publicações selecionadas
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artigo académico
- Golgi a-mannosidase: opposing structures of Drosophila melanogaster and novel human model using molecular dynamics simulations and docking at different pHs. Journal of Biomolecular Structure & Dynamics. 2023
- Synthesis of Dehydrodipeptide and N-ethyl-dehydrodipeptide Derivatives with an α-Aminoisobutyric Acid Residue. Current Chemical Biology. 2015
- Synthesis and electrochemical behaviour of ß-halodehydroamino acid derivatives. Amino Acids. 2010
- Comparative effect of N-substituted dehydroamino acids and alpha-tocopherol on rat liver lipid peroxidation activities.. Journal of Enzyme Inhibition and Medicinal Chemistry. 2009
- Mild Two-Step Conversion of Primary Amides to Alcohols by Reduction of Acylimidodicarbonates with Sodium Borohydride. Synlett. 2003
- Synthesis of non-natural amino acids from N-(p-tolylsulfonyl)-a,ß-didehydroamino acid derivatives. European Journal of Organic Chemistry. 2003
- Reductive cleavage of N-substituted aromatic amides as tert-butyl acylcarbamates. Journal of the Chemical SocIETy-Perkin Transactions 1. 2002
- Michael addition of thiols, carbon nucleophiles and amines to dehydroamino acid and dehydropeptide derivatives. Journal of the Chemical SocIETy-Perkin Transactions 1. 2001
- Mild reductive cleavage of tryptophan and histidine side-chain protecting groups. European Journal of Organic Chemistry. 2001
- Cyclic voltammetry studies on substituted arenesulfonhydrazides. Journal of Chemical Research. 2000
- Novel aziridine esters by the addition of aromatic nitrogen heterocycles to a 2H-azirine-3-carboxylic ester. Tetrahedron Letters. 2000
- Synthesis of novel ß-substituted a,ß-dehydroamino acid derivatives. Tetrahedron Letters. 2000
- High yielding synthesis of dehydroamino acid and dehydropeptide derivatives. Journal of the Chemical SocIETy-Perkin Transactions 1. 1999
- Efficient synthesis of dehydroamino acid derivatives. Tetrahedron Letters. 1998
- Synthesis and cathodic cleavage of a set of substituted benzene-sulfonamides including the corresponding tert-butyl sulfonyl-carbamates: pKa of sulfonamides. Journal of the Chemical SocIETy-Perkin Transactions 1. 1995
- The use of electrochemical methods for deprotection during peptide synthesis. Review of Clinical Pharmacology and Pharmacokinetics, International Edition. 1995
- Selective cathodic cleavage of unsymmetrical imidodicarbonates, acylcarbamates and diacylamides. Journal of the Chemical SocIETy, Perkin Transactions 2. 1993
- Selective cathodic cleavage of protected, mixed primary-secondary amines. Journal of Chemical Research. 1991
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artigo de revista
- Effects of the Reactive Moiety of Phenolipids on Their Antioxidant Efficiency in Model Emulsified Systems. Antibiotics. 2021
- Interfacial Concentrations of Hydroxytyrosol Derivatives in Fish Oil-in-Water Emulsions and Nanoemulsions and Its Influence on Their Lipid Oxidation: Droplet Size Effects. Antibiotics. 2020
- Influence of AO chain length, droplet size and oil to water ratio on the distribution and on the activity of gallates in fish oil-in-water emulsified systems: Emulsion and nanoemulsion comparison. Food Chemistry. 2020
- An efficient one-pot synthesis of polyphenolic amino acids and evaluation of their radical-scavenging activity. Bioorganic Chemistry. 2019
- Control of antioxidant efficiency of chlorogenates in emulsions: modulation of antioxidant interfacial concentrations. Journal of the Science of Food and Agriculture. 2019
- Toxicity and structure-activity relationship (SAR) of a,ß-dehydroamino acids against human cancer cell lines. Toxicology in Vitro. 2018
- Synthesis and preliminary biological evaluation of new phenolic and catecholic dehydroamino acid derivatives. Tetrahedron. 2017
- Synthesis of N-alkyl-Ca,a-dimethylglycine derivatives. Arkivoc. 2014
- Synthesis and photophysical studies of new pyrenylamino acids. Tetrahedron. 2013
- Synthesis of Fluorescent Alanines by a Rhodium-Catalysed Conjugate Addition of Arylboronic Acids to Dehydroalanine Derivatives. European Journal of Organic Chemistry. 2013
- High yielding synthesis of N-ethyl dehydroamino acids. Amino Acids. 2012
- Electrochemical reduction of dehydroamino acids: Synthesis and photophysical properties of ß,ß-diarylalanines. Tetrahedron. 2011
- Synthesis of new N-ethyl dehydroamino acid derivatives: N-ethyl ß,ß-dibromo, N-ethyl ß-bromo ß-substituted, and N-ethyl ß,ß-disubstituted N-protected dehydroamino acid methyl esters. European Journal of Organic Chemistry. 2011
- A mild high yielding synthesis of oxazole-4-carboxylate derivatives. Tetrahedron. 2010
- Synthesis of novel nonproteinogenic amino acids: N-ethyl-a,ß- dehydroamino acid methyl esters. European Journal of Organic Chemistry. 2010
- Synthesis of bis-amino acid derivatives by Suzuki cross-coupling, Michael addition and substitution reactions. Amino Acids. 2009
- Pyrenylamino Acids: Synthesis, Photophysical and Electrochemical Studies. European Journal of Organic Chemistry. 2008
- Synthesis of Substituted Oxazoles fromN-Acyl-ß-hydroxyamino Acid Derivatives. European Journal of Organic Chemistry. 2008
- Reactivity of Dehydroamino Acids and Dehydrodipeptides TowardsN-Bromosuccinimide: Synthesis of ß-Bromo- and ß,ß-Dibromodehydroamino Acid Derivatives and of Substituted 4-Imidazolidinones. European Journal of Organic Chemistry. 2007
- Synthesis and Reactivity of ß-Bromo-ß-Substituted Dehydroalanines. European Journal of Organic Chemistry. 2006
- Synthesis of pure stereoisomers of benzo[b]thienyl dehydrophenylalanines by Suzuki cross-coupling. Preliminary studies of antimicrobial activity. Tetrahedron. 2004
- Synthesis and reactivity of a 1,4-dihydropyrazine derivative. Tetrahedron. 2004
- Electrochemical synthesis of diaminodicarboxylic acid derivatives. Tetrahedron Letters. 2003
- Synthesis of non-proteinogenic amino acids from N-(4-toluenesulfonyl)dehydroamino acid derivatives. Tetrahedron Letters. 2002
- Synthesis of 2,3,5-substituted pyrrole derivatives. Tetrahedron Letters. 2002
- Enhancing Reductive Cleavage of Aromatic Carboxamides. Organic Letters. 2001
- Synthesis of ß-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives. Journal of the Chemical SocIETy-Perkin Transactions 1. 2000
- High yielding synthesis of heterocyclic ß-substituted alanine derivatives. Tetrahedron Letters. 1999
- 2-Naphthalenesulfonyl as a tosyl substitute for protection of amino functions. Cyclic voltammetry studies on model sulfonamides and their preparative cleavage by reduction. Journal of Organic Chemistry. 1999
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capítulo de livro
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documento
- Correlations between Antioxidant Activity, Distribution, and Chemical Properties of Phenolic Compounds in O/W Model Emulsions 2020
- A. Esteves, M. Costa, F. Paiva-Martins, S. Losada-Barreiro, C. Bravo-Díaz, L.S. Monteiro, “Distribuição e atividade antioxidante do hidroxitirosol e seus ésteres em sistemas emulsionados”, 25º Encontro galaico-Português de Química, Santiago de Compostela, Espanha, 20 a 22 de novembro de 2019. 2019
- A. Lopes, L.S. Monteiro, F. Paiva-Martins, "Synthesis of novel cell-penetrating antioxidant peptides targeting the mitochondria”, 4th Symposium on Medicinal Chemistry, Universidade do Minho, Braga, Portugal, 24 de maio de 2019. 2019
- C. Ribeiro, S. Fernandes, A. Esteves, L. S. Monteiro, A. Santos-Silva, C. Catarino, F. Paiva-Martins, "Synthesis of olive phenolic compounds sulfate metabolites and their activity against red blood cells oxidative injury”, EuroFoodChem XX Conference, Porto, Portugal, 17 a 19 de junho de 2019. 2019
- D. Costa, L.S. Monteiro "Establishment of the ideal synthetic conditions for cell-penetrating antioxidant peptides targeting the mitochondria”, 4th Symposium on Medicinal Chemistry, Universidade do Minho, Braga, Portugal, 24 de maio de 2019. 2019
- F. Paiva-Martins, C. Ribeiro, S. Fernandes, L.S. Monteiro, A. Santos Silva, C. Catarino “Protective Activity of Olive Phenolic Compounds Sulfate Metabolites against Red Blood Cells Oxidative Injury”, 17th Euro Fed Lipid Congress, Sevilha, Espanha, 20 a 23 de outubro de 2019. 2019
- F. Paiva-Martins, M. Costa, S. Oliveira, I. Machado, L.S. Monteiro "An efficient one-pot synthesis of polyphenolic amino acids and evaluation of their radical-scavenging activity”, Vº Encontro de Técnicas de Caracterização e Análise Química, Universidade do Minho, Braga, 4 de maio de 2018. 2018
- I. Machado, M. Azevedo, S. Oliveira, L.S. Monteiro "Synthesis of N-catechoyl phenylalanine and dehydrophenylalanine derivatives”, 3rd Symposium on Medicinal Chemistry, Universidade do Minho, Braga, Portugal, 26 de maio de 2017. 2017
- J. Parente, L.S. Monteiro, S. Oliveira, F. Paiva-Martins "Synthesis of phenolic and catecholic amino acids by Michael addition to a dehydroalanine derivative”, 3rd Symposium on Medicinal Chemistry, Universidade do Minho, Braga, Portugal, 26 de maio de 2017. 2017
- L.S. Monteiro, S. Oliveira, F. Paiva-Martins "Synthesis of phenolic and catecholic amino acids by the modified multicomponent Ugi reaction”, 3rd Symposium on Medicinal Chemistry, Universidade do Minho, Braga, Portugal, 26 de maio de 2017. 2017
- S. Oliveira, L.S. Monteiro, P.M.T. Ferreira, F. Paiva-Martins "Synthesis of the methyl esters of N-phenoyl and N-catechoyl dehydroalanine and dehydrophenylalanine”, 3rd Symposium on Medicinal Chemistry, Universidade do Minho, Braga, Portugal, 26 de maio de 2017. 2017
- S. Oliveira, F. Paiva-Martins, P.M.T. Ferreira, L.S. Monteiro, "Synthesis of dehydroamino acid derivatives with potential antioxidante activity”, Terceiro Simpósio Ibero-americano de Química Orgânica, Universidade do Porto, Porto, Portugal, 23 a 26 de setembro de 2016. 2016
- J. Lopes, L.S. Monteiro, S. P. Lima "Synthesis of dipeptides with alpha,alpha-disubstituted dehydroalanine and Ca,a-dimethylglycine residues”, Congresso de Química Orgânica e Química Terapêutica, Universidade do Porto, Porto, Portugal, 1 a 3 de dezembro de 2015. 2015
- S. Oliveira, L.S. Monteiro, P.M.T. Ferreira "Synthesis of a new fluorescent oxazole derivative from threonine”, 2nd Symposium on Medicinal Chemistry, Universidade do Minho, Braga, Portugal, 8 de maio de 2015. 2015
- L.G. Fantinati, M. Szewczyk, M.S. Gonçalves, L.S. Monteiro "Sulfonamidas como grupos protetores de aminoácidos: clivagem eletroquímica", IIIº Encontro de Técnicas de Caracterização e Análise Química, Universidade do Minho, Braga, 6 de junho de 2014. 2014
- N. Machado, S. Pereira, L. S. Monteiro, S. Pereira-Lima "Efficient N-Alkylation of Ca,a-dimethylglycine derivatives”, 1st Symposium on Medicinal Chemistry, Universidade do Minh, Braga, Portugal, 17 de maio de 2013. 2013
- L.S. Monteiro, Cláudia Barroso "Synthesis of N-ethyl ß,ß-diaryldehydroalanine and N-ethylindole derivatives”, Universidade do Porto, Porto, Portugal, 9 a 11 de maio de 2012. 2012
- Electrochemical reduction of ß-aryldehydroamino acid derivatives 2011
- L.S. Monteiro, J.J. Andrade, A.C. Suárez "Synthesis of new N-ethyl dehydroamino acids”, 9º Encontro Nacional de Química Orgânica, Universidade do Minho, Braga, Portugal, 3 a 6 de julho de 2011. 2011
- Synthesis of novel non-proteinogenic amino acids: N-ethyldehydroamino acids 2011
- G. Pereira, P.M.T. Ferreira, L.S. Monteiro, E.M.S. Castanheira, H. Vilaça "High yielding synthesis of oxazole-4-carboxylates from dehydroamino acid derivatives. Application as fluorescent markers for peptides”, 31st European Peptide Symposium, Copenhaga, Dinamarca, 5 a 9 de setembro de 2010. 2010
- H. Vilaça, G. Pereira, P.M.T. Ferreira, L.S. Monteiro, “Synthesis of new bis-amino acid derivatives”, 46th International Conference on Medicinal Chemistry, Reims, França, 30 de junho a 2 de julho de 2010. 2010
- L.S. Monteiro, J. Kolomanska, A.C. Suárez "Synthesis of N-EthyLated non-proteinogenic amino acids: N-ethyldehydroamino acids and N-ethyl, ß-heterocyclic amino acids”, 2nd National Meeting on Medicinal Chemistry, Universidade de Coimbra, Portugal, 28 a 30 de novembro de 2010. 2010
- L.S. Monteiro, J. Kolomanska, A.C. Suárez "Synthesis of novel non-proteinogenic amino acids: N-ethyldehydroamino acids”, 31st European Peptide Symposium, Copenhaga, Dinamarca, 5 a 9 de setembro de 2010. 2010
- P.A.M. Pereira, L.S. Monteiro "Valorização Económica de Subprodutos da Indústria Corticeira", Iº Encontro de Técnicas de Caracterização e Análise Química, Universidade do Minho, Braga, 7 de maio de 2010. 2010
- P.M.T. Ferreira, L.S. Monteiro, G. Pereira, C. Lopes "Electrochemical reduction of ß-aryldehydroamino acid derivatives”, 31st European Peptide Symposium, Copenhaga, Dinamarca, 5 a 9 de setembro de 2010. 2010
- P.M.T. Ferreira, L.S. Monteiro, G. Pereira, C. Lopes "Electrochemical synthesis of the E-isomer of ß-substituted dehydroamino acid derivatives”, 46th International Conference on Medicinal Chemistry, Reims, França, 30 de junho a 2 de julho de 2010. 2010
- P.M.T. Ferreira, E.M.S. Castanheira, L.S. Monteiro, G. Pereira "Synthesis of new fluorescent amino acids” Esoc 2009: 16th European Symposium on Organic Chemistry, Praga, Republica Checa, 12 a 16 de julho de 2009. 2009
- P.M.T. Ferreira, L.S. Monteiro, G. Pereira "Synthesis of substituted oxazoles from N-acyldehydroamino acids", 23rd European Colloquium on Heterocyclic Chemistry, Universidade de Antuerpia, Antuerpia, Belgica, 9 a 13 de setembro de 2008. 2008
- P.M.T. Ferreira, L.S. Monteiro, G. Pereira "Reactivity of dehydroamino acid derivatives towards N-bromo and N-iodosuccinimide", 7º Encontro Nacional de Química Orgânica, Fundação Calouste Gulbenkian, Lisboa, 16 a 18 de julho de 2007. 2007
- P.M.T. Ferreira, L.S. Monteiro, G. Pereira, L. Silva "O-(tert-Butyloxycarbonyl) hydroxyamino acids: synthesis and reactivity", 11th European Symposium on Organic Reactivity, Universidade do Algarve, Faro, Portugal, 1 a 6 de julho de 2007. 2007
- P.M.T. Ferreira, M.J.R.P. Queiroz, L.S. Monteiro, “Synthesis of bis-dehydroamino acid derivatives by a palladium catalysed bis-coupling”, The 10th Kyoto International Conference on New Aspects of Organic Chemistry, Kyoto, Japão, 13 a 17 de novembro de 2006. 2006
- New tryptophan and histidine side chain protecting groups 2005
- P.M.T. Ferreira, L.S. Monteiro, "Synthesis of a-alkylaminoglycines", 10th European Symposium on Organic Reactivity, Universidade de Roma, Roma, Itália, 25 a 30 de julho de 2005. 2005
- P.M.T. Ferreira, L.S. Monteiro, J. Sacramento, "Synthesis of imidazolidinones from dehydropeptides", 9th International Congress on Amino Acids and Proteins, Viena, Austria, 8 a 12 de agosto de 2005. 2005
- Synthesis and reactivity of N,N-bis-(tert-butyloxy-carbonyl)-2,5-bis-methoxycarbonyl-1,4-dihydropyrazine 2005
- H.L.S. Maia, L.S. Monteiro, J. Sebastião, "New tryptophan and histidine side chain protecting groups", 8th International Symposium on Solid Phase Synthesis and Combinatorial Libraries, Imperial College, Londres, Reino Unido, 2 a 6 de setembro de 2003. 2003
- P.M.T. Ferreira, L.S. Monteiro, "Synthesis and reactivity of N,N-bis-(tert-butyloxycarbonyl)-2,5-bis-methoxycarbonyl-1,4-dihydropyrazine", 8th International Symposium on Solid Phase Synthesis and Combinatorial Libraries, Imperial College, Londres, Reino Unido, 2 a 6 de setembro de 2003. 2003
- Synthesis of non-proteinogenic amino acids from N-(4-toluenesulfonyl)dehydroalanine derivatives 2003
- A.S. Abreu, N.O. Silva, L.S. Monteiro, M.J.R.P. Queiroz, P.M.T. Ferreira, "Síntese de derivados de aminoácidos contendo benzo[b]tiofenos por acoplamento de Suzuki", 18º Encontro Nacional da Sociedade Portuguesa de Química, Universidade de Aveiro, Aveiro, 25 a 27 de março de 2002. 2002
- Michael additions to dehydroalanine derivatives 2002
- Synthesis of ß-benzo[b]thiophene dehydroamino acids by palladium catalyzed reactions 2002
- N. Silva, A.S. Abreu, P.M.T. Ferreira, L.S. Monteiro, M.J.R.P. Queiroz, "Synthesis of sulfur analogues of dehydrotryptophan by Suzuki palladium catalyzed cross coupling", 4º Encontro Nacional de Química Orgânica, Universidade de Coimbra, Coimbra, 26 a 28 de setembro de 2001. 2001
- P.M.T. Ferreira, H.L.S. Maia, L.S. Monteiro, J. Sacramento, "Michael additions to dehydroalanine derivatives", 2nd International Peptide Symposium/17th American Peptide Symposium, San Diego, Estados Unidos, 9 a 14 de junho de 2001. 2001
- P.M.T. Ferreira, H.L.S. Maia, L.S. Monteiro, J. Sacramento, Synthesis of ß-substituted dehydroamino acids and 2,3-dihydrofurans", 4º Encontro Nacional de Química Orgânica, Universidade de Coimbra, Coimbra, 26 a 28 de setembro de 2001. 2001
- P.M.T. Ferreira, H.L.S. Maia, L.S. Monteiro, M.J.R.P. Queiroz, N. Silva, "Synthesis of ß-benzo[b]thiophene dehydro-amino acids by palladium catalyzed reactions", 2nd International Peptide Symposium/17th American Peptide Symposium, San Diego, Estados Unidos, 9 a 14 de junho de 2001. 2001
- High yield synthesis of heterocyclic ß-substituted alanine derivatives 2000
- Efficient preparation of dehydroalanine derivatives 1999
- M.J. Alves, P.M.T. Ferreira, T.L. Gilchrist, H.L.S. Maia, L.S. Monteiro, "Reactions of methyl 2-(2,6-dichlorophenyl)-2H-azirine 3-carboxylate with heteroaromatic systems incorporating an NH unit", 3º Encontro Nacional de Química Orgânica, Universidade da Beira Interior, Covilhã, 23 a 25 de junho de 1999. 1999
- P.M.T. Ferreira, H.L.S. Maia, L.S. Monteiro, "High yield synthesis of heterocyclic ß-substituted alanine derivatives", 16th American Peptide Symposium, Minneapolis, Estados Unidos, 26 de junho a 1 de julho de 1999. 1999
- P.M.T. Ferreira, H.L.S. Maia, L.S. Monteiro, J. Sacramento, "Síntese de dipéptidos contendo alaninas ß-heterocíclicas", 3º Encontro Nacional de Química Orgânica, Universidade da Beira Interior, Covilhã, 23 a 25 de junho de 1999. 1999
- Preparative dehydration of serine and threonine in peptides 1999
- Stereoselective synthesis of dehydroaminobutyric acid 1999
- Efficient preparation of Na-alkylated amino acid and peptide derivatives via redox alkylation of suitable N-tosylated intermediates 1998
- P.M.T. Ferreira, H.L.S. Maia, L.S. Monteiro, "Preparative dehydration of serine and threonine in peptides", 25th European Peptide Symposium, Budapeste, Hungria, 30 de agosto a 4 de setembro de 1998. 1998
- P.M.T. Ferreira, H.L.S. Maia, L.S. Monteiro, "Efficient preparation of dehydroalanine derivatives", 1st International Peptide Symposium, Quioto, Japão, 30 de novembro a 5 de dezembro de 1997. 1997
- P.M.T. Ferreira, H.L.S. Maia, L.S. Monteiro, "Stereoselective synthesis of dehydroaminobutyric acid", 1st International Peptide Symposium, Quioto, Japão, 30 de novembro a 5 de dezembro de 1997. 1997
- C. Athanassopoulos, H.L.S. Maia, L.S. Monteiro, D. Papaioannou, "Efficient preparation of Na-alkylated amino acid and peptide derivatives via redox alkylation of suitable N-tosylated intermidiates", 24th European Peptide Symposium, Edimburgo, Reino Unido, 8 a 13 de setembro de 1996. 1996
- Cyclic thrombin receptor-derived peptide analogues containing D-Phe and D-Arg 1995
- D. Panagiotopoulos, J.M. Matsoukas, M. Keramida, D. Gatos, L.S. Monteiro, H.L.S. Maia, R. Yamgagni, Q. Wu, P. Redstone, G.J. Moore, A.A. Laniyonu, M. Saifeddine, M.D. Hollenberg, "Cyclic thrombin receptor-derived peptide analogues containing D-Phe and D-Arg", 23rd European Peptide Symposium, Braga, Portugal, 4 a 10 de setembro de 1994. 1994
- Facilitation of selective cathodic cleavage of amine protecting groups 1993
- P.M.T. Ferreira, H.L.S. Maia, L.S. Monteiro, L.M. Rodrigues, "Preparative selective cathodic cleavage of amine protecting groups", Biomed Euroworkshop 1993, Universidade de Patras, Grécia, 14 e 15 de outubro de 1993. 1993
- H.L.S. Maia, L.S. Monteiro, F. Degerbeck, L. Grehn, U. Ragnarsson, "Selective cathodic cleavage of diacylamides", 22nd European Peptide Symposium, Interlaken, Suiça, 13 a 18 de setembro de 1992. 1992
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teses