publicações selecionadas
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artigo académico
- The Yeast Protein Kinase Sch9 Functions as a Central Nutrient-Responsive Hub That Calibrates Metabolic and Stress-Related Responses. Journal of Fungi. 2023
- Effects of Intermittent Fasting on Regulation of Metabolic Homeostasis: A Systematic Review and Meta-Analysis in Health and Metabolic-Related Disorders. Journal of Clinical Medicine. 2023
- Current and Emerging Techniques for Diagnosis and MRD Detection in AML: A Comprehensive Narrative Review. Cancers. 2023
- Innovative, integrative, and interactive in-class activity on metabolic regulation: Evaluating educational impacts. Biochemistry and Molecular Biology Education. 2021
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021
- Elucidating the mechanisms of action of parecoxib in the MG-63 osteosarcoma cell line. Anti-Cancer Drugs. 2020
- The antifungal plant defensin HsAFP1 induces autophagy, vacuolar dysfunction and cell cycle impairment in yeast. Biochimica et Biophysica Acta (BBA). Biomembranes. 2020
- Unravelling the anticancer potential of functionalized chromeno[2,3-b ] pyridines for breast cancer treatment. Bioorganic Chemistry. 2020
- Transcriptomic and chemogenomic analyses unveil the essential role of Com2-regulon in response and tolerance of Saccharomyces cerevisiae to stress induced by sulfur dioxide. Microbial Cell. 2019
- From Regulated Cell Death to Adaptive Stress Strategies: Convergence and Divergence in Eukaryotic Cells. Oxidative Medicine and Cellular Longevity. 2018
- New perspectives from South-Y-East, not all about death A report of the 12th lnternational Meeting on Yeast Apoptosis in Bari, Italy, May 14th-18th, 2017. Microbial Cell. 2018
- Chronic stress triggers tau pathology through autophagy inhibition and induction of stress granules. Journal of Neurochemistry. 2017
- The Role of Nitric Oxide Signalling in Yeast Stress Response and Cell Death. Handbook of Microbial Metabolism of Amino Acids. 2017
- Yeast on the corner of life and death decisions. Mechanisms of Ageing and Development. 2017
- The "stressed" autophagy: chronic stress exacerbates Tau pathology by blocking autophagy clearance system. Brain Structure and Function. 2016
- The Role of Autophagy on the Differentiation Potential of Adipose Stromal Cell Sheets under Normoxia vs Hypoxia. Tissue Engineering. Part C: Methods. 2015
- Longevity pathways and maintenance of the proteome: the role of autophagy and mitophagy during yeast ageing. Microbial Cell. 2014
- Yeast between life and death: a summary of the Ninth International Meeting on Yeast Apoptosis in Rome, Italy, 17–20 September 2012. Cell Death and Differentiation. 2013
- Yeast Stress, Aging, and Death. Oxidative Medicine and Cellular Longevity. 2013
- Cellular Models of Aging. Oxidative Medicine and Cellular Longevity. 2012
- Yeast as a platform to uncover ceramide-induced ancient cell death routines. Cell Cycle. 2012
- Overeating yeast display fatty acid-induced necrotic cell death. Cell Cycle. 2010
- Mismatches between the conceptual level of tests and faculty beliefs. Faseb Journal. 2009
- Neurodevelopmental delay in the Cln3(Delta ex7/8) mouse model for Batten disease. Genes, Brain and Behavior. 2009
- Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and apoptosis. Endocrinology. 2008
- Singular yeast cell morphology of Paracoccidioides brasiliensis is associated to virulence: down-regulation of the CDC42 homolog. The FEBS Journal. 2008
- Studying the role of nitric oxide in the pathological mechanism of Batten disease. The FEBS Journal. 2008
- Role of Isc1p in oxidative stress resistance and ageing in yeast. Chemistry and Physics of Lipids. 2006
- Saccharomyces cerevisiae commits to programmed cell death in response to hyperosmotic stress caused by glucose. Cytometry Part A. 2004
- Acetic acid induces a programmed cell death process in the food spoilage yeast. FEMS Yeast Research. 2003
- Acetic acid induces a programmed cell death process in the food spoilage yeast Zygosaccharomyces badii (vol 2, pg 91, 2003). FEMS Yeast Research. 2003
- Sphingolipid signalling in stress resistance and chronological life-span in Saccharomyces cerevisiae: the role of Isc1p. Yeast. 2003
- Assessment of mitochondrial membrane potential in yeast cell populations by flow cytometry. Microbiology. 2001
- Programmed cell death in Saccharomyces cerevisiae induced by acetic acid.. Yeast. 2001
- Saccharomyces cerevisiae commits to a programmed cell death process in response to acetic acid. Microbiology. 2001
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artigo de conferência
- The role of autophagy on the differentiation potential of adipose stromal cell sheets under normoxia vs hypoxia 2015
- Evaluation of the protective effect of Hypericum perforatum phenolics compounds, in the toxicity induced by heterologous expression of a-synuclein 2011
- Hypericum perforatum phenolics compounds: protective role in the toxicity induced by heterologous expression of a-synuclein 2011
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artigo de revista
- Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization. International Journal of Molecular Sciences. 2023
- Anti-Aging and Neuroprotective Properties of Grifola frondosa and Hericium erinaceus Extracts. Nutrients. 2022
- Functional Genetic Variants in ATG10 Are Associated with Acute Myeloid Leukemia. Cancers. 2021
- Polymorphisms within Autophagy-Related Genes Influence the Risk of Developing Colorectal Cancer: A Meta-Analysis of Four Large Cohorts. Cancers. 2021
- Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot. Biology. 2020
- Targeting Metabolic Reprogramming in Acute Myeloid Leukemia. Cells. 2019
- a-Synuclein toxicity in yeast and human cells is caused by cell cycle re-entry and autophagy degradation of ribonucleotide reductase 1. Aging Cell. 2019
- Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology. Cell Death and Differentiation. 2018
- Exploitation of New Chalcones and 4H-chromenes as Agents for Cancer Treatment. European Journal of Medicinal Chemistry. 2018
- Signalling mechanisms that regulate metabolic profile and autophagy of acute myeloid leukaemia cells. Journal of Cellular and Molecular Medicine. 2018
- Linking cellular proteostasis to yeast longevity. FEMS Yeast Research. 2018
- pH homeostasis links the nutrient sensing PKA/TORC1/Sch9 ménage-à-trois to stress tolerance and longevity. Microbial Cell. 2018
- Caloric restriction rescues yeast cells from alpha-synuclein toxicity through autophagic control of proteostasis. Aging-Us. 2018
- Guidelines and recommendations on yeast cell death nomenclature. Microbial Cell. 2018
- Lipocalin-2 regulates adult neurogenesis and contextual discriminative behaviours. Elife. 2018
- The sensitivity of the yeast, Saccharomyces cerevisiae, to acetic acid is influenced by DOM34 and RPL36A. Antibiotics. 2017
- Cell sheet engineering using the stromal vascular fraction of adipose tissue as a vascularization strategy. Acta Biomaterialia. 2017
- Caloric restriction alleviates alpha-synuclein toxicity in aged yeast cells by controlling the opposite roles of Tor1 and Sir2 on autophagy. Mechanisms of Ageing and Development. 2017
- Increasing the Fungicidal Action of Amphotericin B by Inhibiting the Nitric Oxide-Dependent Tolerance Pathway. Oxidative Medicine and Cellular Longevity. 2017
- Mitochondrial proteomics of the acetic acid - induced programmed cell death response in a highly tolerant Zygosaccharomyces bailii - derived hybrid strain. Microbial Cell. 2016
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016
- AMPK in Pathogens. EXS. 2016
- IL-17A Promotes Intracellular Growth of Mycobacterium by Inhibiting Apoptosis of Infected Macrophages. Frontiers in Immunology. 2015
- Sirtuins and Proteolytic Systems: Implications for Pathogenesis of Synucleinopathies. Biomolecules. 2015
- Bioresorbable ureteral stents from natural origin polymers. Journal of Biomedical Materials Research: Part B. 2015
- Proteolytic systems and AMP-activated protein kinase are critical targets of acute myeloid leukemia therapeutic approaches. Oncotarget. 2014
- Proteomic Analysis of the Action of the Mycobacterium ulcerans Toxin Mycolactone: Targeting Host Cells Cytoskeleton and Collagen. PLoS Neglected Tropical Diseases. 2014
- Reactive oxygen species, ageing and the hormesis police. FEMS Yeast Research. 2013
- Involvement of Yeast HSP90 Isoforms in Response to Stress and Cell Death Induced by Acetic Acid. Antibiotics. 2013
- DNA replication stress-induced loss of reproductive capacity inS. cerevisiaeand its inhibition by caloric restriction. Cell Cycle. 2013
- P. brasiliensis Virulence Is Affected by SconC, the Negative Regulator of Inorganic Sulfur Assimilation. Antibiotics. 2013
- SNCA (a-synuclein)-induced toxicity in yeast cells is dependent on Sir2-mediated mitophagy. Autophagy. 2012
- Functionality of the Paracoccidioides Mating a-Pheromone-Receptor System. Antibiotics. 2012
- Morphological heterogeneity of Paracoccidioides brasiliensis: Relevance of the Rho-like GTPase PbCDC42. Blood. 2012
- An alternative respiratory pathway on Candida krusei: implications on susceptibility profile and oxidative stress. FEMS Yeast Research. 2012
- The Fate of Acetic Acid during Glucose Co-Metabolism by the Spoilage Yeast Zygosaccharomyces bailii. Antibiotics. 2012
- The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma. Genes and Immunity. 2012
- Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a specific substrate of yeast metacaspase. Biochimica Et Biophysica Acta-Molecular Cell Research. 2011
- The C Allele of rs5743836 Polymorphism in the Human TLR9 Promoter Links IL-6 and TLR9 Up-Regulation and Confers Increased B-Cell Proliferation. Antibiotics. 2011
- Yeast chronological lifespan and proteotoxic stress: Is autophagy good or bad?. Biochemical SocIETy Transactions. 2011
- The bacterial exotoxin AIP56 induces fish macrophage and neutrophil apoptosis using mechanisms of the extrinsic and intrinsic pathways. Fish & Shellfish Immunology. 2011
- Accumulation of Non-Superoxide Anion Reactive Oxygen Species Mediates Nitrogen-Limited Alcoholic Fermentation by Saccharomyces cerevisiae. Applied and Environmental Microbiology. 2010
- Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence.. Aging-Us. 2010
- Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H 2 O 2 and superoxide dismutase activity. Proceedings of the National Academy of Sciences of the United States of America. 2010
- Expressing and functional analysis of mammalian apoptotic regulators in yeast. Cell Death and Differentiation. 2010
- The roles played by Aspergillus nidulans apoptosis-inducing factor (AIF)-like mitochondrial oxidoreductase (AifA) and NADH-ubiquinone oxidoreductases (NdeA-B and NdiA) in farnesol resistance. Fungal Genetics and Biology. 2010
- Cdc42p controls yeast-cell shape and virulence of Paracoccidioides brasiliensis. Fungal Genetics and Biology. 2009
- Metal stress induces programmed cell death in aquatic fungi. Aquatic Toxicology. 2009
- Yeast protein expression profile during acetic acid-induced apoptosis indicates causal involvement of the TOR pathway. Proteomics. 2009
- Drug-induced apoptosis in yeast. Biochimica Et Biophysica Acta-Molecular Cell Research. 2008
- Joined in death: Highlights of the sixth international meeting on Yeast Apoptosis in Leuven, Belgium, 30 April-4 May 2008. Yeast. 2008
- NO-mediated apoptosis in yeast. Journal of Cell Science. 2007
- Nitric Oxide Signaling Is Disrupted in the Yeast Model for Batten Disease. Endocrinology. 2007
- An atypical active cell death process underlies the fungicidal activity of ciclopirox olamine against the yeast Saccharomyces cerevisiae. FEMS Yeast Research. 2007
- Low auxotrophy-complementing amino acid concentrations reduce yeast chronological life span. Mechanisms of Ageing and Development. 2007
- Genome size and ploidy of Paracoccidioides brasiliensis reveals a haploid DNA content: Flow cytometry and GP43 sequence analysis. Fungal Genetics and Biology. 2007
- Multiplex PCR identification of eight clinically relevant Candida species. Blood. 2007
- Towards a molecular genetic system for the pathogenic fungus Paracoccidioides brasiliensis. Fungal Genetics and Biology. 2007
- A twenty-year survey of dermatophytoses in Braga, Portugal. International Journal of Dermatology. 2006
- Hyperosmotic stress induces metacaspase - and mitochondria - dependent apoptosis in Saccharomyces cerevisiae. Molecular Microbiology. 2005
- Yeast programmed cell death: An intricate puzzle. Iubmb Life. 2005
- An AIF orthologue regulates apoptosis in yeast. Journal of Cell Biology. 2004
- Energy conversion coupled to cyanide-resistant respiration in the yeasts and. FEMS Yeast Research. 2003
- Acetic acid induces a programmed cell death process in the food spoilage yeast Zygosaccharomyces bailii. FEMS Yeast Research. 2003
- The Spoilage Yeast Zygosaccharomyces bailii Forms Mitotic Spores: a Screening Method for Haploidization. Applied and Environmental Microbiology. 2003
- Cytochrome c release and mitochondria involvement in programmed cell death induced by acetic acid in Saccharomyces cerevisiae. Endocrinology. 2002
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capítulo de livro
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documento
- Exploring Connexin-43 Dynamics: Yeast as a Model System 2024
- The action of the sweeteners cyclamate and saccharin on the chronological aging of Saccharomyces cerevisiae 2023
- Analysis of autophagy in different organs of mice subjected to different diets 2023
- Analysis of Autophagy Pattern in Mice under Different Dietary Regimens 2023
- Detecção não invasiva de doença residual mínima em leucemia mielóide aguda usando um sistema de microfluídica para o isolamento e concentração de blastos leucémicos em sangue periférico ou em médula óssea 2021
- Isolation and concentration of acute myeloid leukemia blasts in measurable residual disease using a microfluidic system 2021
- Isolation of Acute Myeloid Leukemia Blasts Using a Microfluidic System for Accurate Assessment of Minimal Residual Disease 2021
- Microfluidics Platform for the Detection of Minimal Residual Disease in Acute Myeloid Leukemia 2021
- Desenvolvimento de uma Plataforma de Microfuídica para Diagnóstico e Monitorização de Doença Residual Mínima em Leucemia Mielóide Aguda 2020
- Desenvolvimento de uma plataforma de microfluídica para diagnóstico e monitorização de doença residual mínima em leucemia mielóide aguda 2020
- CLINICAL IMPLICATIONS OF THE AUTOPHAGY CORE GENE VARIATIONS IN ACUTE MYELOID LEUKEMIA 2019
- INTEGRATION OF LIPID METABOLISM WITH KREBS CYCLE IN ACUTE MYELOID LEUKEMIA§ 2019
- A microfluidics platform for the SERS-based detection of acute myeloid leukemia 2019
- Interplay between energetic metabolism and autophagic regulation in acute myeloid leukemia cells 2018
- Interplay between glutaminolysis and autophagy in acute myeloid leukemia cells 2018
- Messenger molecules modulating yeast chronological aging 2018
- Cell signaling pathways and autophagy regulation in acute myeloid leukemia 2017
- Energy metabolism in acute myeloid leukemia cells 2017
- Glutaminolysis and autophagy interplay in acute myeloid leukemia cells 2017
- Metabolic cell signalling pathways and autophagy regulation in acute myeloid leukemia cells 2017
- Metal stress induces programmed cell death in aquatic fungi 2009
- Involvement of eEF1A in acetic acid-induced apoptosis in yeast 2008
- Role of Lcb5p in oxidative stress resistance and ageing in yeast 2007
- Role of Isc1 in oxidative stress resistance and ageing in yeast 2006
- Yeast neutral sphingomyelinase Isc1p: role in cell death associated with oxidative stress and ageing 2005
- The role of the yeast neutral sphingomyelinase Isc1p in cell death associated with oxidative stress and ageing 2004