publicações selecionadas
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artigo académico
- A versatile yeast model to screen for pesticides as risk factors for synucleinopathies. Chemosphere. 2024
- Lactate induces cisplatin resistance in S. cerevisiae through a Rad4p-dependent process. Oxidative Medicine and Cellular Longevity. 2020
- Cell wall dynamics modulate acetic acid-induced apoptotic cell death of Saccharomyces cerevisiae. Microbial Cell. 2014
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artigo de revista
- Acetic acid triggers cytochrome c release in yeast heterologously expressing human Bax. Apoptosis. 2022
- Saccharomyces cerevisiae Cells Lacking the Zinc Vacuolar Transporter Zrt3 Display Improved Ethanol Productivity in Lignocellulosic Hydrolysates. Journal of Fungi. 2022
- Regulation of Cell Death Induced by Acetic Acid in Yeasts. Frontiers in Cell and Developmental Biology. 2021
- Lactoferrin perturbs lipid rafts and requires integrity of Pma1p-lipid rafts association to exert its antifungal activity against Saccharomyces cerevisiae. International Journal of Biological Macromolecules. 2021
- The Role of Diet Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications. Current Medicinal Chemistry. 2020
- Lactate Induces Cisplatin Resistance in S. cerevisiae through a Rad4p-Dependent Process. Oxidative Medicine and Cellular Longevity. 2020
- Proteasome inhibition prevents cell death induced by the chemotherapeutic agent cisplatin downstream of DNA damage. DNA Repair. 2019
- Antibiotic free selection for the high level biosynthesis of a silk-elastin-like protein. Acta Cytologica. 2016
- VDAC regulates AAC-mediated apoptosis and cytochrome c release in yeast. Microbial Cell. 2016
- Ceramide signalling impinges on Sit4p and Hog1p to promote mitochondrial fission and mitophagy in Isc1p-deficient cells. Cellular Signalling. 2015
- Cathepsin D protects colorectal cancer cells from acetate-induced apoptosis through autophagy-independent degradation of damaged mitochondria. Cell Death and Differentiation. 2015
- Colorectal cancer-related mutant KRAS alleles function as positive regulators of autophagy. Oncotarget. 2015
- RAF-1 promotes survival of thyroid cancer cells harboring RET/PTC1 rearrangement independently of ERK activation. Molecular and Cellular Endocrinology. 2015
- Yeast as a tool to explore cathepsin D function. Microbial Cell. 2015
- C2-Phytoceramide Perturbs Lipid Rafts and Cell Integrity in Saccharomyces cerevisiae in a Sterol-Dependent Manner. Antibiotics. 2013
- Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D release. Cell Death and Differentiation. 2013
- Genome-wide identification of genes involved in the positive and negative regulation of acetic acid-induced programmed cell death in Saccharomyces cerevisiae. BMC Genomics. 2013
- Modulation of Mitochondrial Outer Membrane Permeabilization and Apoptosis by Ceramide Metabolism. Antibiotics. 2012
- Efficient nuclear transport of structurally disturbed cargo: mutations in a cargo protein switch its cognate karyopherin.. Antibiotics. 2011
- The impact of acetate metabolism on yeast fermentative performance and wine quality: reduction of volatile acidity of grape musts and wines. Applied Microbiology and Biotechnology. 2011
- Vacuole-mitochondrial cross-talk during apoptosis in yeast: A model for understanding lysosome-mitochondria-mediated apoptosis in mammals. Biochemical SocIETy Transactions. 2011
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capítulo de livro
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documento
- Novas estirpes e metodologias para ultrapassar desafios emergentes na produção de vinho 2023
- Manipulation of Torulaspora delbrueckii glucose transport for improved growth and fermentative performance. Manuscript in Preparation 2023
- Characterization of the repertoire of hexose transportes in Torulaspora delbrueckii 2022
- Manipulation of glucose transport for improved growth and fermentation of Torulaspora delbrueckii 2022
- Integrated biochemical and computational approach reveals novel mechanisms underlying the antifungal activity of the milk-derived lactoferrin protein 2021
- Acetic acid as a trigger to activate human Bax heterologously expressed in yeast 2021
- Carbon source affects sensitivity to the anti-cancer agent cisplatin in Saccharomyces cerevisiae 2019
- The impact of zinc in yeast cell death induced by acetic acid 2019
- Which molecular mechanisms are involved in the antifungal activity of the milk-derived protein lactoferrin? 2019
- The role of membrane lipid domains on lactoferrin anticancer activity: from yeast to human cells 2019
- Uncovering the role of acetate in the prevention of colorectal cancer induced by food contaminants. 2019
- The role of zinc in acetic acid-induced cell death in yeast 2019
- Uncovering the role of vacuolar membrane proteins On Pep4P translocation/vacuolar membrane permeabilization during acetic acid-induced cell death 2019
- Yeast cells expressing human Bax as a tool to study its activation and regulation 2019
- How carbon source affects the sensitivity to the anti-cancer agent cisplatin 2019
- How can a milk protein selectively kill cancer cells? Mechanisms underlying lactoferrin-induced apoptosis 2019
- Studying the effect of bovine milk lactoferrin on the plasma membrane of yeast and human cells 2018
- Uncovering the role of vacuolar membrane proteins in acetic acid-induced cell death 2018
- Yeast Saccharomyces cerevisiae as a model organism to exploit the regulation of the human pro-apoptotic protein Bax 2018
- The effect of carbon source in the sensitivity to the anti-cancer agent cisplatin 2018
- How can a milk protein selectively kill cancer cells? Mechanisms underlying lactoferrin-induced apoptosis 2018
- Lactoferrin perturbs intracellular trafficking in yeast and highly metastatic cancer cells 2018
- Deciphering the mechanisms underlying bovine milk lactoferrin anticancer activity using yeast and cancer cell lines as complementary models 2018
- Role of vacuolar membrane proteins in acetic acid-induced cell death 2018
- Yeast as a cell model to study the human pro-apoptotic protein Bax 2018
- Saccharomyces cerevisiae as a model system to uncover target and off-target effects of fungicides of environmental concern 2018
- Exploring a novel effec of lactoferrin on the plasma membrane towards the elucidation of the mechanisms of action: from yeast to human cells 2018
- Exploring a novel effec of lactoferrin on the plasma membrane towards the elucidation of the mechanisms of action: from yeast to human cells 2017
- The role of metabolism in the sensitivity of S. cerevisiae to the anti-cancer agent cisplatin 2017
- Exploring a novel effect of lactoferrin on the plasma membrane towards the elucidation of the mechanisms of action: from yeast to human cells 2017
- Mitochondrial ROS accumulation sensitizes colorectal cancer cells to acetate and Cathepsin D inhibitors combination therapy 2017
- The role of metabolism in the sensitivity of S. cerevisiae to the anti-cancer agent cisplatin. 2016
- Yeast as a tool to identify novel kinases involved in regulation of Bax 2015
- Yeast as a system model to characterize Bax regulation by individual kinases 2015
- Cathepsin D is involved in the degradation of damaged mitochondria during acetate-induced apoptosis in colorectal cancer cells. 2015
- Cathepsin D protects colorectal cancer cells from acetate-induced apoptosis through autophagy-independent degradation of damaged mitochondria 2015
- Vacuole-mitochondrial crosstalk during apoptosis induced by acetic acid in yeast 2011
- Genome-wide identification of genes involved in the positive and negative regulation of acetic acid-induced cell death in saccharomyces cerevisiae 2011
- Role of C2-phytoceramide in mediating cell death in yeast 2011
- Characterization of cisplatin-induced cell death in S. cerevisiae 2011
- MAPK signaling pathways mediate acetic acid-induced cell death in saccharomyces cerevisiae 2011
- The involvement of sphingolipids in apoptosis induced by acetic acid in yeast 2011
- What yeast can tell us about how cells commit suicide? 2011
- Yeast as a model system to study mechanisms regulating cisplatin sensitivity and resistance 2011
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teses