeno[2,3-b]pyridines for breast cancer treatment. Bioorganic Chemistry. 2020
- Microbes and Cancer: Friends or Faux?. International Journal of Molecular Sciences. 2020
- Immunity, hypoxia, and metabolism–the ménage à trois of cancer: Implications for immunotherapy. Physiological Reviews. 2020
- Fucoidan from Fucus vesiculosus inhibits new blood vessel formation and breast tumor growth in vivo. Carbohydrate Polymers. 2019
- Magnetoliposomes Containing Calcium Ferrite Nanoparticles for Applications in Breast Cancer Therapy. Pharmaceutics. 2019
- Direct actions of adiponectin on changes in reproductive, metabolic, and anti-oxidative enzymes status in the testis of adult mice. General and Comparative Endocrinology. 2019
- Clinical significance of metabolism-related biomarkers in non-Hodgkin lymphoma - MCT1 as potential target in diffuse large B cell lymphoma. Cellular Oncology. 2019
- Rational Identification of a Colorectal Cancer Targeting Peptide through Phage Display. Acta Cytologica. 2019
-
Photodynamic Therapy at Low-Light Fluence Rate:
in vitro Assays on Colon Cancer Cells. IEEE Journal of Selected Topics in Quantum Electronics. 2019 - Role of adiponectin as a modulator of testicular function during aging in mice. Biochimica et Biophysica Acta (BBA). Molecular Basis of Disease. 2019
- Synthesis, characterization and in vitro validation of a magnetic zeolite nanocomposite with T2-MRI properties towards theranostic applications. Journal of Materials Chemistry B. 2019
- Synthesis, characterization and in vitro validation of a magnetic zeolite nanocomposite with T2-MRI properties towards theranostic applications. Journal of Materials Chemistry B. 2019
- Exploitation of New Chalcones and 4H-chromenes as Agents for Cancer Treatment. European Journal of Medicinal Chemistry. 2018
- Adenine Derivatives: Promising Candidates for Breast Cancer Treatment. European Journal of Organic Chemistry. 2018
- Bioenergetic modulators hamper cancer cell viability and enhance response to chemotherapy. Journal of Cellular and Molecular Medicine. 2018
- The clinicopathological significance of monocarboxylate transporters in testicular germ cell tumors. Oncotarget. 2018
- Internalization studies on zeolite nanoparticles using human cells. Journal of Materials Chemistry B. 2018
- Monocarboxylate transporter 1 is a key player in glioma-endothelial cell crosstalk. Molecular Carcinogenesis. 2017
- Metabolic alterations underlying Bevacizumab therapy in glioblastoma cells. Oncotarget. 2017
- Impact of mesenchymal stem cells' secretome on glioblastoma pathophysiology. Journal of Translational Medicine. 2017
- Alginate hydrogel improves anti-angiogenic bevacizumab activity in cancer therapy. European Journal of Pharmaceutics and Biopharmaceutics. 2017
- Value of pH regulators in the diagnosis, prognosis and treatment of cancer. Seminars in Cancer Biology. 2017
- Comparison of different silica microporous structures as drug delivery systems for in vitro models of solid tumors. Nanoscale. 2017
- GLUT1 expression in pediatric adrenocortical tumors: A promising candidate to predict clinical behavior. Oncotarget. 2017
- HER Family Receptors are Important Theranostic Biomarkers for Cervical Cancer: Blocking Glucose Metabolism Enhances the Therapeutic Effect of HER Inhibitors. Theranostics. 2017
- The expression of monocarboxylate transporters in thyroid carcinoma can be associated with the morphological features of BRAF V600E mutation. Endocrine. 2016
- Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas. Oncotarget. 2016
- Absence of microsatellite instability and BRAF (V600E) mutation in testicular germ cell tumors.. Andrology. 2016
- Metabolic coupling in urothelial bladder cancer compartments and its correlation to tumor aggressiveness. Cell Cycle. 2016
- Metabolic coupling in urothelial bladder cancer compartments and its correlation to tumor aggressiveness. Cell Cycle. 2016
- Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications. Oncotarget. 2016
- Prognostic significance of monocarboxylate transporter expression in oral cavity tumors. Cell Cycle. 2016
- Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis. BMC Cancer. 2016
- The anticancer agent 3-bromopyruvate: a simple but powerful molecule taken from the lab to the bedside. Journal of Bioenergetics and Biomembranes. 2016
- The metabolic microenvironment of melanomas: Prognostic value of MCT1 and MCT4. Cell Cycle. 2016
- Colon Cancer Chemoprevention by Sage Tea Drinking: Decreased DNA Damage and Cell Proliferation. Phytotherapy Research. 2015
- Lactate transporters and pH regulation: potential therapeutic targets in glioblastomas.. Current Cancer Drug Targets. 2015
- Hotspot TERT promoter mutations are rare events in testicular germ cell tumors.. Tumor Biology. 2015
- Glucose Addiction in Cancer Therapy: Advances and Drawbacks.. Current Drug Metabolism. 2015
- Glucose Addiction in Cancer Therapy: Advances and Drawbacks.. Current Drug Metabolism. 2015
- A glycolytic phenotype is associated with prostate cancer progression and aggressiveness: a role for monocarboxylate transporters as metabolic targets for therapy.. Journal of Pathology. 2015
- Monocarboxylate transport inhibition potentiates the cytotoxic effect of 5-fluorouracil in colorectal cancer cells. Cancer Letters. 2015
- Cathepsin D protects colorectal cancer cells from acetate-induced apoptosis through autophagy-independent degradation of damaged mitochondria. Cell Death and Differentiation. 2015
- Targeting lactate transport suppresses in vivo breast tumour growth. Oncotarget. 2015
- Micro- and Mesoporous Structures as Drug Delivery Carriers for Salicylic Acid. Journal of Physical Chemistry C. 2015
- Localization of MCT2 at peroxisomes is associated with malignant transformation in prostate cancer. Journal of Cellular and Molecular Medicine. 2015
- CD147 and MCT1 - potential partners in bladder cancer aggressiveness and cisplatin resistance. Molecular Carcinogenesis. 2015
- Disruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 status. Oncotarget. 2015
- Evolving hallmarks in urothelial bladder cancer: unveiling potential biomarkers. Acta Urológica Portuguesa. 2015
- Impact of an educational hands-on project on the antimicrobial, antitumor and anti-inflammatory properties of plants on Portuguese students' awareness, knowledge, and competences. Healthcare. 2015
- In vitro and in vivo studies of temozolomide loading in zeolite structures as drug delivery systems for glioblastoma. Nanoscale. 2015
- Metabolic reprogramming: A new relevant pathway in adult adrenocortical tumors. Oncotarget. 2015
- Propolis: A Complex Natural Product with a Plethora of Biological Activities That Can Be Explored for Drug Development. Evidence-based Complementary and Alternative Medicine. 2015
- Reprogramming energy metabolism and inducing angiogenesis: Co-expression of monocarboxylate transporters with VEGF family members in cervical adenocarcinomas. BMC Cancer. 2015
- SMYD3 contributes to a more aggressive phenotype of prostate cancer and targets Cyclin D2 through H4K20me3. Oncotarget. 2015
- The cytotoxicity of 3-bromopyruvate in breast cancer cells depends on extracellular pH. Biochemical Journal. 2015
- Urothelial bladder cancer progression: lessons learned from the bench. Journal of Cancer Metastasis and Treatment. 2014
- Antitumoural and antiangiogenic activity of Portuguese propolis in in vitro and in vivo models. Journal of Functional Foods. 2014
- Lactate Transporters in the Context of Prostate Cancer Metabolism: What Do We Know?. International Journal of Molecular Sciences. 2014
- T-box Transcription Factor Brachyury Is Associated with Prostate Cancer Progression and Aggressiveness. Clinical Cancer Research. 2014
- How to decipher a microbial puzzle on microbial control: hands on. Online International Interdisciplinary Research Journal. 2014
- A lactate shuttle system between tumour and stromal cells is associated with poor prognosis in prostate cancer. BMC Cancer. 2014
- Characterization of monocarboxylate transporter activity in hepatocellular carcinoma. World Journal of Gastroenterology. 2014
- Characterization of monocarboxylate transporters (MCTs) expression in soft tissue sarcomas: distinct prognostic impact of MCT1 sub-cellular localization. Journal of Translational Medicine. 2014
- Lactate transporters and vascular factors in HPV-induced squamous cell carcinoma of the uterine cervix. BMC Cancer. 2014
- Monocarboxylate transporters as targets and mediators in cancer therapy response. Histology and Histopathology. 2014
- The basal epithelial marker P-cadherin associates with breast cancer cell populations harboring a glycolytic and acid-resistant phenotype. BMC Cancer. 2014
- Potentiation of 5-fluorouracil encapsulated in zeolites as drug delivery systems for in vitro models of colorectal carcinoma. Colloids and Surfaces B: Biointerfaces. 2013
- Differential sensitivities to lactate transport inhibitors of breast cancer cell lines. Endocrine-Related Cancer. 2013
- Portuguese propolis disturbs glycolytic metabolism of human colorectal cancer in vitro. BMC Complementary and Alternative Medicine. 2013
- Assessing the Impact of a School Intervention to Promote Students’ Knowledge and Practices on Correct Antibiotic Use. Healthcare. 2013
- A hospital based cohort study of colorectal cancer cases treated at Braga Hospital, Northern Portugal. Journal Gastrointestinal & Digestive System. 2013
- Cancer cell bioenergetics and pH regulation influence breast cancer cell resistance to paclitaxel and doxorubicin. Journal of Bioenergetics and Biomembranes. 2013
- Loss of caveolin-1 and gain of MCT4 expression in the tumor stroma Key events in the progression from an in situ to an invasive breast carcinoma. Cell Cycle. 2013
- Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets. Neuro-Oncology. 2013
- The Monocarboxylate Transporter Inhibitor a-Cyano-4-Hydroxycinnamic Acid Disrupts Rat Lung Branching. Cellular Physiology and Biochemistry. 2013
- Zeolite Structures Loading with an Anticancer Compound As Drug Delivery Systems. Journal of Physical Chemistry C. 2012
- Monocarboxylate transporter 2 (MCT2) as putative biomarker in prostate cancer. Prostate. 2012
- CD147 immunohistochemistry discriminates between reactive mesothelial cells and malignant mesothelioma. Diagnostic Cytopathology. 2012
- 3-bromopyruvate, butyrate, monocarboxylate transporters, warburg effect. Journal of Bioenergetics and Biomembranes. 2012
- Role of monocarboxylate transporters in human cancers : state of the art. Journal of Bioenergetics and Biomembranes. 2012
- Co-expression of monocarboxylate transporter 1 (MCT1) and its chaperone (CD147) is associated with low survival in patients with gastrointestinal stromal tumors (GISTs). Journal of Bioenergetics and Biomembranes. 2012
- Encapsulation of a-cyano-4-hydroxycinnamic acid into a NaY zeolite. Journal of Materials Science. 2011
- GLUT1 and CAIX expression profiles in breast cancer correlate with adverse prognostic factors and MCT1 overexpression. Histology and Histopathology. 2011
- CD147 overexpression allows an accurate discrimination of bladder cancer patients' prognosis. Ejso. 2011
- Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer.. BMC Cancer. 2011
- Role of endoglin and VEGF family expression in colorectal cancer prognosis and anti-angiogenic therapies. World Journal of Clinical Oncology. 2011
- The selective COX-2 inhibitor Etoricoxib reduces acute inflammatory markers in a model of neurogenic laryngitis but loses its efficacy with prolonged treatment. Inflammation Research. 2010
- Monocarboxylate transporter 1 is up-regulated in basal-like breast carcinoma.. Histopathology. 2010
- Expression of Monocarboxylate Transporters 1, 2, and 4 in Human Tumours and Their Association with CD147 and CD44. Biomed Research International. 2010
- Portuguese students' knowledge of antibiotics: a cross-sectional study of secondary school and university students in Braga. BMC Public Health. 2009
- Molecular characterization of EGFR, PDGFRA and VEGFR2 in cervical adenosquamous carcinoma. BMC Cancer. 2009
- Monocarboxylate transporters 1 and 4 are associated with CD147 in cervical carcinoma. Disease Markers. 2009
- The prognostic value of CD147/EMMPRIN is associated with monocarboxylate transporter 1 co-expression in gastric cancer. European Journal of Cancer. 2009
- Induction of COX-2 expression by acrolein in the rat model of hemorrhagic cystitis.. Experimental and Toxicologic Pathology. 2008
- Increased expression of monocarboxylate transporters 1, 2, and 4 in colorectal carcinomas. International Journal of Gynecological Pathology. 2008
- A New Model of Laryngitis: Neuropeptide, Cyclooxygenase, and Cytokine Profile. Laryngoscope. 2008
- Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats. Journal of Cancer Research and Clinical Oncology. 2008
- Peritumoural, but not intratumoural, lymphatic vessel density and invasion correlate with colorectal carcinoma poor-outcome markers. Virchows Archiv. 2008
- Immunohistochemical expression and distribution of VEGFR-3 in malignant mesothelioma. Diagnostic Cytopathology. 2007
- Lymphatic vessel density and epithelial D2-40 immunoreactivity in pre-invasive and invasive lesions of the uterine cervix. Gynecologic Oncology. 2007
- Cyclooxygenase-2 and epidermal growth factor receptor expressions in different histological subtypes of cervical carcinomas. International Journal of Gynecological Pathology. 2007
- Immunohistochemical expression of VEGF-A and its ligands in non-neoplastic lesions of the breast sampling-assisted by dynamic angiothermography. Oncology Reports. 2007
- Immunohistochemical expression of VEGF-A and its ligands in non-neoplastic lesions of the breast sampling-assisted by dynamic angiothermography. Oncology Reports. 2007
- Functional Purification of the Monocarboxylate Transporter of the Yeast Candida utilis. Biotechnology Letters. 2006
- EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. Journal of Pathology. 2006
- Functional expression of the lactate permease Jen1p of Saccharomyces cerevisiae in Pichia pastoris. Biochemical Journal. 2003
-
capítulo de livro
- 3D culture systems as models for solid tumors and cancer metabolism 2020
- Angiogenesis and Chromene-based Antiangiogenic Therapeutic Agents 2020
- Lactate and lactate transporters as key players in the maintenance of the Warburg effect 2020
- New horizons on pH regulators as cancer biomarkers and targets for pharmacological intervention 2020
- Angiogenesis and chromene-based antiangiogenic therapeutic agents 2019
- Antitumor properties of honeybee plant-derived products: honey, propolis and pollen 2016
- Brain Tumor Metabolism — Unraveling Its Role in Finding New Therapeutic Targets 2015
- Targeting Metabolic Reprogramming as an Anti- Cancer Strategy: Aiming at Monocarboxylate Transporters 2015
-
documento
- Synthesis of imidazo-pyridines/diazepines and evaluation of their anticancer potential in renal cell carcinoma cell lines 2023
- New imidazole based scaffolds for the treatment of renal cell carcinoma 2023
- Effects of lactate transport inhibition by AZD3965 in muscle-invasive urothelial bladder cancer 2023
- New imidazole derivatives as anticancer agents for the treatment of renal cell carcinoma 2023
- Treatment of triple-negative breast cancer through externally triggered target-less drug carriers 2023
- Prognostic Value of Monocarboxylate Transporter 1 Overexpression in Cancer: A Systematic Review 2023
- Cellular delivery of CRISPR/Cas9 plasmid using multivalent cationic liposomes 2022
- Chromen[2,3-b]pyridines: synthesis and evaluation of the anticancer potential for breast cancer treatment 2022
- Farmacologia pré-clínica do inibidor do transportador de monocarboxilatos 1, AZD3965, no cancro da bexiga 2022
- Hexokinase II (HKII) as prognostic biomarker and target for bladder cancer therapy 2022
- GPR81 in Bladder Cancer - Functional Insights 2022
- Pre-clinical pharmacology of the monocarboxylate transporter 1 inhibitor AZD3965 in bladder cancer 2022
- Exosome-mediated MEK1 silencing is a promising approach against triple negative breast cancer regression 2022
- Exosome-mediated MEK1 silencing is a promising approach against triple negative breast cancer regression 2022
- Non-viral delivery of CRISPR/Cas9 DNA for gene editing via multivalent cationic liposome system 2022
- Non-viral delivery of CRISR/Cas9 for gene editing via multivalent cationic liposome system 2022
- Cellular delivery of CRISPR/Cas9 plasmid using multivalent cationic liposomes 2021
- Targeting oncogenic microRNAs in triple negative breast cancer using a CRISPR/Cas9-based approach 2021
- Assessing the Antitumoral Activity of Portuguese Propolis Fractions in Melanoma 2021
- In vitro validation of a new magnetic solid lipid nanoformulation against Triple-Negative Breast Cancer 2021
- Exossomas modificados para o desenvolvimento de novas terapias para cancro de mama triplo negativo 2021
- Validation of a new nanoformulation for the diagnostic and treatment of triple-negative breast cancer 2021
- Validação de uma nova nanoformulação direcionada para o diagnóstico e tratamento do cancro da mama triplo-negativo 2021
- New chromene derivatives: overcoming renal cell carcinoma drug resistance 2021
- A new therapeutic option for triple negative breast cancer 2021
- Hexokinase II (HKII) is a prognostic biomarker for bladder cancer patients: Antitumoral activity of the HKII inhibitor 2-deoxy-D-glucose 2021
- Novel therapy for renal cell carcinoma: overcoming drug resistance 2021
- Engineered exosome-mediated delivery of RNAi therapeutics towards triple negative breast cancer therapy 2021
- Engineered exosome-mediated delivery of RNAi therapeutics towards triple negative breast cancer therapy 2021
- Targeting glycolytic metabolism as a therapeutic strategy for Acute Myeloid Leukemia 2021
- In vitro validation of new theranostic nanoformulation against Triple-negative breast cancer 2021
- Upregulation of Hexokinase II (HKII) impacts survival of bladder cancer patients: Effects of HKII inhibition by 2-deoxy-D-glucose 2021
- In vitro validation of a new magnetic formulation against Trile-negative breast cancer 2021
- In vitro validation of a new magnetic formulation against Triple-Negative Breast Cancer 2021
- In vitro validation of a new theranostic nanoformulation against Triple-Negative Breast Cancer 2021
- Renal anticancer activity of Portuguese propolis fractions and isolated compounds 2021
- Targeting oncogenic microRNAs in triple negative breast cancer using a CRISPR/Cas9-based approach 2020
- New substituted 3,5-dihydro-4H-chromeno [2,3-d] pyrimidin-4-one: a promising strategy for breast cancer treatment 2020
- New substituted 3,5-dihydro-4H-chromeno [2,3-d] pyrimidin4-one: a promising strategy for breast cancer treatment 2020
- Metabolic remodelling in cisplatin-resistant bladder cancer 2020
- The role of microbiota-derived short chain fatty acids in the modulation of colorectal cancer glycolytic metabolism and extracellular pH 2020
- 3-bromopyruvate boosts the effect of chemotherapy in acute myeloid leukemia by reducing cell antioxidant defense 2020
- Non-toxic concentrations of 3-bromopyruvate sensitize acute leukemia cells to chemotherapy by inducing oxidative stress 2020
- New chromene derivatives: unravelling the molecular mechanisms for breast cancer treatment 2019
- Disruption of cancer cell metabolism using targeted-drug delivery systems 2019
- Characterization of glycolytic metabolism of oesophageal carcinomas and evaluation of its potential as therapeutic target 2019
- Cisplatin-resistant urothelial bladder cancer cells undergo metabolic reprogramming 2019
- Chromene derivatives: a new strategy to overcome renal cancer resistance 2019
- Exploitation of novel chromene derivatives for breast cancer treatment 2019
- Synthesis and biological activity of new anticancer agents for breast cancer treatment 2019
- New chromene-based molecules for renal cell cancer therapy 2019
- New molecules based on chromene moiety as candidates for renal cell carcinoma therapy 2019
- New chromene derivatives: Unraveling the molecular mechanisms for breast cancer therapy 2019
- Chromene-based compounds as candidates for renal cell cancer treatment 2019
- In vitro and in vivo efficacy evaluation of drug delivery systems based on zeolites 2019
- Synthesis of functionalized chromeno[2,3-b]pyridines: promising agents for breast cancer treatment 2019
- Biological activity of novel targeted inhibitors for renal cell cancer therapy 2019
- Fucoidan impairs the formation of tubular-like structures in vitro and inhibits tumor growth in vivo. 2019
- In vitro and in vivo evaluation of new chromene derivatives as potent anticancer agents 2019
- Chromene-based molecules as targeted inhibitors for renal cell cancer therapy 2019
- 3-Bromopyruvate pre-treatment sensitizes MOLM13 and KG-1 cell lines to chemotherapy 2019
- New chromene-based molecules as microtubule destabilizers and pro-apoptotic agents in cancer 2018
- Chemical and biological characterization of chalcones and 4H-chromenes: exploitation as anticancer agents 2018
- Targeting cancer cell metabolism using targeted-drug delivery systems 2018
- Unraveling the anticancer molecular mechanisms of new chromene-based drugs 2018
- Discovery of chromene-based molecules as apoptosis-inducers by G2/M cell-arrest 2018
- Chromene-based drug candidates for cancer treatment 2018
- Dual nanomaterial systems aiming antimicrobial activity and cancer treatment 2018
- Dual nanomaterial systems aiming antimicrobial activity and cancer treatment. 2018
- Fucoidan impairs angiogenesis and tumor growth in vivo 2018
- Fucoidan inhibits new blood vessels formation in a tumor microenvironment 2018
- Portuguese Propolis: A source of valuable bioactivities. Journal of Apitherapy and Nature (JAN). 2018
- New chromene-based drug candidates for cancer treatment 2017
- Understanding the cellular metabolic reprogramming associated with bevacizumab therapy in glioblastoma 2017
- Chromene derivatives as anticancer agents: synthesis and biological evaluation 2016
- Targeting glycolysis in acute myeloid leukemia: therapeutic applications 2016
- The metabolic coupling among urothelial bladder cancer compartments predicts tumour aggressiveness and chemoresistance 2015
- Novel synthetic molecules bioinspired in natural phenolic compounds for anticancer drug discovery 2014
- Análise dos mecanismos de actividade biológica do própolis do Pereiro 2014
- Caracterização da actividade antitumoral e angiogénica do própolis português usando modelos in vitro e in vivo 2014
- CD147 and MCT1: Potential partners in bladder cancer aggressiveness and cisplatin resistance 2013
- Exploiting monocarboxylate transporters as newmolecular targets for colorectal carcinomatherapy. ets for colorectal carcinoma therapy 2013
- Enhancing 5-FU activity in colorectal carcinoma-derived cell lines: combination with monocarboxylate transporter inhibitors and encapsulation into zeolites. European Journal of Cancer. 2012
- Zeolites: Promising candidates for drug delivery systems (DDSs) 2012
- Search for portuguese propolis antimicrobial activity in a wide range of microorganisms 2011
- Diet and colon cancer - modulation of signaling pathways and DNA damage prevention 2011
- Bioactivities of Portuguese Propolis 2011
- DNA damage prevention and signaling pathway regulation by sage in a colon cancer model 2011
- Monocarboxylate transporters - new molecular targets for colorectal carcinoma? 2011
- CD147 overexpression allows an accurate discrimination of bladder cancer patients' prognosis 2011
- Monocarboxylate transporters as new attractive targets for colorectal carcinoma therapy 2011
- Monocarboxylate transporters: new molecular targets for colorectal carcinoma 2011
- Functional expression of the lactate permease Jen1p of Saccharomyces cerevisiae in Pichia pastoris 2003
-
livro
-
poster de conferência
- In silico prediction and design of CRISPR sgRNAs targeting miR-155 for TNBC treatment 2020
- CRISPR/Cas9-mediated knockout of miR-155 for Triple Negative Breast Cancer treatment 2020
- 3-bromopyruvate boosts the effect of chemotherapy in acute myeloid leukemia by reducing cell antioxidant defense 2020
- Non-toxic concentrations of 3-bromopyruvate sensitize acute leukemia cells to chemotherapy by inducing oxidative stress 2020
- 3-Bromopyruvate pre-treatment sensitizes MOLM13 and KG-1 cell lines to chemotherapy 2019
- Targeting oncogenic microRNAs in triple negative breast cancer using CRISPR/cas9 approach 2018