publicações selecionadas
-
artigo académico
- Reply to Dietvorst et al. Challenges in Providing an Overview of Results of Intermittent Fasting Interventions on Diabetes Parameters. Comment on “Silva et al. Effects of Intermittent Fasting on Regulation of Metabolic Homeostasis: A Systematic Review and Meta-Analysis in Health and Metabolic-Related Disorders. J. Clin. Med. 2023, 12, 3699”. International Wound Journal. 2024
- Prevascularized spongy-like hydrogels maintain their angiogenic potential after prolonged hypothermic storage. Bioactive Materials. 2024
- Inflammation and Exosomes in Fabry Disease Pathogenesis. Cells. 2024
- The Yeast Protein Kinase Sch9 Functions as a Central Nutrient-Responsive Hub That Calibrates Metabolic and Stress-Related Responses. Journal of Invasive Fungal Infections. 2023
- Effects of Intermittent Fasting on Regulation of Metabolic Homeostasis: A Systematic Review and Meta-Analysis in Health and Metabolic-Related Disorders. International Wound Journal. 2023
- Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization. International Journal of Molecular Sciences. 2023
- Current and Emerging Techniques for Diagnosis and MRD Detection in AML: A Comprehensive Narrative Review. Cancers. 2023
- Anti-Aging and Neuroprotective Properties of Grifola frondosa and Hericium erinaceus Extracts. Nutrients. 2022
- Innovative, integrative, and interactive in-class activity on metabolic regulation: Evaluating educational impacts. Biochemistry and Molecular Biology Education. 2021
- Functional Genetic Variants in ATG10 Are Associated with Acute Myeloid Leukemia. Cancers. 2021
- Polymorphisms within Autophagy-Related Genes Influence the Risk of Developing Colorectal Cancer: A Meta-Analysis of Four Large Cohorts. Cancers. 2021
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021
- Unravelling the anticancer potential of functionalized chromeno[2,3-b ] pyridines for breast cancer treatment. Bioorganic Chemistry. 2020
- Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot. Biology. 2020
- Elucidating the mechanisms of action of parecoxib in the MG-63 osteosarcoma cell line. Anti-Cancer Drugs. 2020
- The antifungal plant defensin HsAFP1 induces autophagy, vacuolar dysfunction and cell cycle impairment in yeast. Biochimica et Biophysica Acta (BBA). Biomembranes. 2020
- Targeting Metabolic Reprogramming in Acute Myeloid Leukemia. Cells. 2019
- a-Synuclein toxicity in yeast and human cells is caused by cell cycle re-entry and autophagy degradation of ribonucleotide reductase 1. Aging Cell. 2019
- Transcriptomic and chemogenomic analyses unveil the essential role of Com2-regulon in response and tolerance of Saccharomyces cerevisiae to stress induced by sulfur dioxide. Microbial Cell. 2019
- Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology. Cell Death and Differentiation. 2018
- Exploitation of New Chalcones and 4H-chromenes as Agents for Cancer Treatment. European Journal of Medicinal Chemistry. 2018
- Signalling mechanisms that regulate metabolic profile and autophagy of acute myeloid leukaemia cells. Journal of Cellular and Molecular Medicine. 2018
- From Regulated Cell Death to Adaptive Stress Strategies: Convergence and Divergence in Eukaryotic Cells. Oxidative Medicine and Cellular Longevity. 2018
- Linking cellular proteostasis to yeast longevity. FEMS Yeast Research. 2018
- pH homeostasis links the nutrient sensing PKA/TORC1/Sch9 ménage-à-trois to stress tolerance and longevity. Microbial Cell. 2018
- Caloric restriction rescues yeast cells from alpha-synuclein toxicity through autophagic control of proteostasis. Aging-Us. 2018
- Guidelines and recommendations on yeast cell death nomenclature. Microbial Cell. 2018
- New perspectives from South-Y-East, not all about death A report of the 12th lnternational Meeting on Yeast Apoptosis in Bari, Italy, May 14th-18th, 2017. Microbial Cell. 2018
- The sensitivity of the yeast, Saccharomyces cerevisiae, to acetic acid is influenced by DOM34 and RPL36A. African Journal of Biotechnology. 2017
- Cell sheet engineering using the stromal vascular fraction of adipose tissue as a vascularization strategy. Acta Biomaterialia. 2017
- Lipocalin-2 regulates adult neurogenesis and contextual discriminative behaviours. Elife. 2017
- Caloric restriction alleviates alpha-synuclein toxicity in aged yeast cells by controlling the opposite roles of Tor1 and Sir2 on autophagy. Mechanisms of Ageing and Development. 2017
- Chronic stress triggers tau pathology through autophagy inhibition and induction of stress granules. Journal of Neurochemistry. 2017
- Increasing the Fungicidal Action of Amphotericin B by Inhibiting the Nitric Oxide-Dependent Tolerance Pathway. Oxidative Medicine and Cellular Longevity. 2017
- The Role of Nitric Oxide Signalling in Yeast Stress Response and Cell Death. Handbook of Microbial Metabolism of Amino Acids. 2017
- Yeast on the corner of life and death decisions. Mechanisms of Ageing and Development. 2017
- Mitochondrial proteomics of the acetic acid - induced programmed cell death response in a highly tolerant Zygosaccharomyces bailii - derived hybrid strain. Microbial Cell. 2016
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016
- The "stressed" autophagy: chronic stress exacerbates Tau pathology by blocking autophagy clearance system. Brain Structure and Function. 2016
- IL-17A Promotes Intracellular Growth of Mycobacterium by Inhibiting Apoptosis of Infected Macrophages. Frontiers in Immunology. 2015
- Sirtuins and Proteolytic Systems: Implications for Pathogenesis of Synucleinopathies. Biomolecules. 2015
- Bioresorbable ureteral stents from natural origin polymers. Journal of Biomedical Materials Research: Part B. 2015
- The Role of Autophagy on the Differentiation Potential of Adipose Stromal Cell Sheets under Normoxia vs Hypoxia 2015
- Proteolytic systems and AMP-activated protein kinase are critical targets of acute myeloid leukemia therapeutic approaches. Oncotarget. 2014
- Proteomic Analysis of the Action of the Mycobacterium ulcerans Toxin Mycolactone: Targeting Host Cells Cytoskeleton and Collagen. PLoS Neglected Tropical Diseases. 2014
- Longevity pathways and maintenance of the proteome: the role of autophagy and mitophagy during yeast ageing. Microbial Cell. 2014
- Reactive oxygen species, ageing and the hormesis police. FEMS Yeast Research. 2013
- Involvement of Yeast HSP90 Isoforms in Response to Stress and Cell Death Induced by Acetic Acid 2013
- DNA replication stress-induced loss of reproductive capacity inS. cerevisiaeand its inhibition by caloric restriction. Cell Cycle. 2013
- P. brasiliensis Virulence Is Affected by SconC, the Negative Regulator of Inorganic Sulfur Assimilation 2013
- Yeast Stress, Aging, and Death. Oxidative Medicine and Cellular Longevity. 2013
- SNCA (a-synuclein)-induced toxicity in yeast cells is dependent on Sir2-mediated mitophagy. Autophagy. 2012
- Functionality of the Paracoccidioides Mating a-Pheromone-Receptor System 2012
- Morphological heterogeneity of Paracoccidioides brasiliensis: Relevance of the Rho-like GTPase PbCDC42. Blood. 2012
- An alternative respiratory pathway on Candida krusei: implications on susceptibility profile and oxidative stress. FEMS Yeast Research. 2012
- Cellular Models of Aging. Oxidative Medicine and Cellular Longevity. 2012
- The Fate of Acetic Acid during Glucose Co-Metabolism by the Spoilage Yeast Zygosaccharomyces bailii 2012
- The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma. Genes and Immunity. 2012
- Yeast as a platform to uncover ceramide-induced ancient cell death routines. Cell Cycle. 2012
- Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a specific substrate of yeast metacaspase. Biochimica Et Biophysica Acta-Molecular Cell Research. 2011
- The C Allele of rs5743836 Polymorphism in the Human TLR9 Promoter Links IL-6 and TLR9 Up-Regulation and Confers Increased B-Cell Proliferation 2011
- The bacterial exotoxin AIP56 induces fish macrophage and neutrophil apoptosis using mechanisms of the extrinsic and intrinsic pathways. Fish & Shellfish Immunology. 2011
- Yeast chronological lifespan and proteotoxic stress: Is autophagy good or bad?. Biochemical SocIETy Transactions. 2011
- Accumulation of Non-Superoxide Anion Reactive Oxygen Species Mediates Nitrogen-Limited Alcoholic Fermentation by Saccharomyces cerevisiae. Applied and Environmental Microbiology. 2010
- Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence.. Aging-Us. 2010
- Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H 2 O 2 and superoxide dismutase activity. Proceedings of the National Academy of Sciences of the United States of America. 2010
- Overeating yeast display fatty acid-induced necrotic cell death. Cell Cycle. 2010
- Expressing and functional analysis of mammalian apoptotic regulators in yeast. Cell Death and Differentiation. 2010
- The roles played by Aspergillus nidulans apoptosis-inducing factor (AIF)-like mitochondrial oxidoreductase (AifA) and NADH-ubiquinone oxidoreductases (NdeA-B and NdiA) in farnesol resistance. Fungal Genetics and Biology. 2010
- Cdc42p controls yeast-cell shape and virulence of Paracoccidioides brasiliensis. Fungal Genetics and Biology. 2009
- Metal stress induces programmed cell death in aquatic fungi. Aquatic Toxicology. 2009
- Mismatches between the conceptual level of tests and faculty beliefs. Faseb Journal. 2009
- Neurodevelopmental delay in the Cln3(Delta ex7/8) mouse model for Batten disease. Genes, Brain and Behavior. 2009
- Yeast protein expression profile during acetic acid-induced apoptosis indicates causal involvement of the TOR pathway. Proteomics. 2009
- Drug-induced apoptosis in yeast. Biochimica Et Biophysica Acta-Molecular Cell Research. 2008
- Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and apoptosis. Molecular Biology of the Cell. 2008
- Joined in death: Highlights of the sixth international meeting on Yeast Apoptosis in Leuven, Belgium, 30 April-4 May 2008. Yeast. 2008
- Singular yeast cell morphology of Paracoccidioides brasiliensis is associated to virulence: down-regulation of the CDC42 homolog. The FEBS Journal. 2008
- Studying the role of nitric oxide in the pathological mechanism of Batten disease. The FEBS Journal. 2008
- NO-mediated apoptosis in yeast. Journal of Cell Science. 2007
- Nitric Oxide Signaling Is Disrupted in the Yeast Model for Batten Disease. Molecular Biology of the Cell. 2007
- An atypical active cell death process underlies the fungicidal activity of ciclopirox olamine against the yeast Saccharomyces cerevisiae. FEMS Yeast Research. 2007
- Genome size and ploidy of Paracoccidioides brasiliensis reveals a haploid DNA content: Flow cytometry and GP43 sequence analysis. Fungal Genetics and Biology. 2007
- Low auxotrophy-complementing amino acid concentrations reduce yeast chronological life span. Mechanisms of Ageing and Development. 2007
- Multiplex PCR identification of eight clinically relevant Candida species. Blood. 2007
- Towards a molecular genetic system for the pathogenic fungus Paracoccidioides brasiliensis. Fungal Genetics and Biology. 2007
- A twenty-year survey of dermatophytoses in Braga, Portugal. International Journal of Dermatology. 2006
- Role of Isc1p in oxidative stress resistance and ageing in yeast. Chemistry and Physics of Lipids. 2006
- Hyperosmotic stress induces metacaspase - and mitochondria - dependent apoptosis in Saccharomyces cerevisiae. Molecular Microbiology. 2005
- Yeast programmed cell death: An intricate puzzle. Iubmb Life. 2005
- An AIF orthologue regulates apoptosis in yeast. Journal of Cell Biology. 2004
- Saccharomyces cerevisiae commits to programmed cell death in response to hyperosmotic stress caused by glucose. Cytometry Part A. 2004
- Energy conversion coupled to cyanide-resistant respiration in the yeasts and. FEMS Yeast Research. 2003
- Acetic acid induces a programmed cell death process in the food spoilage yeast. FEMS Yeast Research. 2003
- Acetic acid induces a programmed cell death process in the food spoilage yeast Zygosaccharomyces badii (vol 2, pg 91, 2003). FEMS Yeast Research. 2003
- Acetic acid induces a programmed cell death process in the food spoilage yeast Zygosaccharomyces bailii. FEMS Yeast Research. 2003
- Sphingolipid signalling in stress resistance and chronological life-span in Saccharomyces cerevisiae: the role of Isc1p. Yeast. 2003
- The Spoilage Yeast Zygosaccharomyces bailii Forms Mitotic Spores: a Screening Method for Haploidization. Applied and Environmental Microbiology. 2003
- Cytochrome c release and mitochondria involvement in programmed cell death induced by acetic acid in Saccharomyces cerevisiae. Molecular Biology of the Cell. 2002
- Assessment of mitochondrial membrane potential in yeast cell populations by flow cytometry. Microbiology. 2001
- Programmed cell death in Saccharomyces cerevisiae induced by acetic acid.. Yeast. 2001
- Saccharomyces cerevisiae commits to a programmed cell death process in response to acetic acid. Microbiology. 2001
-
artigo de conferência
- The role of autophagy on the differentiation potential of adipose stromal cell sheets under normoxia vs hypoxia 2015
- Evaluation of the protective effect of Hypericum perforatum phenolics compounds, in the toxicity induced by heterologous expression of a-synuclein 2011
- Hypericum perforatum phenolics compounds: protective role in the toxicity induced by heterologous expression of a-synuclein 2011
-
capítulo de livro
-
documento
- Non-invasive profiling of Fabry disease: molecular fingerprints from plasma and extracellular vesicles 2026
- Differential miRNA Expression in Plasma Vesicles Across Fabry Disease Phenotypes 2025
- Extracellular Vesicle miRNA Signatures in Fabry Disease 2025
- Autophagy characterization in Acomys cahirinus across Great Rift Valley bioclimates 2024
- Exosomes as Inflammatory Mediators in Fabry Disease 2024
- Influence of sweeteners on cell signaling during yeast growth and aging 2024
- Insights into ATG16L1 Influence on Exosome Production and Cardiac Homeostasis: A Proteomic Study 2024
- Yeast as a model for investigating Connexin-43: Insights into Cellular Communication and Proteostasis 2024
- Effects of non-caloric sweeteners on the lifespan of Saccharomyces cerevisiae 2024
- Dietary and Habitat-driven regulation of autophagy in mouse organ systems 2024
- Exploiting the Relevance of WNT6 in Extracellular Vesicles of Glioblastoma: Clinical and Molecular Insights 2024
- The action of the sweeteners cyclamate and saccharin on the chronological aging of Saccharomyces cerevisiae 2023
- Analysis of autophagy in different organs of mice subjected to different diets 2023
- Analysis of Autophagy Pattern in Mice under Different Dietary Regimens 2023
- Detecção não invasiva de doença residual mínima em leucemia mielóide aguda usando um sistema de microfluídica para o isolamento e concentração de blastos leucémicos em sangue periférico ou em médula óssea 2021
- Isolation and concentration of acute myeloid leukemia blasts in measurable residual disease using a microfluidic system 2021
- Isolation of Acute Myeloid Leukemia Blasts Using a Microfluidic System for Accurate Assessment of Minimal Residual Disease 2021
- Microfluidics Platform for the Detection of Minimal Residual Disease in Acute Myeloid Leukemia 2021
- Desenvolvimento de uma Plataforma de Microfuídica para Diagnóstico e Monitorização de Doença Residual Mínima em Leucemia Mielóide Aguda 2020
- Desenvolvimento de uma plataforma de microfluídica para diagnóstico e monitorização de doença residual mínima em leucemia mielóide aguda 2020
- CLINICAL IMPLICATIONS OF THE AUTOPHAGY CORE GENE VARIATIONS IN ACUTE MYELOID LEUKEMIA 2019
- INTEGRATION OF LIPID METABOLISM WITH KREBS CYCLE IN ACUTE MYELOID LEUKEMIA§ 2019
- A microfluidics platform for the SERS-based detection of acute myeloid leukemia 2019
- Interplay between energetic metabolism and autophagic regulation in acute myeloid leukemia cells 2018
- Interplay between glutaminolysis and autophagy in acute myeloid leukemia cells 2018
- Messenger molecules modulating yeast chronological aging 2018
- Cell signaling pathways and autophagy regulation in acute myeloid leukemia 2017
- Energy metabolism in acute myeloid leukemia cells 2017
- Glutaminolysis and autophagy interplay in acute myeloid leukemia cells 2017
- Metabolic cell signalling pathways and autophagy regulation in acute myeloid leukemia cells 2017
- Involvement of eEF1A in acetic acid-induced apoptosis in yeast 2008
- Role of Lcb5p in oxidative stress resistance and ageing in yeast 2007
- Role of Isc1 in oxidative stress resistance and ageing in yeast 2006
- Yeast neutral sphingomyelinase Isc1p: role in cell death associated with oxidative stress and ageing 2005
- The role of the yeast neutral sphingomyelinase Isc1p in cell death associated with oxidative stress and ageing 2004