publicações selecionadas
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artigo académico
- Cisplatin-Resistant Urothelial Bladder Cancer Cells Undergo Metabolic Reprogramming beyond the Warburg Effect. Cancers. 2024
- Glucose Metabolism as a Potential Therapeutic Target in Cytarabine-Resistant Acute Myeloid Leukemia. Pharmaceutics. 2024
- Effects of Lactate Transport Inhibition by AZD3965 in Muscle-Invasive Urothelial Bladder Cancer. Pharmaceutics. 2023
- Sustainable fluorescent dye-faujasite zeolite systems as tools for cancer bioimaging 2023
- Extracellular Matrix Collagen I Differentially Regulates the Metabolic Plasticity of Pancreatic Ductal Adenocarcinoma Parenchymal Cell and Cancer Stem Cell. Cancers. 2023
- Immunoexpression profile of hypoxia-inducible factor (HIF) targets in potentially malignant and malignant oral lesions: a pilot study. Journal of Applied Oral Science. 2023
- Prognostic Value of Monocarboxylate Transporter 1 Overexpression in Cancer: A Systematic Review. International Journal of Molecular Sciences. 2023
- Modulating chitosan-PLGA nanoparticle properties to design a co-delivery platform for glioblastoma therapy intended for nose-to-brain route. Drug Delivery and Translational Research. 2020
- IL-17A and IL-17F orchestrate macrophages to promote lung cancer. Cellular Oncology. 2020
- Lactate Beyond a Waste Metabolite: Metabolic Affairs and Signaling in Malignancy. Frontiers in Oncology. 2020
- Competitive glucose metabolism as a target to boost bladder cancer immunotherapy. Nature Reviews Urology. 2020
- A novel strategy for glioblastoma treatment combining alpha-cyano-4-hydroxycinnamic acid with cetuximab using nanotechnology-based delivery systems. Drug Delivery and Translational Research. 2020
- The metabolic landscape of urological cancers: New therapeutic perspectives. Cancer Letters. 2020
- Targeting lactate transport suppresses in vivo breast tumour growth.. Oncotarget. 2015
- Disruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 status. Oncotarget. 2015
- Urothelial bladder cancer progression: lessons learned from the bench. Journal of Cancer Metastasis and Treatment. 2015
- Gene Disruption Using Zinc Finger Nuclease Technology. Methods in Molecular Biology. 2014
- How to decipher a microbial puzzle on microbial control : hands on. Online International Interdisciplinary Research Journal. 2014
- Monocarboxylate Transporters as Targets and Mediators in Cancer Therapy Response. Histology and Histopathology. 2014
- A Hospital Based Cohort Study of Colorectal Cancer Cases Treated at Braga Hospital, Northern Portugal. Journal of Gastrointestinal & Digestive System. 2013
- Contribution of Monocarboxylate Transporters to the Aggressive Phenotype of Breast Cancer. Annals of Oncology. 2013
- Lactate-Induced IL-8 Pathway in Endothelial Cells--Letter. Cancer Research. 2012
- GLUT1 and CAIX expression profiles in breast cancer correlate with adverse prognostic factors and MCT1 overexpression.. Histology and Histopathology. 2011
- Lymphatic Vessel Density in the Normal-Looking Columnar Epithelium Adjacent to and Distant from Prostatic Intraepithelial Neoplasia and Prostate Cancer Assessed in Whole-Mount Sections. Analytical and Quantitative Cytology and Histology. 2009
- Monocarboxylate transporters 2 and 4 are upregulated in prostate carcinoma. Virchows Archiv. 2009
- Specificity of the anti-glycolytic activity of 3-bromopyruvate confirmed by FDG uptake in a rat model of breast cancer. Investigational New Drugs. 2008
- Apoptosis detected by cleaved cytokeratin 18 (M30) immunohistochemistry in colorectal cancer is related to acidic tumoral microenviroment. Histopathology. 2008
- CD147 expression correlates with monocarboxylate transporters 1 and 4 in cervical carcinoma. Ejc Supplements. 2008
- Increased apoptosis in gastric carcinogenesis progression can be influenced by mechanisms involved in tumoral microenviroment pH control. Histopathology. 2008
- Monocarboxylate transporter expression correlates with CD147 and HIF-1 alpha in gastric cancermonocarboxylate transporter expression correlates with CD147 and HIF-1 alpha in gastric cancer. Virchows Archiv. 2008
- Immunohistochemical expression of VEGF-A and its ligands in non-neoplastic lesions of the breast sampling-assisted by dynamic angiothermography.. Oncology Reports. 2007
- Altered expression of monocarboxylate transporters 1, 2 and 4 in colorectal carcinomas. Virchows Archiv. 2007
- Recurrent EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. Modern Pathology. 2006
- L-[U-14C] lactate binding to a 43 kDa protein in plasma membranes of Candida utilis.. Microbiology. 2000
- Oxidation of medium-chain acyl-CoA esters by extracts of Aspergillus niger: enzymology and characterization of intermediates by HPLC.. Microbiology-Uk. 1999
- Clinical impact of the metabolic phenotype of prostate cancer: role of monocarboxylate transporters (MCTs).
- Exploiting monocarboxylate transporters as new molecular targets for colorectal carcinoma therapy.
- Modulation of DNA damage prevention and signaling pathways in diet induced colon cancer prevention.
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artigo de conferência
- Dual nanomaterial systems aiming antimicrobial activity and cancer treatment 2018
- Enhancing 5-FU activity in colorectal carcinoma-derived cell lines: combination with monocarboxylate transporter inhibitors and encapsulation into zeolites 2012
- Zeolites: promising candidates for drug delivery systems (DDSs) 2012
- DNA damage prevention and signaling pathway regulation by sage in a colon cancer model 2011
- Diet and colon cancer - modulation of signaling pathways and DNA damage prevention 2011
- Monocarboxylate transporters - new molecular targets for colorectal carcinoma? 2011
- Monocarboxylate transporters as new attractive targets for colorectal carcinoma therapy 2011
- Search for portuguese propolis antimicrobial activity in a wide range of microorganisms 2011
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artigo de revista
- Optimization of iron-ZIF-8 catalysts for degradation of tartrazine in water by Fenton-like reaction. Chemosphere. 2023
- Phenolic Compounds Contribution to Portuguese Propolis Anti-Melanoma Activity. Biomolecules. 2023
- Glucose Metabolism Reprogramming in Bladder Cancer: Hexokinase 2 (HK2) as Prognostic Biomarker and Target for Bladder Cancer Therapy. Cancers. 2023
- Targeting Lysosomes in Colorectal Cancer: Exploring the Anticancer Activity of a New Benzo[a]phenoxazine Derivative. International Journal of Molecular Sciences. 2022
- 3-Bromopyruvate Suppresses the Malignant Phenotype of Vemurafenib-Resistant Melanoma Cells. International Journal of Molecular Sciences. 2022
- Microbiota-Derived Short-Chain Fatty Acids: New Road in Colorectal Cancer Therapy. Pharmaceutics. 2022
- Selective Cytotoxicity of Portuguese Propolis Ethyl Acetate Fraction towards Renal Cancer Cells. Biomolecules. 2022
- Portuguese Propolis Antitumoral Activity in Melanoma Involves ROS Production and Induction of Apoptosis. Biomolecules. 2022
- In Vitro CRISPR/Cas9 Transfection and Gene-Editing Mediated by Multivalent Cationic Liposome-DNA Complexes. Pharmaceutics. 2022
- Magnetic Solid Nanoparticles and Their Counterparts: Recent Advances towards Cancer Theranostics. Pharmaceutics. 2022
- Colon microbiota modulation by dairy-derived diet: new strategy for prevention and treatment of colorectal cancer. Food Bioscience. 2022
- In Vivo Anticancer Activity of AZD3965: A Systematic Review. Biomolecules. 2021
- MCT1 Is a New Prognostic Biomarker and Its Therapeutic Inhibition Boosts Response to Temozolomide in Human Glioblastoma. Cancers. 2021
- Cancer Cells’ Metabolism Dynamics in Renal Cell Carcinoma Patients’ Outcome: Influence of GLUT-1-Related hsa-miR-144 and hsa-miR-186. Cancers. 2021
- Nestin Expression Is Associated with Relapses in Head and Neck Lesions. Diagnostics. 2021
- Disruption of pH Dynamics Suppresses Proliferation and Potentiates Doxorubicin Cytotoxicity in Breast Cancer Cells. Pharmaceutics. 2021
- The Role of Diet Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications. Current Medicinal Chemistry. 2020
- Microbes and Cancer: Friends or Faux?. International Journal of Molecular Sciences. 2020
- Immunity, hypoxia, and metabolism–the ménage à trois of cancer: Implications for immunotherapy. Physiological Reviews. 2020
- Fucoidan from Fucus vesiculosus inhibits new blood vessel formation and breast tumor growth in vivo. Carbohydrate Polymers. 2019
- Magnetoliposomes Containing Calcium Ferrite Nanoparticles for Applications in Breast Cancer Therapy. Pharmaceutics. 2019
- Direct actions of adiponectin on changes in reproductive, metabolic, and anti-oxidative enzymes status in the testis of adult mice. General and Comparative Endocrinology. 2019
- Clinical significance of metabolism-related biomarkers in non-Hodgkin lymphoma - MCT1 as potential target in diffuse large B cell lymphoma. Cellular Oncology. 2019
- Rational Identification of a Colorectal Cancer Targeting Peptide through Phage Display. Acta Cytologica. 2019
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Photodynamic Therapy at Low-Light Fluence Rate:
in vitro Assays on Colon Cancer Cells. IEEE Journal of Selected Topics in Quantum Electronics. 2019 - Role of adiponectin as a modulator of testicular function during aging in mice. Biochimica et Biophysica Acta (BBA). Molecular Basis of Disease. 2019
- Synthesis, characterization and in vitro validation of a magnetic zeolite nanocomposite with T2-MRI properties towards theranostic applications. Journal of Materials Chemistry B. 2019
- Exploitation of New Chalcones and 4H-chromenes as Agents for Cancer Treatment. European Journal of Medicinal Chemistry. 2018
- Adenine Derivatives: Promising Candidates for Breast Cancer Treatment. European Journal of Organic Chemistry. 2018
- Bioenergetic modulators hamper cancer cell viability and enhance response to chemotherapy. Journal of Cellular and Molecular Medicine. 2018
- The clinicopathological significance of monocarboxylate transporters in testicular germ cell tumors. Oncotarget. 2018
- Internalization studies on zeolite nanoparticles using human cells. Journal of Materials Chemistry B. 2018
- Monocarboxylate transporter 1 is a key player in glioma-endothelial cell crosstalk. Molecular Carcinogenesis. 2017
- Metabolic alterations underlying Bevacizumab therapy in glioblastoma cells. Oncotarget. 2017
- Impact of mesenchymal stem cells' secretome on glioblastoma pathophysiology. Journal of Translational Medicine. 2017
- Alginate hydrogel improves anti-angiogenic bevacizumab activity in cancer therapy. European Journal of Pharmaceutics and Biopharmaceutics. 2017
- Value of pH regulators in the diagnosis, prognosis and treatment of cancer. Seminars in Cancer Biology. 2017
- Comparison of different silica microporous structures as drug delivery systems for in vitro models of solid tumors. Nanoscale. 2017
- GLUT1 expression in pediatric adrenocortical tumors: A promising candidate to predict clinical behavior. Oncotarget. 2017
- HER Family Receptors are Important Theranostic Biomarkers for Cervical Cancer: Blocking Glucose Metabolism Enhances the Therapeutic Effect of HER Inhibitors. Theranostics. 2017
- The expression of monocarboxylate transporters in thyroid carcinoma can be associated with the morphological features of BRAF V600E mutation. Endocrine. 2016
- Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas. Oncotarget. 2016
- Absence of microsatellite instability and BRAF (V600E) mutation in testicular germ cell tumors.. Andrology. 2016
- Metabolic coupling in urothelial bladder cancer compartments and its correlation to tumor aggressiveness. Cell Cycle. 2016
- Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications. Oncotarget. 2016
- Prognostic significance of monocarboxylate transporter expression in oral cavity tumors. Cell Cycle. 2016
- Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis. BMC Cancer. 2016
- The anticancer agent 3-bromopyruvate: a simple but powerful molecule taken from the lab to the bedside. Journal of Bioenergetics and Biomembranes. 2016
- The metabolic microenvironment of melanomas: Prognostic value of MCT1 and MCT4. Cell Cycle. 2016
- Colon Cancer Chemoprevention by Sage Tea Drinking: Decreased DNA Damage and Cell Proliferation. Phytotherapy Research. 2015
- Lactate transporters and pH regulation: potential therapeutic targets in glioblastomas.. Current Cancer Drug Targets. 2015
- Hotspot TERT promoter mutations are rare events in testicular germ cell tumors.. Tumor Biology. 2015
- Glucose Addiction in Cancer Therapy: Advances and Drawbacks.. Current Drug Metabolism. 2015
- A glycolytic phenotype is associated with prostate cancer progression and aggressiveness: a role for monocarboxylate transporters as metabolic targets for therapy.. Journal of Pathology. 2015
- Monocarboxylate transport inhibition potentiates the cytotoxic effect of 5-fluorouracil in colorectal cancer cells. Cancer Letters. 2015
- Cathepsin D protects colorectal cancer cells from acetate-induced apoptosis through autophagy-independent degradation of damaged mitochondria. Cell Death and Differentiation. 2015
- Micro- and Mesoporous Structures as Drug Delivery Carriers for Salicylic Acid. Journal of Physical Chemistry C. 2015
- Localization of MCT2 at peroxisomes is associated with malignant transformation in prostate cancer. Journal of Cellular and Molecular Medicine. 2015
- CD147 and MCT1 - potential partners in bladder cancer aggressiveness and cisplatin resistance. Molecular Carcinogenesis. 2015
- Evolving hallmarks in urothelial bladder cancer: unveiling potential biomarkers. Acta Urológica Portuguesa. 2015
- Impact of an educational hands-on project on the antimicrobial, antitumor and anti-inflammatory properties of plants on Portuguese students' awareness, knowledge, and competences. Healthcare. 2015
- In vitro and in vivo studies of temozolomide loading in zeolite structures as drug delivery systems for glioblastoma. Nanoscale. 2015
- Metabolic reprogramming: A new relevant pathway in adult adrenocortical tumors. Oncotarget. 2015
- Propolis: A Complex Natural Product with a Plethora of Biological Activities That Can Be Explored for Drug Development. Evidence-based Complementary and Alternative Medicine. 2015
- Reprogramming energy metabolism and inducing angiogenesis: Co-expression of monocarboxylate transporters with VEGF family members in cervical adenocarcinomas. BMC Cancer. 2015
- SMYD3 contributes to a more aggressive phenotype of prostate cancer and targets Cyclin D2 through H4K20me3. Oncotarget. 2015
- The cytotoxicity of 3-bromopyruvate in breast cancer cells depends on extracellular pH. Biochemical Journal. 2015
- Antitumoural and antiangiogenic activity of Portuguese propolis in in vitro and in vivo models. Journal of Functional Foods. 2014
- Lactate Transporters in the Context of Prostate Cancer Metabolism: What Do We Know?. International Journal of Molecular Sciences. 2014
- T-box Transcription Factor Brachyury Is Associated with Prostate Cancer Progression and Aggressiveness. Clinical Cancer Research. 2014
- A lactate shuttle system between tumour and stromal cells is associated with poor prognosis in prostate cancer. BMC Cancer. 2014
- Characterization of monocarboxylate transporter activity in hepatocellular carcinoma. World Journal of Gastroenterology. 2014
- Characterization of monocarboxylate transporters (MCTs) expression in soft tissue sarcomas: distinct prognostic impact of MCT1 sub-cellular localization. Journal of Translational Medicine. 2014
- Lactate transporters and vascular factors in HPV-induced squamous cell carcinoma of the uterine cervix. BMC Cancer. 2014
- The basal epithelial marker P-cadherin associates with breast cancer cell populations harboring a glycolytic and acid-resistant phenotype. BMC Cancer. 2014
- Potentiation of 5-fluorouracil encapsulated in zeolites as drug delivery systems for in vitro models of colorectal carcinoma. Colloids and Surfaces B: Biointerfaces. 2013
- Differential sensitivities to lactate transport inhibitors of breast cancer cell lines. Endocrine-Related Cancer. 2013
- Portuguese propolis disturbs glycolytic metabolism of human colorectal cancer in vitro. BMC Complementary and Alternative Medicine. 2013
- Assessing the Impact of a School Intervention to Promote Students’ Knowledge and Practices on Correct Antibiotic Use. Healthcare. 2013
- Cancer cell bioenergetics and pH regulation influence breast cancer cell resistance to paclitaxel and doxorubicin. Journal of Bioenergetics and Biomembranes. 2013
- Loss of caveolin-1 and gain of MCT4 expression in the tumor stroma Key events in the progression from an in situ to an invasive breast carcinoma. Cell Cycle. 2013
- Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets. Neuro-Oncology. 2013
- The Monocarboxylate Transporter Inhibitor a-Cyano-4-Hydroxycinnamic Acid Disrupts Rat Lung Branching. Cellular Physiology and Biochemistry. 2013
- Zeolite Structures Loading with an Anticancer Compound As Drug Delivery Systems. Journal of Physical Chemistry C. 2012
- Monocarboxylate transporter 2 (MCT2) as putative biomarker in prostate cancer. Prostate. 2012
- CD147 immunohistochemistry discriminates between reactive mesothelial cells and malignant mesothelioma. Diagnostic Cytopathology. 2012
- 3-bromopyruvate, butyrate, monocarboxylate transporters, warburg effect. Journal of Bioenergetics and Biomembranes. 2012
- Role of monocarboxylate transporters in human cancers : state of the art. Journal of Bioenergetics and Biomembranes. 2012
- Co-expression of monocarboxylate transporter 1 (MCT1) and its chaperone (CD147) is associated with low survival in patients with gastrointestinal stromal tumors (GISTs). Journal of Bioenergetics and Biomembranes. 2012
- Encapsulation of a-cyano-4-hydroxycinnamic acid into a NaY zeolite. Journal of Materials Science. 2011
- CD147 overexpression allows an accurate discrimination of bladder cancer patients' prognosis. Ejso. 2011
- Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer.. BMC Cancer. 2011
- Role of endoglin and VEGF family expression in colorectal cancer prognosis and anti-angiogenic therapies. World Journal of Clinical Oncology. 2011
- The selective COX-2 inhibitor Etoricoxib reduces acute inflammatory markers in a model of neurogenic laryngitis but loses its efficacy with prolonged treatment. Inflammation Research. 2010
- Monocarboxylate transporter 1 is up-regulated in basal-like breast carcinoma.. Histopathology. 2010
- Expression of Monocarboxylate Transporters 1, 2, and 4 in Human Tumours and Their Association with CD147 and CD44. Biomed Research International. 2010
- Portuguese students' knowledge of antibiotics: a cross-sectional study of secondary school and university students in Braga. BMC Public Health. 2009
- Molecular characterization of EGFR, PDGFRA and VEGFR2 in cervical adenosquamous carcinoma. BMC Cancer. 2009
- Monocarboxylate transporters 1 and 4 are associated with CD147 in cervical carcinoma. Disease Markers. 2009
- The prognostic value of CD147/EMMPRIN is associated with monocarboxylate transporter 1 co-expression in gastric cancer. European Journal of Cancer. 2009
- Induction of COX-2 expression by acrolein in the rat model of hemorrhagic cystitis.. Experimental and Toxicologic Pathology. 2008
- Increased expression of monocarboxylate transporters 1, 2, and 4 in colorectal carcinomas. International Journal of Gynecological Pathology. 2008
- A New Model of Laryngitis: Neuropeptide, Cyclooxygenase, and Cytokine Profile. Laryngoscope. 2008
- Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats. Journal of Cancer Research and Clinical Oncology. 2008
- Peritumoural, but not intratumoural, lymphatic vessel density and invasion correlate with colorectal carcinoma poor-outcome markers. Virchows Archiv. 2008
- Immunohistochemical expression and distribution of VEGFR-3 in malignant mesothelioma. Diagnostic Cytopathology. 2007
- Lymphatic vessel density and epithelial D2-40 immunoreactivity in pre-invasive and invasive lesions of the uterine cervix. Gynecologic Oncology. 2007
- Cyclooxygenase-2 and epidermal growth factor receptor expressions in different histological subtypes of cervical carcinomas. International Journal of Gynecological Pathology. 2007
- Functional Purification of the Monocarboxylate Transporter of the Yeast Candida utilis. Biotechnology Letters. 2006
- EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. Journal of Pathology. 2006
- Functional expression of the lactate permease Jen1p of Saccharomyces cerevisiae in Pichia pastoris. Biochemical Journal. 2003
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capítulo de livro
- 3D culture systems as models for solid tumors and cancer metabolism 2020
- Angiogenesis and Chromene-based Antiangiogenic Therapeutic Agents 2020
- Lactate and Lactate Transporters as Key Players in the Maintenance of the Warburg Effect 2020
- New horizons on pH regulators as cancer biomarkers and targets for pharmacological intervention 2020
- Brain Tumor Metabolism — Unraveling Its Role in Finding New Therapeutic Targets 2015
- Targeting Metabolic Reprogramming as an Anti- Cancer Strategy: Aiming at Monocarboxylate Transporters 2015
-
documento
- Characterization of glycolytic metabolism of esophageal carcinomas and evaluation of its potential as therapeutic target. 2019
- Chromene derivatives: a new strategy to overcome renal cancer resistance. 2019
- Cisplatin-resistant urothelial bladder cancer cells undergo metabolic reprogramming. 2019
- Commensal gut bacteria modulate immune surveillance and promote extra-intestinal tumor overgrowth. 2019
- Disruption of cancer cell metabolism using targeted drug delivery systems. 2019
- Evaluation of antitumor activity of AZD3965 using in vivo. 2019
- Prognostic value of Monocarboxylate transporter 1 overexpression in different cancer types: a systematic review. 2019
- Unveiling the role of diet microbiome-derived short chain fatty acids in colorectal cancer metabolism. 2019
- Exploitation of novel chromene derivatives for breast cancer treatment. 2019
- Novas moléculas baseadas na unidade de cromeno como candidatas à terapia do carcinoma das células renais (CCR). 2019
- Síntese e atividade biológica de novos agentes anticancerígenos para o tratamento do cancro da mama. 2019
- Chromene-based compounds as candidates for renal cell cancer treatment. 2019
- New chromene derivatives: Unraveling the molecular mechanisms for breast cancer therapy. 2019
- In vitro and in vivo efficacy evaluation of drug delivery systems based on zeolites. 2019
- 3-Bromopyruvate pre-treatment sensitizes MOLM13 and KG-1 cell lines to chemotherapy. 2019
- Biological activity of novel targeted inhibitors for renal cell cancer therapy. 2019
- In vitro and in vivo evaluation of new chromene derivatives as potent anticancer agents. 2019
- Synthesis of functionalized chromeno[2,3-b]pyridines: promising agents for breast cancer treatment. 2019
- Uncovering the role of acetate in the prevention of colorectal cancer induced by food contaminants. 2019
- Chromene-based molecules as targeted inhibitors for renal cell cancer therapy. 2019
- New chromene-based molecules as microtubule destabilizers and pro-apoptotic agents in cancer 2018
- Dual Nanomaterial Systems Aiming Antimicrobial Activity and Cancer Treatment 2018
- Targeting oncogenic microRNAs in Triple Negative Breast Cancer using CRISPR/cas9 approach. 2018
- The role of acetate in oncogene signalling activation and metabolism in colorectal cancer. 2018
- Chemical and biological characterization of chalcones and 4H-chromenes: exploitation as anticancer agents. 2018
- Metabolic characterization and 3-bromopyruvate sensitivity screening in 12 melanoma cell lines. 2018
- Uncovering the role of acetate in the crosstalk between monocarboxylate transporters and oncogene signaling pathways in colorectal cancer 2018
- Discovery of chromene-based molecules as apoptosis-inducers by G2/M cell-arrest. 2018
- Elucidating the impact of IL-17A/F in lung cancer 2018
- Unraveling the anticancer molecular mechanisms of new chromene-based drugs. 2018
- Factorial design to optimize PLGA-chitosan polymeric nanoparticles development for Alpha-cyano-4-hydroxycinnamate (CHC) release through the nasal route. 2018
- Chromene-based drug candidates for cancer treatment. 2018
- Targeting Cancer Cell Metabolism Using Targeted Drug Delivery Systems 2018
- Hepatocellular carcinoma in non-alcoholic steatohepatitis (NASH): Clinical, histopathological aspects and immunohistochemical of metabolic and proliferative related-markers. 2017
- Encapsulation of 5-Fuoruracil into porous nanostructures for in vitro models of solid tumors 2017
- Hepatocellular carcinoma in non-alcoholic steatohepatitis (NASH) – Clinical, histopathological aspects and immunohistochemical aspects 2017
- Dietary zinc supplementation promotes tumor overgrowth through a microbiota-tumor axis 2017
- New chromene-based drug candidates for cancer treatment 2017
- Blocking glucose metabolism enhances the effect of HER inhibitors in cervical cancer therapy 2016
- Targeting glycolysis in acute myeloid leukemia: therapeutic applications. 2016
- Transport of short chain fatty acids and 3-bromopyruvate in cancer cells: implications for cancer therapy 2016
- Student success and perception of subject knowledge of an integrated course on the essentials of disease and treatment 2016
- An integrated course on the essential concepts of disease and treatment: longitudinal findings on acceptability and retention of disciplinary knowledge 2016
- Transport of monocarboxylic acids in cancer cells: implications of short chain fatty acids and 3-bromopyruvate for cancer therapy. 2016
- The clinicopathological significance of monocarboxylate transporters (MCTs) and CD147 in germ cell tumors 2016
- Internalization and cytotoxicity of zeolytes as carriers for celular delivery 2016
- Chromene derivatives as anticancer agents: synthesis and biological evaluation. 2016
- Internalization and cytotoxicity of zeolytes on breast cancer cell lines 2016
- The extracellular pH influences the cytotoxicity and transport of 3-Bromopyruvate in breast cancer cells 2016
- Effect of surface functionalization of zeolite L on cellular uptake in breast cancer and epithelial mammary cells 2016
- Lactate transport inhibition potentiates the cytotoxic effect of 5-fluorouracil in colorectal cancer cells. 2015
- Targeting lactate transport suppresses in vivo breast tumor growth 2015
- The Warburg effect:¿a new relevant road in the biology of adrenocortical tumors in adults 2015
- The metabolic microenvironment of melanomas: prognostic value of MCT4 2015
- Increased expression of monocarcboxylate transporters 1 and 4 and carbonic anhydrase IX in pancreatic ductal adenocarcinomas 2015
- Cathepsin D is involved in the degradation of damaged mitochondria during acetate-induced apoptosis in colorectal cancer cells. 2015
- Learning bacterial identification in infectious disease using a laboratory guided discovery approach 2015
- Monocarboxylate Transporter 1 (MCT1) expression at hypoxic conditions in glioblastomas: functional role and regulation 2015
- The Warburg effect: a new relevant road in the biology of adrenocortical tumors in adults 2015
- The metabolic coupling among urothelial bladder cancer compartments predicts tumour aggressiveness and chemoresistance 2015
- Anticancer profile of a selection of new chromene-based compounds 2015
- Cathepsin D protects colorectal cancer cells from acetate-induced apoptosis through autophagy-independent degradation of damaged mitochondria 2015
- Silencing of Monocarboxylate transporters as a tool to study the role of 3-bromopyruvate in breast cancer 2015
- Análise dos mecanismos de actividade biológica do própolis do Pereiro. 2014
- Caraterização da actividade antitumoral e angiogénica do própolis português usando modelos in vitro e in vivo. 2014
- Loss of caveolin-1 and gain of MCT4 expression in the tumour stroma: key events in the progression from an in situ invasive breast carcinoma 2013
- Multidrug resistance phenotype: pH regulation in breast cancer cells 2013
- An experimental study of 5-fluorouracil encapsulated in nanoporosity of zeolite structures as carriers for drug delivery 2013
- Drug delivery systems based on zeolites 2013
- Aberrant P-cadherin expression in breast câncer is associated with hypoxic, glycolytic and acid-resistant tumour phenotypes 2013
- CD147 and MCT1 – Potential partners in bladder cancer aggressiveness and chemoresistance 2013
- Characterization of the Antitumoral Activity of Portuguese Propolis. 2013
- Exploitation of Monocarboxylate Transporter 1 (MCT1) as target in breast cancer therapy 2013
- Loss of caveolin-1 and gain of MCT4 expression in the tumour stroma: key events in the progression from an in situ an invasive breast carcinoma 2013
- Monocarboxylate transporters as mediators in tumor-endothelial cell crosstalk 2013
- Potentiation of 5-fluorouracil entrapped in zeolite as drug delivery systems for in vitro models of coloretal and breast carcinomas 2013
- The effect of MCT1 and MCT4 downregulation on prostate cancer survival and aggressiveness 2013
- Contribution of Monocarboxylate Transporters to the Aggressive Phenotype of Breast Cancer 2013
- Targeting CD147/Basigin sensitizes A549 lung carcinoma cells to Phenformin 2013
- Targeting CD147/Basigin sensitizes A549 lung carcinoma cells to Phenformin. 2013
- Zeolites as suitable Drug Delivery Systems for anticancer drugs in in vitro models of colorectal carcinoma 2013
- Monocarboxylate Transporters as therapeutic targets in breast cancer. 2013
- MCT1 plasma membrane expression is associated to hypoxic regions in glioblastomas 2012
- Metabolic phenotypes associated with distinct androgen-responsive conditions can be a valuable tool for diagnostic and therapeutic options in prostate cancer 2012
- Clinical impact of the metabolic phenotype of prostate cancer: role of monocarboxylate transportes (MCTs). 2012
- Portuguese propolis decreases PC-3 cell glycolytic metabolism 2012
- Enhancing 5-FU activity in colorectal carcinoma-derived cell lines: combination with monocarboxylate transporter inhibitors and encapsulation into zeolites 2012
- Exploring the “Warburg effect” for cancer therapy: targeting lactate transport in cervical cancer 2012
- Regulation of the metabolic profile of breast cancer cells by hypoxia 2012
- Role of glioblastoma cell metabolism in response to anti-RTK therapy. 2012
- Role of monocarboxylate transporters (MCTs) in the regulation of the metabolic profile of cervical cancer cells by hypoxia. 2012
- Tracing the metabolic profile of prostate cancer progression. Roles for monocarboxylate transporters (MCTs) in prostate cancer metabolism 2012
- Zeolites: Promising candidates for drug delivery systems (DDSs). 2012
- Drug delivery systems for colorectal carcinoma treatment based on zeolites: a promising material 2012
- Aberrant expression of the CSC marker P-cadherin is associated with hypoxic/ glycolytic and acid resistant phenotype in breast carcinomas 2012
- Butyric acid increases monocarboxylate transportes (MCT) expression and enhances the cytotoxicity of the anti-tumoral agent 3-bromopyruvate (3-BP) in breast cancer cells. 2012
- Dissecting the role of glioblastoma cell metabolism in response to imatinib. 2012
- Exploiting metabolic alterations in prostate cancer diagnosis and prognosis. 2012
- Molecular mechanisms underlying multidrug resistance in cancer cell lines: targeting cell metabolism and pH regulation 2012
- Targeting CD147/Basigin in A549 lung carcinoma sensitizes these cells to Metformin 2012
- 3-bromopyruvate cytotoxic effect in breast cancer cells is dependent of monocarboxylate transporters (MCT) expression and is enhanced by butyrate 2012
- Effect of efflux pumps expression and cell bioenergetics in the multidrug resistance phenotype in cancer cells 2012
- Search for Portuguese propolis antimicrobial activity in a wide range of microorganisms. 2011
- Search for bioactivities in Portuguese propolis 2011
- CD147 immunohistochemistry discriminates between reactive mesothelial cells and malignant mesothelioma 2011
- Exploitating of Monocarboxylate transporters as therapeutic targets in lung cancer. 2011
- Inhibition of glycolytic metabolism decreases the aggressiveness behavior of breast cancer cells 2011
- Prostate cancer: exploitation of monocarboxylate transporters as potential therapeutic targets 2011
- Portuguese Propolis Inhibits Tumor Cell Glycolytic Metabolism 2011
- Anticancer drugs encapsulated in zeolites. 2011
- Assessment of monocarboxylate transporters 1 and 4, CD147, CD44 and MDRI could help to predict biochemical recurrence in prostate cancer 2011
- Bioactivities of Portuguese Propolis 2011
- CD147 overexpression allows an accurate discrimination of bladder cancer patients’ prognosis. 2011
- Monocarboxylate transporters as potential therapeutic targets in glioblastomas. 2011
- Monocarboxylate transporters – new molecular targets for colorectal carcinoma? 2011
- Portuguese Propolis Inhibits Glycolytic Metabolism in the Colon Cancer Cell Line HCT-15 2011
- Quercetin induces lactate transport inhibition in breast cancer cell lines 2011
- Role of Monocarboxylate transporters in Angiogenesis. 2011
- The role of Monocarboxylate transporters in lung cancer 2011
- Comparison of metabolic pathways between cancer and stromal cells in prostate carcinoma. A role of monocarboxylate transporters (MCTs) in tumour-stroma crosstalk. 2011
- Emerging roles for monocarboxylate transporters in prostate cancer metabolism. 2011
- Monocarboxylate transporters as new attractive targets for colorectal carcinoma therapy. 2011
- Monocarboxylate transporters as therapeutic targets in lung cancer. 2011
- Targeting lactate transport activity in gliomas 2011
- Treatment with Quercetin and Lonidamine decrease the aggressiveness behaviour of human breast cancer cells. 2011
- Inhibition of monocarboxylate transporter 1 in cervical cancer cells: effect of alpha-cyano-4-hydroxycinnamate and siRNA. 2010
- Monocarboxylate transporter 1 as a potential therapeutic target in glioblastomas. 2010
- Targeting lactate transport in breast cancer cells: an attractive metabolic approach to fight cancer? 2010
- Modulation of DNA Damage Prevention and Signaling Pathways in Diet Induced Colon Cancer Prevention. 2010
- Association of Toll-like receptor 9 (TLR9) T-1237C gene polymorphism with breast cancer susceptibilitiy and prognosis 2010
- GLUT1 and CAIX expression profile in breast cancer correlate with MCT1 overexpression. 2010
- Is dietary modulation of DNA repair involved in colon cancer prevention? 2010
- Effect of oxamic acid on different breast carcinoma cell lines. 2010
- MCT1 and its chaperone CD147 are upregulated in glioblastomas. 2010
- Monocarboxylate transporter 2 as putative prostate cancer marker. 2010
- Sensitivity of breast cancer cells to CHC, an inhibitor of monocarboxylate transporter 1 2010
- DNA damage as a biomarker of exposure to alkylating agents: Dietary chemoprevention of colon cancer through induction of MGMT 2009
- The prognostic value of monocarboxylate transporters in gastric cancer 2009
- O ácido alfa-ciano-4-hidroxicinâmico (CHC) potencia o efeito citotóxico do 5-FU em linhas celulares de carcinoma do cólon 2009
- Monocarboxylate transporters 2 and 4 are upregulated in prostate cancer 2009
- Possible alternative therapies to chronic laryngitis and laryngeal cancer: the use of COX-2 specific inhibitors. 2009
- Potencial terapêutico de inibidores de MCTs em Glioblastomas 2009
- The prognostic value of CD147/EMMPRIN is associated with monocarboxylate transporter 1 co-expression in gastric cancer 2009
- CD147 expression correlates with monocarboxylate transporters 1 and 4 in cervical carcinoma 2008
- Increased apoptosis in gastric carcinogenesis progression can be influenced by mechanisms involved in tumoral microenvironment pH control. 2008
- Monocarboxylate transporter 1 (MCT1) overexpression is associated with poor prognosis in breast carcinomas 2008
- Detection of Lymphatic Vessel Density by D2-40 in Ductal Invasive Breast Carcinomas. 2008
- Monocarboxylate transporter expression correlates with CD147 and HIF-1a in gastric cancer 2008
- MCT1 is upregulated in ER negative breast carcinomas. 2008
- Altered expression of monocarboxylate transporters in pre-invasive and invasive lesions of the uterine cervix. 2007
- Altered expression of monocarboxylate transporters 1, 2 and 4 in colorectal carcinomas 2007
- Monocarboxylate transporters as new targets for colorectal cancer therapy? 2007
- Changes in the expression of inflammatory mediators and tumoral markers folowing neurogenic laryngitis: therapeutic trial with Etoricoxib 2007
- Changes in the Expression of Inflammatory Mediators following Neurogenic Laryngitis: therapeutic trial with etoricoxib 2006
- Chronic Neurogenic Inflammation and Laryngeal Cancer: possible chemoprevention effect of selective COX-2 inhibitors 2006
- Imunohistochemical expression of VEGF-A and its ligands in non neoplastic lesions of the breast: correlation with dynamic angiothermography results 2006
- Lymphatic vessel density in HPV-induced intraepithelial cervical lesions. 2006
- Expression of the pro-inflammatory molecule COX-2 in different histological subtypes of cervix carcinomas: correlation with EGFR 2006
- Possible alternative therapies to chronic laryngitis and laryngeal cancer: the use of COX-2 specific inhibitors and detection of tumoral markers 2006
- Recurrent EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. 2006
- Os inibidores da COX-2 podem ser importantes no tratamento da laringite crónica 2006
- Análise de alterações genéticas preditivas da resposta à terapêutica dirigida ao alvo molecular EGFR em carcinomas metaplásicos da mama 2005
- Análise de alterações genéticas preditivas da resposta à terapêutica dirigida ao alvo molecular EGFR em tumores de bexiga 2005
- Expressão de COX-2 e papel dos inibidores de COX na cistite hemorrágica induzida por ifosfamida e seu metabolito acroleína 2005
- Expressão de COX-2 e papel dos inibidores de COX na cistite hemorrágica (CH) induzida por ifosfamida (IFS) e seu metabolito acroleína (ACR) 2005
- Effects of heavy metals on mycelial growth, thiol content and protein secretion in the aquatic fungus Fontanospora fusiramosa 2003
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