publicações selecionadas
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artigo académico
- Correction: Silva et al. Chemical Profile and Bioactivities of Extracts from Edible Plants Readily Available in Portugal. Foods 2021, 10, 673. Antibiotics. 2022
- Application of PEG400 in the one-pot synthesis of 7-[4-alkyl- or (hetero)aryl-1H-1,2,3-triazol-1-yl]thieno[3,2-b]pyridines via SNAr and Cu(I)-Catalyzed Azide-Alkyne Cycloaddition and preliminary evaluation of their anti-tumour activity. Tetrahedron Letters. 2020
- Carbon-Based Magnetic Nanocarrier for Controlled Drug Release: A Green Synthesis Approach. C. 2018
- Chemical characterization, antioxidant, anti-inflammatory and cytotoxic properties of bee venom collected in Northeast Portugal. Food and Chemical Toxicology. 2016
- Characterization of a Squaraine/Chitosan System for Photodynamic Therapy of Cancer. ACS Applied Polymer Materials. 2016
- Wild Roman chamomile extracts and phenolic compounds: enzymatic assays and molecular modelling studies with VEGFR-2 tyrosine kinase. Food Bioscience. 2016
- Folk medicinal plant extracts as a source of biomolecules with antifungal properties against Candida species 2015
- The use of different phenolic compounds rich extracts obtained from cultivated thyme for antioxidant and antibacterial purposes 2015
- Extensional flow-based microfluidic device: Deformability assessment of red blood cells in contact with tumor cells. Biochip Journal. 2014
- Antifungal activity against Candida species and phenolic characterization of decoction, infusion and hydroalcoholic extract of cultivated Salvia officinalis L.. Planta Medica. 2014
- Coprinopsis atramentaria extract, its organic acids, and synthesized glucuronated and methylated derivatives as antibacterial and antifungal agents. Food Bioscience. 2014
- Cytotoxicity of Coprinopsis atramentaria extract, organic acids and their synthesized methylated and glucuronate derivatives. Food Research International. 2014
- In vitro study of the antifungal potential of Glycyrrhiza glabra L. against Candida species. Planta Medica. 2014
- New insights into the effects of formulation type and compositional mixtures on the antioxidant and cytotoxic activities of dietary supplements based-on hepatoprotective plants. Food Bioscience. 2014
- Bioactivity of Different Enriched Phenolic Extracts of Wild Fruits from Northeastern Portugal: A Comparative Study. Plant Foods for Human Nutrition. 2013
- MOLA: a bootable, self-configuring system for virtual screening using AutoDock4/Vina on computer clusters. Journal of Cheminformatics. 2010
- QSAR model for predicting radical scavenging activity of di(hetero)arylamines derivatives of benzo[b]thiophenes. European Journal of Medicinal Chemistry. 2009
- Insights in the antioxidant activity of diarylamines from the 2,3-dimethylbenzo[b]thiophene through the redox profile. Electrochimica Acta. 2009
- Synthesis and antioxidant activity evaluation of new 7-aryl or 7-heteroarylamino-2,3-dimethylbenzo[b]thiophenes obtained by Buchwald-Hartwig C-N cross-coupling. Bioorganic & Medicinal Chemistry. 2007
- Synthesis and antimicrobial activity studies of ortho-chlorodiarylamines and heteroaromatic tetracyclic systems in the benzo[b]thiophene series. Bioorganic & Medicinal Chemistry. 2006
- Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophene series by free radical scavenging activity and reducing power. Bioorganic & Medicinal Chemistry Letters. 2006
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artigo de conferência
- Electrospun natural nanofibres with bioactive plant extracts for therapeutic applications 2019
- Bioactivity and phenolic characterization of different medicinal and aromatic plants 2019
- Multifunctional graphene-based magnetic nanocarriers optimized with copolymer Pluronic F127 for biomedical applications 2017
- Antimicrobial potential of Eucalyptus globulus against biofilms of Staphylococcus aureus isolated from bovine mastitis 2016
- Candidacidal potential of licorice phenolic extract: emphasis on its mode of action 2016
- Contribution of plant phytochemicals to organic homeostasis: focus on the aging process and opportunistic infections 2016
- Contribution of plant-derived phenolic compounds to combat Candida species biofilms 2016
- Magneto-sensitive liposomes containing manganese ferrite nanoparticles as nanocarriers for new promising antitumor thienopyridin-amine derivatives 2016
- Folk medicinal plant extracts as a source of biomolecules with antifungal properties against Candida species 2015
- Glycyrrhiza glabra L. as a promisor candidacidal in biofilms and planktonic cells: comparison between phenolic extract and isolated compounds 2015
- New approaches to the treatment of candidiasis regarding alternative and complementary medicine 2015
- Phenolic extracts of Fragaria vesca L. roots with anti-Candida potential: chemical characterization and in vitro antifungal capacity 2015
- The use of different phenolic compounds rich extracts obtained from cultivated thyme for antioxidant and antibacterial purposes 2015
- Eucalyptus globulus L. extract as an antifungal agent against Candida species 2014
- In vitro study of the antifungal potential of Apiaceae hydroalcoholic extracts against Candida species 2014
- In vitro study of the antifungal potential of Lamiaceae hydroalcoholic extracts against Candida species 2014
- New Di(hetero)arylethers and Di(hetero)arylamines in the Thieno [3,2-b]pyridine Series: Synthesis, Growth Inhibitory Activity on Human Tumor Cell Lines and Nanotumor Cells, Effects on Cell Cycle And on Apoptosis 2014
- New perspectives of Juglans regia L. phytochemicals against Candida species 2014
- Phenolic compounds in decoction, infusion and hydroalcoholic extract of cultivated thyme (Thymus vulgaris L.) with bioactive properties 2014
- Phytochemicals in Rubus ulmifolius Schott metanol/water extracts and its antifungal properties against Candida species 2014
- Synthesis, molecular docking and biological Evaluation of New 1-Aryl-3-[3-(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas as Potent Type II CEGFR-2 Tyrosine Kinase Inhibitors 2014
- Measurement of Red Blood Cells Deformation Índex in a Hyperbolic Microchannel 2013
- Antifungal activity of natural extracts from Northeastern Portuguese flowers against Candida biofilms 2012
- Cistus ladanifer as a source of phenolic compounds with antifungal activity 2012
- Natural extracts from wild flowers used in Portuguese folk medicine like a new antifungal agents against Candida species 2012
- Screening of the antibacterial activity of phenolic extracts from Portuguese north-eastern plants 2012
- Estudos de biodegradabilidade de corantes azo de aplicação têxtil por Phanerochaete chrysosporium 1999
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artigo de revista
- Magnetoliposomes Based on Magnetic/Plasmonic Nanoparticles Loaded with Tricyclic Lactones for Combined Cancer Therapy. Pharmaceutics. 2021
- Synthesis of Novel Methyl 7-[(Hetero)arylamino]thieno[2,3-b]pyrazine-6-carboxylates and Antitumor Activity Evaluation: Effects in Human Tumor Cells Growth, Cell Cycle Analysis, Apoptosis and Toxicity in Non-Tumor Cells. Biomolecules. 2021
- Chemical Profile and Bioactivities of Extracts from Edible Plants Readily Available in Portugal. Antibiotics. 2021
- Chitosan/nanocellulose electrospun fibers with enhanced antibacterial and antifungal activity for wound dressing applications. Reactive and Functional Polymers. 2021
- Satureja montana L. and Origanum majorana L. Decoctions: Antimicrobial Activity, Mode of Action and Phenolic Characterization. Antibiotics. 2020
- Magnetoliposomes Containing Calcium Ferrite Nanoparticles for Applications in Breast Cancer Therapy. Pharmaceutics. 2019
- Phenolic Plant Extracts Versus Penicillin G: In Vitro Susceptibility of Staphylococcus aureus Isolated from Bovine Mastitis. Pharmaceuticals. 2019
- Anti-biofilm activity of hydromethanolic plant extracts against Staphylococcus aureus isolates from bovine mastitis. Heliyon. 2019
- Cotton-hydrogel composite for improved wound healing: antimicrobial activity and anti-inflammatory evaluation - part 2. Polymers for Advanced Technologies. 2019
- A Tailor-Made Protocol to Synthesize Yolk-Shell Graphene-Based Magnetic Nanoparticles for Nanomedicine. C. 2018
- Plant phenolic extracts as an effective strategy to control Staphylococcus aureus , the dairy industry pathogen. Dyes and Pigments. 2018
- Multifunctional graphene-based magnetic nanocarriers for combined hyperthermia and dual stimuli-responsive drug delivery. Journal of Nanoparticle Research. 2018
- Magnetoliposomes as carriers for promising antitumor thieno[3,2-b]pyridin-7-arylamines: photophysical and biological studies. Nanoscale. 2017
- Magnetoliposomes as carriers for promising antitumor thieno[3,2-b]pyridin-7-arylamines: photophysical and biological studies. Nanoscale. 2017
- Susceptibility testing of Candida albicans and Candida glabrata to Glycyrrhiza glabra L.. Dyes and Pigments. 2017
- Bioactive properties and functional constituents of Hypericum androsaemum L.: A focus on the phenolic profile. Food Research International. 2016
- In vivo antioxidant activity of phenolic compounds: facts and gaps. Trends in Food Science and Technology. 2016
- A poly-e-caprolactone based biofilm carrier for nitrate removal from water. Amino Acids. 2016
- Antioxidant potential of two Apiaceae plant extracts: a comparative study focused on the phenolic composition. Dyes and Pigments. 2016
- In vitro anti-Candida activity of Glycyrrhiza glabra L.. Dyes and Pigments. 2016
- Bioactive Properties of Tabebuia impetiginosa-Based Phytopreparations and Phytoformulations: A Comparison between Extracts and Dietary Supplements. Biomolecules. 2015
- The powerful in vitro bioactivity of Euterpe oleracea Mart. seeds and related phenolic compounds. Dyes and Pigments. 2015
- The contribution of phenolic acids to the anti-inflammatory activity of mushrooms: Screening in phenolic extracts, individual parent molecules and synthesized glucuronated and methylated derivatives. Food Research International. 2015
- Chemical composition, antioxidant activity and bioaccessibility studies in phenolic extracts of two Hericium wild edible species. ACS Food Science & Technology. 2015
- Nutritional value, bioactive compounds and antioxidant properties of three edible mushrooms from Poland. Food Bioscience. 2015
- Folk medicinal plant extracts as a source of biomolecules with antifungal properties against Candida species. Chemotherapy: Open Access. 2015
- The use of different phenolic compounds rich extracts obtained from cultivated thyme for antioxidant and antibacterial purposes. Chemotherapy: Open Access. 2015
- Chemical features of Ganoderma polysaccharides with antioxidant, antitumor and antimicrobial activities. Phytochemistry. 2015
- Bioactivity of phenolic acids: Metabolites versus parent compounds: A review. Food Chemistry. 2015
- Chemical characterisation and bioactive properties of Prunus avium L.: The widely studied fruits and the unexplored stems. Food Chemistry. 2015
- Characterization of phenolic compounds and antioxidant properties of Glycyrrhiza glabra L. rhizomes and roots. Nanoscale. 2015
- Evaluation of bioactive properties and phenolic compounds in different extracts prepared from Salvia officinalis L.. Food Chemistry. 2015
- Activity of phenolic compounds from plant origin against Candida species. Dyes and Pigments. 2015
- Decoction, infusion and hydroalcoholic extract of cultivated thyme: Antioxidant and antibacterial activities, and phenolic characterisation. Food Chemistry. 2015
- In Vivo Anti-Candida Activity of Phenolic Extracts and Compounds: Future Perspectives Focusing on Effective Clinical Interventions.. Biomed Research International. 2015
- Is honey able to potentiate the antioxidant and cytotoxic properties of medicinal plants consumed as infusions for hepatoprotective effects?. Food Bioscience. 2015
- Plants used in folk medicine: The potential of their hydromethanolic extracts against Candida species. Dyes and Pigments. 2015
- Effects of gamma radiation on chemical and antioxidant properties, anti-hepatocellular carcinoma activity and hepatotoxicity of borututu. Innovative Food Science & Emerging Technologies. 2014
- Infusions and decoctions of Castanea sativa flowers as effective antitumor and antimicrobial matrices. Dyes and Pigments. 2014
- Decoction, infusion and hydroalcoholic extract of Origanum vulgare L.: Different performances regarding bioactivity and phenolic compounds. Food Chemistry. 2014
- Candidiasis: Predisposing Factors, Prevention, Diagnosis and Alternative Treatment. Mycopathologia. 2014
- Antifungal activity of phenolic compounds identified in flowers from North Eastern Portugal against Candida species. Antibiotics. 2014
- Antibacterial potential of northeastern Portugal wild plant extracts and respective phenolic compounds.. Biomed Research International. 2014
- Antioxidant activity of aminodiarylamines in the thieno[3,2-b]pyridine series: Radical scavenging activity, lipid peroxidation inhibition and redox profile. Journal of Enzyme Inhibition and Medicinal Chemistry. 2014
- Coprinopsis atramentaria extract, its organic acids, and synthesized glucuronated and methylated derivatives as antibacterial and antifungal agents. Food Bioscience. 2014
- Cytotoxicity of Portuguese Propolis: The Proximity of the In VitroDoses for Tumor and Normal Cell Lines. Biomed Research International. 2014
- New insights into the effects of formulation type and compositional mixtures on the antioxidant and cytotoxic activities of dietary supplements based-on hepatoprotective plants. Food Bioscience. 2014
- Synergisms in antioxidant and anti-hepatocellular carcinoma activities of artichoke, milk thistle and borututu syrups. Dyes and Pigments. 2014
- Two-Dimensional PCA Highlights the Differentiated Antitumor and Antimicrobial Activity of Methanolic and Aqueous Extracts ofLaurus nobilisL. from Different Origins. Biomed Research International. 2014
- Characterisation of phenolic compounds in wild fruits from Northeastern Portugal. Food Chemistry. 2013
- Leaves and decoction of Juglans regia L.: Different performances regarding bioactive compounds and in vitro antioxidant and antitumor effects. Dyes and Pigments. 2013
- New di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series: Synthesis, growth inhibitory activity on human tumor cell lines and non-tumor cells, effects on cell cycle and on programmed cell death. European Journal of Medicinal Chemistry. 2013
- Antimicrobial and demelanizing activity of Ganoderma lucidum extract, p-hydroxybenzoic and cinnamic acids and their synthetic acetylated glucuronide methyl esters. Food and Chemical Toxicology. 2013
- A comparative study of chemical composition, antioxidant and antimicrobial properties of Morchella esculenta (L.) Pers. from Portugal and Serbia. Food Research International. 2013
- 1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR-2 Tyrosine Kinase Inhibitors: Synthesis, Biological Evaluation, and Molecular Modelling Studies. Biomed Research International. 2013
- Antifungal activity and detailed chemical characterization of Cistus ladanifer phenolic extracts. Dyes and Pigments. 2013
- Antimicrobial activity, growth inhibition of human tumour cell lines, and phytochemical characterization of the hydromethanolic extract obtained from Sapindus saponaria L. aerial parts. Biomed Research International. 2013
- Antioxidant properties, anti-hepatocellular carcinoma activity and hepatotoxicity of artichoke, milk thistle and borututu. Dyes and Pigments. 2013
- Bioactivity and chemical characterization in hydrophilic and lipophilic compounds of Chenopodium ambrosioides L. Journal of Functional Foods. 2013
- Characterization of phenolic compounds in wild medicinal flowers from Portugal by HPLC-DAD-ESI/MS and evaluation of antifungal properties. Dyes and Pigments. 2013
- Infusion and decoction of wild German chamomile: Bioactivity and characterization of organic acids and phenolic compounds. Food Chemistry. 2013
- Nutrients, phytochemicals and bioactivity of wild Roman chamomile: A comparison between the herb and its preparations. Food Chemistry. 2013
- Suillus luteus methanolic extract inhibits cell growth and proliferation of a colon cancer cell line. Food Research International. 2013
- Phenolic, Polysaccharidic, and Lipidic Fractions of Mushrooms from Northeastern Portugal: Chemical Compounds with Antioxidant Properties. Journal of Agricultural and Food Chemistry. 2012
- Fruiting body, spores and in vitro produced mycelium of Ganoderma lucidum from Northeast Portugal: A comparative study of the antioxidant potential of phenolic and polysaccharidic extracts. Food Research International. 2012
- Aminodi(hetero)arylamines in the Thieno[3,2-b]pyridine Series: Synthesis, Effects in Human Tumor Cells Growth, Cell Cycle Analysis, Apoptosis and Evaluation of Toxicity Using Non-Tumor Cells. Biomolecules. 2012
- Selective Flexibility of Side-Chain Residues Improves VEGFR-2 Docking Score using AutoDock Vina. Chemical Biology & Drug Design. 2012
- Anti-hepatocellular carcinoma activity using human HepG2 cells and hepatotoxicity of 6-substituted methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate derivatives: In vitro evaluation, cell cycle analysis and QSAR studies. European Journal of Medicinal Chemistry. 2011
- ChemT, an open-source software for building template-based chemical libraries. SAR and QSAR in Environmental Research. 2011
- Synthesis of the first thieno-d-carboline. Fluorescence studies in solution and in lipid vesicles. Journal of Photochemistry and Photobiology A-Chemistry. 2006
- Synthesis of ß-Benzo[b]thienyldehydrophenylalanine Derivatives by One-Pot Palladium-Catalyzed Borylation and Suzuki Coupling (BSC) and Metal-Assisted Intramolecular Cyclization - Studies of Fluorescence and Antimicrobial Activity. European Journal of Organic Chemistry. 2005
- Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series: a structure-activity evaluation study. Bioorganic & Medicinal Chemistry Letters. 2004
- Synthesis of pure stereoisomers of benzo[b]thienyl dehydrophenylalanines by Suzuki cross-coupling. Preliminary studies of antimicrobial activity. Tetrahedron. 2004
- Palladium-Catalysed Amination of Electron-Deficient or Relatively Electron-Rich Benzo[b]thienyl Bromides- Preliminary Studies of Antimicrobial Activity and SARs. European Journal of Organic Chemistry. 2004
- Palladium-catalyzed amination and cyclization to heteroannellated indoles and carbazoles. Tetrahedron. 2003
- Photochemistry and photophysics of thienocarbazoles. Photochemistry and Photobiology. 2003
- Synthesis of diarylamines in the benzo[b]thiophene series bearing electron donating or withdrawing groups by Buchwald-Hartwig C-N coupling. Tetrahedron. 2003
- Tandem palladium-catalyzed borylation and Suzuki coupling (BSC) to thienocarbazole precursors. Tetrahedron Letters. 2003
- Novel synthetic routes to thienocarbazoles via palladium or copper catalyzed amination or amidation of arylhalides and intramolecular cyclization. Tetrahedron. 2002
- Biodegradation of bioaccessible textile azo dyes by Phanerochaete chrysosporium. Antibiotics. 2001
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capítulo de livro
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documento
- Magnetic/plasmonic liposomes as nanocarriers for novel antitumor tricyclic lactones against non-small cell lung cancer 2020
- Bioactivity and phenolic characterization of different medicinal and aromatic plants 2019
- Multifunctional graphene-based magnetic nanocarriers optimized with copolymer Pluronic F127 for biomedical applications 2017
- Optimization of carbon-based magnetic drug nanocarriers synthesized by green routes 2017
- Magneto-sensitive liposomes containing manganese ferrite nanoparticles as nanocarriers for new promising antitumor thienopyridin-amine derivatives 2016
- Antimicrobial potential of Eucalyptus globulus against biofilms of Staphylococcus aureus isolated from bovine mastitis 2016
- Contribution of plant-derived phenolic compounds to combat Candida species biofilms 2016
- Glycyrrhiza glabra L. as a promisor candidacidal in biofilms and planktonic cells: comparison between phenolic extract and isolated compounds 2015
- In vitro study of the antifungal potential of Apiaceae hydroalcoholic extracts against Candida species 2014
- New perspectives of Juglans regia L. phytochemicals against Candida species 2014
- New di(hetero)arylthioethers 1,3-diarylureas in the thieno[3,2-b]pyridine series as VEGFR2 tyrosine kinase Inhibitors: docking, synthesis, enzymatic and cellular assays 2013
- Synthesis of new n-[3-(thieno[3,2-b]pyridine-7-ylthio)phenyl]benzamides as potential inhibitors of VEGFR2 using rational design 2013
- Gonoderma luicidium methanolic extract: chemical characterization in phenolic compounds and study of growth inhibitory activity in human tumor cell lines 2013
- Synthesis, docking, enzymatic and cellular assays of thieno[3,2-b]pyridine-thioether-1,3-diarylureas as VEGFR2 inhibitors 2013
- Synthesis, growth inhibitory activity on human tumor cell lines and evaluation of the hepatotoxicity of di(hetero)arylethers and di(hetero)arylamines in the thieno[3,2-b]pyridine series 2013
- Thieno[3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on human tumor cell lines 2013
- Heteroarylether 1,3-diarylureas in the thieno[3,2-d]pyrimidine series as VEGFR2 tyrosine kinase inhibitors: synthesis, docking studies, enzymatic and cellular assays 2013
- Antioxidant activity and phenolic compounds in decoction, infusion and hydroalcoholic extract of Origanum vulgare L. 2013
- Antioxidant activity of decoction, infusion and hydroalcoholic extract of cultivated thyme (Thymus vulgaris l.) 2013
- 1-Aryl-3-[4-(thieno[3,2-b]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 inhibitors: synthesis, docking, enzumatic and celular assays 2012
- Synthesis, growth inhibitory activity on human tumor cell lines and evaluation of the hepatotoxicity of di(hétero)arylethers and di(hétero)arylamines in the thieno[3,2-b]pyridine series 2012
- 1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 inhibitors: synthesis, docking enzymatic and cellular assays 2012
- Synthesis of novel 1-ary-3-[2-, 3- or 4-(thieno[3,2-b]pyridin-7-ylyhio)phenyl]ureas and evaluation as VEGFR2 tyrosine kinase inhibitors 2012
- Thieno [3,2-b]pyridine arylethers: synthesis and growth inhibitory activity on human tumor cell lines 2012
- Heteroarylether 1,3-diarylureas in the thieno[3,2-d]pyrimidine series as VEGFR2 tyrosine Kinase inhibitors: Synthesis, docking studies, enzymatic and cellular assays 2012
- 1-Aryl-3-[4-(thieno[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as VEGFR2 tyrosine kinase inhibitors: synthesis, docking, studies, enzymatic and cellular assays 2012
- Antifungal activity of natural extracts from Northeastern Portuguese flowers against Candida biofilms 2012
- Cistus ladanifer as a source of phenolic compounds with antifungal activity. Planta Medica. 2012
- Natural extracts from wild flowers used in Portuguese folk medicine like a new antifungal agents against Candida species 2012
- Screening of the antibacterial activity of phenolic extracts from Portuguese north-eastern plants 2012
- Synthesis of novel 1-Aryl-3-[2-,3- Or 4-(Thieno[3,2-b]Pyridin-7-Ylthio)Phenyl]Ureas and evaluation as VEGFR2 Tyrosine kinase inhibitors 2012
- Methyl 3-[4-(3-arylureido)phenylamino]thieno[3,2-b]pyridine-2-carboxylates as potential inhibitors of VEGFR-2: synthesis and molecular modelling studies 2011
- Methyl 3-amino-6-[4- or 3- or 2- (3-arylureido)phenyl]thieno[3,2-b]pyridine-2-carboxylates: synthesis and molecular modelling studies using VEGFR-2 2011
- Biodegradation of bioaccessible textile azo dyes by Phanerochaete chrysosporium 2000
- Biodegradation of textile azo dyes by Phanerochaete chrysosporium 1998